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The map label for this gene is pab [H]

Identifier: 50843423

GI number: 50843423

Start: 2141513

End: 2143600

Strand: Direct

Name: pab [H]

Synonym: PPA1976

Alternate gene names: 50843423

Gene position: 2141513-2143600 (Clockwise)

Preceding gene: 50843410

Following gene: 50843425

Centisome position: 83.64

GC content: 62.21

Gene sequence:

>2088_bases
GTGATCCTGCTGGTTGACAACCACGATTCCTTCACCTTCAACCTGGCACACCTATTGGCCGAAGTCAGCGGGATCGAGCC
AGTGGTGGTCCGCCCCGAGGAGGTCGAGCGTGCAGGGATCCTCCGCCGACTGGCTGATGGCGAATTCGACCACGTGGTTA
TCGGTCCAGGACCTGGCTCCCCGCACAACGACAAGGACTTCAAGACCGCCGGACAGGTGATCGATGCCTCCAACAAGCTC
CCCCTGCTCGGGGTGTGCCTGGGCCACCAAGGCCTCGGGTTACGTCACGGTGCCCAGTTGCAGACCATTCGGCCCCATCA
CGGCATCGTCAGCCGAATTCATCACTCCAGGCGCGGAATCTTCGCCGGATTACCGCAAGATTTCGAGGCAACTCGGTATC
ACTCACTGTGCTTGACCACGTTGGGTGACCAGATCGTCGAACATGCTCGCGCCGAGGATGGCGCCATCATGGCGTTCGAG
GTTGCCGACCGGCCACACTGGGGCGTGCAATTCCACCCAGAGTCAGTCATGACGCAGGTCGGATGTCAGTTAATGACGAA
CTTCCTGGCGATCGGCAGCCAGCCACGACACAGCGAGGTACGCGACAAACGCGAACCGCGCAACATCCAGTCACGAAAGT
GTGCCCGGACTACGGCACGGTGGACAATCCACCACCAAACGGTGGACATCGACCTCGACGAAGAAGCCACCTTCAGCCGC
CTCGCTGGCGACGGTGACGCCTTCTGGTTGGACTCGGCCACCACGCGTGGCGACACCGGCCGTTGGAGTGTCATGGGCAC
GGCGTCGGGGGCGGCATCCGAACTGGTCAGTTACGACGTCATCACAAACACGTTGACGGTCAACGGGCGAACCCAGTCTG
GTGATGTGCTGGACTTCTTGGAACGCCGTCTTGCAGATGGAGTATCACGGAGGGACCCGGAACTAGATGACATCCCATTC
ACAGGTGGCTATGTCGGTTTCCTGGGCTATGAGTGCAAGGCGCTGACCTTGGGCCCGAATGCGCACTGCAGCGAACTGCC
CGATGCCATGTGGATGCGTCCGGCCAGCTGGATTGCGTACGACCACTACCGGCATCACGCTCACCTCCTAGCCTTGGACG
ACCGTGACACGCCCGGCTGCAATGAGGCCGCTGATCTATTGGACGCACTGGCTGCGACGCTGGTGAAGCGACCAGGTAGC
AGCGAAGAGCCCGCACCGCTAACCGTGCCTGTGGAAGGGTCGTGGCGGCTCAGCCGAGGGGGCTACCAGGACCGTGTTGC
CGCAATCCAGCAGGCGCTAACGCGCGGTGACTCGTACGAGGCCTGTCTGACCGACACGTGGACCTCCCGGTGCGACGTGG
ACGGCTGGCGGTTGTACCGCGCACTGCGGCGTCGAAACCCAGCCCCCTATGGGGCGTATCTTCGGTTTACCGACCCGCGT
GTGGAGGTGTGCTCTTCATCCCCGGAACGGTTCCTGCGAGTACGCGACGGCATCGCTGAATCCAAGCCGATCAAGGGGAC
AATGGCTCGCTGTGATGATCCGGTGGAGGATGCCCGGGGAATTGTCGATTTACAACATGACGCGAAAAACCGCGCCGAGA
ATCTCATGATCGCTGATCTGGTGCGCAACGACCTGTCGCGCGTGTGCCAACCAGGCACGGTGGAGGTACCACGTCTGATG
GCGATCGAGTCATATGCGACGGTGCACCAGATGGTGACCACGGTGCGCGGACGATTGCGTGAGGACGTCGGATTGGTCGA
CGTACTGCGAGCGACCTTCCCTGGTGGATCGATGACCGGGGCACCGAAGGAACGGTCCGTAGAAATCCTGGACGGTCTGG
AGGTCGGCGCCCGGGGAATCTACTCGGGAATCCTGGGATATCTCGGCTTCGATCGCACCGCCGACCTCAGCATCGTGATA
CGGACGGTGATCCGAACGGGGTCGCAGGTAACGGTCGGTGCCGGCGGCGCAATCGTCGCAGCTTCCCAGCCTGACGAGGA
GTGGCGCGAGAAGAACCTCAAAGCGGCGGCACCGTTGGCTGCGCTGACGCTGTCAGCCGGGCCAGGAATTCCCGTCACTC
CCCCATAG

Upstream 100 bases:

>100_bases
CCCTACCACGGCACGATGCCAGGACAGCCCGTTTCGGGAAGCGCCCCCTATCCTTGTGCTATTGCTCTTGCACTGCAGCG
GATGTCACCGAGGAGGGCCC

Downstream 100 bases:

>100_bases
CAGTTGGAATCGGCTTGCGCCAGGCTCGTTCGATCTCGTCAAGGGGGAGGCTGAACAGACCGTTAACCTCGATCTCACCG
TGATCTATGACCTCGCCAAT

Product: para-aminobenzoate synthase

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MILLVDNHDSFTFNLAHLLAEVSGIEPVVVRPEEVERAGILRRLADGEFDHVVIGPGPGSPHNDKDFKTAGQVIDASNKL
PLLGVCLGHQGLGLRHGAQLQTIRPHHGIVSRIHHSRRGIFAGLPQDFEATRYHSLCLTTLGDQIVEHARAEDGAIMAFE
VADRPHWGVQFHPESVMTQVGCQLMTNFLAIGSQPRHSEVRDKREPRNIQSRKCARTTARWTIHHQTVDIDLDEEATFSR
LAGDGDAFWLDSATTRGDTGRWSVMGTASGAASELVSYDVITNTLTVNGRTQSGDVLDFLERRLADGVSRRDPELDDIPF
TGGYVGFLGYECKALTLGPNAHCSELPDAMWMRPASWIAYDHYRHHAHLLALDDRDTPGCNEAADLLDALAATLVKRPGS
SEEPAPLTVPVEGSWRLSRGGYQDRVAAIQQALTRGDSYEACLTDTWTSRCDVDGWRLYRALRRRNPAPYGAYLRFTDPR
VEVCSSSPERFLRVRDGIAESKPIKGTMARCDDPVEDARGIVDLQHDAKNRAENLMIADLVRNDLSRVCQPGTVEVPRLM
AIESYATVHQMVTTVRGRLREDVGLVDVLRATFPGGSMTGAPKERSVEILDGLEVGARGIYSGILGYLGFDRTADLSIVI
RTVIRTGSQVTVGAGGAIVAASQPDEEWREKNLKAAAPLAALTLSAGPGIPVTPP

Sequences:

>Translated_695_residues
MILLVDNHDSFTFNLAHLLAEVSGIEPVVVRPEEVERAGILRRLADGEFDHVVIGPGPGSPHNDKDFKTAGQVIDASNKL
PLLGVCLGHQGLGLRHGAQLQTIRPHHGIVSRIHHSRRGIFAGLPQDFEATRYHSLCLTTLGDQIVEHARAEDGAIMAFE
VADRPHWGVQFHPESVMTQVGCQLMTNFLAIGSQPRHSEVRDKREPRNIQSRKCARTTARWTIHHQTVDIDLDEEATFSR
LAGDGDAFWLDSATTRGDTGRWSVMGTASGAASELVSYDVITNTLTVNGRTQSGDVLDFLERRLADGVSRRDPELDDIPF
TGGYVGFLGYECKALTLGPNAHCSELPDAMWMRPASWIAYDHYRHHAHLLALDDRDTPGCNEAADLLDALAATLVKRPGS
SEEPAPLTVPVEGSWRLSRGGYQDRVAAIQQALTRGDSYEACLTDTWTSRCDVDGWRLYRALRRRNPAPYGAYLRFTDPR
VEVCSSSPERFLRVRDGIAESKPIKGTMARCDDPVEDARGIVDLQHDAKNRAENLMIADLVRNDLSRVCQPGTVEVPRLM
AIESYATVHQMVTTVRGRLREDVGLVDVLRATFPGGSMTGAPKERSVEILDGLEVGARGIYSGILGYLGFDRTADLSIVI
RTVIRTGSQVTVGAGGAIVAASQPDEEWREKNLKAAAPLAALTLSAGPGIPVTPP
>Mature_695_residues
MILLVDNHDSFTFNLAHLLAEVSGIEPVVVRPEEVERAGILRRLADGEFDHVVIGPGPGSPHNDKDFKTAGQVIDASNKL
PLLGVCLGHQGLGLRHGAQLQTIRPHHGIVSRIHHSRRGIFAGLPQDFEATRYHSLCLTTLGDQIVEHARAEDGAIMAFE
VADRPHWGVQFHPESVMTQVGCQLMTNFLAIGSQPRHSEVRDKREPRNIQSRKCARTTARWTIHHQTVDIDLDEEATFSR
LAGDGDAFWLDSATTRGDTGRWSVMGTASGAASELVSYDVITNTLTVNGRTQSGDVLDFLERRLADGVSRRDPELDDIPF
TGGYVGFLGYECKALTLGPNAHCSELPDAMWMRPASWIAYDHYRHHAHLLALDDRDTPGCNEAADLLDALAATLVKRPGS
SEEPAPLTVPVEGSWRLSRGGYQDRVAAIQQALTRGDSYEACLTDTWTSRCDVDGWRLYRALRRRNPAPYGAYLRFTDPR
VEVCSSSPERFLRVRDGIAESKPIKGTMARCDDPVEDARGIVDLQHDAKNRAENLMIADLVRNDLSRVCQPGTVEVPRLM
AIESYATVHQMVTTVRGRLREDVGLVDVLRATFPGGSMTGAPKERSVEILDGLEVGARGIYSGILGYLGFDRTADLSIVI
RTVIRTGSQVTVGAGGAIVAASQPDEEWREKNLKAAAPLAALTLSAGPGIPVTPP

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=430, Percent_Identity=34.6511627906977, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787518, Length=266, Percent_Identity=31.9548872180451, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789760, Length=193, Percent_Identity=36.7875647668394, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787517, Length=209, Percent_Identity=34.9282296650718, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI87082077, Length=214, Percent_Identity=27.1028037383178, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786809, Length=237, Percent_Identity=24.4725738396624, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324361, Length=788, Percent_Identity=28.6802030456853, Blast_Score=248, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6320935, Length=497, Percent_Identity=26.1569416498994, Blast_Score=170, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6322638, Length=193, Percent_Identity=32.6424870466321, Blast_Score=94, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 76015; Mature: 76015

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLVDNHDSFTFNLAHLLAEVSGIEPVVVRPEEVERAGILRRLADGEFDHVVIGPGPGS
CEEEEECCCCEEHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCCCCEEEECCCCCC
PHNDKDFKTAGQVIDASNKLPLLGVCLGHQGLGLRHGAQLQTIRPHHGIVSRIHHSRRGI
CCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCC
FAGLPQDFEATRYHSLCLTTLGDQIVEHARAEDGAIMAFEVADRPHWGVQFHPESVMTQV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECHHHHHHHH
GCQLMTNFLAIGSQPRHSEVRDKREPRNIQSRKCARTTARWTIHHQTVDIDLDEEATFSR
HHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHEEEEEEEEEEEEECCCCHHHHH
LAGDGDAFWLDSATTRGDTGRWSVMGTASGAASELVSYDVITNTLTVNGRTQSGDVLDFL
HCCCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHEEEEEEEEECCCCCCCHHHHHH
ERRLADGVSRRDPELDDIPFTGGYVGFLGYECKALTLGPNAHCSELPDAMWMRPASWIAY
HHHHHCCHHHCCCCCCCCCCCCCCCEEECCEEEEEEECCCCCHHHCCHHHHCCCCHHHHH
DHYRHHAHLLALDDRDTPGCNEAADLLDALAATLVKRPGSSEEPAPLTVPVEGSWRLSRG
HHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEECCC
GYQDRVAAIQQALTRGDSYEACLTDTWTSRCDVDGWRLYRALRRRNPAPYGAYLRFTDPR
CHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCH
VEVCSSSPERFLRVRDGIAESKPIKGTMARCDDPVEDARGIVDLQHDAKNRAENLMIADL
HHHHCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHCCEEEEHHHHHHHHHHHHHHHH
VRNDLSRVCQPGTVEVPRLMAIESYATVHQMVTTVRGRLREDVGLVDVLRATFPGGSMTG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
APKERSVEILDGLEVGARGIYSGILGYLGFDRTADLSIVIRTVIRTGSQVTVGAGGAIVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEE
ASQPDEEWREKNLKAAAPLAALTLSAGPGIPVTPP
CCCCCHHHHHCCCCHHCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MILLVDNHDSFTFNLAHLLAEVSGIEPVVVRPEEVERAGILRRLADGEFDHVVIGPGPGS
CEEEEECCCCEEHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCCCCEEEECCCCCC
PHNDKDFKTAGQVIDASNKLPLLGVCLGHQGLGLRHGAQLQTIRPHHGIVSRIHHSRRGI
CCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCC
FAGLPQDFEATRYHSLCLTTLGDQIVEHARAEDGAIMAFEVADRPHWGVQFHPESVMTQV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECHHHHHHHH
GCQLMTNFLAIGSQPRHSEVRDKREPRNIQSRKCARTTARWTIHHQTVDIDLDEEATFSR
HHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHEEEEEEEEEEEEECCCCHHHHH
LAGDGDAFWLDSATTRGDTGRWSVMGTASGAASELVSYDVITNTLTVNGRTQSGDVLDFL
HCCCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHEEEEEEEEECCCCCCCHHHHHH
ERRLADGVSRRDPELDDIPFTGGYVGFLGYECKALTLGPNAHCSELPDAMWMRPASWIAY
HHHHHCCHHHCCCCCCCCCCCCCCCEEECCEEEEEEECCCCCHHHCCHHHHCCCCHHHHH
DHYRHHAHLLALDDRDTPGCNEAADLLDALAATLVKRPGSSEEPAPLTVPVEGSWRLSRG
HHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEECCC
GYQDRVAAIQQALTRGDSYEACLTDTWTSRCDVDGWRLYRALRRRNPAPYGAYLRFTDPR
CHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCH
VEVCSSSPERFLRVRDGIAESKPIKGTMARCDDPVEDARGIVDLQHDAKNRAENLMIADL
HHHHCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHCCEEEEHHHHHHHHHHHHHHHH
VRNDLSRVCQPGTVEVPRLMAIESYATVHQMVTTVRGRLREDVGLVDVLRATFPGGSMTG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
APKERSVEILDGLEVGARGIYSGILGYLGFDRTADLSIVIRTVIRTGSQVTVGAGGAIVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEE
ASQPDEEWREKNLKAAAPLAALTLSAGPGIPVTPP
CCCCCHHHHHCCCCHHCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]