Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 50842949

GI number: 50842949

Start: 1588845

End: 1589585

Strand: Reverse

Name: dapB

Synonym: PPA1470

Alternate gene names: 50842949

Gene position: 1589585-1588845 (Counterclockwise)

Preceding gene: 50842950

Following gene: 50842948

Centisome position: 62.09

GC content: 59.65

Gene sequence:

>741_bases
ATGATTAAGGTCGCTGTGTTCGGAGCCAAGGGACGTATGGGAACTGCGGTGTGCCAGGCCGTCGAGGAAGCTGAGGACAC
CGAGCTTGTTGCGGCTGTTGATAGCGGTGGCGACCGTTCCGACGCTTCGGGAGCCGACGTCATCGTCGACTTCACCACTC
CGGACGCCGTTATGGATAACCTGTCATGGGCGATTTCCCATGACATTAACACTGTCGTCGGCACGACTGGGTTTGACGAT
GAGCGGTATCAGGTTCTGCGCGACCAGCTCGCCGACCATCCGAATATCGGCTGCTTGGTGGCCCCGAACTTTTCTATCGG
CGCTGTCCTCATGATGCACTTCGCCGAGCAGGCCGCAAGGTTCTACGAGTCTGCGGAGATCGTCGAGCTGCATCACCCCA
ATAAGGTTGACGCGCCTTCCGGTACTGCCCGCACAACCGCGACCAAGATTGCCGCAGCGCGTCAAGAGGCCGGTTTGGGA
GAGGTCCCGGACGCAACGAAGAGTCAGCTCAACGGAGCCCGTGGAGCTGTCGTTGAGGGGGTTCACGTCCATAGCGTGCG
TCTACGCGGTCTCGTCGCCCACCAGGAGGTGCTATTCGGAGCTGAGGGAGAGACTCTCACGATCCGACACGATTCCATGG
ACCGAGTCTCCTTCATGTCGGGTGTCCTGACGGGGGTTCGCGGAGTCCTGGATCGTCCTGGTCTGACTGTTGGTATTGAA
GGGTTGCTGGGACTTGAATGA

Upstream 100 bases:

>100_bases
TCGTTGCGCATGGATTGAACATGGCCCAGGAACGTCAGCTTTGCTAGGTAGTCTGGTTCGGGCGCCAGGAGAGGTGCCGT
CGTCAGGAAGGAAGGTCCAG

Downstream 100 bases:

>100_bases
GCGTCCTACGTTCTCGATGACGCCAAGCGAGCCGACTCAGGTACTTCCGCCGAGGCCACGGACCGGTTCTGACACGGTGG
TGACGGTCGACCGTGACCGC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MIKVAVFGAKGRMGTAVCQAVEEAEDTELVAAVDSGGDRSDASGADVIVDFTTPDAVMDNLSWAISHDINTVVGTTGFDD
ERYQVLRDQLADHPNIGCLVAPNFSIGAVLMMHFAEQAARFYESAEIVELHHPNKVDAPSGTARTTATKIAAARQEAGLG
EVPDATKSQLNGARGAVVEGVHVHSVRLRGLVAHQEVLFGAEGETLTIRHDSMDRVSFMSGVLTGVRGVLDRPGLTVGIE
GLLGLE

Sequences:

>Translated_246_residues
MIKVAVFGAKGRMGTAVCQAVEEAEDTELVAAVDSGGDRSDASGADVIVDFTTPDAVMDNLSWAISHDINTVVGTTGFDD
ERYQVLRDQLADHPNIGCLVAPNFSIGAVLMMHFAEQAARFYESAEIVELHHPNKVDAPSGTARTTATKIAAARQEAGLG
EVPDATKSQLNGARGAVVEGVHVHSVRLRGLVAHQEVLFGAEGETLTIRHDSMDRVSFMSGVLTGVRGVLDRPGLTVGIE
GLLGLE
>Mature_246_residues
MIKVAVFGAKGRMGTAVCQAVEEAEDTELVAAVDSGGDRSDASGADVIVDFTTPDAVMDNLSWAISHDINTVVGTTGFDD
ERYQVLRDQLADHPNIGCLVAPNFSIGAVLMMHFAEQAARFYESAEIVELHHPNKVDAPSGTARTTATKIAAARQEAGLG
EVPDATKSQLNGARGAVVEGVHVHSVRLRGLVAHQEVLFGAEGETLTIRHDSMDRVSFMSGVLTGVRGVLDRPGLTVGIE
GLLGLE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=266, Percent_Identity=33.0827067669173, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_PROAC (Q6A7P7)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056176.1
- ProteinModelPortal:   Q6A7P7
- SMR:   Q6A7P7
- GeneID:   2931618
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1470
- NMPDR:   fig|267747.1.peg.1453
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BioCyc:   PACN267747:PPA1470-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 25944; Mature: 25944

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVAVFGAKGRMGTAVCQAVEEAEDTELVAAVDSGGDRSDASGADVIVDFTTPDAVMDN
CEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEECCCHHHHHC
LSWAISHDINTVVGTTGFDDERYQVLRDQLADHPNIGCLVAPNFSIGAVLMMHFAEQAAR
CHHEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHH
FYESAEIVELHHPNKVDAPSGTARTTATKIAAARQEAGLGEVPDATKSQLNGARGAVVEG
HHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCEECC
VHVHSVRLRGLVAHQEVLFGAEGETLTIRHDSMDRVSFMSGVLTGVRGVLDRPGLTVGIE
EEEEEEEHHHHHHHHHHEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEC
GLLGLE
CEECCC
>Mature Secondary Structure
MIKVAVFGAKGRMGTAVCQAVEEAEDTELVAAVDSGGDRSDASGADVIVDFTTPDAVMDN
CEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEECCCHHHHHC
LSWAISHDINTVVGTTGFDDERYQVLRDQLADHPNIGCLVAPNFSIGAVLMMHFAEQAAR
CHHEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHH
FYESAEIVELHHPNKVDAPSGTARTTATKIAAARQEAGLGEVPDATKSQLNGARGAVVEG
HHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCEECC
VHVHSVRLRGLVAHQEVLFGAEGETLTIRHDSMDRVSFMSGVLTGVRGVLDRPGLTVGIE
EEEEEEEHHHHHHHHHHEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEC
GLLGLE
CEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA