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The map label for this gene is ftsY

Identifier: 51594576

GI number: 51594576

Start: 263262

End: 264986

Strand: Direct

Name: ftsY

Synonym: YPTB0221

Alternate gene names: 51594576

Gene position: 263262-264986 (Clockwise)

Preceding gene: 51594573

Following gene: 51594577

Centisome position: 5.55

GC content: 47.48

Gene sequence:

>1725_bases
ATGGCAAAAGAAAAAAAACGTGGATTTTTTTCCTGGCTGGGTCTTGGCCGTCAGAGTGAAGAACCAGCAGCAGAGCCGCT
GGCGACTGAAAAAGAAGGCGTTACAGAGCAAGAAGACGTTATTGAACAAACCGGCGTTATTGAGCCAACAGACGTTATTG
AGCAAACCGTTGAGCACGTCATTAGTGAAAAAACGACTGAAGCTCCCGCGGAGAATGCCTTTATTGAGGTAGAACTGCGC
GAGCAGGTCGCTGCGGTAATTCCTACTGAGCCGAATAACGCCATAATGAGTGAGGGCGTCCCTGACACTTTACCAGAGAG
GGCGGTTGCCGAATCAGTAGTTGCCGAATTAGTAGAGACCGGTGACAACGCGGCCATTGTTCATGATGAGATTATCGAGC
CAATAACGCAGGTAACGGAAGCTGGCGGTGAGCTCTCTTTAGTAAAACCTGGCATCGAGGGTGATACCACTGAACAGGGC
GGCCCCACAGACAATCTGCCAAAACGGTCGTTAACGGAAGACAACCTTATTATTGATGTTCCCACCCCGCAGGCGGTGGT
AGAAGAATCGCGGGTTGACGCTGTTGAGCAACCTACCGAAACTTCTGAAGTTGAAGAAGTTGAAGAAGTTGAAGAAGTTG
AAGAAGTTGAAGAAGTTGAAGAAGTTGAAGAAGTTGAAGAAGTTGAAGAAGTTGAAGAAGTTGAAGAAGTTGAAGAAGTT
GAAGAAGTTGAAGAAGTTGAAGAAGTTGAAGAAGTTGAAGAAAAAATTATCCCGGTAGCGGCTCAAGAACAAGAGCGGCC
AACCAAAGAAGGTTTCTTCGCGCGTTTAAAACGCAGCTTAATCAAGACTAAACAGAATCTTGGCTCCGGTTTTATGGGGC
TGTTCAGCGGCAAAAAGATTGACGATGACTTGTTTGAAGAGCTGGAAGAACAGCTCCTGATCGCCGATGTTGGTGTCGAA
ACAACCCGTAAAATTATTACTTCTCTGACAGAACATGCCAGCCGTAAGCAGTTAAAAGATGCTGATGCGCTGTACGGCAA
GCTCAAAGAGGAAATGTCTGAGATTCTGTCTAAAGTTGACAAGCCATTAGATGTTAGCGGCAAGAGTCCGTATGTCATTT
TAATGGTTGGCGTTAATGGTGTGGGCAAAACCACCACTATTGGCAAACTGGCGCGCCAATTCCAGGCTGAAGGTAAATCT
GTCATGTTGGCGGCGGGTGATACATTCCGTGCCGCTGCCGTTGAGCAATTACAAGTTTGGGGTGAGCGTAACAAGATTGC
GGTTGTTGCACAGCATACCGGTGCAGATTCCGCTTCGGTTATTTTCGATGCGATTCAGGCGGCTAAAGCCCGTGGTATTG
ATGTGCTGTTGGCCGATACCGCTGGGCGTTTACAAAATAAAGCCCACTTGATGGAAGAGCTGAAGAAGATTGTCCGGGTA
ATGAAAAAACTGGACGGCGACGCCCCCCATGAGGTTATGCTGACACTGGATGCCAGTACCGGACAAAATGCGGTGAGTCA
GGCAAAACTGTTTAATGAAGCAGTGGGCCTAACCGGGATTACCCTAACTAAACTGGATGGTACCGCCAAAGGCGGGGTGA
TTTTTGCCATTGCTGATCAGTTTGAGATCCCAATCCGTTATATCGGTGTCGGAGAAGGTATAGAAGATTTGCGGCCATTT
AAGGCTGACGAATTTATTGAGGCTCTTTTTGCCCGAGAGGATTAA

Upstream 100 bases:

>100_bases
CAGGAGAAAGTGATAGACTTGCACATTATTATTGTACCCAAGGCTATTATTGTACCCAAAGGTATAAGCCATGATTTAAC
CGCGAGGAGTGTAGTCGCAA

Downstream 100 bases:

>100_bases
TACGGATGATTCGCTTTGAACAGGTCAGTAAAGCTTATCTGGGGGGACGGCAGGCGCTGCAGGGGGTCGATTTTCATCTG
CGTCCTGCGGAAATGGCGTT

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MAKEKKRGFFSWLGLGRQSEEPAAEPLATEKEGVTEQEDVIEQTGVIEPTDVIEQTVEHVISEKTTEAPAENAFIEVELR
EQVAAVIPTEPNNAIMSEGVPDTLPERAVAESVVAELVETGDNAAIVHDEIIEPITQVTEAGGELSLVKPGIEGDTTEQG
GPTDNLPKRSLTEDNLIIDVPTPQAVVEESRVDAVEQPTETSEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEV
EEVEEVEEVEEVEEKIIPVAAQEQERPTKEGFFARLKRSLIKTKQNLGSGFMGLFSGKKIDDDLFEELEEQLLIADVGVE
TTRKIITSLTEHASRKQLKDADALYGKLKEEMSEILSKVDKPLDVSGKSPYVILMVGVNGVGKTTTIGKLARQFQAEGKS
VMLAAGDTFRAAAVEQLQVWGERNKIAVVAQHTGADSASVIFDAIQAAKARGIDVLLADTAGRLQNKAHLMEELKKIVRV
MKKLDGDAPHEVMLTLDASTGQNAVSQAKLFNEAVGLTGITLTKLDGTAKGGVIFAIADQFEIPIRYIGVGEGIEDLRPF
KADEFIEALFARED

Sequences:

>Translated_574_residues
MAKEKKRGFFSWLGLGRQSEEPAAEPLATEKEGVTEQEDVIEQTGVIEPTDVIEQTVEHVISEKTTEAPAENAFIEVELR
EQVAAVIPTEPNNAIMSEGVPDTLPERAVAESVVAELVETGDNAAIVHDEIIEPITQVTEAGGELSLVKPGIEGDTTEQG
GPTDNLPKRSLTEDNLIIDVPTPQAVVEESRVDAVEQPTETSEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEV
EEVEEVEEVEEVEEKIIPVAAQEQERPTKEGFFARLKRSLIKTKQNLGSGFMGLFSGKKIDDDLFEELEEQLLIADVGVE
TTRKIITSLTEHASRKQLKDADALYGKLKEEMSEILSKVDKPLDVSGKSPYVILMVGVNGVGKTTTIGKLARQFQAEGKS
VMLAAGDTFRAAAVEQLQVWGERNKIAVVAQHTGADSASVIFDAIQAAKARGIDVLLADTAGRLQNKAHLMEELKKIVRV
MKKLDGDAPHEVMLTLDASTGQNAVSQAKLFNEAVGLTGITLTKLDGTAKGGVIFAIADQFEIPIRYIGVGEGIEDLRPF
KADEFIEALFARED
>Mature_573_residues
AKEKKRGFFSWLGLGRQSEEPAAEPLATEKEGVTEQEDVIEQTGVIEPTDVIEQTVEHVISEKTTEAPAENAFIEVELRE
QVAAVIPTEPNNAIMSEGVPDTLPERAVAESVVAELVETGDNAAIVHDEIIEPITQVTEAGGELSLVKPGIEGDTTEQGG
PTDNLPKRSLTEDNLIIDVPTPQAVVEESRVDAVEQPTETSEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVE
EVEEVEEVEEVEEKIIPVAAQEQERPTKEGFFARLKRSLIKTKQNLGSGFMGLFSGKKIDDDLFEELEEQLLIADVGVET
TRKIITSLTEHASRKQLKDADALYGKLKEEMSEILSKVDKPLDVSGKSPYVILMVGVNGVGKTTTIGKLARQFQAEGKSV
MLAAGDTFRAAAVEQLQVWGERNKIAVVAQHTGADSASVIFDAIQAAKARGIDVLLADTAGRLQNKAHLMEELKKIVRVM
KKLDGDAPHEVMLTLDASTGQNAVSQAKLFNEAVGLTGITLTKLDGTAKGGVIFAIADQFEIPIRYIGVGEGIEDLRPFK
ADEFIEALFARED

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=203, Percent_Identity=34.4827586206897, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI4507215, Length=203, Percent_Identity=34.4827586206897, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI295424842, Length=330, Percent_Identity=29.0909090909091, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI23308697, Length=330, Percent_Identity=29.0909090909091, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI89061728, Length=147, Percent_Identity=30.6122448979592, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789874, Length=322, Percent_Identity=86.6459627329193, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI1788963, Length=311, Percent_Identity=32.475884244373, Blast_Score=152, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI193206261, Length=312, Percent_Identity=32.0512820512821, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17539958, Length=229, Percent_Identity=30.5676855895196, Blast_Score=119, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=203, Percent_Identity=36.9458128078818, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320498, Length=250, Percent_Identity=32.8, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17647949, Length=284, Percent_Identity=30.9859154929577, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24641198, Length=325, Percent_Identity=29.5384615384615, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 62659; Mature: 62528

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEKKRGFFSWLGLGRQSEEPAAEPLATEKEGVTEQEDVIEQTGVIEPTDVIEQTVEHV
CCCCHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHH
ISEKTTEAPAENAFIEVELREQVAAVIPTEPNNAIMSEGVPDTLPERAVAESVVAELVET
HHHCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHC
GDNAAIVHDEIIEPITQVTEAGGELSLVKPGIEGDTTEQGGPTDNLPKRSLTEDNLIIDV
CCCCEEEHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
PTPQAVVEESRVDAVEQPTETSEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEV
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEVEEVEEVEEVEEKIIPVAAQEQERPTKEGFFARLKRSLIKTKQNLGSGFMGLFSGKKI
HHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
DDDLFEELEEQLLIADVGVETTRKIITSLTEHASRKQLKDADALYGKLKEEMSEILSKVD
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPLDVSGKSPYVILMVGVNGVGKTTTIGKLARQFQAEGKSVMLAAGDTFRAAAVEQLQVW
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
GERNKIAVVAQHTGADSASVIFDAIQAAKARGIDVLLADTAGRLQNKAHLMEELKKIVRV
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
MKKLDGDAPHEVMLTLDASTGQNAVSQAKLFNEAVGLTGITLTKLDGTAKGGVIFAIADQ
HHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECC
FEIPIRYIGVGEGIEDLRPFKADEFIEALFARED
CCCCEEEEECCCCHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AKEKKRGFFSWLGLGRQSEEPAAEPLATEKEGVTEQEDVIEQTGVIEPTDVIEQTVEHV
CCCHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHH
ISEKTTEAPAENAFIEVELREQVAAVIPTEPNNAIMSEGVPDTLPERAVAESVVAELVET
HHHCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHC
GDNAAIVHDEIIEPITQVTEAGGELSLVKPGIEGDTTEQGGPTDNLPKRSLTEDNLIIDV
CCCCEEEHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
PTPQAVVEESRVDAVEQPTETSEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEVEEV
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEVEEVEEVEEVEEKIIPVAAQEQERPTKEGFFARLKRSLIKTKQNLGSGFMGLFSGKKI
HHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
DDDLFEELEEQLLIADVGVETTRKIITSLTEHASRKQLKDADALYGKLKEEMSEILSKVD
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPLDVSGKSPYVILMVGVNGVGKTTTIGKLARQFQAEGKSVMLAAGDTFRAAAVEQLQVW
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
GERNKIAVVAQHTGADSASVIFDAIQAAKARGIDVLLADTAGRLQNKAHLMEELKKIVRV
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
MKKLDGDAPHEVMLTLDASTGQNAVSQAKLFNEAVGLTGITLTKLDGTAKGGVIFAIADQ
HHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECC
FEIPIRYIGVGEGIEDLRPFKADEFIEALFARED
CCCCEEEEECCCCHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]