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The map label for this gene is nrdD [H]

Identifier: 50843575

GI number: 50843575

Start: 2315057

End: 2317399

Strand: Reverse

Name: nrdD [H]

Synonym: PPA2137

Alternate gene names: 50843575

Gene position: 2317399-2315057 (Counterclockwise)

Preceding gene: 50843578

Following gene: 50843574

Centisome position: 90.51

GC content: 61.33

Gene sequence:

>2343_bases
ATGTCGACGATCGTTCAACCAGACGACCAGACCATTAGTCAGCAACGCGCAGTACCGACGTCCATTCGCAAACGTGACGG
CAGGGTGATCCGCTTCGACTCGACGAAGATCGTCGAGGCTGTCCGTAAGGCTTTCGTGGCATGCGGGATTGGTACCTCGG
AGTTGCATGCATCTGAAGTTGCCCTGGAGGTCATGTCTCGGCTGAGCGAGATGGGCGAGGAGACCCCGGACGTTGAGACC
ATCCAGGATCTCGTCGAGAAGACACTCATGGACCAGGGACATGACGACGTCGCCAAGGCATACATCCTGTACCGACAGCG
CCGCACCGTCGCCCGTGACCAGCAGTCAGCATTGATGCGCACCCTGCGCGAGATCACCTTCGCGTCCGCAGAGGAAGCTG
ATGCCAAGCGGGAGAACGCCAACGTTGACGGCAACTCCGCTATGGGGTCGATGCTGCGCTATGGCACCGAGTCAGCCAAA
CAGTTCAACTTGCTGGAGGTACTCGACCCTGCCCACGCCGCCGCCCACCGTGACGGTGACATCCATATCCACGACCTCGA
TTTTCTTACTCTGACAACTACCTGCTGCCAGATTAACCTCACCGACTTGTTCGAGCACGGGTTCTCCACCGGCCACGGCG
TGCTGCGTGCCCCGCAGTCCATCGGGTCATACGCAGCCCTGGCTTGCATTGCCATCCAGTCCAACCAGAATGACCAGCAC
GGTGGTCAGGCCGTGCCAAATTTTGATCGTGACATGGCACCGGGCGTCGCCAAGACCTTTAAGCGCGCCGCCCAGACCGG
TCTGGCACGAATCTTCGAGGTTCTTGGGGGCGACGAGGACAAGGTCGACGAGGTGCGGGAAGCAGCCTCGGAATGGACGT
TGGAACCTGACGAGACTGGTCTTGCTGCCGAGCACGAGCAGGTCAGGCGGCTGTTCGCTGGACTCGTCGACGACACCGAT
CGCCTTGCCGAGCGGATTCGTCGTCAGGCCCTCGAAGAGACCCGACGCCAGACCTACCAGGCGATGGAGGCCCTCATCGC
TAACCTCAACACCATGAACTCGCGGGCCGGAGCGCAGACGCCATTCTCGTCGATCAACTACGGTACCGACACTCGCCCGG
AGGCGCGGATGGCCATGCGCTGCCTGTTGGAGGCCACCGAGGCAGGGCTGGGTGGCGGGGAGACCGCGATCTTCCCGATC
CAGATCTTCCGGGTACAGAAAGGGGTCAACCTCAACCCGGGCGATCCCAACTACGACCTGTTCCGGCTGGCGTGCCGGGT
GAGCGCCAAGCGGCTGTTCCCGAACTTCTCCTTCCAGGATGCCCCCTTCAACGCCGAGTTCTACCGGCCTGGCCACCCCG
AGACGGAAATCGCGTACATGGGTTGCCGCACTCGGGTGATGTCGAACGTGCATGACCCGTCCCGGGCCCAGACCTGGGGG
CGTGGAAACCTGTCGTTCACGTCAATCAACCTGCCCAGATTGGCCATCGAAGCCCATCACGACGTCGATGCTTTCTTCGC
TTCTTACGACCGGATGATTGATCTGGTCATTGACCAGCTCCTCGACCGTCTCAAGATCCAATCTCATAAGCTGGTGCGCA
ATTTTCCCTTCCTTATGGGCCAAGGGGTATGGATCGACTCCGAGGAGCTGCGTGCCGATGATTCCGTCGCCGAGGTGCTG
AAACACGGGACTCTCTCGGTGGGGTTCATCGGGCTTGCCGAGACGCTTACGGCGTTGATCGGAGTCCACCACGGTGAGTC
GGAAGAAGCGCAACAGCTTGGCCTGCGGATCGTTGGTCACCTGCAGGAACGTATGGACGAGGCTGCCGAGCGCACCGGCC
TGAACTTCTCGGCCCTGGCCACCCCGGCTGAGGGACTGTCGGGGCGGTTCGTCCGAATGGATCGGCAGCGCTACGGGTCG
ATCCCGGGAGTGACCGACCGCGAGTACTACACGAACAGCTTCCACGTGCCGGTCTGGTACCACATCGGTGCCGCAGACAA
GATCGCCATCGAGGCTCCCTACCACGCCTTCACCAATGGTGGCCATATTTCCTACGTGGAGCTGTCGGGGGATCCAGCCC
GCAATGTCGACGCCTTCGTGGCGATCGTGCGACACATGGCAGCCAGTGGCATCGGATACGGCTCTATCAACCATCCCGTC
GACCGGGATCCACAGTGCGGCTACACCGGAATTATCGATGACGAGTGTCCCGGATGCGGTCGGGCTGAAGAATCGGGCCC
CTTCGACCGGATCCGTCGCATCACTGGATATCTGGTGGGCACTTTGGATCGTTTCAACGACGCCAAGCGCGCCGAAGTCA
GAGACCGCGTTAAGCACGGGTGA

Upstream 100 bases:

>100_bases
ACCTGCCAGTACCCGGGTCAACGACCCGGTACGACAACGGGCGCGCGGGACGACCCGGGGCTATCCATGCTCCACCTGTG
CGCTGCTTCGAGGAGTGAGC

Downstream 100 bases:

>100_bases
GGATCGCTGGGATCGAGCCGGAGTCGATCGTTGACGGCCCCGGCATCCGTTTCACGGTCTTTACCCAAGGGTGTCCGCTG
CAGTGTCCTGGGTGCCATAA

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 780; Mature: 779

Protein sequence:

>780_residues
MSTIVQPDDQTISQQRAVPTSIRKRDGRVIRFDSTKIVEAVRKAFVACGIGTSELHASEVALEVMSRLSEMGEETPDVET
IQDLVEKTLMDQGHDDVAKAYILYRQRRTVARDQQSALMRTLREITFASAEEADAKRENANVDGNSAMGSMLRYGTESAK
QFNLLEVLDPAHAAAHRDGDIHIHDLDFLTLTTTCCQINLTDLFEHGFSTGHGVLRAPQSIGSYAALACIAIQSNQNDQH
GGQAVPNFDRDMAPGVAKTFKRAAQTGLARIFEVLGGDEDKVDEVREAASEWTLEPDETGLAAEHEQVRRLFAGLVDDTD
RLAERIRRQALEETRRQTYQAMEALIANLNTMNSRAGAQTPFSSINYGTDTRPEARMAMRCLLEATEAGLGGGETAIFPI
QIFRVQKGVNLNPGDPNYDLFRLACRVSAKRLFPNFSFQDAPFNAEFYRPGHPETEIAYMGCRTRVMSNVHDPSRAQTWG
RGNLSFTSINLPRLAIEAHHDVDAFFASYDRMIDLVIDQLLDRLKIQSHKLVRNFPFLMGQGVWIDSEELRADDSVAEVL
KHGTLSVGFIGLAETLTALIGVHHGESEEAQQLGLRIVGHLQERMDEAAERTGLNFSALATPAEGLSGRFVRMDRQRYGS
IPGVTDREYYTNSFHVPVWYHIGAADKIAIEAPYHAFTNGGHISYVELSGDPARNVDAFVAIVRHMAASGIGYGSINHPV
DRDPQCGYTGIIDDECPGCGRAEESGPFDRIRRITGYLVGTLDRFNDAKRAEVRDRVKHG

Sequences:

>Translated_780_residues
MSTIVQPDDQTISQQRAVPTSIRKRDGRVIRFDSTKIVEAVRKAFVACGIGTSELHASEVALEVMSRLSEMGEETPDVET
IQDLVEKTLMDQGHDDVAKAYILYRQRRTVARDQQSALMRTLREITFASAEEADAKRENANVDGNSAMGSMLRYGTESAK
QFNLLEVLDPAHAAAHRDGDIHIHDLDFLTLTTTCCQINLTDLFEHGFSTGHGVLRAPQSIGSYAALACIAIQSNQNDQH
GGQAVPNFDRDMAPGVAKTFKRAAQTGLARIFEVLGGDEDKVDEVREAASEWTLEPDETGLAAEHEQVRRLFAGLVDDTD
RLAERIRRQALEETRRQTYQAMEALIANLNTMNSRAGAQTPFSSINYGTDTRPEARMAMRCLLEATEAGLGGGETAIFPI
QIFRVQKGVNLNPGDPNYDLFRLACRVSAKRLFPNFSFQDAPFNAEFYRPGHPETEIAYMGCRTRVMSNVHDPSRAQTWG
RGNLSFTSINLPRLAIEAHHDVDAFFASYDRMIDLVIDQLLDRLKIQSHKLVRNFPFLMGQGVWIDSEELRADDSVAEVL
KHGTLSVGFIGLAETLTALIGVHHGESEEAQQLGLRIVGHLQERMDEAAERTGLNFSALATPAEGLSGRFVRMDRQRYGS
IPGVTDREYYTNSFHVPVWYHIGAADKIAIEAPYHAFTNGGHISYVELSGDPARNVDAFVAIVRHMAASGIGYGSINHPV
DRDPQCGYTGIIDDECPGCGRAEESGPFDRIRRITGYLVGTLDRFNDAKRAEVRDRVKHG
>Mature_779_residues
STIVQPDDQTISQQRAVPTSIRKRDGRVIRFDSTKIVEAVRKAFVACGIGTSELHASEVALEVMSRLSEMGEETPDVETI
QDLVEKTLMDQGHDDVAKAYILYRQRRTVARDQQSALMRTLREITFASAEEADAKRENANVDGNSAMGSMLRYGTESAKQ
FNLLEVLDPAHAAAHRDGDIHIHDLDFLTLTTTCCQINLTDLFEHGFSTGHGVLRAPQSIGSYAALACIAIQSNQNDQHG
GQAVPNFDRDMAPGVAKTFKRAAQTGLARIFEVLGGDEDKVDEVREAASEWTLEPDETGLAAEHEQVRRLFAGLVDDTDR
LAERIRRQALEETRRQTYQAMEALIANLNTMNSRAGAQTPFSSINYGTDTRPEARMAMRCLLEATEAGLGGGETAIFPIQ
IFRVQKGVNLNPGDPNYDLFRLACRVSAKRLFPNFSFQDAPFNAEFYRPGHPETEIAYMGCRTRVMSNVHDPSRAQTWGR
GNLSFTSINLPRLAIEAHHDVDAFFASYDRMIDLVIDQLLDRLKIQSHKLVRNFPFLMGQGVWIDSEELRADDSVAEVLK
HGTLSVGFIGLAETLTALIGVHHGESEEAQQLGLRIVGHLQERMDEAAERTGLNFSALATPAEGLSGRFVRMDRQRYGSI
PGVTDREYYTNSFHVPVWYHIGAADKIAIEAPYHAFTNGGHISYVELSGDPARNVDAFVAIVRHMAASGIGYGSINHPVD
RDPQCGYTGIIDDECPGCGRAEESGPFDRIRRITGYLVGTLDRFNDAKRAEVRDRVKHG

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=773, Percent_Identity=30.9184993531695, Blast_Score=321, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 86427; Mature: 86296

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIVQPDDQTISQQRAVPTSIRKRDGRVIRFDSTKIVEAVRKAFVACGIGTSELHASEV
CCCCCCCCCHHHHHHHCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHH
ALEVMSRLSEMGEETPDVETIQDLVEKTLMDQGHDDVAKAYILYRQRRTVARDQQSALMR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLREITFASAEEADAKRENANVDGNSAMGSMLRYGTESAKQFNLLEVLDPAHAAAHRDGD
HHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHCHHHHHHCCCCC
IHIHDLDFLTLTTTCCQINLTDLFEHGFSTGHGVLRAPQSIGSYAALACIAIQSNQNDQH
EEEEECHHHHHHHHHHCCCHHHHHHCCCCCCCCHHCCCHHHCCHHHHHEEEEECCCCCCC
GGQAVPNFDRDMAPGVAKTFKRAAQTGLARIFEVLGGDEDKVDEVREAASEWTLEPDETG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
LAAEHEQVRRLFAGLVDDTDRLAERIRRQALEETRRQTYQAMEALIANLNTMNSRAGAQT
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PFSSINYGTDTRPEARMAMRCLLEATEAGLGGGETAIFPIQIFRVQKGVNLNPGDPNYDL
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHH
FRLACRVSAKRLFPNFSFQDAPFNAEFYRPGHPETEIAYMGCRTRVMSNVHDPSRAQTWG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCHHHCCCC
RGNLSFTSINLPRLAIEAHHDVDAFFASYDRMIDLVIDQLLDRLKIQSHKLVRNFPFLMG
CCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHC
QGVWIDSEELRADDSVAEVLKHGTLSVGFIGLAETLTALIGVHHGESEEAQQLGLRIVGH
CCCEECHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LQERMDEAAERTGLNFSALATPAEGLSGRFVRMDRQRYGSIPGVTDREYYTNSFHVPVWY
HHHHHHHHHHHCCCCCHHHCCCCCCCCCCCEEECHHHCCCCCCCCCCCCCCCEECCEEEE
HIGAADKIAIEAPYHAFTNGGHISYVELSGDPARNVDAFVAIVRHMAASGIGYGSINHPV
EECCCCEEEEECCCHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DRDPQCGYTGIIDDECPGCGRAEESGPFDRIRRITGYLVGTLDRFNDAKRAEVRDRVKHG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
STIVQPDDQTISQQRAVPTSIRKRDGRVIRFDSTKIVEAVRKAFVACGIGTSELHASEV
CCCCCCCCHHHHHHHCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHH
ALEVMSRLSEMGEETPDVETIQDLVEKTLMDQGHDDVAKAYILYRQRRTVARDQQSALMR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLREITFASAEEADAKRENANVDGNSAMGSMLRYGTESAKQFNLLEVLDPAHAAAHRDGD
HHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHCHHHHHHCCCCC
IHIHDLDFLTLTTTCCQINLTDLFEHGFSTGHGVLRAPQSIGSYAALACIAIQSNQNDQH
EEEEECHHHHHHHHHHCCCHHHHHHCCCCCCCCHHCCCHHHCCHHHHHEEEEECCCCCCC
GGQAVPNFDRDMAPGVAKTFKRAAQTGLARIFEVLGGDEDKVDEVREAASEWTLEPDETG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
LAAEHEQVRRLFAGLVDDTDRLAERIRRQALEETRRQTYQAMEALIANLNTMNSRAGAQT
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PFSSINYGTDTRPEARMAMRCLLEATEAGLGGGETAIFPIQIFRVQKGVNLNPGDPNYDL
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHH
FRLACRVSAKRLFPNFSFQDAPFNAEFYRPGHPETEIAYMGCRTRVMSNVHDPSRAQTWG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCHHHCCCC
RGNLSFTSINLPRLAIEAHHDVDAFFASYDRMIDLVIDQLLDRLKIQSHKLVRNFPFLMG
CCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHC
QGVWIDSEELRADDSVAEVLKHGTLSVGFIGLAETLTALIGVHHGESEEAQQLGLRIVGH
CCCEECHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LQERMDEAAERTGLNFSALATPAEGLSGRFVRMDRQRYGSIPGVTDREYYTNSFHVPVWY
HHHHHHHHHHHCCCCCHHHCCCCCCCCCCCEEECHHHCCCCCCCCCCCCCCCEECCEEEE
HIGAADKIAIEAPYHAFTNGGHISYVELSGDPARNVDAFVAIVRHMAASGIGYGSINHPV
EECCCCEEEEECCCHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DRDPQCGYTGIIDDECPGCGRAEESGPFDRIRRITGYLVGTLDRFNDAKRAEVRDRVKHG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]