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The map label for this gene is ctaB [H]

Identifier: 50843036

GI number: 50843036

Start: 1681304

End: 1682413

Strand: Reverse

Name: ctaB [H]

Synonym: PPA1561

Alternate gene names: 50843036

Gene position: 1682413-1681304 (Counterclockwise)

Preceding gene: 50843044

Following gene: 50843035

Centisome position: 65.71

GC content: 56.76

Gene sequence:

>1110_bases
ATGAGGACATCGGCGGCCAGAAAGCCTAAAATCGTCAAGACGGCTATTCGTGGCACTTCTCACTTCACGGATGTGCCGTG
CCCAACAGTGGCCGCAATGCCTTTCTCGATTTCGAAGGACACCGTGAGCAACCAGACGACGCACGTGGCGACGGCGCCAG
CCTCTCAGCGTCCCGATCCTGTCGAGACTAAGGTGGAGCAGGAGCAAGGTCGTCCCCGGCTGTCGAGTCGTGACGTAGTG
CATGCCTATGTCGCTCTGACAAAGCCACGCATCATCGAGTTGCTCTTGGTAACAACCCTACCGGTGATGTTCCTGGCCTC
CCATGGTGTGCCGAAGCTCGGTTTAGTGATCGCGACGATGGTTGGTGGACTTTTCGCTGCTGCCAGTGCCAACGTGTTCA
ACTGTGTCATTGACGTCGATATTGACCAAAAAATGCGTCGGACTCGGCGCCGTCCTCTCCCGCGTCATCAAGTGCCGCGT
CGCAGTGCCCTTATTTATGGAATCATACTGTGGATAATTGCCACCATCATCCTGGGATTCGGCGCGAACTGGTTATCAGC
TGCGCTGGCGTTGATTGCCAACCTGTTTTACGTTTTCGTGTATTCTATGCTGCTCAAGCGTCGTACCTGGCAAAACACTA
TTTGGGGCGGTATTGCCGGATGCTTCCCGCCCCTTATCGGTTGGACCGCTGTCACCGGGAGCGTGGGATGGGAGCCGTTG
GTGCTCTTTTTCATCGTTTTCTGGTGGACCCCACCGCATACGTGGGCGCTGTCCTTCCGGTATCGCGAAGACTATGAAGC
CGCTGGCGTGCCCATGCTCCCGGTGGTCAGGGATGCCCCCGAAGTGGCCATCCAGATCCTCATCTACACCGTGATGACGG
TGGCGATCTCCTTGGTGCTGTGGCCGGTGGCCCATATGGGGTGGATCTACGTCGTCGTCGCAGTGGTGTCAGGCGCGGTA
TTCATCGTCGAGGCGGCCCAGTTGCTGCGCCGTGCCAATGCTGGCCTGCGTGATGCCTTACTCAAACCGATGGGTCTATT
CCATTGGTCGAATACTTATCTGTCATTGCTCTTTTTGGCTATCGCGGTTGATCCGCTCATTCATCTGTGA

Upstream 100 bases:

>100_bases
CGGAACCGTTATTCCACCTGCTCAACGGTAGCTGGTCGAACCACTGGTGATTGTGTTCAGCGACGGGCTGACACCGAGAA
CCCCATTCGGAAGGTTGGTG

Downstream 100 bases:

>100_bases
TGACCGTAATGCGGGTGTTATTGGCGGGTTTCCCCGCAGCCCCGTATCGTATCCATTTAGCCTTACCGCAACGGCTAGTA
AGGCACGTCAACACCACATG

Product: membrane protein, putative heme O synthase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MRTSAARKPKIVKTAIRGTSHFTDVPCPTVAAMPFSISKDTVSNQTTHVATAPASQRPDPVETKVEQEQGRPRLSSRDVV
HAYVALTKPRIIELLLVTTLPVMFLASHGVPKLGLVIATMVGGLFAAASANVFNCVIDVDIDQKMRRTRRRPLPRHQVPR
RSALIYGIILWIIATIILGFGANWLSAALALIANLFYVFVYSMLLKRRTWQNTIWGGIAGCFPPLIGWTAVTGSVGWEPL
VLFFIVFWWTPPHTWALSFRYREDYEAAGVPMLPVVRDAPEVAIQILIYTVMTVAISLVLWPVAHMGWIYVVVAVVSGAV
FIVEAAQLLRRANAGLRDALLKPMGLFHWSNTYLSLLFLAIAVDPLIHL

Sequences:

>Translated_369_residues
MRTSAARKPKIVKTAIRGTSHFTDVPCPTVAAMPFSISKDTVSNQTTHVATAPASQRPDPVETKVEQEQGRPRLSSRDVV
HAYVALTKPRIIELLLVTTLPVMFLASHGVPKLGLVIATMVGGLFAAASANVFNCVIDVDIDQKMRRTRRRPLPRHQVPR
RSALIYGIILWIIATIILGFGANWLSAALALIANLFYVFVYSMLLKRRTWQNTIWGGIAGCFPPLIGWTAVTGSVGWEPL
VLFFIVFWWTPPHTWALSFRYREDYEAAGVPMLPVVRDAPEVAIQILIYTVMTVAISLVLWPVAHMGWIYVVVAVVSGAV
FIVEAAQLLRRANAGLRDALLKPMGLFHWSNTYLSLLFLAIAVDPLIHL
>Mature_369_residues
MRTSAARKPKIVKTAIRGTSHFTDVPCPTVAAMPFSISKDTVSNQTTHVATAPASQRPDPVETKVEQEQGRPRLSSRDVV
HAYVALTKPRIIELLLVTTLPVMFLASHGVPKLGLVIATMVGGLFAAASANVFNCVIDVDIDQKMRRTRRRPLPRHQVPR
RSALIYGIILWIIATIILGFGANWLSAALALIANLFYVFVYSMLLKRRTWQNTIWGGIAGCFPPLIGWTAVTGSVGWEPL
VLFFIVFWWTPPHTWALSFRYREDYEAAGVPMLPVVRDAPEVAIQILIYTVMTVAISLVLWPVAHMGWIYVVVAVVSGAV
FIVEAAQLLRRANAGLRDALLKPMGLFHWSNTYLSLLFLAIAVDPLIHL

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=237, Percent_Identity=32.4894514767932, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1786631, Length=233, Percent_Identity=37.3390557939914, Blast_Score=137, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71998235, Length=207, Percent_Identity=28.5024154589372, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325085, Length=246, Percent_Identity=28.8617886178862, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19921064, Length=196, Percent_Identity=32.6530612244898, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 40881; Mature: 40881

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSAARKPKIVKTAIRGTSHFTDVPCPTVAAMPFSISKDTVSNQTTHVATAPASQRPDP
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCHHCCCCCCEEEECCCCCCCCC
VETKVEQEQGRPRLSSRDVVHAYVALTKPRIIELLLVTTLPVMFLASHGVPKLGLVIATM
HHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VGGLFAAASANVFNCVIDVDIDQKMRRTRRRPLPRHQVPRRSALIYGIILWIIATIILGF
HHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GANWLSAALALIANLFYVFVYSMLLKRRTWQNTIWGGIAGCFPPLIGWTAVTGSVGWEPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VLFFIVFWWTPPHTWALSFRYREDYEAAGVPMLPVVRDAPEVAIQILIYTVMTVAISLVL
HHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
WPVAHMGWIYVVVAVVSGAVFIVEAAQLLRRANAGLRDALLKPMGLFHWSNTYLSLLFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAVDPLIHL
HHHHHHHCC
>Mature Secondary Structure
MRTSAARKPKIVKTAIRGTSHFTDVPCPTVAAMPFSISKDTVSNQTTHVATAPASQRPDP
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCHHCCCCCCEEEECCCCCCCCC
VETKVEQEQGRPRLSSRDVVHAYVALTKPRIIELLLVTTLPVMFLASHGVPKLGLVIATM
HHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VGGLFAAASANVFNCVIDVDIDQKMRRTRRRPLPRHQVPRRSALIYGIILWIIATIILGF
HHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GANWLSAALALIANLFYVFVYSMLLKRRTWQNTIWGGIAGCFPPLIGWTAVTGSVGWEPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VLFFIVFWWTPPHTWALSFRYREDYEAAGVPMLPVVRDAPEVAIQILIYTVMTVAISLVL
HHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
WPVAHMGWIYVVVAVVSGAVFIVEAAQLLRRANAGLRDALLKPMGLFHWSNTYLSLLFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAVDPLIHL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA