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The map label for this gene is yscC [H]

Identifier: 51594667

GI number: 51594667

Start: 380872

End: 382443

Strand: Direct

Name: yscC [H]

Synonym: YPTB0312

Alternate gene names: 51594667

Gene position: 380872-382443 (Clockwise)

Preceding gene: 51594664

Following gene: 51594668

Centisome position: 8.03

GC content: 43.26

Gene sequence:

>1572_bases
TTGATAGTCGGTTTACGCCAAAAACCGTATTTAAATTTAAGAAATTATAAGTGGATGTCGCTAATCTATATCATGAGAAA
AATAACGGGTCTGATATTACTTTTTTTTGCCACATTGTTGCCTTATGGGAAATTTTCTTATGGAAAAGCGATTCCTTGGC
AAGGCGAGCCTTTTTTTATTTATAGCCGAGGCATGACAGTTTCTGAATTATTAAAAGATTTGGGGATGAATTACGGTATT
CCTGTGGTGATCAGTTCGGAAATAAACGAGCACTTTACTGGAAAGATTAGGGATAAGACACCTGAAAAAATCCTATCGGA
GTTGGCTGGGCGATATAATATAACGTGGTATTACGATGGTGAAACACTCTATTTTTACCCAGTTCAATCAATCAAGCGGG
AGTTTATATCCCCCGATGGTCTGGCTGCCAATACGTTAGTTAAATATCTCCAGCGCGGTGACGTGCTGGCGGGGAAAAAC
TGTGCCATAAAAGCGATCCCCCACCTTGATACCCTTGAGGTCAAGGGAGTGCCTATCTGCATCGAACGCGTAAAGTCAGT
AAGCAAAATGCTTTCTGAGCAAGTTCGTCACCAAAACCAAAATAAAGAAACAGTGAAAGTTTTCCCGCTGAAATATGCTT
CAGCAGCGGATTCAGATTATCAGTACCGAGATCAAAACGTCAGATTACCGGGGTTGGTCAGTGTGTTACGTGAGTTGAAC
CAAGGGAATAATTTGCCTTTGGCGGGCGGTAACCAACCAGATGGAAATCAAGCAAGCTCACCGGTGTTTTCGGCTGATCC
TCGGCAAAATGCCGTCATTATTCGCGATCGCCAGGCTAATATGCCGATTTATCGCAGCTTGATTACCCAACTGGATCAGC
GGCCAATTCAGATAGAAATTTCTGTCACTATTATTGATGTTGATGCGGGAGATATCAGCCAACTGGGTGTTGATTGGTCT
GCATCTGCTTCTATTGGTGGAACGGGGGTCTCATTTAATAGCACCTTCGCCAAGAATAATGCTGAAGGCTTTTCTACCGT
GATTGGTGATACGGGGAACTTTATGGTTCGTCTGAATGCGTTACAAAAAAATTCACGAGCCAGAATTTTATCTCAACCTT
CAGTGGTGACCCTGAACAATATTCAGGCGGTACTGGATAAAAACGTGACGTTTTATACCAAGCTGCAAGGTGAGAAAGTG
GCCAAACTTGAATCTGTCACTTCAGGGTCATTACTGCGAGTGACGCCAAGAATGATCGAGACCGAAGGGGTACAAGAGGT
TTTACTTAATCTCAATATTCAGGATGGTCAGCAGCAAGCTTCTACCAATAGTAATGAGCCATTACCCGAAATACGAAACT
CAGATATTTCGACGCAGGCCACGCTACAGGTTGGACAAAGTTTACTCTTGGGCGGATTTATTCAGGACACGCAGATTGAG
TCACAAAATAAAATTCCTTTACTGGGCGATATTCCGCTATTAGGTGGGTTGTTCCGTAGTACAGATAAACAATCTCACAG
CGTGGTCAGACTCTTCCTGATCAAGGCCGTTCCGGTTAATGCAGGGGAATAA

Upstream 100 bases:

>100_bases
CTCATCGTTATAGATTCATTTAGTTCTATGAATATGAGCGGTAATCAGGTCATAACCTTATTGTGGTTTTCAGATTGTAT
AAGGATAATTATTCAATATA

Downstream 100 bases:

>100_bases
CATGACCACCGTATTCAAGCTTCGCCTGTTAAATGGTGATCTCAATGGTCGTGAGCTGATATTACCGGAAGGTGAATTTA
CACTGGGGGAGCAGGGGTGT

Product: type III secretion protein EscC/SpiA, outer membrane pore

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MIVGLRQKPYLNLRNYKWMSLIYIMRKITGLILLFFATLLPYGKFSYGKAIPWQGEPFFIYSRGMTVSELLKDLGMNYGI
PVVISSEINEHFTGKIRDKTPEKILSELAGRYNITWYYDGETLYFYPVQSIKREFISPDGLAANTLVKYLQRGDVLAGKN
CAIKAIPHLDTLEVKGVPICIERVKSVSKMLSEQVRHQNQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELN
QGNNLPLAGGNQPDGNQASSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEISVTIIDVDAGDISQLGVDWS
ASASIGGTGVSFNSTFAKNNAEGFSTVIGDTGNFMVRLNALQKNSRARILSQPSVVTLNNIQAVLDKNVTFYTKLQGEKV
AKLESVTSGSLLRVTPRMIETEGVQEVLLNLNIQDGQQQASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIE
SQNKIPLLGDIPLLGGLFRSTDKQSHSVVRLFLIKAVPVNAGE

Sequences:

>Translated_523_residues
MIVGLRQKPYLNLRNYKWMSLIYIMRKITGLILLFFATLLPYGKFSYGKAIPWQGEPFFIYSRGMTVSELLKDLGMNYGI
PVVISSEINEHFTGKIRDKTPEKILSELAGRYNITWYYDGETLYFYPVQSIKREFISPDGLAANTLVKYLQRGDVLAGKN
CAIKAIPHLDTLEVKGVPICIERVKSVSKMLSEQVRHQNQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELN
QGNNLPLAGGNQPDGNQASSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEISVTIIDVDAGDISQLGVDWS
ASASIGGTGVSFNSTFAKNNAEGFSTVIGDTGNFMVRLNALQKNSRARILSQPSVVTLNNIQAVLDKNVTFYTKLQGEKV
AKLESVTSGSLLRVTPRMIETEGVQEVLLNLNIQDGQQQASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIE
SQNKIPLLGDIPLLGGLFRSTDKQSHSVVRLFLIKAVPVNAGE
>Mature_523_residues
MIVGLRQKPYLNLRNYKWMSLIYIMRKITGLILLFFATLLPYGKFSYGKAIPWQGEPFFIYSRGMTVSELLKDLGMNYGI
PVVISSEINEHFTGKIRDKTPEKILSELAGRYNITWYYDGETLYFYPVQSIKREFISPDGLAANTLVKYLQRGDVLAGKN
CAIKAIPHLDTLEVKGVPICIERVKSVSKMLSEQVRHQNQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELN
QGNNLPLAGGNQPDGNQASSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEISVTIIDVDAGDISQLGVDWS
ASASIGGTGVSFNSTFAKNNAEGFSTVIGDTGNFMVRLNALQKNSRARILSQPSVVTLNNIQAVLDKNVTFYTKLQGEKV
AKLESVTSGSLLRVTPRMIETEGVQEVLLNLNIQDGQQQASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIE
SQNKIPLLGDIPLLGGLFRSTDKQSHSVVRLFLIKAVPVNAGE

Specific function: Very likely required for the export process of the yop proteins [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI87082242, Length=410, Percent_Identity=27.3170731707317, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1789793, Length=252, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR003522 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 57975; Mature: 57975

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGLRQKPYLNLRNYKWMSLIYIMRKITGLILLFFATLLPYGKFSYGKAIPWQGEPFFI
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEE
YSRGMTVSELLKDLGMNYGIPVVISSEINEHFTGKIRDKTPEKILSELAGRYNITWYYDG
EECCCCHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECC
ETLYFYPVQSIKREFISPDGLAANTLVKYLQRGDVLAGKNCAIKAIPHLDTLEVKGVPIC
CEEEEEEHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCEEEECCCCCEEEECCCHHH
IERVKSVSKMLSEQVRHQNQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELN
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHC
QGNNLPLAGGNQPDGNQASSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEE
SVTIIDVDAGDISQLGVDWSASASIGGTGVSFNSTFAKNNAEGFSTVIGDTGNFMVRLNA
EEEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCEEEEEEE
LQKNSRARILSQPSVVTLNNIQAVLDKNVTFYTKLQGEKVAKLESVTSGSLLRVTPRMIE
CCCCCCCEEECCCCEEEECCHHHHHCCCCEEEEEECCCHHHHHHHCCCCCEEEECHHHHH
TEGVQEVLLNLNIQDGQQQASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIE
HCCHHHHHHCCCCCCCHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCEECCEEC
SQNKIPLLGDIPLLGGLFRSTDKQSHSVVRLFLIKAVPVNAGE
CCCCCCEEECCHHHHHHHHCCCCHHHHHEEEEEEEEECCCCCC
>Mature Secondary Structure
MIVGLRQKPYLNLRNYKWMSLIYIMRKITGLILLFFATLLPYGKFSYGKAIPWQGEPFFI
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEE
YSRGMTVSELLKDLGMNYGIPVVISSEINEHFTGKIRDKTPEKILSELAGRYNITWYYDG
EECCCCHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECC
ETLYFYPVQSIKREFISPDGLAANTLVKYLQRGDVLAGKNCAIKAIPHLDTLEVKGVPIC
CEEEEEEHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCEEEECCCCCEEEECCCHHH
IERVKSVSKMLSEQVRHQNQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELN
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHC
QGNNLPLAGGNQPDGNQASSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEE
SVTIIDVDAGDISQLGVDWSASASIGGTGVSFNSTFAKNNAEGFSTVIGDTGNFMVRLNA
EEEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCEEEEEEE
LQKNSRARILSQPSVVTLNNIQAVLDKNVTFYTKLQGEKVAKLESVTSGSLLRVTPRMIE
CCCCCCCEEECCCCEEEECCHHHHHCCCCEEEEEECCCHHHHHHHCCCCCEEEECHHHHH
TEGVQEVLLNLNIQDGQQQASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIE
HCCHHHHHHCCCCCCCHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCEECCEEC
SQNKIPLLGDIPLLGGLFRSTDKQSHSVVRLFLIKAVPVNAGE
CCCCCCEEECCHHHHHHHHCCCCHHHHHEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1860816 [H]