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The map label for this gene is pepN [H]

Identifier: 50843426

GI number: 50843426

Start: 2147287

End: 2149821

Strand: Reverse

Name: pepN [H]

Synonym: PPA1979

Alternate gene names: 50843426

Gene position: 2149821-2147287 (Counterclockwise)

Preceding gene: 50843427

Following gene: 50843424

Centisome position: 83.97

GC content: 61.03

Gene sequence:

>2535_bases
ATGAATTTGACCCGCGAGGAAGCCCGTCACCGGTCTGAGATCATCAAAGTCGAGAGGTACCACGTCCGTATCGACGTACG
CGGTGCTGACGCTGATGGCGCCACCCACTTCACCTCCAACACCAGAGTGCGGTTCTCCACCACGGAGCCCGACACCTTCC
TGGACCTGCTCGACGGCGAGATCGAATCGGTCATCGTCAACGGCGAGGAAGTCGAGCCGGAATACGACGGATCGCGTATT
CAGCTGCACGGACTCCACACTCACCGCGAGAACCTCGTCATCGTCACCGCCAAGCTGCCCTATCAACACACTGGGCAGGG
CTTGCACCGCTTCGTCGACCCGGCCGACGGCAAGGTGTACCTCTACACCCACTTTGAGGCCGCCGACTCTCGCCGGATGT
ACTCAGTGTTCGAACAGCCCGATCTCAAAGCCCACGTCGACTTTGACGTCATCGCCCCGAGCGACTGGCGGGTCGCCTCC
AATCAGGTTCACGAAGACATTCGGGAGGAGGAAGATGGCCTCCTGCACGATTTCGCCCTCACCCCGAGGATGTCAACTTA
TCTCACCGCCATTGCTGCCGGCCCCTACGTCAGGTTCCAAGACGAGTGGCACTCTCGTGACGGCTCCGAATCGATTCCGC
TGGGTATCTTGGCTCGTGCCTCGCTGGCCGAGTACGTCGACCATGAGGAGATCTTCAAGATCACCAAGCAGGGTTTGGCC
TTCTACCATCGCACCTTTGGCTACCCCTACCCATGGGGTAAGTACGACCAGATTTTCGTGCCGGAATACAACCTTGGTGC
GATGGAGAATCCGGGTTTGGTGACCTTCACCGAGAACTACATCCATCGCGGCCCAGCTACTCGATCTGAGCTTGCAGGTC
GCACCAACACCATCCTCCACGAGATGGCTCACATGTGGTTCGGCGACCTCGTTACCCCGAAGTGGTGGGACGATCTGTGG
CTTAAGGAGTCCTTCGCCGAGTACATGGGTGCCCACGCCTCGGTTGCCGGCACCGAATACCGCGAGGCTTGGACGAACTT
CGCCGTCGGGCGCAAAGCCTGGGCCTACACCGCCGACCAGCAGTCGACAACCCACCCGATCGTCGCTGATATCGTCGATC
TGGAAGCTGCCCGTCAGAACTTCGACGGCATTACCTATGCCAAAGGCGCCTCGGTGCTCAAGCAGTTGGTGGCCCATGTC
GGTGTTGAGCGGTTCTTTAGCGCGGCCCGCCACTACTTTCGTGAATTGGCCTTCTCATCAGCCACCCTTGACGACCTCAT
TCGTCACCTCGAAAAGGCCTGCGGACGTGATCTGAGCGCCTGGGTCGACGCTTGGCTTAAGACTGCTGGTCCCGACGTCC
TGCTGCCGGAACTTACTATCAGTGACGGCGTTGTTTCCGAGCTGGCTGTCGTGCGTGACTCGATTGACGTCCGCACCGGC
CGCGACGTCAATCGTCCCCACACCCTGCGCGTCGGGCTGTACTCCTTGCACGGCGAAGATTTGGTGCGCACTAACCTCAT
CGACCTCACTATCTCCTCCCCACGCACCCCGGTTCCTGAGGCGGCGGGCAAACCGGCCCCCGACCTCATCCTCATCAACG
ACGACGATCTCACGTACGCCAAGGTGCGTCTTGGCGCTACTGGTACGAAGACCGTCCTTGCTCACCTGTCGGGTCTGGCC
GACCCATTGGCTCGCGCTCTGGTCTGGTCGATGCTGTGGAACTCCGTGCGCGACGCCAAGCTTAAGGTTCAGGATTACCT
TGACGCCGTTGCTGCGCATGGTCCCAAAGAGACCGAACCGGCCATCCTCGCCACCGTATTGCAGCAGCTACGAATGGCCG
TCGAGAACTATCTTCCTGATTCTGCTCGCAAGACCGCACGGCGCGCCGAGGCAGCCCGGGCCTGGCAGGGACTCGACGAG
TCCGAGCTGGGTAGCGACCTACAGCGCTTGTGGGCGCGTCACGCCCTGGCCTTGTCAGCTACCGATCCGGACTCGGCTGG
ACGGGTTCGTGGCCTGCTTGACGGCAATGTCGCCGGCCTGGTCGTCGATCCAGAAATGAGGTGGCAGTCCTGGATGGCTC
TGGCCGCTCTGGGCCAGGCTAGCGTCGAAGACCTGGATGCCGAGCTAGAGCGTGACCACACCAAGACCGGTGTTGCCCAT
CACATGGCGGCCCTCACCGCTCGTCCTGACGATGCCGCGAAGCAGGAGGCTTATCGTCGCCTGCGCACCCTGGGAGAGCT
GTCCAATGAGCACTGTCTGGCCCTCATCGAGGGTTTGCGTACCCCGCTGGGTGCCCAGACGTTTGCCAATCTCAATGGCT
CCTACTTCGATGATCTTGAGCAGATCTGGCAGGAGTTCCCGATCGAGATGGCCCAGCGTTTAGTCGTCGGGCTGTTCCCT
GACGGTGATACCGCCGAGACTGCTGACCGTTGGTTGGCGAGTCACCAATCGGCCACTGGCGGTCTGACCCGGATGGTTAG
GGAACGTCGCGACGCGGCATCTCGTGCCGAAACCGCCCGTGATTTCAATAGCTGA

Upstream 100 bases:

>100_bases
GACACCCTGGTCGAGCCGGGGCGCAGCTTCACCGGGAGGAACTGCTCAGTCTGGATGCTCATGGCATGCGCCACTGCCAT
ACTCTGGTGGTGTGAGTTCG

Downstream 100 bases:

>100_bases
GTAACGGCTTTAACGGCGACGCTGTTTGACGACCCGCCACTGCCGTGCCAAGGCCTCACGCCAGGTAGGCACGGTGACGC
CGTTGTCAGCCATGATCTGG

Product: aminopeptidase N

Products: NA

Alternate protein names: Alanine aminopeptidase; Lysyl aminopeptidase; Lys-AP [H]

Number of amino acids: Translated: 844; Mature: 844

Protein sequence:

>844_residues
MNLTREEARHRSEIIKVERYHVRIDVRGADADGATHFTSNTRVRFSTTEPDTFLDLLDGEIESVIVNGEEVEPEYDGSRI
QLHGLHTHRENLVIVTAKLPYQHTGQGLHRFVDPADGKVYLYTHFEAADSRRMYSVFEQPDLKAHVDFDVIAPSDWRVAS
NQVHEDIREEEDGLLHDFALTPRMSTYLTAIAAGPYVRFQDEWHSRDGSESIPLGILARASLAEYVDHEEIFKITKQGLA
FYHRTFGYPYPWGKYDQIFVPEYNLGAMENPGLVTFTENYIHRGPATRSELAGRTNTILHEMAHMWFGDLVTPKWWDDLW
LKESFAEYMGAHASVAGTEYREAWTNFAVGRKAWAYTADQQSTTHPIVADIVDLEAARQNFDGITYAKGASVLKQLVAHV
GVERFFSAARHYFRELAFSSATLDDLIRHLEKACGRDLSAWVDAWLKTAGPDVLLPELTISDGVVSELAVVRDSIDVRTG
RDVNRPHTLRVGLYSLHGEDLVRTNLIDLTISSPRTPVPEAAGKPAPDLILINDDDLTYAKVRLGATGTKTVLAHLSGLA
DPLARALVWSMLWNSVRDAKLKVQDYLDAVAAHGPKETEPAILATVLQQLRMAVENYLPDSARKTARRAEAARAWQGLDE
SELGSDLQRLWARHALALSATDPDSAGRVRGLLDGNVAGLVVDPEMRWQSWMALAALGQASVEDLDAELERDHTKTGVAH
HMAALTARPDDAAKQEAYRRLRTLGELSNEHCLALIEGLRTPLGAQTFANLNGSYFDDLEQIWQEFPIEMAQRLVVGLFP
DGDTAETADRWLASHQSATGGLTRMVRERRDAASRAETARDFNS

Sequences:

>Translated_844_residues
MNLTREEARHRSEIIKVERYHVRIDVRGADADGATHFTSNTRVRFSTTEPDTFLDLLDGEIESVIVNGEEVEPEYDGSRI
QLHGLHTHRENLVIVTAKLPYQHTGQGLHRFVDPADGKVYLYTHFEAADSRRMYSVFEQPDLKAHVDFDVIAPSDWRVAS
NQVHEDIREEEDGLLHDFALTPRMSTYLTAIAAGPYVRFQDEWHSRDGSESIPLGILARASLAEYVDHEEIFKITKQGLA
FYHRTFGYPYPWGKYDQIFVPEYNLGAMENPGLVTFTENYIHRGPATRSELAGRTNTILHEMAHMWFGDLVTPKWWDDLW
LKESFAEYMGAHASVAGTEYREAWTNFAVGRKAWAYTADQQSTTHPIVADIVDLEAARQNFDGITYAKGASVLKQLVAHV
GVERFFSAARHYFRELAFSSATLDDLIRHLEKACGRDLSAWVDAWLKTAGPDVLLPELTISDGVVSELAVVRDSIDVRTG
RDVNRPHTLRVGLYSLHGEDLVRTNLIDLTISSPRTPVPEAAGKPAPDLILINDDDLTYAKVRLGATGTKTVLAHLSGLA
DPLARALVWSMLWNSVRDAKLKVQDYLDAVAAHGPKETEPAILATVLQQLRMAVENYLPDSARKTARRAEAARAWQGLDE
SELGSDLQRLWARHALALSATDPDSAGRVRGLLDGNVAGLVVDPEMRWQSWMALAALGQASVEDLDAELERDHTKTGVAH
HMAALTARPDDAAKQEAYRRLRTLGELSNEHCLALIEGLRTPLGAQTFANLNGSYFDDLEQIWQEFPIEMAQRLVVGLFP
DGDTAETADRWLASHQSATGGLTRMVRERRDAASRAETARDFNS
>Mature_844_residues
MNLTREEARHRSEIIKVERYHVRIDVRGADADGATHFTSNTRVRFSTTEPDTFLDLLDGEIESVIVNGEEVEPEYDGSRI
QLHGLHTHRENLVIVTAKLPYQHTGQGLHRFVDPADGKVYLYTHFEAADSRRMYSVFEQPDLKAHVDFDVIAPSDWRVAS
NQVHEDIREEEDGLLHDFALTPRMSTYLTAIAAGPYVRFQDEWHSRDGSESIPLGILARASLAEYVDHEEIFKITKQGLA
FYHRTFGYPYPWGKYDQIFVPEYNLGAMENPGLVTFTENYIHRGPATRSELAGRTNTILHEMAHMWFGDLVTPKWWDDLW
LKESFAEYMGAHASVAGTEYREAWTNFAVGRKAWAYTADQQSTTHPIVADIVDLEAARQNFDGITYAKGASVLKQLVAHV
GVERFFSAARHYFRELAFSSATLDDLIRHLEKACGRDLSAWVDAWLKTAGPDVLLPELTISDGVVSELAVVRDSIDVRTG
RDVNRPHTLRVGLYSLHGEDLVRTNLIDLTISSPRTPVPEAAGKPAPDLILINDDDLTYAKVRLGATGTKTVLAHLSGLA
DPLARALVWSMLWNSVRDAKLKVQDYLDAVAAHGPKETEPAILATVLQQLRMAVENYLPDSARKTARRAEAARAWQGLDE
SELGSDLQRLWARHALALSATDPDSAGRVRGLLDGNVAGLVVDPEMRWQSWMALAALGQASVEDLDAELERDHTKTGVAH
HMAALTARPDDAAKQEAYRRLRTLGELSNEHCLALIEGLRTPLGAQTFANLNGSYFDDLEQIWQEFPIEMAQRLVVGLFP
DGDTAETADRWLASHQSATGGLTRMVRERRDAASRAETARDFNS

Specific function: Aminopeptidase with broad substrate specificity to several peptides. Shows strong preference for leucine but cleaves also next to Arg and lysine in peptide-bond-containing substrates [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=435, Percent_Identity=28.735632183908, Blast_Score=167, Evalue=5e-41,
Organism=Homo sapiens, GI157266300, Length=331, Percent_Identity=31.7220543806647, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI194306629, Length=326, Percent_Identity=30.6748466257669, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI11641261, Length=326, Percent_Identity=30.6748466257669, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI61742777, Length=322, Percent_Identity=29.8136645962733, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI310123622, Length=309, Percent_Identity=30.42071197411, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI61742775, Length=322, Percent_Identity=29.8136645962733, Blast_Score=141, Evalue=3e-33,
Organism=Homo sapiens, GI132814467, Length=359, Percent_Identity=27.8551532033426, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI7019561, Length=362, Percent_Identity=29.0055248618785, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI94818891, Length=318, Percent_Identity=29.2452830188679, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI94818901, Length=318, Percent_Identity=29.2452830188679, Blast_Score=138, Evalue=3e-32,
Organism=Homo sapiens, GI310133497, Length=309, Percent_Identity=29.7734627831715, Blast_Score=133, Evalue=8e-31,
Organism=Homo sapiens, GI194239713, Length=402, Percent_Identity=25.8706467661692, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI4505029, Length=448, Percent_Identity=25.2232142857143, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI40316915, Length=363, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI54020718, Length=305, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1787163, Length=304, Percent_Identity=28.2894736842105, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115533278, Length=366, Percent_Identity=29.7814207650273, Blast_Score=153, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI115533276, Length=366, Percent_Identity=29.7814207650273, Blast_Score=152, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI71989071, Length=394, Percent_Identity=28.4263959390863, Blast_Score=152, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI71989076, Length=394, Percent_Identity=28.4263959390863, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71990873, Length=353, Percent_Identity=31.4447592067989, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17565628, Length=352, Percent_Identity=27.5568181818182, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17569221, Length=328, Percent_Identity=30.7926829268293, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI133903840, Length=317, Percent_Identity=29.0220820189274, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17569225, Length=306, Percent_Identity=26.4705882352941, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI193206928, Length=379, Percent_Identity=26.6490765171504, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193206926, Length=379, Percent_Identity=26.6490765171504, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17544504, Length=397, Percent_Identity=24.4332493702771, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71984339, Length=344, Percent_Identity=24.1279069767442, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71984353, Length=344, Percent_Identity=24.1279069767442, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71993840, Length=218, Percent_Identity=28.8990825688073, Blast_Score=73, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI9755335, Length=345, Percent_Identity=29.8550724637681, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6321837, Length=403, Percent_Identity=28.7841191066998, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6322054, Length=366, Percent_Identity=22.6775956284153, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324283, Length=308, Percent_Identity=24.3506493506494, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161078673, Length=370, Percent_Identity=29.7297297297297, Blast_Score=159, Evalue=9e-39,
Organism=Drosophila melanogaster, GI28571901, Length=370, Percent_Identity=29.7297297297297, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24655252, Length=343, Percent_Identity=32.0699708454811, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24655274, Length=343, Percent_Identity=32.0699708454811, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24655260, Length=343, Percent_Identity=32.0699708454811, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24655265, Length=343, Percent_Identity=32.0699708454811, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24655268, Length=343, Percent_Identity=32.0699708454811, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24655257, Length=343, Percent_Identity=32.0699708454811, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24650973, Length=428, Percent_Identity=29.9065420560748, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45550850, Length=428, Percent_Identity=29.9065420560748, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21358341, Length=461, Percent_Identity=29.0672451193059, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24651025, Length=353, Percent_Identity=29.7450424929178, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24651023, Length=353, Percent_Identity=29.7450424929178, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24651021, Length=353, Percent_Identity=29.7450424929178, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24646514, Length=360, Percent_Identity=31.9444444444444, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI221379089, Length=349, Percent_Identity=30.0859598853868, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646516, Length=350, Percent_Identity=32, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24646510, Length=352, Percent_Identity=29.5454545454545, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24646518, Length=350, Percent_Identity=32, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24646512, Length=352, Percent_Identity=29.5454545454545, Blast_Score=140, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24651016, Length=430, Percent_Identity=28.1395348837209, Blast_Score=133, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281362224, Length=322, Percent_Identity=27.9503105590062, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI221458256, Length=322, Percent_Identity=27.9503105590062, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI221330574, Length=349, Percent_Identity=28.080229226361, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24648786, Length=360, Percent_Identity=26.9444444444444, Blast_Score=109, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24648790, Length=327, Percent_Identity=27.5229357798165, Blast_Score=109, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571792, Length=337, Percent_Identity=26.7062314540059, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648784, Length=305, Percent_Identity=23.6065573770492, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281362221, Length=298, Percent_Identity=24.1610738255034, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24584504, Length=348, Percent_Identity=25.2873563218391, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24641062, Length=324, Percent_Identity=24.0740740740741, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24585062, Length=381, Percent_Identity=26.246719160105, Blast_Score=70, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24585064, Length=381, Percent_Identity=26.246719160105, Blast_Score=70, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24585066, Length=381, Percent_Identity=26.246719160105, Blast_Score=70, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45550350, Length=377, Percent_Identity=25.9946949602122, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012778
- InterPro:   IPR001930
- InterPro:   IPR014782 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 94400; Mature: 94400

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTREEARHRSEIIKVERYHVRIDVRGADADGATHFTSNTRVRFSTTEPDTFLDLLDGE
CCCCHHHHHHHHHHEEEEEEEEEEEEECCCCCCCCEECCCCEEEEECCCCHHHHHHHCCC
IESVIVNGEEVEPEYDGSRIQLHGLHTHRENLVIVTAKLPYQHTGQGLHRFVDPADGKVY
CCEEEECCCCCCCCCCCCEEEEEEEEECCCCEEEEEEECCCHHCCCHHHHHCCCCCCEEE
LYTHFEAADSRRMYSVFEQPDLKAHVDFDVIAPSDWRVASNQVHEDIREEEDGLLHDFAL
EEEEECCCCCHHHHHHHCCCCCEEECCEEEECCCCCCHHHHHHHHHHHHHHCCCEEHHCC
TPRMSTYLTAIAAGPYVRFQDEWHSRDGSESIPLGILARASLAEYVDHEEIFKITKQGLA
CCCHHHHHHHHHCCCCEEECHHHCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHH
FYHRTFGYPYPWGKYDQIFVPEYNLGAMENPGLVTFTENYIHRGPATRSELAGRTNTILH
HHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEHHHHHCCCCCHHHHCCHHHHHHH
EMAHMWFGDLVTPKWWDDLWLKESFAEYMGAHASVAGTEYREAWTNFAVGRKAWAYTADQ
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHEEEECCC
QSTTHPIVADIVDLEAARQNFDGITYAKGASVLKQLVAHVGVERFFSAARHYFRELAFSS
CCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ATLDDLIRHLEKACGRDLSAWVDAWLKTAGPDVLLPELTISDGVVSELAVVRDSIDVRTG
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCC
RDVNRPHTLRVGLYSLHGEDLVRTNLIDLTISSPRTPVPEAAGKPAPDLILINDDDLTYA
CCCCCCCEEEEEEEEECCCHHHHHEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCEEE
KVRLGATGTKTVLAHLSGLADPLARALVWSMLWNSVRDAKLKVQDYLDAVAAHGPKETEP
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AILATVLQQLRMAVENYLPDSARKTARRAEAARAWQGLDESELGSDLQRLWARHALALSA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEC
TDPDSAGRVRGLLDGNVAGLVVDPEMRWQSWMALAALGQASVEDLDAELERDHTKTGVAH
CCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
HMAALTARPDDAAKQEAYRRLRTLGELSNEHCLALIEGLRTPLGAQTFANLNGSYFDDLE
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHH
QIWQEFPIEMAQRLVVGLFPDGDTAETADRWLASHQSATGGLTRMVRERRDAASRAETAR
HHHHHCCHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
DFNS
CCCC
>Mature Secondary Structure
MNLTREEARHRSEIIKVERYHVRIDVRGADADGATHFTSNTRVRFSTTEPDTFLDLLDGE
CCCCHHHHHHHHHHEEEEEEEEEEEEECCCCCCCCEECCCCEEEEECCCCHHHHHHHCCC
IESVIVNGEEVEPEYDGSRIQLHGLHTHRENLVIVTAKLPYQHTGQGLHRFVDPADGKVY
CCEEEECCCCCCCCCCCCEEEEEEEEECCCCEEEEEEECCCHHCCCHHHHHCCCCCCEEE
LYTHFEAADSRRMYSVFEQPDLKAHVDFDVIAPSDWRVASNQVHEDIREEEDGLLHDFAL
EEEEECCCCCHHHHHHHCCCCCEEECCEEEECCCCCCHHHHHHHHHHHHHHCCCEEHHCC
TPRMSTYLTAIAAGPYVRFQDEWHSRDGSESIPLGILARASLAEYVDHEEIFKITKQGLA
CCCHHHHHHHHHCCCCEEECHHHCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHH
FYHRTFGYPYPWGKYDQIFVPEYNLGAMENPGLVTFTENYIHRGPATRSELAGRTNTILH
HHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEHHHHHCCCCCHHHHCCHHHHHHH
EMAHMWFGDLVTPKWWDDLWLKESFAEYMGAHASVAGTEYREAWTNFAVGRKAWAYTADQ
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHEEEECCC
QSTTHPIVADIVDLEAARQNFDGITYAKGASVLKQLVAHVGVERFFSAARHYFRELAFSS
CCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ATLDDLIRHLEKACGRDLSAWVDAWLKTAGPDVLLPELTISDGVVSELAVVRDSIDVRTG
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCC
RDVNRPHTLRVGLYSLHGEDLVRTNLIDLTISSPRTPVPEAAGKPAPDLILINDDDLTYA
CCCCCCCEEEEEEEEECCCHHHHHEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCEEE
KVRLGATGTKTVLAHLSGLADPLARALVWSMLWNSVRDAKLKVQDYLDAVAAHGPKETEP
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AILATVLQQLRMAVENYLPDSARKTARRAEAARAWQGLDESELGSDLQRLWARHALALSA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEC
TDPDSAGRVRGLLDGNVAGLVVDPEMRWQSWMALAALGQASVEDLDAELERDHTKTGVAH
CCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
HMAALTARPDDAAKQEAYRRLRTLGELSNEHCLALIEGLRTPLGAQTFANLNGSYFDDLE
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHH
QIWQEFPIEMAQRLVVGLFPDGDTAETADRWLASHQSATGGLTRMVRERRDAASRAETAR
HHHHHCCHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
DFNS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7909302; 7765336 [H]