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The map label for this gene is tadA [H]

Identifier: 50843619

GI number: 50843619

Start: 2364248

End: 2364697

Strand: Reverse

Name: tadA [H]

Synonym: PPA2182

Alternate gene names: 50843619

Gene position: 2364697-2364248 (Counterclockwise)

Preceding gene: 50843620

Following gene: 50843618

Centisome position: 92.36

GC content: 64.67

Gene sequence:

>450_bases
ATGACCCAGGCCCTTGACGTGGCGCGCCGCGCCGCCACGTGGGGTGACGTTCCCATCGGCGCGGTGATTCTCGGCGCTAA
CGGCGAAGTCCTTTCCGAAGCCGGCAACGAACGGGAGCGCACCGGCGACCCGACGGCCCACGCGGAGGTGCTGGCCATCC
GTCGTGCTGCGGAAGCCCGTGACGGCTGGCGTCTCGGTGATTGCACCCTCGTCGTCACCTTGGAACCATGCACCATGTGC
GCCGGAACCATTGTTGCTGCGAGGATCCCGAGAGTGGTTTTTGGAGCCTTTGATCCGAAGGCCGGTGCCGTCAGTTCCCT
CTTCGATGCCATGCGCGATCCGAGGTTGCCACACCGGCCGAAAGTGGTCACAGGTGTGATGGCCGAGGAGTCGTCTGCTC
TGTTGCGCGAATTCTTTGACGGACATCGGGCCTGTACCGTGGACGGGTGA

Upstream 100 bases:

>100_bases
CATTGCTGCCCGGGTTCATTTCGGGCCGCAGTTCGAGCGGGCCGCTAACGCTTCGGCGCGCTGACCTGTGGCCGGTCCGG
TGCCGGGTTGGCGTCAGGCC

Downstream 100 bases:

>100_bases
CCAACACGACGACGGAACCGACACCCGCAAGATCCGGGGCGACACCAGAGCCCGGGGAGAAACGCGTCCGGTTCCCCCGT
ACTCGGGCATACATCCAGCG

Product: putative cytidine and deoxycytidylate deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MTQALDVARRAATWGDVPIGAVILGANGEVLSEAGNERERTGDPTAHAEVLAIRRAAEARDGWRLGDCTLVVTLEPCTMC
AGTIVAARIPRVVFGAFDPKAGAVSSLFDAMRDPRLPHRPKVVTGVMAEESSALLREFFDGHRACTVDG

Sequences:

>Translated_149_residues
MTQALDVARRAATWGDVPIGAVILGANGEVLSEAGNERERTGDPTAHAEVLAIRRAAEARDGWRLGDCTLVVTLEPCTMC
AGTIVAARIPRVVFGAFDPKAGAVSSLFDAMRDPRLPHRPKVVTGVMAEESSALLREFFDGHRACTVDG
>Mature_148_residues
TQALDVARRAATWGDVPIGAVILGANGEVLSEAGNERERTGDPTAHAEVLAIRRAAEARDGWRLGDCTLVVTLEPCTMCA
GTIVAARIPRVVFGAFDPKAGAVSSLFDAMRDPRLPHRPKVVTGVMAEESSALLREFFDGHRACTVDG

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=149, Percent_Identity=30.8724832214765, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI145693172, Length=139, Percent_Identity=46.7625899280576, Blast_Score=126, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17541138, Length=149, Percent_Identity=31.5436241610738, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=120, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17554608, Length=127, Percent_Identity=31.496062992126, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355527, Length=149, Percent_Identity=31.5436241610738, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15827; Mature: 15696

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQALDVARRAATWGDVPIGAVILGANGEVLSEAGNERERTGDPTAHAEVLAIRRAAEAR
CCHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHC
DGWRLGDCTLVVTLEPCTMCAGTIVAARIPRVVFGAFDPKAGAVSSLFDAMRDPRLPHRP
CCCEECCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCC
KVVTGVMAEESSALLREFFDGHRACTVDG
CEEEHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
TQALDVARRAATWGDVPIGAVILGANGEVLSEAGNERERTGDPTAHAEVLAIRRAAEAR
CHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHC
DGWRLGDCTLVVTLEPCTMCAGTIVAARIPRVVFGAFDPKAGAVSSLFDAMRDPRLPHRP
CCCEECCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCC
KVVTGVMAEESSALLREFFDGHRACTVDG
CEEEHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]