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The map label for this gene is xerC

Identifier: 51594547

GI number: 51594547

Start: 230872

End: 231783

Strand: Direct

Name: xerC

Synonym: YPTB0192

Alternate gene names: 51594547

Gene position: 230872-231783 (Clockwise)

Preceding gene: 51594546

Following gene: 51594548

Centisome position: 4.87

GC content: 53.4

Gene sequence:

>912_bases
ATGACCGAGTTCAGTGCTTCACTGGCTCCGCAGGTAGAGGCTTTTCTCCGTTATCTCAGTATTGAGCGTCAGCTTAGTCC
ACTGACCGTCACCAGTTATCGCCGTCAGTTGTCTGCGCTAATGGAAATAGGCGAACAGATGGGCTTGGCTCACTGGCAGA
CGCTGGATGCTGCTCAGGTCCGTTCGTTGGTCTCCCGCAGCAAACGTACGGGTTTACATGCTTCAAGCCTGGCATTACGG
CTCTCCGCATTACGCAGTTTTCTCAACTGGTTGGTCAGCCAGGGCGTGCTGCCAGCCAACCCCGCTAAAGGGGTCAGTAC
GCCACGCTCGGGCCGCCACCTGCCAAAAAATATTGATGTTGATGAAATCAATAAACTGCTGAGTATTGATCTGAATGATC
CGCTGGCGGTACGTGACCGGGCCATGCTGGAGGTGATGTACGGCGCGGGGCTGCGTTTATCTGAATTGGTTGGCATGAAC
TGTAAACATGTGGATCTGGCGAGCGGCGATGTCTGGGTGATGGGGAAGGGCAGTAAAGAGCGCAAGGTGCCGTTAGGTAA
AACGGCGGTGACCTGGTTACAGCATTGGCTGGCGTTACGTGAGTTATTCGAACCGCAAGATGACGCTATTTTTCTGGCCA
ATACCGGCAAGCGTATTTCAGCCCGTAATGTGCAGAAGCGCTTTGCCGAATGGGGGGTGAAGCAGGGGGTCAGTAGCCAC
ATTCACCCACATAAATTACGTCACTCTTTTGCCACGCACATGCTGGAATCCAGTGGTGATCTACGCGCAGTACAAGAGCT
ACTGGGCCATGCCAACCTGACCACCACGCAAATTTATACACATCTCGACTTTCAACATCTGGCGACAGTGTATGATGCTG
CTCATCCACGGGCCAAACGAGGCAAATCCTGA

Upstream 100 bases:

>100_bases
GCCGCGATGCTCAGCATTATCAACAAGGTATGGGGACGGTGATGTTAAACCAGCTATCCACATTGCTTCCGGGCCTCCTG
GCACGTTGGATCGAGCCGGT

Downstream 100 bases:

>100_bases
TGCATTTTTATCGTCCACTTGAGCGTATTTCCGCTATTACCTTCGATTTGGATGACACGTTGTACGACAATCGGCCAGTG
ATCGCGCGGACTGAACAGCA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTEFSASLAPQVEAFLRYLSIERQLSPLTVTSYRRQLSALMEIGEQMGLAHWQTLDAAQVRSLVSRSKRTGLHASSLALR
LSALRSFLNWLVSQGVLPANPAKGVSTPRSGRHLPKNIDVDEINKLLSIDLNDPLAVRDRAMLEVMYGAGLRLSELVGMN
CKHVDLASGDVWVMGKGSKERKVPLGKTAVTWLQHWLALRELFEPQDDAIFLANTGKRISARNVQKRFAEWGVKQGVSSH
IHPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLATVYDAAHPRAKRGKS

Sequences:

>Translated_303_residues
MTEFSASLAPQVEAFLRYLSIERQLSPLTVTSYRRQLSALMEIGEQMGLAHWQTLDAAQVRSLVSRSKRTGLHASSLALR
LSALRSFLNWLVSQGVLPANPAKGVSTPRSGRHLPKNIDVDEINKLLSIDLNDPLAVRDRAMLEVMYGAGLRLSELVGMN
CKHVDLASGDVWVMGKGSKERKVPLGKTAVTWLQHWLALRELFEPQDDAIFLANTGKRISARNVQKRFAEWGVKQGVSSH
IHPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLATVYDAAHPRAKRGKS
>Mature_302_residues
TEFSASLAPQVEAFLRYLSIERQLSPLTVTSYRRQLSALMEIGEQMGLAHWQTLDAAQVRSLVSRSKRTGLHASSLALRL
SALRSFLNWLVSQGVLPANPAKGVSTPRSGRHLPKNIDVDEINKLLSIDLNDPLAVRDRAMLEVMYGAGLRLSELVGMNC
KHVDLASGDVWVMGKGSKERKVPLGKTAVTWLQHWLALRELFEPQDDAIFLANTGKRISARNVQKRFAEWGVKQGVSSHI
HPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLATVYDAAHPRAKRGKS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region, forming

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=72.6351351351351, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1789261, Length=299, Percent_Identity=38.4615384615385, Blast_Score=187, Evalue=6e-49,
Organism=Escherichia coli, GI1790768, Length=162, Percent_Identity=27.1604938271605, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790767, Length=181, Percent_Identity=27.6243093922652, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33775; Mature: 33644

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFSASLAPQVEAFLRYLSIERQLSPLTVTSYRRQLSALMEIGEQMGLAHWQTLDAAQV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHH
RSLVSRSKRTGLHASSLALRLSALRSFLNWLVSQGVLPANPAKGVSTPRSGRHLPKNIDV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
DEINKLLSIDLNDPLAVRDRAMLEVMYGAGLRLSELVGMNCKHVDLASGDVWVMGKGSKE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEECCCCEEEEECCCCC
RKVPLGKTAVTWLQHWLALRELFEPQDDAIFLANTGKRISARNVQKRFAEWGVKQGVSSH
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
IHPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLATVYDAAHPRAKR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCC
GKS
CCC
>Mature Secondary Structure 
TEFSASLAPQVEAFLRYLSIERQLSPLTVTSYRRQLSALMEIGEQMGLAHWQTLDAAQV
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHH
RSLVSRSKRTGLHASSLALRLSALRSFLNWLVSQGVLPANPAKGVSTPRSGRHLPKNIDV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
DEINKLLSIDLNDPLAVRDRAMLEVMYGAGLRLSELVGMNCKHVDLASGDVWVMGKGSKE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEECCCCEEEEECCCCC
RKVPLGKTAVTWLQHWLALRELFEPQDDAIFLANTGKRISARNVQKRFAEWGVKQGVSSH
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
IHPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLATVYDAAHPRAKR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCC
GKS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]