Click here to switch to the map view.

The map label for this gene is cat1 [H]

Identifier: 50843497

GI number: 50843497

Start: 2229068

End: 2230582

Strand: Direct

Name: cat1 [H]

Synonym: PPA2053

Alternate gene names: 50843497

Gene position: 2229068-2230582 (Clockwise)

Preceding gene: 50843496

Following gene: 50843501

Centisome position: 87.06

GC content: 60.92

Gene sequence:

>1515_bases
ATGTCAGAGCGGATTGCCAACGCAGCCCTGCGTCAGAAAGTGATGAGCGCGGACGACGCGGCTGCCCTCATCCATGACGG
CGACCAGATCGGATTCGGTGGATTCACTGGGTCGGGCTACCCCAAGGAACTTCCAGGCGCACTGGCCAAGCGCATCCAAG
AGTCCCACGGCCGTGGTGAGAAGTTCACCGTCAACGTCTTCACCGGAGCCTCGACCGCTCCTGAACTCGACGGCGCCCTC
GCCTCTGTCGACGGCATCGGCTGGCGTATGCCGTACCAGTCCGATCCCCAGATGCGAAGCAAGATCAACGACGGCACCTC
CTTCTATACCGACATCCATCTGTCGGAGTCGGGCATGATGGTGCGTCAGGGCTTCTTTGGCAAGGTCGACTTCGCCGTCA
TCGAGGCCACACGAATCACCGCGGACGGGGATGTCGTCCTCACCTCGTCGGTTGGCAACAACGCGGTCTACTGTGACACC
GCCGAGAAAGTCATCATCGAGGTAAATTCGTGGCAGTCCGAGGACCTCGAAGGAATGCACGACATCTACGGTGGTTTTGC
GCTTCCTCCGAACCGGGTGCCGATCCCGATTACCCATCCCGGTGACCGGATCGGTGACAAGTTCCTCCACATCCCCCAGA
ACAAGATTGTGGCGATCATCGAGACCGCAGGCCCCGACCGCAACACCCCGTTCAAGCCGATCGACGACGACTCTCGCAAG
ATCGCCGGATTCCTGCTCGACTTTTATGACAACGAGGTCAAGCAGGGACGCATCCCCAAGAACCTGCTGCCGCTCCAGTC
CGGCGTCGGCAACATCCCGAACGCCGTTCTTGACGGCCTGCTTCACTCCGACCTGGAGCATCTGACCTCGTACACCGAGG
TGATCCAGGACGGCATGATCGACCTCATCGACGCCGGCAAGCTTGACGTCGCCTCCGCTACCGCCTTCTCGCTGTCGCCT
GACTATGCGCACAAGATGAACGAGAATGCAGCCTTCTACCGCGATCACATCATTTTGCGCCCGCAGGAAATTTCGAACCA
CCCCGAGGTCATTCGCCGCCTCGGCGTCATCGGCGCTAACGGCATGATCGAGGCCGACATCTATGGCAATGTCAACTCGA
CCCATGTCATGGGCTCGCGGATGATGAACGGCATCGGTGGATCCGGCGACTTCACCCGCAATGCCTACATTTCGGCCTTC
GTGTCCCCATCGACAGCCAAGGGTGGCGCCATCTCGGCGATCGTCCCGATGGTCTCCCACGTCGACCACACCGAGCACGA
CGGCATGGTTATCATCACCGAGCAAGGCATCGCTGATCTGCGTGGCCTGGCCCCACGCCAGCGCGCCCGGAAGATCATCG
AGAACTGTGCCCACCCGGACTACCGTCCGATGCTGCTCGACTACTACGAGCGTGCGCTGCGCGACTGCAAGTTCAAGCAC
ACCCCGCACCTGCTGGGTGAGGCGTACTCATGGCACACCCGGTTCCTCGAGACCGGCACCATGAAGAAGGACTGA

Upstream 100 bases:

>100_bases
GGACCGCCTTCACCGGGAACGAAACAGTGTTTCTTCGACGGTTCACAGGTAGTGCTGTGTGCCGTCACCGACAACCAGCC
GCACGGCGGCAGGAGGACAG

Downstream 100 bases:

>100_bases
GGTCTTACTTACAACCCTGACCCACAATCGCCCCAGGACCGTTTCGGTTCCGGGGCGATCATTATGTGCGGCAGTCGCGA
CAAGTGACGATTTTCGTCAC

Product: coenzyme A transferase (putative succinyl-CoA or butyryl-CoA:coenzyme A transferase)

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MSERIANAALRQKVMSADDAAALIHDGDQIGFGGFTGSGYPKELPGALAKRIQESHGRGEKFTVNVFTGASTAPELDGAL
ASVDGIGWRMPYQSDPQMRSKINDGTSFYTDIHLSESGMMVRQGFFGKVDFAVIEATRITADGDVVLTSSVGNNAVYCDT
AEKVIIEVNSWQSEDLEGMHDIYGGFALPPNRVPIPITHPGDRIGDKFLHIPQNKIVAIIETAGPDRNTPFKPIDDDSRK
IAGFLLDFYDNEVKQGRIPKNLLPLQSGVGNIPNAVLDGLLHSDLEHLTSYTEVIQDGMIDLIDAGKLDVASATAFSLSP
DYAHKMNENAAFYRDHIILRPQEISNHPEVIRRLGVIGANGMIEADIYGNVNSTHVMGSRMMNGIGGSGDFTRNAYISAF
VSPSTAKGGAISAIVPMVSHVDHTEHDGMVIITEQGIADLRGLAPRQRARKIIENCAHPDYRPMLLDYYERALRDCKFKH
TPHLLGEAYSWHTRFLETGTMKKD

Sequences:

>Translated_504_residues
MSERIANAALRQKVMSADDAAALIHDGDQIGFGGFTGSGYPKELPGALAKRIQESHGRGEKFTVNVFTGASTAPELDGAL
ASVDGIGWRMPYQSDPQMRSKINDGTSFYTDIHLSESGMMVRQGFFGKVDFAVIEATRITADGDVVLTSSVGNNAVYCDT
AEKVIIEVNSWQSEDLEGMHDIYGGFALPPNRVPIPITHPGDRIGDKFLHIPQNKIVAIIETAGPDRNTPFKPIDDDSRK
IAGFLLDFYDNEVKQGRIPKNLLPLQSGVGNIPNAVLDGLLHSDLEHLTSYTEVIQDGMIDLIDAGKLDVASATAFSLSP
DYAHKMNENAAFYRDHIILRPQEISNHPEVIRRLGVIGANGMIEADIYGNVNSTHVMGSRMMNGIGGSGDFTRNAYISAF
VSPSTAKGGAISAIVPMVSHVDHTEHDGMVIITEQGIADLRGLAPRQRARKIIENCAHPDYRPMLLDYYERALRDCKFKH
TPHLLGEAYSWHTRFLETGTMKKD
>Mature_503_residues
SERIANAALRQKVMSADDAAALIHDGDQIGFGGFTGSGYPKELPGALAKRIQESHGRGEKFTVNVFTGASTAPELDGALA
SVDGIGWRMPYQSDPQMRSKINDGTSFYTDIHLSESGMMVRQGFFGKVDFAVIEATRITADGDVVLTSSVGNNAVYCDTA
EKVIIEVNSWQSEDLEGMHDIYGGFALPPNRVPIPITHPGDRIGDKFLHIPQNKIVAIIETAGPDRNTPFKPIDDDSRKI
AGFLLDFYDNEVKQGRIPKNLLPLQSGVGNIPNAVLDGLLHSDLEHLTSYTEVIQDGMIDLIDAGKLDVASATAFSLSPD
YAHKMNENAAFYRDHIILRPQEISNHPEVIRRLGVIGANGMIEADIYGNVNSTHVMGSRMMNGIGGSGDFTRNAYISAFV
SPSTAKGGAISAIVPMVSHVDHTEHDGMVIITEQGIADLRGLAPRQRARKIIENCAHPDYRPMLLDYYERALRDCKFKHT
PHLLGEAYSWHTRFLETGTMKKD

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=488, Percent_Identity=46.5163934426229, Blast_Score=437, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17538151, Length=496, Percent_Identity=26.6129032258064, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32563853, Length=236, Percent_Identity=31.3559322033898, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319456, Length=518, Percent_Identity=43.4362934362934, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55120; Mature: 54989

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERIANAALRQKVMSADDAAALIHDGDQIGFGGFTGSGYPKELPGALAKRIQESHGRGE
CCHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
KFTVNVFTGASTAPELDGALASVDGIGWRMPYQSDPQMRSKINDGTSFYTDIHLSESGMM
EEEEEEEECCCCCCCCCCHHHHCCCCCEECCCCCCHHHHHHCCCCCEEEEEEEECCCCCE
VRQGFFGKVDFAVIEATRITADGDVVLTSSVGNNAVYCDTAEKVIIEVNSWQSEDLEGMH
EECCCCCCEEEEEEEEEEEECCCCEEEEECCCCCEEEEECCCEEEEEECCCCCCCHHHHH
DIYGGFALPPNRVPIPITHPGDRIGDKFLHIPQNKIVAIIETAGPDRNTPFKPIDDDSRK
HHHCCCCCCCCCCEEEECCCCHHHCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCCHHH
IAGFLLDFYDNEVKQGRIPKNLLPLQSGVGNIPNAVLDGLLHSDLEHLTSYTEVIQDGMI
HHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCE
DLIDAGKLDVASATAFSLSPDYAHKMNENAAFYRDHIILRPQEISNHPEVIRRLGVIGAN
EECCCCCEEECCCEEEECCCHHHHHCCCCCEEEECEEEECCHHHCCCHHHHHHHHCCCCC
GMIEADIYGNVNSTHVMGSRMMNGIGGSGDFTRNAYISAFVSPSTAKGGAISAIVPMVSH
CEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHH
VDHTEHDGMVIITEQGIADLRGLAPRQRARKIIENCAHPDYRPMLLDYYERALRDCKFKH
CCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
TPHLLGEAYSWHTRFLETGTMKKD
CCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SERIANAALRQKVMSADDAAALIHDGDQIGFGGFTGSGYPKELPGALAKRIQESHGRGE
CHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
KFTVNVFTGASTAPELDGALASVDGIGWRMPYQSDPQMRSKINDGTSFYTDIHLSESGMM
EEEEEEEECCCCCCCCCCHHHHCCCCCEECCCCCCHHHHHHCCCCCEEEEEEEECCCCCE
VRQGFFGKVDFAVIEATRITADGDVVLTSSVGNNAVYCDTAEKVIIEVNSWQSEDLEGMH
EECCCCCCEEEEEEEEEEEECCCCEEEEECCCCCEEEEECCCEEEEEECCCCCCCHHHHH
DIYGGFALPPNRVPIPITHPGDRIGDKFLHIPQNKIVAIIETAGPDRNTPFKPIDDDSRK
HHHCCCCCCCCCCEEEECCCCHHHCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCCHHH
IAGFLLDFYDNEVKQGRIPKNLLPLQSGVGNIPNAVLDGLLHSDLEHLTSYTEVIQDGMI
HHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCE
DLIDAGKLDVASATAFSLSPDYAHKMNENAAFYRDHIILRPQEISNHPEVIRRLGVIGAN
EECCCCCEEECCCEEEECCCHHHHHCCCCCEEEECEEEECCHHHCCCHHHHHHHHCCCCC
GMIEADIYGNVNSTHVMGSRMMNGIGGSGDFTRNAYISAFVSPSTAKGGAISAIVPMVSH
CEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHH
VDHTEHDGMVIITEQGIADLRGLAPRQRARKIIENCAHPDYRPMLLDYYERALRDCKFKH
CCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
TPHLLGEAYSWHTRFLETGTMKKD
CCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]