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The map label for this gene is srlA [H]

Identifier: 50842962

GI number: 50842962

Start: 1602266

End: 1602844

Strand: Direct

Name: srlA [H]

Synonym: PPA1484

Alternate gene names: 50842962

Gene position: 1602266-1602844 (Clockwise)

Preceding gene: 50842961

Following gene: 50842963

Centisome position: 62.58

GC content: 59.24

Gene sequence:

>579_bases
ATGCACTACCTGGTGAAGGCCGCTGAATGGTTCGTCGGCCTGTTCCAAGAAGGTGCGAAGACATTCGTGAGCTGGATGGG
AAGCATCGTGCCCCTGGTGCTTATGCTCCTCATCGCCATGAACTCGCTCATCCGCCTCATTGGTGAGGACCGAATCAACC
GCCTCGCCCAAAAAGCCGGAAACAATCCCGTCAGCCGCTATCTTCTGCTCCCCTTCATCGGCTCATTCATGCTGTGCAAC
CCGATGGTGCACTCCCTGGGCCGATTCCTCCCGGAGCGCTACAAGCCGAGCTACTTCGCTTCGGCGGCCCAGTTCTGCCA
CACCAGCAACGGGATCTTCCCACACATCAATCCTGCCGAACTATTTATCTGGCTCGGCATCGCCCAGGGCATCACGAAGG
CTGGACTACCGACCGGACCGCTGGCGATCCGCTACCTGCTCGTTGGCCTCGTCCTCAACTTCGTCGGTGGCTGGGTGACC
GACTTAACTACCAGATACGTGAGCAGGCAGCAGAAGGTCATCCTCCCCGACACCATGGACGGGAAGATCGTCCACGTCGA
CACCCTTGTGGAGGCCTGA

Upstream 100 bases:

>100_bases
TCACCGCCGTCGACTGAACGGCTCCGCTCAACACAATTCTCCCCCGGTGCTTCCGCAGCCGGGGCCATCCCGAACGCCAC
CACACACGAAGGAGTTGACC

Downstream 100 bases:

>100_bases
GATGACCGAGTACCGCTCCGTCACCGTTTCCCATGGCTCCGGCGGCTACGGCGGCCCCCTCACCATCACCCCTACCGAGG
CTAAACACAAGCTCGTCTAC

Product: PTS system enzyme II sorbitol-specific factor

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Gut; PTS system glucitol/sorbitol-specific EIIC component [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MHYLVKAAEWFVGLFQEGAKTFVSWMGSIVPLVLMLLIAMNSLIRLIGEDRINRLAQKAGNNPVSRYLLLPFIGSFMLCN
PMVHSLGRFLPERYKPSYFASAAQFCHTSNGIFPHINPAELFIWLGIAQGITKAGLPTGPLAIRYLLVGLVLNFVGGWVT
DLTTRYVSRQQKVILPDTMDGKIVHVDTLVEA

Sequences:

>Translated_192_residues
MHYLVKAAEWFVGLFQEGAKTFVSWMGSIVPLVLMLLIAMNSLIRLIGEDRINRLAQKAGNNPVSRYLLLPFIGSFMLCN
PMVHSLGRFLPERYKPSYFASAAQFCHTSNGIFPHINPAELFIWLGIAQGITKAGLPTGPLAIRYLLVGLVLNFVGGWVT
DLTTRYVSRQQKVILPDTMDGKIVHVDTLVEA
>Mature_192_residues
MHYLVKAAEWFVGLFQEGAKTFVSWMGSIVPLVLMLLIAMNSLIRLIGEDRINRLAQKAGNNPVSRYLLLPFIGSFMLCN
PMVHSLGRFLPERYKPSYFASAAQFCHTSNGIFPHINPAELFIWLGIAQGITKAGLPTGPLAIRYLLVGLVLNFVGGWVT
DLTTRYVSRQQKVILPDTMDGKIVHVDTLVEA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3730

COG function: function code G; Phosphotransferase system sorbitol-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994904, Length=174, Percent_Identity=57.4712643678161, Blast_Score=221, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004699 [H]

Pfam domain/function: PF03608 EII-GUT [H]

EC number: 2.7.1.69

Molecular weight: Translated: 21376; Mature: 21376

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS51107 PTS_EIIC_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYLVKAAEWFVGLFQEGAKTFVSWMGSIVPLVLMLLIAMNSLIRLIGEDRINRLAQKAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NNPVSRYLLLPFIGSFMLCNPMVHSLGRFLPERYKPSYFASAAQFCHTSNGIFPHINPAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHH
LFIWLGIAQGITKAGLPTGPLAIRYLLVGLVLNFVGGWVTDLTTRYVSRQQKVILPDTMD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
GKIVHVDTLVEA
CCEEEHHHHHCC
>Mature Secondary Structure
MHYLVKAAEWFVGLFQEGAKTFVSWMGSIVPLVLMLLIAMNSLIRLIGEDRINRLAQKAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NNPVSRYLLLPFIGSFMLCNPMVHSLGRFLPERYKPSYFASAAQFCHTSNGIFPHINPAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHH
LFIWLGIAQGITKAGLPTGPLAIRYLLVGLVLNFVGGWVTDLTTRYVSRQQKVILPDTMD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
GKIVHVDTLVEA
CCEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9435786 [H]