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The map label for this gene is dcuB

Identifier: 51595189

GI number: 51595189

Start: 1005686

End: 1007029

Strand: Reverse

Name: dcuB

Synonym: YPTB0839

Alternate gene names: 51595189

Gene position: 1007029-1005686 (Counterclockwise)

Preceding gene: 51595190

Following gene: 51595188

Centisome position: 21.22

GC content: 46.06

Gene sequence:

>1344_bases
ATGATAACTCTACAATTTATAATTATAATTCTATGTTTGCTGTTAGGTACGCGTTACGGAGGGATGGGGCTGGGGTTAAT
AAGTGGTATCGGCTTATTTATTCTGACCTTTATCTTTGGCCTCGAACCAGGAAAACCACCTGTAGATGTAATGCTAACAA
TATTAGCGGTTATTGGTTGTGCTTCAGTACTACAAACCGCAGGCGGGTTAAATGTAATGATGCAATTTGCCGAGCGATTA
TTACGCCGCCACCCACAGCACATTACGTTATTAGCGCCCTTCACGACGTGGTCATTAACCTTTCTTTGCGGCACCGGACA
TGTCGTTTACACCATGTTCCCCATAATTTCCGACATCGCCATTAAAAAAGGTATTCGTCCAGAACGACCAATGGCGGTTG
CATCCGTTGCCTCACAGATGGCAATTACGGCATCTCCAGTATCGGTTGCTGTCGTATCATTAGTTTCAATTATTGGTGCT
AACCATGGCATCGGCCATGCCTATAGCATTCTGGAAATTCTGGCTATTTCAGTTCCCGCCTCTTTGGTTGGAGTGCTAAT
CGCAGCCCTGTGGAGCCTGCGCCGTGGTAAAGATCTGGATAAAGATCCTGATTTTCAGGAAAAAATAAAAGATCCAGAGC
AGCGGGCCTATATATATGGCTCAACAGATACGTTGCTGAATCAGGTTTTTCCAAAACAAGCTTATTGGTCGACCTGGATA
TTCTTTGCCGCTATCGTCGTTGTCGTCTTGTTGGGCGCTTTTGCAGACCTGCGCCCTGCTTTTGAAGTTAAAGGCAAGTT
ACAGTCTTTGTCGATGAATCTGGTGATTCAGATGATGATGCTGATCGCCGGTGCCGTTATTTTGATTGGCTGCAAAGTCA
AACCCAGTGATATCTCTAACGGTGCCGTATTCAAAGCCGGAATGGTTGCTATCTTCTCGGTATTCGGCGTTGCCTGGATG
AGTGACACCTTCTTCCAGGCTCATATGGGTGAACTGAGATTAGTACTGGAAGATGTGGTAAAAGGCCACCCTTGGACTTA
TGCCATTGTGCTGTTCTTAGTCTCGAAGCTGGTGAACAGCCAAGCCGCGGCGCTAGCAGCGATCGCACCAATGGGCTTAC
AATTAGGCGTTGAACCTAAGATGCTCATCGCATTTTTCCCAGCAGCTTACGGATATTTTGTTCTGCCAACCTACCCGAGT
GATCTGGCTTGTATCGGTTTTGACCGCTCTGGTACCACCAAAATTGGTAGATTCATTATCAACCATAGCTTTATCATTCC
AGGTCTTATTGGCGTCATTTGCTCCTGTATCACGGGCTATCTGCTGGTAACGACGTTTATGTAG

Upstream 100 bases:

>100_bases
TCTGTGCTCTGATAAGAGAAATCGAGTAAGGATTATAGTCATCGAATAAAACCAACAAATACATAACCGAATTTCATTCA
TATTTGAAGCGAGGGACATC

Downstream 100 bases:

>100_bases
TGAATCATAAATCCAGGAGTCTACTTTGTAGGGCCAGTGTATTTTCTGGCTCTTAATCCCCTTCTAATTTGACGCTGCCA
CAGTATTAATGGCATTCATT

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MITLQFIIIILCLLLGTRYGGMGLGLISGIGLFILTFIFGLEPGKPPVDVMLTILAVIGCASVLQTAGGLNVMMQFAERL
LRRHPQHITLLAPFTTWSLTFLCGTGHVVYTMFPIISDIAIKKGIRPERPMAVASVASQMAITASPVSVAVVSLVSIIGA
NHGIGHAYSILEILAISVPASLVGVLIAALWSLRRGKDLDKDPDFQEKIKDPEQRAYIYGSTDTLLNQVFPKQAYWSTWI
FFAAIVVVVLLGAFADLRPAFEVKGKLQSLSMNLVIQMMMLIAGAVILIGCKVKPSDISNGAVFKAGMVAIFSVFGVAWM
SDTFFQAHMGELRLVLEDVVKGHPWTYAIVLFLVSKLVNSQAAALAAIAPMGLQLGVEPKMLIAFFPAAYGYFVLPTYPS
DLACIGFDRSGTTKIGRFIINHSFIIPGLIGVICSCITGYLLVTTFM

