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The map label for this gene is dedA [H]

Identifier: 50843460

GI number: 50843460

Start: 2186460

End: 2187254

Strand: Direct

Name: dedA [H]

Synonym: PPA2014

Alternate gene names: 50843460

Gene position: 2186460-2187254 (Clockwise)

Preceding gene: 50843456

Following gene: 50843464

Centisome position: 85.4

GC content: 57.61

Gene sequence:

>795_bases
GTGAAGGGGCATCAGCGAGTTCATCAGCGGACGAGGCACACACGGACCAAAGATAGTCTTGACCCTATGTCGAGTCTCCT
CATGACCCTCCCAGCCCTGCTCACCCCAACCTGGATGGACCCTCAGGCCATCATCCAGGGCACCGGTGCTGCTGCTCTGT
GGATCGTCGCGCTGATCGCCTTCGCCGAATGCGGCCTTGCCGTGTTCTTCATGCCCGGAGACTCTTTGCTTTTTGCTCTG
GGAATGTTTGCCGCCGTGGGCGTTAACTCAACCGTCCCTTTGGTCCATTACGGATCTGTGACGACGACCCTCATCATCGT
CAACGTGGTCCTCATCATCTGCGCTATCGCAGGAAATATCTGCGGTTACTGGATCGGCTACCTGGTTGGCCCGAAGCTTT
TCCGAGAGCGAGAAGGATTCATGGGTAAGGTGTTCTCCCCTAAACATGTGGACACCACCCATGAGTTCTTCCGCAAGCAT
GGTTCCGTAGCGCTCATCCTGGCCCGTTTCGTACCGATCGTGCGCACCTTCGTCACCATGATTGCCGGCGTGGGACGGAT
GACGTTTCAGAAATTCATCACCTATACCGCTATCGGCGGCATACTCTGGGTGCTCATCGCTGTCCAGGCTGGTTATTTCC
TCGGCCAAATCCCCGTCGTTCGGAACAATTTCGAGGCGGCTCTGCTCCTCATCATCGTGGTGTCAGTGCTGCCGATGGGT
GTCGAATGGCTCAAGGCCCGACGCAAGGGTCAGGTCAGCCAGCCACAATCAGCTCGGCGGTCCCGCGTCGAGTGA

Upstream 100 bases:

>100_bases
GAGGCCAACAGCTCAGGATCGAGTCTCGGGTCATCAGGCCACGGTTTGGGCATCGGCCCAACACCTACGACTGTAGTCCC
TAACTGGCTGGGAGTCTGCA

Downstream 100 bases:

>100_bases
AGGCCGAGCTGAACGTGCCGTAGGTGAGGAAATCGACTCACCTACGACGGGAGTTCGCTTGCCACGGCTGGACCTGCCCC
GGCGCTAGCCATCCTTCCTC

Product: DedA family membrane protein

Products: NA

Alternate protein names: Protein DSG-1 [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKGHQRVHQRTRHTRTKDSLDPMSSLLMTLPALLTPTWMDPQAIIQGTGAAALWIVALIAFAECGLAVFFMPGDSLLFAL
GMFAAVGVNSTVPLVHYGSVTTTLIIVNVVLIICAIAGNICGYWIGYLVGPKLFREREGFMGKVFSPKHVDTTHEFFRKH
GSVALILARFVPIVRTFVTMIAGVGRMTFQKFITYTAIGGILWVLIAVQAGYFLGQIPVVRNNFEAALLLIIVVSVLPMG
VEWLKARRKGQVSQPQSARRSRVE

Sequences:

>Translated_264_residues
MKGHQRVHQRTRHTRTKDSLDPMSSLLMTLPALLTPTWMDPQAIIQGTGAAALWIVALIAFAECGLAVFFMPGDSLLFAL
GMFAAVGVNSTVPLVHYGSVTTTLIIVNVVLIICAIAGNICGYWIGYLVGPKLFREREGFMGKVFSPKHVDTTHEFFRKH
GSVALILARFVPIVRTFVTMIAGVGRMTFQKFITYTAIGGILWVLIAVQAGYFLGQIPVVRNNFEAALLLIIVVSVLPMG
VEWLKARRKGQVSQPQSARRSRVE
>Mature_264_residues
MKGHQRVHQRTRHTRTKDSLDPMSSLLMTLPALLTPTWMDPQAIIQGTGAAALWIVALIAFAECGLAVFFMPGDSLLFAL
GMFAAVGVNSTVPLVHYGSVTTTLIIVNVVLIICAIAGNICGYWIGYLVGPKLFREREGFMGKVFSPKHVDTTHEFFRKH
GSVALILARFVPIVRTFVTMIAGVGRMTFQKFITYTAIGGILWVLIAVQAGYFLGQIPVVRNNFEAALLLIIVVSVLPMG
VEWLKARRKGQVSQPQSARRSRVE

Specific function: Unknown

COG id: COG0586

COG function: function code S; Uncharacterized membrane-associated protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dedA family [H]

Homologues:

Organism=Escherichia coli, GI1788656, Length=192, Percent_Identity=43.75, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789481, Length=166, Percent_Identity=31.9277108433735, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789384, Length=179, Percent_Identity=26.8156424581006, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015414 [H]

Pfam domain/function: PF09335 SNARE_assoc [H]

EC number: NA

Molecular weight: Translated: 29040; Mature: 29040

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCCCHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]