Click here to switch to the map view.

The map label for this gene is oxyR

Identifier: 51594478

GI number: 51594478

Start: 142377

End: 143294

Strand: Direct

Name: oxyR

Synonym: YPTB0120

Alternate gene names: 51594478

Gene position: 142377-143294 (Clockwise)

Preceding gene: 51594475

Following gene: 51594480

Centisome position: 3.0

GC content: 48.69

Gene sequence:

>918_bases
ATGAATATTCGTGATCTAGAGTACTTAGTGGCGTTGGCTGAATTTAGGCACTTCCGGCGTGCCGCCGACTCCTGTCATGT
CAGCCAACCCACATTAAGCGGTCAGATTCGTAAACTGGAAGATGAGTTGGGGATCATGTTGTTGGAGCGAACTAGTCGTA
AGGTGTTGTTTACACAGGCTGGTTTACTGTTGGTGGAGCAGGCGAAAACGGTATTACGGGAAGTGAAAGTACTGAAAGAG
ATGGCCAGTTTACAGGGTGAAAGTATGTCTGGGCCGTTGCATATTGGGCTTATTCCTACCGTTGGGCCTTATCTGTTACC
ACAAATTATTCCTATGCTGCATAAAACATTCCCCAAATTGGAAATGTATCTGCATGAAGCCCAGACCCAAAATCTCTTAG
CCCAGTTGGATAGTGGTAAATTGGATTGTGCCATTTTAGCCCTGGTCAAAGAGACCGAAGCTTTTATCGAAATTCCGTTA
TTTGACGAGCCGATGAATCTAGCCATTTATGCCGATCATCCGTGGGCGAACCGCGAAAGAGTGGAGATGCATGAATTGGC
GGGAGAGAAGTTACTGATGCTGGAAGATGGTCATTGTTTACGTGATCAGGCGATGGGCTTTTGCTTCCAGGCTGGAGCGG
ATGAAGATACTCACTTCCGGGCGACTAGCTTGGAAACCCTGCGCAACATGGTCGCAGCGGGTAGTGGTATTACGCTGTTG
CCAGCACTGGCTGTGCCGAATGAAAGACAGCGCGATGGTGTATGTTATCTGGAGTGCTACAAACCTGTCCCTAAACGCAC
CATTGCGTTGGTGTATCGCCCCGGTTCTCCATTGCGTGGCCGCTATGAACAACTTGCCGAGGCAATACGTGATCACATGC
AAGAGCGCATGGCCTCATCATTAGAACAGGCGATTTAA

Upstream 100 bases:

>100_bases
GTCTCTTTGTTGGGTCATATTATTAATTTTATCTCTTGATAGTTCTAATCACTGGTTGCTATCTTATCTATCGTCAGTAG
CTATCATAAGGTGGGCATAG

Downstream 100 bases:

>100_bases
GCCATTGAGTGCGGCCACACGGTAGGCTTCTGCCATGGTTGGGTAGTTGAAGGTAGTATTAACGAAATACTCGAGCGTAT
TGCCTTCTCCTTTCTGTTCC

Product: DNA-binding transcriptional regulator OxyR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNIRDLEYLVALAEFRHFRRAADSCHVSQPTLSGQIRKLEDELGIMLLERTSRKVLFTQAGLLLVEQAKTVLREVKVLKE
MASLQGESMSGPLHIGLIPTVGPYLLPQIIPMLHKTFPKLEMYLHEAQTQNLLAQLDSGKLDCAILALVKETEAFIEIPL
FDEPMNLAIYADHPWANRERVEMHELAGEKLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLL
PALAVPNERQRDGVCYLECYKPVPKRTIALVYRPGSPLRGRYEQLAEAIRDHMQERMASSLEQAI

Sequences:

>Translated_305_residues
MNIRDLEYLVALAEFRHFRRAADSCHVSQPTLSGQIRKLEDELGIMLLERTSRKVLFTQAGLLLVEQAKTVLREVKVLKE
MASLQGESMSGPLHIGLIPTVGPYLLPQIIPMLHKTFPKLEMYLHEAQTQNLLAQLDSGKLDCAILALVKETEAFIEIPL
FDEPMNLAIYADHPWANRERVEMHELAGEKLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLL
PALAVPNERQRDGVCYLECYKPVPKRTIALVYRPGSPLRGRYEQLAEAIRDHMQERMASSLEQAI
>Mature_305_residues
MNIRDLEYLVALAEFRHFRRAADSCHVSQPTLSGQIRKLEDELGIMLLERTSRKVLFTQAGLLLVEQAKTVLREVKVLKE
MASLQGESMSGPLHIGLIPTVGPYLLPQIIPMLHKTFPKLEMYLHEAQTQNLLAQLDSGKLDCAILALVKETEAFIEIPL
FDEPMNLAIYADHPWANRERVEMHELAGEKLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLL
PALAVPNERQRDGVCYLECYKPVPKRTIALVYRPGSPLRGRYEQLAEAIRDHMQERMASSLEQAI

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=305, Percent_Identity=86.5573770491803, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI157672245, Length=273, Percent_Identity=30.7692307692308, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788887, Length=312, Percent_Identity=28.8461538461538, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI145693105, Length=285, Percent_Identity=28.7719298245614, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787879, Length=248, Percent_Identity=31.4516129032258, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788748, Length=298, Percent_Identity=27.1812080536913, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787530, Length=248, Percent_Identity=25.8064516129032, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790208, Length=265, Percent_Identity=30.188679245283, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788297, Length=251, Percent_Identity=27.8884462151394, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367136, Length=243, Percent_Identity=26.3374485596708, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788296, Length=222, Percent_Identity=26.5765765765766, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790262, Length=251, Percent_Identity=28.2868525896414, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789506, Length=225, Percent_Identity=23.5555555555556, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788626, Length=291, Percent_Identity=24.7422680412371, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=282, Percent_Identity=22.6950354609929, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994962, Length=266, Percent_Identity=27.4436090225564, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI145693193, Length=160, Percent_Identity=29.375, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34375; Mature: 34375

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRDLEYLVALAEFRHFRRAADSCHVSQPTLSGQIRKLEDELGIMLLERTSRKVLFTQA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCEEEEECCCCEEEEHHH
GLLLVEQAKTVLREVKVLKEMASLQGESMSGPLHIGLIPTVGPYLLPQIIPMLHKTFPKL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
EMYLHEAQTQNLLAQLDSGKLDCAILALVKETEAFIEIPLFDEPMNLAIYADHPWANRER
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHEEECCCCCCCCCEEEEECCCCCCCHH
VEMHELAGEKLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLL
HHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
PALAVPNERQRDGVCYLECYKPVPKRTIALVYRPGSPLRGRYEQLAEAIRDHMQERMASS
EEECCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEQAI
HHHCC
>Mature Secondary Structure
MNIRDLEYLVALAEFRHFRRAADSCHVSQPTLSGQIRKLEDELGIMLLERTSRKVLFTQA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCEEEEECCCCEEEEHHH
GLLLVEQAKTVLREVKVLKEMASLQGESMSGPLHIGLIPTVGPYLLPQIIPMLHKTFPKL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
EMYLHEAQTQNLLAQLDSGKLDCAILALVKETEAFIEIPLFDEPMNLAIYADHPWANRER
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHEEECCCCCCCCCEEEEECCCCCCCHH
VEMHELAGEKLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLL
HHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
PALAVPNERQRDGVCYLECYKPVPKRTIALVYRPGSPLRGRYEQLAEAIRDHMQERMASS
EEECCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEQAI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA