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The map label for this gene is ytfL [C]

Identifier: 50843196

GI number: 50843196

Start: 1893412

End: 1894818

Strand: Reverse

Name: ytfL [C]

Synonym: PPA1736

Alternate gene names: 50843196

Gene position: 1894818-1893412 (Counterclockwise)

Preceding gene: 50843197

Following gene: 50843195

Centisome position: 74.01

GC content: 58.42

Gene sequence:

>1407_bases
GTGGCTGAGGTCTTTGAGAACGCCGCCCTTATTCTCTTGTTCATCCTCGTGGGCGGGGTGTTTTCGGCTGCCGAGATGGC
GCTGGTGAGCCTCCGCGATTCCCAGATCAAGCAGTTGGCGGCGACCCGCGGATCTCGCGGTCGTTCCATTCAAAAGCTGC
AATCAAATCCCAATCGTTTCCTTTCTGCGGTGCAAATCGGCGTCACCTTGTCAGGCTTCCTCGCCTCGGCCTTTGGTGGT
GCGACGCTGGCCAGCGAGCTCGCGCCAGTATTCGAGTCCTGGGGAATGTCGGCGTCAGTGGCTGCAACGGTCGCCCTCGT
CACTATCACGGTCATTATTTCCTACTTTTCGATCGTGTTAGGTGAGCTTGTAGCTAAGCGTTTGGCGATGCAGCGTGCAG
AGGGATTCTCCGTGGCGCTTGGTCCGATGGTAAATGGCATTGCTACCCTGTTCCGGCCCATCATTTGGTTTCTGGGGGTT
TCGACAGACCTTGTCGTTAAGATCCTTGGCGGTGATCCAACTGCGGCTCGCGAAGAGGTGACCGACGAGGAGATTCGTTC
CATGGTCGTCTCCTCGGCGACGTTGGGGGACGAGGAGCGCACCATCCTTGACGAGGTCTTCGCCGTGGGAGAGAAGTCCC
TGCGCGAGGTAATGGTTCCGCGCACCGAGGTCGACTTTCTGCAGGGATCAATGAAGGCTGTCCAGGCGGCTCAGGTGGTT
CGCGACGGGTCCCATTCTCGGTATCCGGTTATCGACGGATCGGCGGATCGGGTGCTTGGATTCGTTCACGTTCGAGATCT
GCTCGAACTCAACCCTCAGATTCGTACCAGTCGGGTATCCCAACTGGTACGTGCCGTCGTCTCCCTACCCGATACCGTCA
AAGCGCTTAAGGCGCTGACCGAGATGCGTCGCACTAATGCTCATTTGGCGATTGTGCTCGACGAATACGGTGGCACGGCT
GGCATCGTCACTTTGGAGGATCTCGTCGAGGAGATAGTTGGCGATATTACCGATGAGTATGACACCGTTGAACCGTCTGA
TCTGGCTCACGTCAGGCAGCGCGATATTGACGGCCTAACCACGCTCGAAGAGTTTTCCGACAAGGTTGGCCTGGTACTGC
CCGAGGGGCCTTACGACACTCTCGCGGGGTATTTCATGGCTCAGACCGGTGAGGTGCCCACTAAGGGTGCCCAGGTCGAC
GTTCACCTCGATCCGGTTGGATACGTGCCCGATGAAAACGACGAGGATGTTGAACCCGATCCCAATATTGAGCTGACGGT
TACCGAGGTTGATGGTCTACGTGCAGCGTGGCTGAGGATTCGTCGCTTAGATGCGCCTGGCGCGTCAACGGTGCCAGCGG
GGACGTCGACAATCCCGCGCCCTGAGCGGGAGGCGGCAAGCGCGTGA

Upstream 100 bases:

>100_bases
CTGAGCTCCTATTCTTGTCTTATGCACAACGATGACCGGGAGGGCGATAGTCACGCCACCTTCGTTATTGCCTCTGTGAA
GAGAGGAATGGTGAAGGCCC

Downstream 100 bases:

>100_bases
GGAGGCGACCCGCATGGCTCGGCGGTCCCGGAAAAGATGCCGACGGAGCGGTCTTGCTGACTGGCCCGGAGGCCGGCGAG
TTGTTGAAAGCAGCTGTCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MAEVFENAALILLFILVGGVFSAAEMALVSLRDSQIKQLAATRGSRGRSIQKLQSNPNRFLSAVQIGVTLSGFLASAFGG
ATLASELAPVFESWGMSASVAATVALVTITVIISYFSIVLGELVAKRLAMQRAEGFSVALGPMVNGIATLFRPIIWFLGV
STDLVVKILGGDPTAAREEVTDEEIRSMVVSSATLGDEERTILDEVFAVGEKSLREVMVPRTEVDFLQGSMKAVQAAQVV
RDGSHSRYPVIDGSADRVLGFVHVRDLLELNPQIRTSRVSQLVRAVVSLPDTVKALKALTEMRRTNAHLAIVLDEYGGTA
GIVTLEDLVEEIVGDITDEYDTVEPSDLAHVRQRDIDGLTTLEEFSDKVGLVLPEGPYDTLAGYFMAQTGEVPTKGAQVD
VHLDPVGYVPDENDEDVEPDPNIELTVTEVDGLRAAWLRIRRLDAPGASTVPAGTSTIPRPEREAASA

Sequences:

>Translated_468_residues
MAEVFENAALILLFILVGGVFSAAEMALVSLRDSQIKQLAATRGSRGRSIQKLQSNPNRFLSAVQIGVTLSGFLASAFGG
ATLASELAPVFESWGMSASVAATVALVTITVIISYFSIVLGELVAKRLAMQRAEGFSVALGPMVNGIATLFRPIIWFLGV
STDLVVKILGGDPTAAREEVTDEEIRSMVVSSATLGDEERTILDEVFAVGEKSLREVMVPRTEVDFLQGSMKAVQAAQVV
RDGSHSRYPVIDGSADRVLGFVHVRDLLELNPQIRTSRVSQLVRAVVSLPDTVKALKALTEMRRTNAHLAIVLDEYGGTA
GIVTLEDLVEEIVGDITDEYDTVEPSDLAHVRQRDIDGLTTLEEFSDKVGLVLPEGPYDTLAGYFMAQTGEVPTKGAQVD
VHLDPVGYVPDENDEDVEPDPNIELTVTEVDGLRAAWLRIRRLDAPGASTVPAGTSTIPRPEREAASA
>Mature_467_residues
AEVFENAALILLFILVGGVFSAAEMALVSLRDSQIKQLAATRGSRGRSIQKLQSNPNRFLSAVQIGVTLSGFLASAFGGA
TLASELAPVFESWGMSASVAATVALVTITVIISYFSIVLGELVAKRLAMQRAEGFSVALGPMVNGIATLFRPIIWFLGVS
TDLVVKILGGDPTAAREEVTDEEIRSMVVSSATLGDEERTILDEVFAVGEKSLREVMVPRTEVDFLQGSMKAVQAAQVVR
DGSHSRYPVIDGSADRVLGFVHVRDLLELNPQIRTSRVSQLVRAVVSLPDTVKALKALTEMRRTNAHLAIVLDEYGGTAG
IVTLEDLVEEIVGDITDEYDTVEPSDLAHVRQRDIDGLTTLEEFSDKVGLVLPEGPYDTLAGYFMAQTGEVPTKGAQVDV
HLDPVGYVPDENDEDVEPDPNIELTVTEVDGLRAAWLRIRRLDAPGASTVPAGTSTIPRPEREAASA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=392, Percent_Identity=28.3163265306122, Blast_Score=210, Evalue=2e-54,
Organism=Escherichia coli, GI1790664, Length=455, Percent_Identity=22.6373626373626, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI145693175, Length=391, Percent_Identity=23.2736572890026, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI87082033, Length=252, Percent_Identity=30.5555555555556, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786879, Length=213, Percent_Identity=29.5774647887324, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788119, Length=253, Percent_Identity=24.1106719367589, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50257; Mature: 50126

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVFENAALILLFILVGGVFSAAEMALVSLRDSQIKQLAATRGSRGRSIQKLQSNPNRF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHH
LSAVQIGVTLSGFLASAFGGATLASELAPVFESWGMSASVAATVALVTITVIISYFSIVL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GELVAKRLAMQRAEGFSVALGPMVNGIATLFRPIIWFLGVSTDLVVKILGGDPTAAREEV
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCHHHHHC
TDEEIRSMVVSSATLGDEERTILDEVFAVGEKSLREVMVPRTEVDFLQGSMKAVQAAQVV
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RDGSHSRYPVIDGSADRVLGFVHVRDLLELNPQIRTSRVSQLVRAVVSLPDTVKALKALT
HCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
EMRRTNAHLAIVLDEYGGTAGIVTLEDLVEEIVGDITDEYDTVEPSDLAHVRQRDIDGLT
HHHHCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHH
TLEEFSDKVGLVLPEGPYDTLAGYFMAQTGEVPTKGAQVDVHLDPVGYVPDENDEDVEPD
HHHHHCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
PNIELTVTEVDGLRAAWLRIRRLDAPGASTVPAGTSTIPRPEREAASA
CCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
AEVFENAALILLFILVGGVFSAAEMALVSLRDSQIKQLAATRGSRGRSIQKLQSNPNRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHH
LSAVQIGVTLSGFLASAFGGATLASELAPVFESWGMSASVAATVALVTITVIISYFSIVL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GELVAKRLAMQRAEGFSVALGPMVNGIATLFRPIIWFLGVSTDLVVKILGGDPTAAREEV
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCHHHHHC
TDEEIRSMVVSSATLGDEERTILDEVFAVGEKSLREVMVPRTEVDFLQGSMKAVQAAQVV
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RDGSHSRYPVIDGSADRVLGFVHVRDLLELNPQIRTSRVSQLVRAVVSLPDTVKALKALT
HCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
EMRRTNAHLAIVLDEYGGTAGIVTLEDLVEEIVGDITDEYDTVEPSDLAHVRQRDIDGLT
HHHHCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHH
TLEEFSDKVGLVLPEGPYDTLAGYFMAQTGEVPTKGAQVDVHLDPVGYVPDENDEDVEPD
HHHHHCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
PNIELTVTEVDGLRAAWLRIRRLDAPGASTVPAGTSTIPRPEREAASA
CCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]