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The map label for this gene is dinB

Identifier: 50843133

GI number: 50843133

Start: 1824180

End: 1825577

Strand: Reverse

Name: dinB

Synonym: PPA1670

Alternate gene names: 50843133

Gene position: 1825577-1824180 (Counterclockwise)

Preceding gene: 50843134

Following gene: 50843131

Centisome position: 71.3

GC content: 61.02

Gene sequence:

>1398_bases
ATGAGATCGACGGCGTCGATCCTCCACCTGGACATGGACGCCTTCTTCGCCTCGGTGGAGCAACGGGATAAGCCCTCCCT
CGTTGGTAAGGCTGTCATTGTTGGTGGGGTCGGTGGCAGGGGAGTGGTCGCGACGGCCTCTTATGAGGCCCGCAAATTTG
GGGTGCACTCGGCGATGGCCGGGTCTCAGGCGCGTCGATTGGCCCCGAATGCCGCTTTTTTGTCCGGACGATTTGAGTCC
TACCGGGAGTCCTCGAAGGTTGTCATGGCGACGCTGCGGGAGCTCTCGCCGCTTGTTGAGCCGCTGAGTCTTGACGAAGC
CTTCGTTGATCTAGAAGCCGGTGACGTCGACGTCGAGAACCTTGACGCTTTGCAGCAAGTTGCCGTTGAATTGCGTGCCC
GGGTAGCAGAGCGCACCGAGGGATTGAGTTGCTCGGTGGGTATCGGGTCGAGCAAGTTCATGGCCAAGGTTGCCTCTGAG
ATGGCCAAGCCGCAACGTGGCCATACTGATCAGATCGCCCTCATCGCTCCCGGTACCGAGGCTGACACCATCGCGCCTTT
GTCTGCTCGAGCTATCCCCGGAGTCGGGCCGGTTACGGCGGAACGGTTGGAGAAATTGGGGCTTCGCACTATCGCTGACG
TCCGGGCTGCGCGGGAGTCCGAGTTGGTCCATGAGTTGGGCCATGCTTCCGGGGCGAGCCTCGTCGCCTTGTCACGGGCA
CGGGATGACCGACCGGTAGTGGCTAGCCGAATCGCTAAGTCGATCTCAGTGGAGGATACCTTCGAGCATGACCTCACTCA
TCGCGAGGAGTGCCGTCAGATCGTGGAGCGTCATGCGGGTTTGGTGTGTGGCCGGTTGAAGAAGTCTGGGCAGTTCGCTC
GCACTGTCACTCTTAAGGCGAAGATGGCCGACTTCACCGTCTGGTCGCGGTCGGTGACTCTGACTGGAGCCACCGACTCG
CCTGAGAGGATCTCCCAGCTGGCGGTGCGGATGCTGGATTCCCTTGATCTGCGCGAGGGAGTGCGACTGCTGGGCGTCGG
GGTATCGAATTTCGCCACGTCGGCCCAGGAGGAACTTTTCGTCGTTGATGATGAGGGGAGGCTGCTCGACGAACCCGAGG
TGACCGAGGAGATCACCCCCATCCAGCCGGGACCCTTTGGTCGACGTCGATCTTTTGACGGGCGAAATTGGCCTCCTGGG
GTTGACCTCATTCACGATGAATATGGGCGTGGCTGGGTGTGGGGGTCGGGTCACGGCATTGTCACGTGTCGATTTGAGTA
CCGGGGAAGTGAGATCGGAAGGGTAAAGTCGGTTCCTCAGGACGATGAGGCGCTTCACCCGGCTCATCCTCTTCCGTTGG
CATGGCAACCGCCACAGGAGGACGTCCCCTCCGAGTGA

Upstream 100 bases:

>100_bases
ATGGTGCGGCGCGTTTCCCCGCCATTGACCCTGAGGTGTGGGTGGAGGTTCGTCGTGAGTCTCGTGACGGCTTCGATTTC
GTCGGGTACCGACGCCGGTC

Downstream 100 bases:

>100_bases
CGTGCGCCTCGGACCATGAGGCTGACCCGTCGGGGCGCATTGTGGCCCCGATCAGAACATGGGGATATACGCCACCGATC
CACCTAGTGCCATCAGGGCG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MRSTASILHLDMDAFFASVEQRDKPSLVGKAVIVGGVGGRGVVATASYEARKFGVHSAMAGSQARRLAPNAAFLSGRFES
YRESSKVVMATLRELSPLVEPLSLDEAFVDLEAGDVDVENLDALQQVAVELRARVAERTEGLSCSVGIGSSKFMAKVASE
MAKPQRGHTDQIALIAPGTEADTIAPLSARAIPGVGPVTAERLEKLGLRTIADVRAARESELVHELGHASGASLVALSRA
RDDRPVVASRIAKSISVEDTFEHDLTHREECRQIVERHAGLVCGRLKKSGQFARTVTLKAKMADFTVWSRSVTLTGATDS
PERISQLAVRMLDSLDLREGVRLLGVGVSNFATSAQEELFVVDDEGRLLDEPEVTEEITPIQPGPFGRRRSFDGRNWPPG
VDLIHDEYGRGWVWGSGHGIVTCRFEYRGSEIGRVKSVPQDDEALHPAHPLPLAWQPPQEDVPSE

Sequences:

>Translated_465_residues
MRSTASILHLDMDAFFASVEQRDKPSLVGKAVIVGGVGGRGVVATASYEARKFGVHSAMAGSQARRLAPNAAFLSGRFES
YRESSKVVMATLRELSPLVEPLSLDEAFVDLEAGDVDVENLDALQQVAVELRARVAERTEGLSCSVGIGSSKFMAKVASE
MAKPQRGHTDQIALIAPGTEADTIAPLSARAIPGVGPVTAERLEKLGLRTIADVRAARESELVHELGHASGASLVALSRA
RDDRPVVASRIAKSISVEDTFEHDLTHREECRQIVERHAGLVCGRLKKSGQFARTVTLKAKMADFTVWSRSVTLTGATDS
PERISQLAVRMLDSLDLREGVRLLGVGVSNFATSAQEELFVVDDEGRLLDEPEVTEEITPIQPGPFGRRRSFDGRNWPPG
VDLIHDEYGRGWVWGSGHGIVTCRFEYRGSEIGRVKSVPQDDEALHPAHPLPLAWQPPQEDVPSE
>Mature_465_residues
MRSTASILHLDMDAFFASVEQRDKPSLVGKAVIVGGVGGRGVVATASYEARKFGVHSAMAGSQARRLAPNAAFLSGRFES
YRESSKVVMATLRELSPLVEPLSLDEAFVDLEAGDVDVENLDALQQVAVELRARVAERTEGLSCSVGIGSSKFMAKVASE
MAKPQRGHTDQIALIAPGTEADTIAPLSARAIPGVGPVTAERLEKLGLRTIADVRAARESELVHELGHASGASLVALSRA
RDDRPVVASRIAKSISVEDTFEHDLTHREECRQIVERHAGLVCGRLKKSGQFARTVTLKAKMADFTVWSRSVTLTGATDS
PERISQLAVRMLDSLDLREGVRLLGVGVSNFATSAQEELFVVDDEGRLLDEPEVTEEITPIQPGPFGRRRSFDGRNWPPG
VDLIHDEYGRGWVWGSGHGIVTCRFEYRGSEIGRVKSVPQDDEALHPAHPLPLAWQPPQEDVPSE

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI84043967, Length=418, Percent_Identity=26.3157894736842, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI7706681, Length=419, Percent_Identity=26.2529832935561, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI154350220, Length=329, Percent_Identity=31.0030395136778, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=40.7407407407407, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1786425, Length=273, Percent_Identity=38.4615384615385, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1787432, Length=458, Percent_Identity=26.2008733624454, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=416, Percent_Identity=27.8846153846154, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI193205702, Length=367, Percent_Identity=25.8855585831063, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17537959, Length=304, Percent_Identity=25.3289473684211, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534089, Length=330, Percent_Identity=25.4545454545455, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324921, Length=215, Percent_Identity=28.8372093023256, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19923006, Length=342, Percent_Identity=28.6549707602339, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21355641, Length=286, Percent_Identity=26.2237762237762, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644984, Length=286, Percent_Identity=26.2237762237762, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_PROAC (Q6A763)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056360.1
- HSSP:   Q9UHC5
- ProteinModelPortal:   Q6A763
- SMR:   Q6A763
- GeneID:   2930897
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1670
- NMPDR:   fig|267747.1.peg.1637
- HOGENOM:   HBG734504
- OMA:   MPMAQAR
- ProtClustDB:   PRK03348
- BioCyc:   PACN267747:PPA1670-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 50390; Mature: 50390

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTASILHLDMDAFFASVEQRDKPSLVGKAVIVGGVGGRGVVATASYEARKFGVHSAMA
CCCCCCEEEECHHHHHHHHHHCCCCCHHCCEEEEECCCCCCEEEECCCHHHHHCHHHHHH
GSQARRLAPNAAFLSGRFESYRESSKVVMATLRELSPLVEPLSLDEAFVDLEAGDVDVEN
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCHHH
LDALQQVAVELRARVAERTEGLSCSVGIGSSKFMAKVASEMAKPQRGHTDQIALIAPGTE
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
ADTIAPLSARAIPGVGPVTAERLEKLGLRTIADVRAARESELVHELGHASGASLVALSRA
CCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHC
RDDRPVVASRIAKSISVEDTFEHDLTHREECRQIVERHAGLVCGRLKKSGQFARTVTLKA
CCCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCHHHHHHHCCCCEEEEEEEEE
KMADFTVWSRSVTLTGATDSPERISQLAVRMLDSLDLREGVRLLGVGVSNFATSAQEELF
EHHHEEEEECEEEEECCCCCHHHHHHHHHHHHHHCCHHCCCEEEECCHHHHHCCCCCCEE
VVDDEGRLLDEPEVTEEITPIQPGPFGRRRSFDGRNWPPGVDLIHDEYGRGWVWGSGHGI
EECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEECCCEE
VTCRFEYRGSEIGRVKSVPQDDEALHPAHPLPLAWQPPQEDVPSE
EEEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRSTASILHLDMDAFFASVEQRDKPSLVGKAVIVGGVGGRGVVATASYEARKFGVHSAMA
CCCCCCEEEECHHHHHHHHHHCCCCCHHCCEEEEECCCCCCEEEECCCHHHHHCHHHHHH
GSQARRLAPNAAFLSGRFESYRESSKVVMATLRELSPLVEPLSLDEAFVDLEAGDVDVEN
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCHHH
LDALQQVAVELRARVAERTEGLSCSVGIGSSKFMAKVASEMAKPQRGHTDQIALIAPGTE
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
ADTIAPLSARAIPGVGPVTAERLEKLGLRTIADVRAARESELVHELGHASGASLVALSRA
CCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHC
RDDRPVVASRIAKSISVEDTFEHDLTHREECRQIVERHAGLVCGRLKKSGQFARTVTLKA
CCCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCHHHHHHHCCCCEEEEEEEEE
KMADFTVWSRSVTLTGATDSPERISQLAVRMLDSLDLREGVRLLGVGVSNFATSAQEELF
EHHHEEEEECEEEEECCCCCHHHHHHHHHHHHHHCCHHCCCEEEECCHHHHHCCCCCCEE
VVDDEGRLLDEPEVTEEITPIQPGPFGRRRSFDGRNWPPGVDLIHDEYGRGWVWGSGHGI
EECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEECCCEE
VTCRFEYRGSEIGRVKSVPQDDEALHPAHPLPLAWQPPQEDVPSE
EEEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA