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The map label for this gene is yrhP [H]

Identifier: 51594976

GI number: 51594976

Start: 743953

End: 744567

Strand: Reverse

Name: yrhP [H]

Synonym: YPTB0625

Alternate gene names: 51594976

Gene position: 744567-743953 (Counterclockwise)

Preceding gene: 51594982

Following gene: 51594966

Centisome position: 15.69

GC content: 48.62

Gene sequence:

>615_bases
ATGCTTGAAACCTCGTTATTCGTCGCGACACTCGCGACATTGGGAATGATCTCCCCCGGACCTGATTTTTTTCTGGTGAT
CAAAAACGCTGCCCGCTATCGCCGCACTGCCGCCATGATGACGGCACTTGGTGTAATTTTGGGTGTTGCAACGCATATGT
CTTACTGCGTGGCCGGTCTGGCGGTCGTTATCACGACTACACCATGGTTATTCAATTTGCTGAAATATGCCGGGGCCTGC
TACCTGATCTGGATTGGTATTCAAGCACTGCTGTCACGGGGAGAAAGTAAGTTTAGTATTGATAATACTGCACAGTATCC
CATCTCGCTCAAAGCCGCATTTTTGCAAGGTTACCTCTGCAACTTATTGAATCCCAAAGCAACTCTTTTCTTCCTCGCCG
TTTTCACGCAAATATTGCAGATAAACTCCGGCATAGGAGAAAAACTCTGGTATGCCTCAATCATCTGGATACTGTCCGCA
ATCTGGTGGCCTGTGCTGGTGATCCTGATCCAAAGCGCGCCAGTACGCCGTGGTTTAGCCAAAACACAAAAAGTGGTCGA
TAAAGTGTTAGGCGGCCTGTTGATCGGCCTTGGCATCAAAGTCGCATTAGGCTAA

Upstream 100 bases:

>100_bases
CTAATAACAAAATGGCATCAGATAACCAATAAGAGTAATGCAAAGAATGCTAAGTGGCGTTATTATCGCCAGATTGCTTC
ACTCCCATTCGGTAATTAAG

Downstream 100 bases:

>100_bases
CACCGCTATCAACCCCAGCATCTCGGTTAAGTATTTCGCTACTGAGATGGCCATCTACAATGACCGTTTACTATCCACAA
TAGTGTTGGCAATAACATTG

Product: RhtB/LysE family threonine efflux pump

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMMTALGVILGVATHMSYCVAGLAVVITTTPWLFNLLKYAGAC
YLIWIGIQALLSRGESKFSIDNTAQYPISLKAAFLQGYLCNLLNPKATLFFLAVFTQILQINSGIGEKLWYASIIWILSA
IWWPVLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG

Sequences:

>Translated_204_residues
MLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMMTALGVILGVATHMSYCVAGLAVVITTTPWLFNLLKYAGAC
YLIWIGIQALLSRGESKFSIDNTAQYPISLKAAFLQGYLCNLLNPKATLFFLAVFTQILQINSGIGEKLWYASIIWILSA
IWWPVLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG
>Mature_204_residues
MLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMMTALGVILGVATHMSYCVAGLAVVITTTPWLFNLLKYAGAC
YLIWIGIQALLSRGESKFSIDNTAQYPISLKAAFLQGYLCNLLNPKATLFFLAVFTQILQINSGIGEKLWYASIIWILSA
IWWPVLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=204, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1786522, Length=199, Percent_Identity=30.1507537688442, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1788099, Length=184, Percent_Identity=33.1521739130435, Blast_Score=80, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22166; Mature: 22166

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMMTALGVILGVATHMSYCVAGL
CCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFSIDNTAQYPISLKAAFLQGYLC
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
NLLNPKATLFFLAVFTQILQINSGIGEKLWYASIIWILSAIWWPVLVILIQSAPVRRGLA
HHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KTQKVVDKVLGGLLIGLGIKVALG
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMMTALGVILGVATHMSYCVAGL
CCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFSIDNTAQYPISLKAAFLQGYLC
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
NLLNPKATLFFLAVFTQILQINSGIGEKLWYASIIWILSAIWWPVLVILIQSAPVRRGLA
HHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KTQKVVDKVLGGLLIGLGIKVALG
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]