Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 51594828

GI number: 51594828

Start: 560895

End: 562235

Strand: Direct

Name: glmM

Synonym: YPTB0476

Alternate gene names: 51594828

Gene position: 560895-562235 (Clockwise)

Preceding gene: 51594827

Following gene: 51594829

Centisome position: 11.82

GC content: 47.73

Gene sequence:

>1341_bases
ATGAGTAACCGTAAATACTTTGGTACAGATGGCATTCGCGGTAAAGTGGGTGAAAGTCCGATTACTCCGGATTTTGTATT
GAAGCTTGGCTGGGCTGCCGGTAAGGTTCTGGCACGACATGGTTCTCGTAAAATTATTATCGGTAAAGACACTCGCATAT
CTGGTTATATGCTGGAATCAGCACTTGAGGCGGGCCTGGCAGCCGCTGGGCTATCTGCGCTATTTACTGGGCCGATGCCC
ACACCCGCTGTTGCTTATTTGACACGTACCTTCCGCGCTGAAGCGGGTATTGTAATTTCTGCTTCTCATAACCCTTTCTA
TGATAACGGTATTAAGTTTTTCTCCATTGATGGCACCAAATTGCCTGATGATGTGGAAGAGGCTATTGAAGCCGAAATGG
AAAAACCGCTGACTTGTGTTGAATCCGCTGAGTTGGGAAAAGCTAACCGTATTGTTGATGCTGCTGGTCGTTACATTGAG
TTCTGCAAAGGGACATTCCCAAGCGAACTTAGCCTGAATGAGCTGAAAATAGTGGTCGATTGTGCCAATGGTGCTACGTA
TCACATCGCACCAAGCGTATTACGTGAATTGGGCGCGACAGTGATTACCATCGGCTGTGAACCTGATGGTATGAACATCA
ACGAAGAGTGTGGTGCTACAGACGTTCGTTTGCTGCAAGAACGTGTTCTTGCCGAAGGGGCTCACGTAGGCTTGGCATTC
GATGGGGATGGCGATCGGCTGATGATGGTTGACCATTTGGGGAATAAAGTTGATGGTGACCAAATTCTGTACATTATTGC
GCGTGAAGGCTTACGCCAAGGTCAATTGAAAGGCGGTGCGGTTGGCACGCTAATGAGTAACATGGGCCTTCAATTAGCCC
TGAAAGATCTGGGTATCCCATTTGTTCGTGCCAAAGTGGGCGATCGCTATGTCTTGGAAGCGATGCAAGAGAAAGGCTGG
CGTATTGGTGCAGAAAACTCGGGTCATGTAATTTTATTGGATAAAACCACCACTGGCGATGGGATTGTGGCAGGTTTGCA
AGTGCTCACCGCCATGGTTCGTAACCATATGAGTTTGCATGACCTGTGTAGTGGCATGAAGTTATTACCACAAATTTTGG
TAAATGTGCGTTTCTCCGGCGAGCATAATCCACTGAAATCTGATGAAGTTGAAGAAGTGACCCGGCAGGTGGAAAAAGAA
TTGGGTGGCCGTGGCCGGGTTCTATTACGTAAATCGGGTACTGAACCACTCATTCGCGTCATGGTTGAAGGTGATGCGGA
AGAATCACTGATAGCTGAAATGGCAAACCGGATTGCTGATGCAGTAAAGGCAGCAGGTTAA

Upstream 100 bases:

>100_bases
GCAAGGTGCGCAGATTATCAGAGTGCATGATGTCAAAGAAACTGTCGAGGCGATGTGTATCGTCGAGGCAACACGTTCAG
CGAAGGGATAAAGATAAATT

Downstream 100 bases:

>100_bases
CCCTTTTTTAAAGGGGGAGAGGCACTCTTCCCCAAGAAATTACGCTGAAGTTGAATAACTTGACGCTTTTTTCTGCAAAT
AAACCCATGTGATGAAATTG

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSNRKYFGTDGIRGKVGESPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMP
TPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKPLTCVESAELGKANRIVDAAGRYIE
FCKGTFPSELSLNELKIVVDCANGATYHIAPSVLRELGATVITIGCEPDGMNINEECGATDVRLLQERVLAEGAHVGLAF
DGDGDRLMMVDHLGNKVDGDQILYIIAREGLRQGQLKGGAVGTLMSNMGLQLALKDLGIPFVRAKVGDRYVLEAMQEKGW
RIGAENSGHVILLDKTTTGDGIVAGLQVLTAMVRNHMSLHDLCSGMKLLPQILVNVRFSGEHNPLKSDEVEEVTRQVEKE
LGGRGRVLLRKSGTEPLIRVMVEGDAEESLIAEMANRIADAVKAAG

Sequences:

>Translated_446_residues
MSNRKYFGTDGIRGKVGESPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMP
TPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKPLTCVESAELGKANRIVDAAGRYIE
FCKGTFPSELSLNELKIVVDCANGATYHIAPSVLRELGATVITIGCEPDGMNINEECGATDVRLLQERVLAEGAHVGLAF
DGDGDRLMMVDHLGNKVDGDQILYIIAREGLRQGQLKGGAVGTLMSNMGLQLALKDLGIPFVRAKVGDRYVLEAMQEKGW
RIGAENSGHVILLDKTTTGDGIVAGLQVLTAMVRNHMSLHDLCSGMKLLPQILVNVRFSGEHNPLKSDEVEEVTRQVEKE
LGGRGRVLLRKSGTEPLIRVMVEGDAEESLIAEMANRIADAVKAAG
>Mature_445_residues
SNRKYFGTDGIRGKVGESPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPT
PAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKPLTCVESAELGKANRIVDAAGRYIEF
CKGTFPSELSLNELKIVVDCANGATYHIAPSVLRELGATVITIGCEPDGMNINEECGATDVRLLQERVLAEGAHVGLAFD
GDGDRLMMVDHLGNKVDGDQILYIIAREGLRQGQLKGGAVGTLMSNMGLQLALKDLGIPFVRAKVGDRYVLEAMQEKGWR
IGAENSGHVILLDKTTTGDGIVAGLQVLTAMVRNHMSLHDLCSGMKLLPQILVNVRFSGEHNPLKSDEVEEVTRQVEKEL
GGRGRVLLRKSGTEPLIRVMVEGDAEESLIAEMANRIADAVKAAG

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1789566, Length=445, Percent_Identity=85.6179775280899, Blast_Score=749, Evalue=0.0,
Organism=Escherichia coli, GI1788361, Length=465, Percent_Identity=27.3118279569892, Blast_Score=108, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17535441, Length=344, Percent_Identity=28.4883720930233, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323752, Length=285, Percent_Identity=26.3157894736842, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 47899; Mature: 47768

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRKYFGTDGIRGKVGESPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTK
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCC
LPDDVEEAIEAEMEKPLTCVESAELGKANRIVDAAGRYIEFCKGTFPSELSLNELKIVVD
CCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
CANGATYHIAPSVLRELGATVITIGCEPDGMNINEECGATDVRLLQERVLAEGAHVGLAF
CCCCCEEEECHHHHHHCCCEEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHCCCEEEEEE
DGDGDRLMMVDHLGNKVDGDQILYIIAREGLRQGQLKGGAVGTLMSNMGLQLALKDLGIP
ECCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEHHHCCCC
FVRAKVGDRYVLEAMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLTAMVRNHMSLH
EEEHHCCCHHHHHHHHHCCCEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHH
DLCSGMKLLPQILVNVRFSGEHNPLKSDEVEEVTRQVEKELGGRGRVLLRKSGTEPLIRV
HHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
MVEGDAEESLIAEMANRIADAVKAAG
EECCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNRKYFGTDGIRGKVGESPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTK
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCC
LPDDVEEAIEAEMEKPLTCVESAELGKANRIVDAAGRYIEFCKGTFPSELSLNELKIVVD
CCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
CANGATYHIAPSVLRELGATVITIGCEPDGMNINEECGATDVRLLQERVLAEGAHVGLAF
CCCCCEEEECHHHHHHCCCEEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHCCCEEEEEE
DGDGDRLMMVDHLGNKVDGDQILYIIAREGLRQGQLKGGAVGTLMSNMGLQLALKDLGIP
ECCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEHHHCCCC
FVRAKVGDRYVLEAMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLTAMVRNHMSLH
EEEHHCCCHHHHHHHHHCCCEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHH
DLCSGMKLLPQILVNVRFSGEHNPLKSDEVEEVTRQVEKELGGRGRVLLRKSGTEPLIRV
HHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
MVEGDAEESLIAEMANRIADAVKAAG
EECCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA