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The map label for this gene is dcuA

Identifier: 51594753

GI number: 51594753

Start: 478680

End: 479981

Strand: Reverse

Name: dcuA

Synonym: YPTB0401

Alternate gene names: 51594753

Gene position: 479981-478680 (Counterclockwise)

Preceding gene: 51594754

Following gene: 51594752

Centisome position: 10.12

GC content: 51.23

Gene sequence:

>1302_bases
ATGATAGCCGTAGAATTAGTCATCGTTCTGCTGGCCATTTTTCTTGGGGCCAGGTTAGGGGGTATTGGTATAGGTTTTGC
AGGCGGAATTGGTGTTCTGGTATTGGCGATCATTGGTGTCAAACCCGGCAGTATCCCGTTTGATGTTATTTCAATCATCA
TGGCGGTGATTGCCGCTATCTCTGCGATGCAAGTTGCAGGGGGGATGGATTATCTGGTGCAGCAAACTGAAAAGTTACTG
CGTAAGAACCCAAAACACATCACCATTCTTGCGCCGCTGGTCACTTATTTTCTGACCATCTTCGCCGGGACCGGTAACAT
TTCGCTGTCAGCTCTGCCAGTCATTGCCGAAGTCGCGAAAGAACAGGGCATCAAACCTTGCCGCCCACTGTCTACCGCTG
TCGTTTCCGCACAGATAGCCATTACCGCATCCCCGATTTCTGCGGCAGTGGTATATATGTCTTCGGTCATGGAAGGCCAG
GGTGTCAGCTATTTACATCTGCTGATGATCGTTATTCCCTCCACCCTTTGTGCCGTATTGGTGATGTCTCTCATCGTCTC
TTGGTGCTTTAGCTCCAAGCTGTCCGATGATCCTATTTACCTGAAACGTTTGGAAGAAGGTTTAGTCACCCTGCGTGGCG
ACACCGTAAAAGTGATCAAACCACGGGCGAAAACTTCCGTTCTGCTGTTCCTGGCTGGGGTACTTTGTGTGGTGGCTTAT
GCGATCATCAACAGCCCAAGTGTTGGGCTCGTTGAAACGCCGCTGATGAACACCACTAACGCTATCCTGATCATCATGCT
GAGTGTCGCTACCATCACCACGCTGGTCTGCTCGGTTGATACGGATTCGATCTTGAACTCCAGCACCTTCAAAGCCGGTA
TGAGCGCTTGTATCTGTATCCTGGGTGTGGCCTGGTTGGGTGATACCTTTGTACAACACAACCTTGAGTGGATTAAAGAG
ACCGCGGGTAGCTTGATTCAAGCGCACTCATGGTTACTGGCTGTGATTTTCTTCTTCTGCTCCGCCCTGCTTTACTCTCA
AGCTGCAACCGCCAAGGCATTAATGCCAATGGCGCTGGCGCTGAACGTTTCACCATTGGCGGCAATTGCCTCTTTCGCGG
CAGTTTCTGGCCTGTTCATCCTGCCAACCTACCCAACACTGGTGGCTGCGGTGCAAATGGATGACACAGGGACCACCCGT
ATTGGTCGCTTTGTGTTTAACCACCCGTTCTTTATCCCTGGCACCATCGGGGTTGCACTGGCCGTTTGTTTCGGCTTTGT
GATGGGCGGTCTGGTTCTGTAA

Upstream 100 bases:

>100_bases
TCTAAGGCACGCATGCTCCTCTGGACAGCGTGCCTTTTTACTTTCTGGCAAACACAATTTTTTAACTTTTACGTTCAAAT
TTAAACAAGGAGTAAACACT

Downstream 100 bases:

>100_bases
TCTGTCTGATGGGGCGCATCATGCGCCCCAATAACTTCGGTCTATCTCTCACCGTTACATAAATCATCTTCTGGCTGGCC
CCGGCTTCGGGGTATAGTAT

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIAVELVIVLLAIFLGARLGGIGIGFAGGIGVLVLAIIGVKPGSIPFDVISIIMAVIAAISAMQVAGGMDYLVQQTEKLL
RKNPKHITILAPLVTYFLTIFAGTGNISLSALPVIAEVAKEQGIKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGQ
GVSYLHLLMIVIPSTLCAVLVMSLIVSWCFSSKLSDDPIYLKRLEEGLVTLRGDTVKVIKPRAKTSVLLFLAGVLCVVAY
AIINSPSVGLVETPLMNTTNAILIIMLSVATITTLVCSVDTDSILNSSTFKAGMSACICILGVAWLGDTFVQHNLEWIKE
TAGSLIQAHSWLLAVIFFFCSALLYSQAATAKALMPMALALNVSPLAAIASFAAVSGLFILPTYPTLVAAVQMDDTGTTR
IGRFVFNHPFFIPGTIGVALAVCFGFVMGGLVL

Sequences:

>Translated_433_residues
MIAVELVIVLLAIFLGARLGGIGIGFAGGIGVLVLAIIGVKPGSIPFDVISIIMAVIAAISAMQVAGGMDYLVQQTEKLL
RKNPKHITILAPLVTYFLTIFAGTGNISLSALPVIAEVAKEQGIKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGQ
GVSYLHLLMIVIPSTLCAVLVMSLIVSWCFSSKLSDDPIYLKRLEEGLVTLRGDTVKVIKPRAKTSVLLFLAGVLCVVAY
AIINSPSVGLVETPLMNTTNAILIIMLSVATITTLVCSVDTDSILNSSTFKAGMSACICILGVAWLGDTFVQHNLEWIKE
TAGSLIQAHSWLLAVIFFFCSALLYSQAATAKALMPMALALNVSPLAAIASFAAVSGLFILPTYPTLVAAVQMDDTGTTR
IGRFVFNHPFFIPGTIGVALAVCFGFVMGGLVL
>Mature_433_residues
MIAVELVIVLLAIFLGARLGGIGIGFAGGIGVLVLAIIGVKPGSIPFDVISIIMAVIAAISAMQVAGGMDYLVQQTEKLL
RKNPKHITILAPLVTYFLTIFAGTGNISLSALPVIAEVAKEQGIKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGQ
GVSYLHLLMIVIPSTLCAVLVMSLIVSWCFSSKLSDDPIYLKRLEEGLVTLRGDTVKVIKPRAKTSVLLFLAGVLCVVAY
AIINSPSVGLVETPLMNTTNAILIIMLSVATITTLVCSVDTDSILNSSTFKAGMSACICILGVAWLGDTFVQHNLEWIKE
TAGSLIQAHSWLLAVIFFFCSALLYSQAATAKALMPMALALNVSPLAAIASFAAVSGLFILPTYPTLVAAVQMDDTGTTR
IGRFVFNHPFFIPGTIGVALAVCFGFVMGGLVL

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=433, Percent_Identity=85.2193995381062, Blast_Score=709, Evalue=0.0,
Organism=Escherichia coli, GI1790565, Length=408, Percent_Identity=35.7843137254902, Blast_Score=239, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 45437; Mature: 45437

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVELVIVLLAIFLGARLGGIGIGFAGGIGVLVLAIIGVKPGSIPFDVISIIMAVIAAI
CHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
SAMQVAGGMDYLVQQTEKLLRKNPKHITILAPLVTYFLTIFAGTGNISLSALPVIAEVAK
HHHHHHCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
EQGIKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGQGVSYLHLLMIVIPSTLCAVL
HCCCCCCCCHHHHHHHEEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VMSLIVSWCFSSKLSDDPIYLKRLEEGLVTLRGDTVKVIKPRAKTSVLLFLAGVLCVVAY
HHHHHHHHHHCCCCCCCHHHHHHHHHCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHH
AIINSPSVGLVETPLMNTTNAILIIMLSVATITTLVCSVDTDSILNSSTFKAGMSACICI
HHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHH
LGVAWLGDTFVQHNLEWIKETAGSLIQAHSWLLAVIFFFCSALLYSQAATAKALMPMALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNVSPLAAIASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGRFVFNHPFFIPGTIGVAL
CCCHHHHHHHHHHHHCCEEEECCCHHHHEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHH
AVCFGFVMGGLVL
HHHHHHHHHHHCC
>Mature Secondary Structure
MIAVELVIVLLAIFLGARLGGIGIGFAGGIGVLVLAIIGVKPGSIPFDVISIIMAVIAAI
CHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
SAMQVAGGMDYLVQQTEKLLRKNPKHITILAPLVTYFLTIFAGTGNISLSALPVIAEVAK
HHHHHHCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
EQGIKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGQGVSYLHLLMIVIPSTLCAVL
HCCCCCCCCHHHHHHHEEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VMSLIVSWCFSSKLSDDPIYLKRLEEGLVTLRGDTVKVIKPRAKTSVLLFLAGVLCVVAY
HHHHHHHHHHCCCCCCCHHHHHHHHHCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHH
AIINSPSVGLVETPLMNTTNAILIIMLSVATITTLVCSVDTDSILNSSTFKAGMSACICI
HHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHH
LGVAWLGDTFVQHNLEWIKETAGSLIQAHSWLLAVIFFFCSALLYSQAATAKALMPMALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNVSPLAAIASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGRFVFNHPFFIPGTIGVAL
CCCHHHHHHHHHHHHCCEEEECCCHHHHEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHH
AVCFGFVMGGLVL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]