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The map label for this gene is xapB

Identifier: 51595546

GI number: 51595546

Start: 1432494

End: 1433750

Strand: Direct

Name: xapB

Synonym: YPTB1202

Alternate gene names: 51595546

Gene position: 1432494-1433750 (Clockwise)

Preceding gene: 51595545

Following gene: 51595548

Centisome position: 30.19

GC content: 43.44

Gene sequence:

>1257_bases
ATGATAATAAAAAAACGGCTTAAAGTTATGTTTTTCCTTCAGTTCTTTATCTGGGGTGCCTGGTTGGTGACGCTGGGCGC
TTACATGATGAATACGCTGAACTTTACCGGTGCACAGGTGGGTTTAGTCTATGGCGCTAAAGGCATCGCCTGTATTTTAA
TGCCGAGTCTGGTCGGTATTATTGCCGATCGATGGGTGAAAGCTAATATTCTCTATGCGTGTTGCCACCTGCTGGGGGCG
GTTGCGCTGTTGATCGCCGCCAATGTTTCAGACCCTAATATCATGTTCTTTGTGATGTTGTTCAATGCGATGGTCTATAT
GCCGACGATTGCACTGGCTAATACCATTTCTTATATCTGTTTAGAAAAAGCGGGGCTGGACACGATTAAAGATTTCCCCC
CGGTACGCGTCTTTGGCACCATTGGTTTTATTTTTGCCATGTGGGCTATCAGCCTCTCCGGATTTGAATTGAGTAATATC
CAGCTTTATATCGCTTCTGGTGCTGCGCTGGTGTTGGCGATATATGCTCTTTCATTACCAAGCTGTCCAACATCTAATAT
TAAAAAAGACCGCTCGTGGGTTAATATTTTAGGGCTTGATGCTTTCGTATTATTTAAACAAAAGAAAATGGCTATTTTCT
TCCTGTTTGCCATGTTACTTGGCGCTTCATTACAAATTAGCCACACGTTCAGCAGCCCCTTCCTCCATGACTTTGCAAAA
AATCCAATTTATCAGGATAGTCTGGTTGTCCAATACCCCTCGATCTTATTATCGATGGCCCAAATTGCAGAAGTCTTCTT
TATTCTGGCCATTCCCTTCTTCTTATCTCGCTTTGGTATCAAACGCGTGATGATGATCAGCATGATTGCCTGGACGCTGC
GCTTCACTCTATTTGCCTATGGCGATCCGTCGGCTACCGGTATTGTTTTATTACTGTTATCAATGGTGGTCTATGGTTGC
GCCTTTGATTTCTTTAATATCTCCGGTGCAATTTATGTTGAGAAAGAGGTCGATCATAATATCAGAGCCAGTGCGCAGGG
CCTGTTTATGACAATGGTTAACGGCGTGGGGGCTTATGTGGGTGCCATCACCAGTGGGCATGTGGTTGATTATTTCACTG
TTAATGGCGTCAAGGACTGGAATAGTATTTGGCTATCTTTTGCTGCTTACACCGTTATTCTGGTCATTGTTTTCTTCTTC
GTTTTTCAAGATAAACATGAGCCAACTGATCTAAAAAACCGCCAGTTATCCCATTAA

Upstream 100 bases:

>100_bases
TGCCAGCCGCAAATAGGGGCACCGTAAATGAGGGATATACCCTATAGGCTCAATGCGAAAAAATATATTCCTCGACGCAT
TTGAATCACGGAGAATAAAA

Downstream 100 bases:

>100_bases
TCATTATCGGGAGGAAGTCTACTCGTCCAAAATAGACTCTCCAGATAACCCCTGATTAATCAAATGTTAATCAGGGGAGT
TTCTATTTTATCGGCAACCT

Product: major facilitator superfamily xanthosine permease

Products: Proton [Cytoplasm]; xanthosine [Cytoplasm] [C]

Alternate protein names: Xanthosine transporter [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MIIKKRLKVMFFLQFFIWGAWLVTLGAYMMNTLNFTGAQVGLVYGAKGIACILMPSLVGIIADRWVKANILYACCHLLGA
VALLIAANVSDPNIMFFVMLFNAMVYMPTIALANTISYICLEKAGLDTIKDFPPVRVFGTIGFIFAMWAISLSGFELSNI
QLYIASGAALVLAIYALSLPSCPTSNIKKDRSWVNILGLDAFVLFKQKKMAIFFLFAMLLGASLQISHTFSSPFLHDFAK
NPIYQDSLVVQYPSILLSMAQIAEVFFILAIPFFLSRFGIKRVMMISMIAWTLRFTLFAYGDPSATGIVLLLLSMVVYGC
AFDFFNISGAIYVEKEVDHNIRASAQGLFMTMVNGVGAYVGAITSGHVVDYFTVNGVKDWNSIWLSFAAYTVILVIVFFF
VFQDKHEPTDLKNRQLSH

Sequences:

>Translated_418_residues
MIIKKRLKVMFFLQFFIWGAWLVTLGAYMMNTLNFTGAQVGLVYGAKGIACILMPSLVGIIADRWVKANILYACCHLLGA
VALLIAANVSDPNIMFFVMLFNAMVYMPTIALANTISYICLEKAGLDTIKDFPPVRVFGTIGFIFAMWAISLSGFELSNI
QLYIASGAALVLAIYALSLPSCPTSNIKKDRSWVNILGLDAFVLFKQKKMAIFFLFAMLLGASLQISHTFSSPFLHDFAK
NPIYQDSLVVQYPSILLSMAQIAEVFFILAIPFFLSRFGIKRVMMISMIAWTLRFTLFAYGDPSATGIVLLLLSMVVYGC
AFDFFNISGAIYVEKEVDHNIRASAQGLFMTMVNGVGAYVGAITSGHVVDYFTVNGVKDWNSIWLSFAAYTVILVIVFFF
VFQDKHEPTDLKNRQLSH
>Mature_418_residues
MIIKKRLKVMFFLQFFIWGAWLVTLGAYMMNTLNFTGAQVGLVYGAKGIACILMPSLVGIIADRWVKANILYACCHLLGA
VALLIAANVSDPNIMFFVMLFNAMVYMPTIALANTISYICLEKAGLDTIKDFPPVRVFGTIGFIFAMWAISLSGFELSNI
QLYIASGAALVLAIYALSLPSCPTSNIKKDRSWVNILGLDAFVLFKQKKMAIFFLFAMLLGASLQISHTFSSPFLHDFAK
NPIYQDSLVVQYPSILLSMAQIAEVFFILAIPFFLSRFGIKRVMMISMIAWTLRFTLFAYGDPSATGIVLLLLSMVVYGC
AFDFFNISGAIYVEKEVDHNIRASAQGLFMTMVNGVGAYVGAITSGHVVDYFTVNGVKDWNSIWLSFAAYTVILVIVFFF
VFQDKHEPTDLKNRQLSH

Specific function: Nucleoside transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli nupG and yegT [H]

Homologues:

Organism=Escherichia coli, GI1788745, Length=418, Percent_Identity=65.5502392344498, Blast_Score=547, Evalue=1e-157,
Organism=Escherichia coli, GI87082192, Length=418, Percent_Identity=55.2631578947368, Blast_Score=489, Evalue=1e-139,
Organism=Escherichia coli, GI1788415, Length=428, Percent_Identity=30.607476635514, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR004740 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46499; Mature: 46499

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIKKRLKVMFFLQFFIWGAWLVTLGAYMMNTLNFTGAQVGLVYGAKGIACILMPSLVGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHH
IADRWVKANILYACCHLLGAVALLIAANVSDPNIMFFVMLFNAMVYMPTIALANTISYIC
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKAGLDTIKDFPPVRVFGTIGFIFAMWAISLSGFELSNIQLYIASGAALVLAIYALSLP
HHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCEEECCEEEEEECCHHHHHHHHHHCCC
SCPTSNIKKDRSWVNILGLDAFVLFKQKKMAIFFLFAMLLGASLQISHTFSSPFLHDFAK
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHC
NPIYQDSLVVQYPSILLSMAQIAEVFFILAIPFFLSRFGIKRVMMISMIAWTLRFTLFAY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GDPSATGIVLLLLSMVVYGCAFDFFNISGAIYVEKEVDHNIRASAQGLFMTMVNGVGAYV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
GAITSGHVVDYFTVNGVKDWNSIWLSFAAYTVILVIVFFFVFQDKHEPTDLKNRQLSH
HHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIIKKRLKVMFFLQFFIWGAWLVTLGAYMMNTLNFTGAQVGLVYGAKGIACILMPSLVGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHH
IADRWVKANILYACCHLLGAVALLIAANVSDPNIMFFVMLFNAMVYMPTIALANTISYIC
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKAGLDTIKDFPPVRVFGTIGFIFAMWAISLSGFELSNIQLYIASGAALVLAIYALSLP
HHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCEEECCEEEEEECCHHHHHHHHHHCCC
SCPTSNIKKDRSWVNILGLDAFVLFKQKKMAIFFLFAMLLGASLQISHTFSSPFLHDFAK
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHC
NPIYQDSLVVQYPSILLSMAQIAEVFFILAIPFFLSRFGIKRVMMISMIAWTLRFTLFAY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GDPSATGIVLLLLSMVVYGCAFDFFNISGAIYVEKEVDHNIRASAQGLFMTMVNGVGAYV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
GAITSGHVVDYFTVNGVKDWNSIWLSFAAYTVILVIVFFFVFQDKHEPTDLKNRQLSH
HHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; xanthosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + xanthosine [Periplasm] = Proton [Cytoplasm] + xanthosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7559336; 9205837; 9278503 [H]