Sequences:

>Translated_447_residues
MITLQFIIIILCLLLGTRYGGMGLGLISGIGLFILTFIFGLEPGKPPVDVMLTILAVIGCASVLQTAGGLNVMMQFAERL
LRRHPQHITLLAPFTTWSLTFLCGTGHVVYTMFPIISDIAIKKGIRPERPMAVASVASQMAITASPVSVAVVSLVSIIGA
NHGIGHAYSILEILAISVPASLVGVLIAALWSLRRGKDLDKDPDFQEKIKDPEQRAYIYGSTDTLLNQVFPKQAYWSTWI
FFAAIVVVVLLGAFADLRPAFEVKGKLQSLSMNLVIQMMMLIAGAVILIGCKVKPSDISNGAVFKAGMVAIFSVFGVAWM
SDTFFQAHMGELRLVLEDVVKGHPWTYAIVLFLVSKLVNSQAAALAAIAPMGLQLGVEPKMLIAFFPAAYGYFVLPTYPS
DLACIGFDRSGTTKIGRFIINHSFIIPGLIGVICSCITGYLLVTTFM
>Mature_447_residues
MITLQFIIIILCLLLGTRYGGMGLGLISGIGLFILTFIFGLEPGKPPVDVMLTILAVIGCASVLQTAGGLNVMMQFAERL
LRRHPQHITLLAPFTTWSLTFLCGTGHVVYTMFPIISDIAIKKGIRPERPMAVASVASQMAITASPVSVAVVSLVSIIGA
NHGIGHAYSILEILAISVPASLVGVLIAALWSLRRGKDLDKDPDFQEKIKDPEQRAYIYGSTDTLLNQVFPKQAYWSTWI
FFAAIVVVVLLGAFADLRPAFEVKGKLQSLSMNLVIQMMMLIAGAVILIGCKVKPSDISNGAVFKAGMVAIFSVFGVAWM
SDTFFQAHMGELRLVLEDVVKGHPWTYAIVLFLVSKLVNSQAAALAAIAPMGLQLGVEPKMLIAFFPAAYGYFVLPTYPS
DLACIGFDRSGTTKIGRFIINHSFIIPGLIGVICSCITGYLLVTTFM

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790565, Length=410, Percent_Identity=57.8048780487805, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1790580, Length=444, Percent_Identity=37.1621621621622, Blast_Score=278, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 48252; Mature: 48252

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLQFIIIILCLLLGTRYGGMGLGLISGIGLFILTFIFGLEPGKPPVDVMLTILAVIGC
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ASVLQTAGGLNVMMQFAERLLRRHPQHITLLAPFTTWSLTFLCGTGHVVYTMFPIISDIA
HHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHEEEEEECCCHHHHHHHHHHHHHH
IKKGIRPERPMAVASVASQMAITASPVSVAVVSLVSIIGANHGIGHAYSILEILAISVPA
HHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCH
SLVGVLIAALWSLRRGKDLDKDPDFQEKIKDPEQRAYIYGSTDTLLNQVFPKQAYWSTWI
HHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHCEEEECCHHHHHHHHCCCHHHHHHHH
FFAAIVVVVLLGAFADLRPAFEVKGKLQSLSMNLVIQMMMLIAGAVILIGCKVKPSDISN
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
GAVFKAGMVAIFSVFGVAWMSDTFFQAHMGELRLVLEDVVKGHPWTYAIVLFLVSKLVNS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QAAALAAIAPMGLQLGVEPKMLIAFFPAAYGYFVLPTYPSDLACIGFDRSGTTKIGRFII
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCHHHHHHHH
NHSFIIPGLIGVICSCITGYLLVTTFM
CCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITLQFIIIILCLLLGTRYGGMGLGLISGIGLFILTFIFGLEPGKPPVDVMLTILAVIGC
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ASVLQTAGGLNVMMQFAERLLRRHPQHITLLAPFTTWSLTFLCGTGHVVYTMFPIISDIA
HHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHEEEEEECCCHHHHHHHHHHHHHH
IKKGIRPERPMAVASVASQMAITASPVSVAVVSLVSIIGANHGIGHAYSILEILAISVPA
HHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCH
SLVGVLIAALWSLRRGKDLDKDPDFQEKIKDPEQRAYIYGSTDTLLNQVFPKQAYWSTWI
HHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHCEEEECCHHHHHHHHCCCHHHHHHHH
FFAAIVVVVLLGAFADLRPAFEVKGKLQSLSMNLVIQMMMLIAGAVILIGCKVKPSDISN
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
GAVFKAGMVAIFSVFGVAWMSDTFFQAHMGELRLVLEDVVKGHPWTYAIVLFLVSKLVNS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QAAALAAIAPMGLQLGVEPKMLIAFFPAAYGYFVLPTYPSDLACIGFDRSGTTKIGRFII
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCHHHHHHHH
NHSFIIPGLIGVICSCITGYLLVTTFM
CCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]