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The map label for this gene is purQ

Identifier: 50843434

GI number: 50843434

Start: 2158399

End: 2159073

Strand: Reverse

Name: purQ

Synonym: PPA1987

Alternate gene names: 50843434

Gene position: 2159073-2158399 (Counterclockwise)

Preceding gene: 50843435

Following gene: 50843429

Centisome position: 84.33

GC content: 60.89

Gene sequence:

>675_bases
ATGGTGCGCATTGGAGTCGTCACCTTCCCTGGCACTCTCGACGACCAGGATGCAGCGCGGGCCGTTCGCCTGGCCGGGGC
TGAGCCTGTGTCGTTGTGGTACGCCTCGACCGATCTGGCTGGGGTCGACGCCGTCATCCTTCCGGGAGGCTTCTCTTATG
GTGATTACCTGCGTGCAGGAGCTTTGGCTGCTGCCTCGCCAGTGATGTCGTCTATTCGCAGAGCTGCCGATGGGGGCCTG
CCAGTGCTCGGTATCTGCAACGGGTTTCAGGTACTGTGCGAATCCCATCTGCTGCCTGGCACCCTGATGCGTAACGAGAA
ACGACGCTTCCACTGTTCGGTGCAGCAGCTTCAAGTTGCCAGCGTGGACACCGTGTGGACCTGCGACTTCCGTCCCAGCG
AGCGCATTCATATTGCTGCTAAGCACGGCGAGGGTAACTACGTGGCGGACGCTGCAACCGTAGCTGCGCTGGAGGCCAAT
AATCGGGTCGTCTTCCGCTACACCGCTAATCCGAATGGATCGGTCCACGACATCGCTGGCATCACTAATGAGGCGGGCAA
CGTGGTCGGGCTCATGCCGCACCCGGAGCATTCTGTAGAGGAGCTCACCGGCGCCGGGACCGACGGGCTGGGATTCTTTC
GATCGTTAATGACATTCTTGTCCGCCCAGCTGTAG

Upstream 100 bases:

>100_bases
AGGGTTTGGAAGATCGTCTCGACGAGATCCGTCAGGTGGCCTCTGGGCTGTTGGCCAACACCGTCATTGAATCCTTCGAC
GTGCATGTGGAGGACTGACG

Downstream 100 bases:

>100_bases
CGGTGTTCGTCCTGGAGACGTACGGCGGGGTGGTCCTCATGGTCCACCCCGCCGTCAGGATTCTGCAGTGTTGTGGCTCA
CTGGGCGACGTGGATGCGCT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MVRIGVVTFPGTLDDQDAARAVRLAGAEPVSLWYASTDLAGVDAVILPGGFSYGDYLRAGALAAASPVMSSIRRAADGGL
PVLGICNGFQVLCESHLLPGTLMRNEKRRFHCSVQQLQVASVDTVWTCDFRPSERIHIAAKHGEGNYVADAATVAALEAN
NRVVFRYTANPNGSVHDIAGITNEAGNVVGLMPHPEHSVEELTGAGTDGLGFFRSLMTFLSAQL

Sequences:

>Translated_224_residues
MVRIGVVTFPGTLDDQDAARAVRLAGAEPVSLWYASTDLAGVDAVILPGGFSYGDYLRAGALAAASPVMSSIRRAADGGL
PVLGICNGFQVLCESHLLPGTLMRNEKRRFHCSVQQLQVASVDTVWTCDFRPSERIHIAAKHGEGNYVADAATVAALEAN
NRVVFRYTANPNGSVHDIAGITNEAGNVVGLMPHPEHSVEELTGAGTDGLGFFRSLMTFLSAQL
>Mature_224_residues
MVRIGVVTFPGTLDDQDAARAVRLAGAEPVSLWYASTDLAGVDAVILPGGFSYGDYLRAGALAAASPVMSSIRRAADGGL
PVLGICNGFQVLCESHLLPGTLMRNEKRRFHCSVQQLQVASVDTVWTCDFRPSERIHIAAKHGEGNYVADAATVAALEAN
NRVVFRYTANPNGSVHDIAGITNEAGNVVGLMPHPEHSVEELTGAGTDGLGFFRSLMTFLSAQL

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=184, Percent_Identity=34.7826086956522, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_PROAC (Q6A6B0)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056661.1
- ProteinModelPortal:   Q6A6B0
- SMR:   Q6A6B0
- GeneID:   2932701
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1987
- NMPDR:   fig|267747.1.peg.1938
- HOGENOM:   HBG302712
- OMA:   FPGTNCD
- ProtClustDB:   PRK03619
- BioCyc:   PACN267747:PPA1987-MONOMER
- BRENDA:   6.3.5.3
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 23710; Mature: 23710

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 86-86 ACT_SITE 194-194 ACT_SITE 196-196

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIGVVTFPGTLDDQDAARAVRLAGAEPVSLWYASTDLAGVDAVILPGGFSYGDYLRAG
CEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHH
ALAAASPVMSSIRRAADGGLPVLGICNGFQVLCESHLLPGTLMRNEKRRFHCSVQQLQVA
HHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHCCCCCCHHHCCCCHHEEECHHHEEEE
SVDTVWTCDFRPSERIHIAAKHGEGNYVADAATVAALEANNRVVFRYTANPNGSVHDIAG
CCCEEEEECCCCCCEEEEEEECCCCCEEEHHHEEEEEECCCEEEEEEECCCCCCEEECCC
ITNEAGNVVGLMPHPEHSVEELTGAGTDGLGFFRSLMTFLSAQL
CCCCCCCEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRIGVVTFPGTLDDQDAARAVRLAGAEPVSLWYASTDLAGVDAVILPGGFSYGDYLRAG
CEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHH
ALAAASPVMSSIRRAADGGLPVLGICNGFQVLCESHLLPGTLMRNEKRRFHCSVQQLQVA
HHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHCCCCCCHHHCCCCHHEEECHHHEEEE
SVDTVWTCDFRPSERIHIAAKHGEGNYVADAATVAALEANNRVVFRYTANPNGSVHDIAG
CCCEEEEECCCCCCEEEEEEECCCCCEEEHHHEEEEEECCCEEEEEEECCCCCCEEECCC
ITNEAGNVVGLMPHPEHSVEELTGAGTDGLGFFRSLMTFLSAQL
CCCCCCCEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA