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The map label for this gene is ybbK [C]

Identifier: 50843420

GI number: 50843420

Start: 2137463

End: 2138230

Strand: Reverse

Name: ybbK [C]

Synonym: PPA1973

Alternate gene names: 50843420

Gene position: 2138230-2137463 (Counterclockwise)

Preceding gene: 50843421

Following gene: 50843419

Centisome position: 83.52

GC content: 61.33

Gene sequence:

>768_bases
ATGAGTGATCTCGAATGGACCTTCACCACGATCGCGCTCGTCATCCTCGTCATCGGGTTCCTGATATCGAGCTTCAAGAT
CATCCCCGAATATGAGCGCGGCGTCGTTTTCCGGCTCGGCAAACTGCGCGGGCTGCACGGTTCCGGGCTCGTGTTTATCT
TCCCCGGCCTCGACAAGCTGCACAGAGTCGACCAACGCACCGTAACCCTGACGATCCCGCCGCAGGAGATCATCACCCGT
GACAACGTGCCGGCTCGTGTCAACGCCGTCGTCCTATTCAACGTGACGGACCCCATGGATGCTGTCATGAATGTGGAGAA
TTACGCGATCGCGACGAGCCAGATCGCTCAGACGACGTTGCGAAGTGTCCTAGGCCGGGCGGATCTCGACACCCTCCTCG
CCCACCGGGAGGAACTCAACACGGACCTCCGTGAGATCATCGAGGTGCAGACGCACCCGTGGGGTGTCGATGTGTCCGTC
GTGGAGATTAAGGACGTGGAGATTCCGGAGGCGATGCAGCGGGTCATGGCCCGTGAGGCGGAGGCGGAGCGGGAGCGGCG
GGCGAAAGTCATCAACGCACGCGGCGAGATGCAGGCGTCCGGCGAGTTGCGGCAGGCGGCCGACGAACTCTCGAAGAGCC
CGGCCTCCCTGCAGTTGCGGTATTTGCAGACGCTTCTTGAGCTGGGAGCCGATCAGAACTCGACGGTCGTGTTCCCATTG
CCCATGGATATCCTCGCCCCCTTCCTTCGCAAAGATCACGGGAATTGA

Upstream 100 bases:

>100_bases
TCGAGCAGGCGGCTGCGGTCGAGGCCGAGGTGCGGGGCACGTATGACCGGGGCAGGTACTACCGAGGTGCGGACGACGTC
GATGCCGACAGGAGCAGAAC

Downstream 100 bases:

>100_bases
CCGATGGGGGTCTGGACTTCGGGACGATCGGGTCCTACCCGCGTCCGCGTGGTTCCTGTTTGCTTGAGGTATGGAGCAGT
CGGGTATGTAACCGCCTCAT

Product: stomatin/prohibitin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSDLEWTFTTIALVILVIGFLISSFKIIPEYERGVVFRLGKLRGLHGSGLVFIFPGLDKLHRVDQRTVTLTIPPQEIITR
DNVPARVNAVVLFNVTDPMDAVMNVENYAIATSQIAQTTLRSVLGRADLDTLLAHREELNTDLREIIEVQTHPWGVDVSV
VEIKDVEIPEAMQRVMAREAEAERERRAKVINARGEMQASGELRQAADELSKSPASLQLRYLQTLLELGADQNSTVVFPL
PMDILAPFLRKDHGN

Sequences:

>Translated_255_residues
MSDLEWTFTTIALVILVIGFLISSFKIIPEYERGVVFRLGKLRGLHGSGLVFIFPGLDKLHRVDQRTVTLTIPPQEIITR
DNVPARVNAVVLFNVTDPMDAVMNVENYAIATSQIAQTTLRSVLGRADLDTLLAHREELNTDLREIIEVQTHPWGVDVSV
VEIKDVEIPEAMQRVMAREAEAERERRAKVINARGEMQASGELRQAADELSKSPASLQLRYLQTLLELGADQNSTVVFPL
PMDILAPFLRKDHGN
>Mature_254_residues
SDLEWTFTTIALVILVIGFLISSFKIIPEYERGVVFRLGKLRGLHGSGLVFIFPGLDKLHRVDQRTVTLTIPPQEIITRD
NVPARVNAVVLFNVTDPMDAVMNVENYAIATSQIAQTTLRSVLGRADLDTLLAHREELNTDLREIIEVQTHPWGVDVSVV
EIKDVEIPEAMQRVMAREAEAERERRAKVINARGEMQASGELRQAADELSKSPASLQLRYLQTLLELGADQNSTVVFPLP
MDILAPFLRKDHGN

