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The map label for this gene is ydfG [C]

Identifier: 50843173

GI number: 50843173

Start: 1864261

End: 1864995

Strand: Direct

Name: ydfG [C]

Synonym: PPA1711

Alternate gene names: 50843173

Gene position: 1864261-1864995 (Clockwise)

Preceding gene: 50843171

Following gene: 50843175

Centisome position: 72.82

GC content: 63.27

Gene sequence:

>735_bases
ATGAAAGCGCCCACGACGTCAGAAATTTCACACAACAGCCATGGCGCTAAGAGTGTCCTCGTGACCGGGGCCACCCGCGG
CATCGGGCGGGCCATCGCCGACGAGCTAGGGCGCGACCACCACATCATCGTGGGAGGACGCCACCAAGAAGCCGTCGACA
ACGTGGTATCAGAACTACCCAACGCCTCCCCCTTCGTCGTCGATCTGACCGACGAGGAGGCCACCGCTGCAGCCGTCTCC
CACCTGGACCACCTTGACGTCCTTATTAACAGTGCAGGAGTGAGCGCGGCGTCACCTGGCGATATTGCCTCCCAACCCCG
AGACGAATGGCGCCGCGTGCTAGAAATCAACGTCGTCGCCGTCGCCGACCTCACTCGCCTAGTACTTCCCCTACTGCGCG
CCAGCCACGGCGATGTCATCATGATCAATTCCGGATCAGGATTCCTGCGAACCCCCGCCAGCGGTGGCGTATACGCAGCA
TCAAAGTACGCACTGCGAGCACTCACCCACGCCCTACGCGAAGAAGAACGGGGCGTAGTCCGGGTAACCTCCATTCACCC
CGGCCGCGTCGACACCGACATGCAAGTGGAGCTCCAAGCCCAGGCCGGGCGCCCCTACAACGCCGCCGACCATCTGCGTC
CACAGTCGGTTGCCGTCACCGTGCGCGCAGCTTTGGAAGCCAGCCCGGACGCCATGATCGAAGAACTCTCAGTGCGCCCA
GTCTTCCGCGGCTGA

Upstream 100 bases:

>100_bases
CGCTTGAGGTTGTTGGCAACCCGCAGATACATCGCGCCGGCGTCTACGTCGGCCATGATGTACGCGGTATCGCTCCTGGT
AGGACGAGTACGGTGGCGTT

Downstream 100 bases:

>100_bases
TCCACCCCGCAGCACGACCCGGGCCATCAGAGGGCGCAGGGGGCAAGTTGGCCCCAGCATCATCACATGCCAGGGCCAAC
ATCATGTGAACCTTGTGATG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MKAPTTSEISHNSHGAKSVLVTGATRGIGRAIADELGRDHHIIVGGRHQEAVDNVVSELPNASPFVVDLTDEEATAAAVS
HLDHLDVLINSAGVSAASPGDIASQPRDEWRRVLEINVVAVADLTRLVLPLLRASHGDVIMINSGSGFLRTPASGGVYAA
SKYALRALTHALREEERGVVRVTSIHPGRVDTDMQVELQAQAGRPYNAADHLRPQSVAVTVRAALEASPDAMIEELSVRP
VFRG

Sequences:

>Translated_244_residues
MKAPTTSEISHNSHGAKSVLVTGATRGIGRAIADELGRDHHIIVGGRHQEAVDNVVSELPNASPFVVDLTDEEATAAAVS
HLDHLDVLINSAGVSAASPGDIASQPRDEWRRVLEINVVAVADLTRLVLPLLRASHGDVIMINSGSGFLRTPASGGVYAA
SKYALRALTHALREEERGVVRVTSIHPGRVDTDMQVELQAQAGRPYNAADHLRPQSVAVTVRAALEASPDAMIEELSVRP
VFRG
>Mature_244_residues
MKAPTTSEISHNSHGAKSVLVTGATRGIGRAIADELGRDHHIIVGGRHQEAVDNVVSELPNASPFVVDLTDEEATAAAVS
HLDHLDVLINSAGVSAASPGDIASQPRDEWRRVLEINVVAVADLTRLVLPLLRASHGDVIMINSGSGFLRTPASGGVYAA
SKYALRALTHALREEERGVVRVTSIHPGRVDTDMQVELQAQAGRPYNAADHLRPQSVAVTVRAALEASPDAMIEELSVRP
VFRG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=31.2757201646091, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI20149619, Length=231, Percent_Identity=29.8701298701299, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=226, Percent_Identity=30.5309734513274, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=32.972972972973, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=31.0880829015544, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705855, Length=187, Percent_Identity=29.9465240641711, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7705925, Length=201, Percent_Identity=31.3432835820896, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI59889578, Length=163, Percent_Identity=35.5828220858896, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI32455239, Length=190, Percent_Identity=31.0526315789474, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI5031765, Length=190, Percent_Identity=31.0526315789474, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI150247226, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI32483357, Length=209, Percent_Identity=31.1004784688995, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787820, Length=238, Percent_Identity=31.5126050420168, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786701, Length=233, Percent_Identity=30.9012875536481, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787335, Length=189, Percent_Identity=30.6878306878307, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790717, Length=199, Percent_Identity=31.6582914572864, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87082100, Length=217, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787526, Length=192, Percent_Identity=31.7708333333333, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786812, Length=228, Percent_Identity=28.9473684210526, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787905, Length=190, Percent_Identity=28.4210526315789, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=190, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=193, Percent_Identity=31.0880829015544, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=203, Percent_Identity=30.0492610837438, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17558990, Length=210, Percent_Identity=30.4761904761905, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71997402, Length=185, Percent_Identity=28.1081081081081, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=188, Percent_Identity=30.3191489361702, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323882, Length=258, Percent_Identity=30.2325581395349, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6322226, Length=205, Percent_Identity=30.2439024390244, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322227, Length=251, Percent_Identity=28.6852589641434, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641388, Length=241, Percent_Identity=30.7053941908714, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI116007236, Length=243, Percent_Identity=31.2757201646091, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648693, Length=249, Percent_Identity=30.9236947791165, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355889, Length=249, Percent_Identity=30.9236947791165, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24584752, Length=186, Percent_Identity=29.0322580645161, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364494, Length=245, Percent_Identity=27.3469387755102, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=249, Percent_Identity=25.3012048192771, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641232, Length=243, Percent_Identity=29.2181069958848, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648944, Length=238, Percent_Identity=30.672268907563, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI116007234, Length=243, Percent_Identity=27.5720164609054, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI23397609, Length=185, Percent_Identity=34.5945945945946, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571526, Length=193, Percent_Identity=30.5699481865285, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24663911, Length=248, Percent_Identity=28.6290322580645, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25910; Mature: 25910

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAPTTSEISHNSHGAKSVLVTGATRGIGRAIADELGRDHHIIVGGRHQEAVDNVVSELP
CCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCC
NASPFVVDLTDEEATAAAVSHLDHLDVLINSAGVSAASPGDIASQPRDEWRRVLEINVVA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHEEEHH
VADLTRLVLPLLRASHGDVIMINSGSGFLRTPASGGVYAASKYALRALTHALREEERGVV
HHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCEE
RVTSIHPGRVDTDMQVELQAQAGRPYNAADHLRPQSVAVTVRAALEASPDAMIEELSVRP
EEEEECCCCCCCCEEEEEEECCCCCCCHHHHCCCCCEEEEEEEHHCCCHHHHHHHHCCCC
VFRG
CCCC
>Mature Secondary Structure
MKAPTTSEISHNSHGAKSVLVTGATRGIGRAIADELGRDHHIIVGGRHQEAVDNVVSELP
CCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCC
NASPFVVDLTDEEATAAAVSHLDHLDVLINSAGVSAASPGDIASQPRDEWRRVLEINVVA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHEEEHH
VADLTRLVLPLLRASHGDVIMINSGSGFLRTPASGGVYAASKYALRALTHALREEERGVV
HHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCEE
RVTSIHPGRVDTDMQVELQAQAGRPYNAADHLRPQSVAVTVRAALEASPDAMIEELSVRP
EEEEECCCCCCCCEEEEEEECCCCCCCHHHHCCCCCEEEEEEEHHCCCHHHHHHHHCCCC
VFRG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]