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The map label for this gene is dnaJ2

Identifier: 50843482

GI number: 50843482

Start: 2211718

End: 2212860

Strand: Reverse

Name: dnaJ2

Synonym: PPA2038

Alternate gene names: 50843482

Gene position: 2212860-2211718 (Counterclockwise)

Preceding gene: 50843483

Following gene: 50843481

Centisome position: 86.43

GC content: 62.12

Gene sequence:

>1143_bases
ATGAGTACCAAGGACTGGGCTGAGAAGGATTACTACAAGATCCTCGGTGTCTCCAAGGACGCGAAGCCCGAAGAAATTAA
GAAGGCGTTCCGCAAGATCGCCCGGGACAACCATCCCGACTCCCACCCTGGTGATAAAGCCGCTGAGGCTCGTTTCAAGG
AGGCCTCGGAGGCCAACGACGTGCTGTCGAACGCCAAGAAGCGCAAGGAGTACGACCAGGCTCGTAGCCTGTTCGGATCA
GCAGGTGGATTCCGGTTCCCGCGTGGTGGAGCGCAGACCAGCGTCAACGTGGAGGATTTTCTACGTACTGCCTCCAACGG
GGACGGGTTCGGTGACCTGTTCGGCAATCTCTTTGGGGCTAGCGGGGGACGTCGCACAGCGTCCCGGTCGCCACGTCGGG
GAGCTGACGTTGAGGGGGAGACGACGATTTCCTTCGACGATGCCGTGTCTGGGACCACCGTCACTATGGACATGGTCTCT
CAGGCACCCTGCCAGGCATGTCGGGGGACTGGAGCTCGGGCTGGTACCGTTCCGCGAGTGTGCTCGACCTGTCAAGGGTC
GGGTATGCATGCTAGCTCGGCTGGTGGGGTGTTCGAGATGACCGAGCCCTGCCCGGATTGTCACGGTCGAGGCATGATCG
TTGAGGACCCCTGTCAGGTCTGCCACGGATCGGGTCGGGCTAAATCCACCAAGTCTATGCAGACCCGCATCCCTGCCGGG
GTGGAGGATGGTCAGCGCATTCGCATTAAGGGCAAGGGGTCTCCTGGCGAGAATGGCGGGAAAGCGGGTGACCTTTACGT
CAAGGTGACGGTGCGTCCACACGAGATCTTTGGTCGTGACGGCCACAACCTCACCGTCACCGTGCCAGTGACCTTTCCAG
AGGCCACTCTGGGCGCCGAGGTGGAGGTGCCGACTCTAGCGGGAACGACCGTTCGACTGCGTATTCCGGCTGGGACACCG
AATGGCCGTACCTTCCGGGTGCGGGGGCGTGGAGTGCCGCGTTCCGACGGCAGCAGGGGGGATCTACTCGCCACCGTTGA
GATTGCTGTCCCGGAGAGTCTTGACGACGACGCCCGGCATGTCGTGGAGAGACTTCGTGACTCCCTCCCCCAGGCCACTC
CGCGACCATGGGAGGTGAAGTGA

Upstream 100 bases:

>100_bases
GATGACGAGACGCCGCGTAACGAGTGACGGCGATCTTGGCCGACTACGATGAGGCCACCATGACCGCAAATCCGACGATG
GCCAGGGAGGGAGGAATTAG

Downstream 100 bases:

>100_bases
GATGGTGAGGCGCAGCAGGAATCTATCCGACGCTGTTGATCTTGCGGTGATCGACAAGGACGCTGCCATCTTCGCCATCT
CAGTGGCGGCAGAGCTCGCC

Product: chaperone protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSTKDWAEKDYYKILGVSKDAKPEEIKKAFRKIARDNHPDSHPGDKAAEARFKEASEANDVLSNAKKRKEYDQARSLFGS
AGGFRFPRGGAQTSVNVEDFLRTASNGDGFGDLFGNLFGASGGRRTASRSPRRGADVEGETTISFDDAVSGTTVTMDMVS
QAPCQACRGTGARAGTVPRVCSTCQGSGMHASSAGGVFEMTEPCPDCHGRGMIVEDPCQVCHGSGRAKSTKSMQTRIPAG
VEDGQRIRIKGKGSPGENGGKAGDLYVKVTVRPHEIFGRDGHNLTVTVPVTFPEATLGAEVEVPTLAGTTVRLRIPAGTP
NGRTFRVRGRGVPRSDGSRGDLLATVEIAVPESLDDDARHVVERLRDSLPQATPRPWEVK

Sequences:

>Translated_380_residues
MSTKDWAEKDYYKILGVSKDAKPEEIKKAFRKIARDNHPDSHPGDKAAEARFKEASEANDVLSNAKKRKEYDQARSLFGS
AGGFRFPRGGAQTSVNVEDFLRTASNGDGFGDLFGNLFGASGGRRTASRSPRRGADVEGETTISFDDAVSGTTVTMDMVS
QAPCQACRGTGARAGTVPRVCSTCQGSGMHASSAGGVFEMTEPCPDCHGRGMIVEDPCQVCHGSGRAKSTKSMQTRIPAG
VEDGQRIRIKGKGSPGENGGKAGDLYVKVTVRPHEIFGRDGHNLTVTVPVTFPEATLGAEVEVPTLAGTTVRLRIPAGTP
NGRTFRVRGRGVPRSDGSRGDLLATVEIAVPESLDDDARHVVERLRDSLPQATPRPWEVK
>Mature_379_residues
STKDWAEKDYYKILGVSKDAKPEEIKKAFRKIARDNHPDSHPGDKAAEARFKEASEANDVLSNAKKRKEYDQARSLFGSA
GGFRFPRGGAQTSVNVEDFLRTASNGDGFGDLFGNLFGASGGRRTASRSPRRGADVEGETTISFDDAVSGTTVTMDMVSQ
APCQACRGTGARAGTVPRVCSTCQGSGMHASSAGGVFEMTEPCPDCHGRGMIVEDPCQVCHGSGRAKSTKSMQTRIPAGV
EDGQRIRIKGKGSPGENGGKAGDLYVKVTVRPHEIFGRDGHNLTVTVPVTFPEATLGAEVEVPTLAGTTVRLRIPAGTPN
GRTFRVRGRGVPRSDGSRGDLLATVEIAVPESLDDDARHVVERLRDSLPQATPRPWEVK

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI205360838, Length=359, Percent_Identity=32.033426183844, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI205360840, Length=358, Percent_Identity=32.122905027933, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI194328760, Length=356, Percent_Identity=30.0561797752809, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI194328758, Length=356, Percent_Identity=30.0561797752809, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI4504511, Length=370, Percent_Identity=29.7297297297297, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI5031741, Length=383, Percent_Identity=29.7650130548303, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI7706495, Length=368, Percent_Identity=29.0760869565217, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI194328762, Length=320, Percent_Identity=27.5, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI6631085, Length=371, Percent_Identity=29.6495956873315, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI5453690, Length=366, Percent_Identity=27.3224043715847, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4885495, Length=65, Percent_Identity=55.3846153846154, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI17388799, Length=65, Percent_Identity=55.3846153846154, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI23503241, Length=99, Percent_Identity=45.4545454545455, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI201862587, Length=65, Percent_Identity=56.9230769230769, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI201862518, Length=65, Percent_Identity=56.9230769230769, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI56549115, Length=65, Percent_Identity=56.9230769230769, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI21553335, Length=65, Percent_Identity=52.3076923076923, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI47777312, Length=111, Percent_Identity=41.4414414414414, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI9558755, Length=202, Percent_Identity=32.1782178217822, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI29126218, Length=94, Percent_Identity=39.3617021276596, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI194306642, Length=65, Percent_Identity=53.8461538461538, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI194306640, Length=65, Percent_Identity=53.8461538461538, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI72534740, Length=98, Percent_Identity=40.8163265306122, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786197, Length=365, Percent_Identity=42.7397260273973, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1787235, Length=368, Percent_Identity=32.0652173913043, Blast_Score=147, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17553096, Length=375, Percent_Identity=30.9333333333333, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17553098, Length=375, Percent_Identity=30.9333333333333, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17507263, Length=374, Percent_Identity=29.144385026738, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI212645553, Length=373, Percent_Identity=27.0777479892761, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17563890, Length=255, Percent_Identity=26.2745098039216, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17534355, Length=74, Percent_Identity=55.4054054054054, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17554644, Length=116, Percent_Identity=37.0689655172414, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6324265, Length=371, Percent_Identity=31.266846361186, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321094, Length=380, Percent_Identity=31.5789473684211, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323870, Length=358, Percent_Identity=28.7709497206704, Blast_Score=126, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6323119, Length=401, Percent_Identity=24.6882793017456, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320888, Length=110, Percent_Identity=39.0909090909091, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI45552813, Length=386, Percent_Identity=30.0518134715026, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI45552811, Length=387, Percent_Identity=27.390180878553, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI45549272, Length=386, Percent_Identity=30.0518134715026, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24646562, Length=375, Percent_Identity=28.2666666666667, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646560, Length=375, Percent_Identity=28.2666666666667, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646558, Length=375, Percent_Identity=28.2666666666667, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646556, Length=375, Percent_Identity=28.2666666666667, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21357547, Length=375, Percent_Identity=28.2666666666667, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19920464, Length=374, Percent_Identity=27.0053475935829, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI20129487, Length=378, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24584014, Length=378, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI85726398, Length=384, Percent_Identity=28.125, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574949, Length=367, Percent_Identity=24.7956403269755, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI18858081, Length=369, Percent_Identity=28.1842818428184, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI161077138, Length=69, Percent_Identity=52.1739130434783, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24654066, Length=65, Percent_Identity=53.8461538461538, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24654070, Length=65, Percent_Identity=53.8461538461538, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24654068, Length=65, Percent_Identity=53.8461538461538, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24654072, Length=65, Percent_Identity=53.8461538461538, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24658562, Length=64, Percent_Identity=53.125, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658555, Length=64, Percent_Identity=53.125, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584630, Length=69, Percent_Identity=49.2753623188406, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17648033, Length=69, Percent_Identity=49.2753623188406, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAJ2_PROAC (Q6A662)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056709.1
- ProteinModelPortal:   Q6A662
- GeneID:   2933032
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA2038
- NMPDR:   fig|267747.1.peg.1986
- HOGENOM:   HBG635315
- OMA:   YDQFGFY
- ProtClustDB:   CLSK2764329
- BioCyc:   PACN267747:PPA2038-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01152
- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:2.10.230.10
- PANTHER:   PTHR11821
- PRINTS:   PR00625
- SMART:   SM00271
- TIGRFAMs:   TIGR02349

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG; SSF46565 DnaJ_N; SSF49493 HSP40_DnaJ_pep; SSF57938 HSP_DnaJ_cys-rich

EC number: NA

Molecular weight: Translated: 40573; Mature: 40442

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2; PS51188 ZF_CR; PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKDWAEKDYYKILGVSKDAKPEEIKKAFRKIARDNHPDSHPGDKAAEARFKEASEAND
CCCCHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VLSNAKKRKEYDQARSLFGSAGGFRFPRGGAQTSVNVEDFLRTASNGDGFGDLFGNLFGA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCC
SGGRRTASRSPRRGADVEGETTISFDDAVSGTTVTMDMVSQAPCQACRGTGARAGTVPRV
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCHHH
CSTCQGSGMHASSAGGVFEMTEPCPDCHGRGMIVEDPCQVCHGSGRAKSTKSMQTRIPAG
HHHCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECHHHHHCCCCCCCCHHHHHHHCCCC
VEDGQRIRIKGKGSPGENGGKAGDLYVKVTVRPHEIFGRDGHNLTVTVPVTFPEATLGAE
CCCCCEEEEEECCCCCCCCCCCCEEEEEEEECHHHHHCCCCCEEEEEEEEECCCHHCCCE
VEVPTLAGTTVRLRIPAGTPNGRTFRVRGRGVPRSDGSRGDLLATVEIAVPESLDDDARH
EEECEECCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHHH
VVERLRDSLPQATPRPWEVK
HHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
STKDWAEKDYYKILGVSKDAKPEEIKKAFRKIARDNHPDSHPGDKAAEARFKEASEAND
CCCHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VLSNAKKRKEYDQARSLFGSAGGFRFPRGGAQTSVNVEDFLRTASNGDGFGDLFGNLFGA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCC
SGGRRTASRSPRRGADVEGETTISFDDAVSGTTVTMDMVSQAPCQACRGTGARAGTVPRV
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCHHH
CSTCQGSGMHASSAGGVFEMTEPCPDCHGRGMIVEDPCQVCHGSGRAKSTKSMQTRIPAG
HHHCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECHHHHHCCCCCCCCHHHHHHHCCCC
VEDGQRIRIKGKGSPGENGGKAGDLYVKVTVRPHEIFGRDGHNLTVTVPVTFPEATLGAE
CCCCCEEEEEECCCCCCCCCCCCEEEEEEEECHHHHHCCCCCEEEEEEEEECCCHHCCCE
VEVPTLAGTTVRLRIPAGTPNGRTFRVRGRGVPRSDGSRGDLLATVEIAVPESLDDDARH
EEECEECCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHHH
VVERLRDSLPQATPRPWEVK
HHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA