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The map label for this gene is qor [H]

Identifier: 50843635

GI number: 50843635

Start: 2380556

End: 2381557

Strand: Direct

Name: qor [H]

Synonym: PPA2200

Alternate gene names: 50843635

Gene position: 2380556-2381557 (Clockwise)

Preceding gene: 50843631

Following gene: 50843636

Centisome position: 92.98

GC content: 62.38

Gene sequence:

>1002_bases
ATGCATGCGATCACCGTCCGCCCGACCGACAAGACAGACTCCAAGGGGCGCCATCGTCCCGGCCCTGAATGCATTGAATG
GACCGAGGTCCCCACACCGAAACCTGGCCCTGGGGAAGTCCTCGTCAAGGTGAAGGCGGCCGGCATTAACCGCGGCGACC
TGCTGCAGCGCCAAGGCCTCTACCCGCCGCCGAAGGGCGTCTCGGAAACCATGGGCCTGGAGGTTACCGGCGTCATTTCC
TCCCTCGGTCAAGACGTCACAGGCTGGTCCGAGGATGATGAGGTCATTGCGCTGCTAGCCGGCGGTGGTTACGCCGAGTA
CGTCATCGTCCCGGCAGGCCAACTCCTGCCCATCCCTGAGGGCATCGACCCGGTAACCGCGTCAACACTCATTGAGGTTA
CTGCCACTGTCATCTCCAACATGGACCACGTCGGCCTAGCCAGGGGTGAAACCTTCCTCGTGCACGGCGGCGCCGGCGGC
ATCGGCCAGTTCGCTATCCAATACGCCAAGTCGCTCGAATGCACGGTCATCACCACCTGTGGCACCGCCGAGAAGCAGGA
GTTCTGCCGCACTCTCGGTGCCGACGTCGCCCTCGACTATCACGAGGACTGGGTTGCCGGCGTCAAAGACGCTACGGGGG
GTCGTGGTGCCGACGTCATCCTCGACGTCATGGGCGCTAAGTACCTCGACCTCAACGTCGATGCTCTCGCTATTGGCGGG
CGTCTCGACATCATTGGAATGCAGGGCGGCATCAAGGGAGAGCTCAATATTGCAAAGCTTCTCAACAAGCGCGCCCTCGT
CACCGCTACTAGCCTGCGGCCTCGCCCCCTTGAAGAAAAAGCCAAGATTTGCCAGCGGGTCCGTGAGGTTGCATGGCCGC
TCTACACCAATGGCAGCATCAAACCCGCCCCAGTTGAGTCCTTCCCCATGTCCGAGGCAGGCAGGGCCCACGAACGGCTC
GAATCCGGTGAGGTGCTCGGCAAGGTTGCACTGACCCTCTGA

Upstream 100 bases:

>100_bases
CTCATGTGTGGCATCTGTGGATAACGCCAGGAAACTGGGAAAACTTCGTCTGCGAGCGTGAAGGATTTGGGAGCGCTCAC
CCCTGTGGCAGGCTTAACAC

Downstream 100 bases:

>100_bases
CGCCCTAAAACCCACAACGACCTGTCATGGCTGGCCCATGGCAGGTCGTTTTATGTTCTAGGCGTAGCCCCGATAGCTTC
CCGGTCCAGCTATTCGCATC

Product: Zn-binding dehydrogenase/oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MHAITVRPTDKTDSKGRHRPGPECIEWTEVPTPKPGPGEVLVKVKAAGINRGDLLQRQGLYPPPKGVSETMGLEVTGVIS
SLGQDVTGWSEDDEVIALLAGGGYAEYVIVPAGQLLPIPEGIDPVTASTLIEVTATVISNMDHVGLARGETFLVHGGAGG
IGQFAIQYAKSLECTVITTCGTAEKQEFCRTLGADVALDYHEDWVAGVKDATGGRGADVILDVMGAKYLDLNVDALAIGG
RLDIIGMQGGIKGELNIAKLLNKRALVTATSLRPRPLEEKAKICQRVREVAWPLYTNGSIKPAPVESFPMSEAGRAHERL
ESGEVLGKVALTL

Sequences:

>Translated_333_residues
MHAITVRPTDKTDSKGRHRPGPECIEWTEVPTPKPGPGEVLVKVKAAGINRGDLLQRQGLYPPPKGVSETMGLEVTGVIS
SLGQDVTGWSEDDEVIALLAGGGYAEYVIVPAGQLLPIPEGIDPVTASTLIEVTATVISNMDHVGLARGETFLVHGGAGG
IGQFAIQYAKSLECTVITTCGTAEKQEFCRTLGADVALDYHEDWVAGVKDATGGRGADVILDVMGAKYLDLNVDALAIGG
RLDIIGMQGGIKGELNIAKLLNKRALVTATSLRPRPLEEKAKICQRVREVAWPLYTNGSIKPAPVESFPMSEAGRAHERL
ESGEVLGKVALTL
>Mature_333_residues
MHAITVRPTDKTDSKGRHRPGPECIEWTEVPTPKPGPGEVLVKVKAAGINRGDLLQRQGLYPPPKGVSETMGLEVTGVIS
SLGQDVTGWSEDDEVIALLAGGGYAEYVIVPAGQLLPIPEGIDPVTASTLIEVTATVISNMDHVGLARGETFLVHGGAGG
IGQFAIQYAKSLECTVITTCGTAEKQEFCRTLGADVALDYHEDWVAGVKDATGGRGADVILDVMGAKYLDLNVDALAIGG
RLDIIGMQGGIKGELNIAKLLNKRALVTATSLRPRPLEEKAKICQRVREVAWPLYTNGSIKPAPVESFPMSEAGRAHERL
ESGEVLGKVALTL

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=322, Percent_Identity=37.5776397515528, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI22538444, Length=322, Percent_Identity=37.5776397515528, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI28557745, Length=248, Percent_Identity=34.6774193548387, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI194239674, Length=321, Percent_Identity=27.7258566978193, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI13236495, Length=321, Percent_Identity=27.7258566978193, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI18379349, Length=310, Percent_Identity=27.0967741935484, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI194239676, Length=320, Percent_Identity=25.3125, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI24308257, Length=318, Percent_Identity=24.8427672955975, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI47519420, Length=340, Percent_Identity=27.6470588235294, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41872631, Length=228, Percent_Identity=30.7017543859649, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI197927207, Length=190, Percent_Identity=28.4210526315789, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1790485, Length=309, Percent_Identity=32.0388349514563, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI226510992, Length=294, Percent_Identity=26.530612244898, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=232, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=200, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212642053, Length=332, Percent_Identity=27.1084337349398, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=334, Percent_Identity=24.8502994011976, Blast_Score=99, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6324486, Length=334, Percent_Identity=24.8502994011976, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323729, Length=338, Percent_Identity=23.0769230769231, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6319520, Length=326, Percent_Identity=23.9263803680982, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19920632, Length=264, Percent_Identity=28.030303030303, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI221330659, Length=264, Percent_Identity=28.030303030303, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24581345, Length=247, Percent_Identity=25.9109311740891, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35234; Mature: 35234

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAITVRPTDKTDSKGRHRPGPECIEWTEVPTPKPGPGEVLVKVKAAGINRGDLLQRQGL
CCEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCC
YPPPKGVSETMGLEVTGVISSLGQDVTGWSEDDEVIALLAGGGYAEYVIVPAGQLLPIPE
CCCCCCCHHHHCEEHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCEEECCC
GIDPVTASTLIEVTATVISNMDHVGLARGETFLVHGGAGGIGQFAIQYAKSLECTVITTC
CCCCHHHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEC
GTAEKQEFCRTLGADVALDYHEDWVAGVKDATGGRGADVILDVMGAKYLDLNVDALAIGG
CCHHHHHHHHHHCCCEEEECCHHHHHCCCCCCCCCCHHHHHHHHCCEEEECCCEEEEECC
RLDIIGMQGGIKGELNIAKLLNKRALVTATSLRPRPLEEKAKICQRVREVAWPLYTNGSI
EEEEEEECCCCCCCCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEECCCC
KPAPVESFPMSEAGRAHERLESGEVLGKVALTL
CCCCCCCCCCHHCCHHHHHHHCCHHEEEEEECC
>Mature Secondary Structure
MHAITVRPTDKTDSKGRHRPGPECIEWTEVPTPKPGPGEVLVKVKAAGINRGDLLQRQGL
CCEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCC
YPPPKGVSETMGLEVTGVISSLGQDVTGWSEDDEVIALLAGGGYAEYVIVPAGQLLPIPE
CCCCCCCHHHHCEEHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCEEECCC
GIDPVTASTLIEVTATVISNMDHVGLARGETFLVHGGAGGIGQFAIQYAKSLECTVITTC
CCCCHHHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEC
GTAEKQEFCRTLGADVALDYHEDWVAGVKDATGGRGADVILDVMGAKYLDLNVDALAIGG
CCHHHHHHHHHHCCCEEEECCHHHHHCCCCCCCCCCHHHHHHHHCCEEEECCCEEEEECC
RLDIIGMQGGIKGELNIAKLLNKRALVTATSLRPRPLEEKAKICQRVREVAWPLYTNGSI
EEEEEEECCCCCCCCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEECCCC
KPAPVESFPMSEAGRAHERLESGEVLGKVALTL
CCCCCCCCCCHHCCHHHHHHHCCHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]