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI221316744, Length=245, Percent_Identity=48.9795918367347, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI21686995, Length=245, Percent_Identity=48.9795918367347, Blast_Score=208, Evalue=3e-54,
Organism=Homo sapiens, GI38016911, Length=255, Percent_Identity=47.0588235294118, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI7657615, Length=250, Percent_Identity=36.8, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI7305503, Length=174, Percent_Identity=32.7586206896552, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI20149563, Length=156, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI38016907, Length=67, Percent_Identity=52.2388059701493, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1786697, Length=190, Percent_Identity=33.6842105263158, Blast_Score=111, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17570459, Length=251, Percent_Identity=42.2310756972112, Blast_Score=207, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI71987612, Length=251, Percent_Identity=44.6215139442231, Blast_Score=204, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI25153583, Length=251, Percent_Identity=44.6215139442231, Blast_Score=204, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI71987621, Length=251, Percent_Identity=44.6215139442231, Blast_Score=202, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17569493, Length=249, Percent_Identity=42.570281124498, Blast_Score=198, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI193209764, Length=240, Percent_Identity=43.75, Blast_Score=197, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17569497, Length=255, Percent_Identity=40.7843137254902, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17569499, Length=250, Percent_Identity=41.6, Blast_Score=195, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI193210507, Length=253, Percent_Identity=41.501976284585, Blast_Score=191, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17570161, Length=253, Percent_Identity=41.501976284585, Blast_Score=191, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71989948, Length=235, Percent_Identity=41.7021276595745, Blast_Score=180, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI32566490, Length=225, Percent_Identity=45.3333333333333, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71989955, Length=182, Percent_Identity=42.8571428571429, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32564147, Length=178, Percent_Identity=36.5168539325843, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71989963, Length=123, Percent_Identity=41.4634146341463, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17542664, Length=173, Percent_Identity=26.0115606936416, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45556022, Length=254, Percent_Identity=48.8188976377953, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI18860517, Length=252, Percent_Identity=47.2222222222222, Blast_Score=225, Evalue=2e-59,
Organism=Drosophila melanogaster, GI281361633, Length=251, Percent_Identity=39.8406374501992, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI281361631, Length=251, Percent_Identity=39.8406374501992, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI62484448, Length=251, Percent_Identity=46.6135458167331, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI62484274, Length=251, Percent_Identity=46.6135458167331, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24657857, Length=248, Percent_Identity=47.1774193548387, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI281365664, Length=248, Percent_Identity=47.1774193548387, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21356845, Length=243, Percent_Identity=39.0946502057613, Blast_Score=197, Evalue=5e-51,
Organism=Drosophila melanogaster, GI28573263, Length=251, Percent_Identity=38.6454183266932, Blast_Score=180, Evalue=9e-46,
Organism=Drosophila melanogaster, GI281361635, Length=184, Percent_Identity=37.5, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45550506, Length=174, Percent_Identity=32.183908045977, Blast_Score=107, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 28547; Mature: 28416

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLEWTFTTIALVILVIGFLISSFKIIPEYERGVVFRLGKLRGLHGSGLVFIFPGLDKL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCEEEHHHHCCCCCCCEEEEECCHHHH
HRVDQRTVTLTIPPQEIITRDNVPARVNAVVLFNVTDPMDAVMNVENYAIATSQIAQTTL
HHCCCCEEEEEECHHHHHCCCCCCCEEEEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHH
RSVLGRADLDTLLAHREELNTDLREIIEVQTHPWGVDVSVVEIKDVEIPEAMQRVMAREA
HHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
EAERERRAKVINARGEMQASGELRQAADELSKSPASLQLRYLQTLLELGADQNSTVVFPL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
PMDILAPFLRKDHGN
CHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDLEWTFTTIALVILVIGFLISSFKIIPEYERGVVFRLGKLRGLHGSGLVFIFPGLDKL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCEEEHHHHCCCCCCCEEEEECCHHHH
HRVDQRTVTLTIPPQEIITRDNVPARVNAVVLFNVTDPMDAVMNVENYAIATSQIAQTTL
HHCCCCEEEEEECHHHHHCCCCCCCEEEEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHH
RSVLGRADLDTLLAHREELNTDLREIIEVQTHPWGVDVSVVEIKDVEIPEAMQRVMAREA
HHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
EAERERRAKVINARGEMQASGELRQAADELSKSPASLQLRYLQTLLELGADQNSTVVFPL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
PMDILAPFLRKDHGN
CHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]