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The map label for this gene is yfkM [H]

Identifier: 50843589

GI number: 50843589

Start: 2335002

End: 2335670

Strand: Direct

Name: yfkM [H]

Synonym: PPA2151

Alternate gene names: 50843589

Gene position: 2335002-2335670 (Clockwise)

Preceding gene: 50843588

Following gene: 50843590

Centisome position: 91.2

GC content: 59.49

Gene sequence:

>669_bases
GTGATCTCACACTGTGGGCCCTGCCGCGGCAACAGTGTGGTGGCCGGGGAGGCTCCACTGTGCCGAAATCGGAATATTTC
AGCCTTTGGTCTTGTTCCACCACTGAAAGCGATTGAAGGAGGAACCACCGTGGCTGCACGCGCACTTATCGCCGTCACCG
ACTTCGGAGTCGAGGAGGCCGAGCTCGTCGAGCCCCTCAACGCCCTCAAGAAGGCCGGCATCGAGGTAACCGTCGCCTCC
AACAGCGGCGAGTCCATTCAAACCGTCACCGGCGACAAGGATTGGGCGTCCAAGGTGAACGCTGATTCCAGGCTTGCCGA
CGCCAAGGCTTCCGATTACGACTTGCTCGTCATCCCCGGTGGCACCGTCAATGCGGATACCTTGCGTATTGACGAGGACG
GACGCCGCCTGGTCAAGGAGTTCGCAACTGCTGGCAAGCCAGTCGGGGCTATCTGTCACGGACCGTGGGTACTGATTGAC
GCCGACGTTGCCAAAGGCAAGACGATGACCTCCTATATCTCCATTCGACCGGACCTTGAAAATGCCGGAGCTTCCTGGGT
AGACAAGGAACTTTTCCGTTGCCCCGGCAACGGCTGGGTACTACTTACCTCGCGCAACCCCAACGATCTACCCGCCTTCG
CTAAGGCTCTGGTCGACGAGATCTCCTGA

Upstream 100 bases:

>100_bases
ATCCTGTCACCCCGACCATCCATTCTTCAGTTGACAGATTTCGTCAGCTTTGGGGACTCACCCTGATCTTGTATCACCTC
TCAAGGGGCCTATTCTGGCC

Downstream 100 bases:

>100_bases
TTCACACAACTTCAGAAGAAAGGGACTCGCATCTGCAGGTGTGGGTCCCTTTGCGTATGTCCAAGGGCACGACGATCTGT
GTTCCGAAACCCCTAAAGCC

Product: putative intracellular protease / general stress protein 18

Products: NA

Alternate protein names: GSP18 [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MISHCGPCRGNSVVAGEAPLCRNRNISAFGLVPPLKAIEGGTTVAARALIAVTDFGVEEAELVEPLNALKKAGIEVTVAS
NSGESIQTVTGDKDWASKVNADSRLADAKASDYDLLVIPGGTVNADTLRIDEDGRRLVKEFATAGKPVGAICHGPWVLID
ADVAKGKTMTSYISIRPDLENAGASWVDKELFRCPGNGWVLLTSRNPNDLPAFAKALVDEIS

Sequences:

>Translated_222_residues
MISHCGPCRGNSVVAGEAPLCRNRNISAFGLVPPLKAIEGGTTVAARALIAVTDFGVEEAELVEPLNALKKAGIEVTVAS
NSGESIQTVTGDKDWASKVNADSRLADAKASDYDLLVIPGGTVNADTLRIDEDGRRLVKEFATAGKPVGAICHGPWVLID
ADVAKGKTMTSYISIRPDLENAGASWVDKELFRCPGNGWVLLTSRNPNDLPAFAKALVDEIS
>Mature_222_residues
MISHCGPCRGNSVVAGEAPLCRNRNISAFGLVPPLKAIEGGTTVAARALIAVTDFGVEEAELVEPLNALKKAGIEVTVAS
NSGESIQTVTGDKDWASKVNADSRLADAKASDYDLLVIPGGTVNADTLRIDEDGRRLVKEFATAGKPVGAICHGPWVLID
ADVAKGKTMTSYISIRPDLENAGASWVDKELFRCPGNGWVLLTSRNPNDLPAFAKALVDEIS

Specific function: Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=177, Percent_Identity=31.0734463276836, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI31543380, Length=177, Percent_Identity=31.0734463276836, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI87082219, Length=173, Percent_Identity=37.5722543352601, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI87081736, Length=178, Percent_Identity=30.3370786516854, Blast_Score=64, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28571932, Length=168, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 23370; Mature: 23370

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISHCGPCRGNSVVAGEAPLCRNRNISAFGLVPPLKAIEGGTTVAARALIAVTDFGVEEA
CCCCCCCCCCCEEEECCCCCCCCCCCCEEECCCCHHHHCCCCHHHHHEEEEEECCCCCHH
ELVEPLNALKKAGIEVTVASNSGESIQTVTGDKDWASKVNADSRLADAKASDYDLLVIPG
HHHHHHHHHHHCCEEEEEECCCCCEEEEEECCHHHHHHCCCCHHHHCCCCCCCEEEEECC
GTVNADTLRIDEDGRRLVKEFATAGKPVGAICHGPWVLIDADVAKGKTMTSYISIRPDLE
CCCCCCEEEECHHHHHHHHHHHHCCCCCCEEECCCEEEEECCCCCCCEEEEEEEECCCCC
NAGASWVDKELFRCPGNGWVLLTSRNPNDLPAFAKALVDEIS
CCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MISHCGPCRGNSVVAGEAPLCRNRNISAFGLVPPLKAIEGGTTVAARALIAVTDFGVEEA
CCCCCCCCCCCEEEECCCCCCCCCCCCEEECCCCHHHHCCCCHHHHHEEEEEECCCCCHH
ELVEPLNALKKAGIEVTVASNSGESIQTVTGDKDWASKVNADSRLADAKASDYDLLVIPG
HHHHHHHHHHHCCEEEEEECCCCCEEEEEECCHHHHHHCCCCHHHHCCCCCCCEEEEECC
GTVNADTLRIDEDGRRLVKEFATAGKPVGAICHGPWVLIDADVAKGKTMTSYISIRPDLE
CCCCCCEEEECHHHHHHHHHHHHCCCCCCEEECCCEEEEECCCCCCCEEEEEEEECCCCC
NAGASWVDKELFRCPGNGWVLLTSRNPNDLPAFAKALVDEIS
CCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 9298659 [H]