Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 50842797

GI number: 50842797

Start: 1428928

End: 1430814

Strand: Direct

Name: recD [H]

Synonym: PPA1317

Alternate gene names: 50842797

Gene position: 1428928-1430814 (Clockwise)

Preceding gene: 50842796

Following gene: 50842802

Centisome position: 55.81

GC content: 59.25

Gene sequence:

>1887_bases
ATGACTGACCTCGTCCCGGTAGCAGCAGGAAGTCGGCTCGAGCCCTTCGCCCGAGCCGGAGTCCTCGAGGCCAGCGACAT
CCATTTAGCCAATCTAGTGTGCCGCATCGGTGGCGAGACCAACTGCGATGTCAGCCTCGCCATCGCTTTATCATGCCGTG
AGCTTCGGCGCGGGTCCGTGTTCTGGGACCCACATGAAATCGCAAACGTCGTCCGCCAGCAAATCCTTGATCCGGCAATT
CCAGACATCGAAACCAGCGACCAGGCAGCCCTATTCGCGGAATTGGAATGGCCACCTCCAGGCGAGTGGCTGTCCACGCT
AGAGGCCAGTCCCGTCATTGCTGGCCGTGATGATCCGCTCAACCGGTTGCCGGCTCGGCTTGATGATGGCCTGGTCTACC
TAGAGAAATATTGGCAAGCTGAGCATGATGTCGCCCGCGATCTCGCTACCCTCGCTGCGGATCCGCCAAGCCAAGGCCCA
GTGTCGGCCGACGATGTTGTTTCCAGCATCAGTAATGCCTTAGCAGCATCCGGAATTATGTTGGATCCAGCTCAAGCTGA
TGCTGCCATCGCCGCAATTATGCACCGAGTTAGTGTGCTTGCAGGTGGCCCCGGAACCGGCAAGACAACTACGGTATGCG
CCCTCCTAGCTGCCTTGCAACAGGCTGACCCTCATCTTGGAGCCGTGGCCCTTGCGGCTCCCAGCGGCAAAGCAGCGGCA
CGCTTGCGTGACTCAGTTTCGCAAGTTTCAGAGCGAATGCCCGATGACCTGAAACCGATTGTTGCTGACGCAACTACCGT
CCACTCACTGCTGAAATGGCAGGGGCCGGGAACCTCATTCGGATATGACGAGCAACACAAGCTTCCGTTCGGAGTCGTCG
TCGTTGACGAAGCATCAATGCTTTCTCTGCCTCTGGCCGCTAGCCTCCTCTCTGCAATCGGGCCTCAAACTCGTCTAATT
CTCGTCGGGGACCCAGGGCAGCTTGTCTCGGTGGACGCCGGTAGTGTCCTGGCCGACATCGTTTCGTCGGCTGATGCCCT
CCAAGCGCAGCTTCCTGTCACGATCCTCACCTGTAACCACCGCTCGAGAGGAGATATCGCACGGCTGTCGGAGGCGGTAC
GCGAGGGAGACAAGAGCACTGCGTTGGACGTATTGGCGACAGCTGCTGGCGTGACACATGACTCTCCTTCCCCCGATAGC
ATCGCGACGATCAGTGGTCGTCGCAGTATTACGTGGATCGACGCTGACCCGGCGAGTATCACCATGGCCGACCTTCCGGC
GGTCGCGGAGGTGATCGCACGCACCGGGGCAAGAATGCTTGAGCTTGCTCAGGCTAGTGCCGACGCTGCTGCTCTCAAAC
TCGTCGATGCCCACCGGTTGTTGTGCGCTCACCGAGAGGGGCCATACGGGGTAGACGAGTGGTCTCAGCGCATGGTTACT
GTACTTTCAGATGTGTTGCCTGGTGTTGGCCAAGGCCGGTGGGTTCTCGGCGAAACTGCAATAGTAACGCATAACCTCGC
ACAATTGGGAGTCAATAACGGCGATTGCGGGGTCATCGTTGAAACAAGGCCCGTCCCCACGATAGCTCTACCGGGACCCG
GTGGAGTCCCCAGACGGTTGCCCTGTTCCCTCATCCCATCGCTGCAACCCTTACAGGCGATGACGATTCACAAAGCGCAG
GGCAGCCAATTCACGGACGTAACGGTGGTCCTGCCACCACCCGACTCGCCCCTCCTCTCTCGTGAGTTGCTCTATACCGC
CATCACGCGTGCACGTGAACACCTCACTGTGGTGGGCACAAGGGAGTCTGTGGAGAGGGCGATTGACCGGGCTAATGATC
GACGTTCTGGGATTCAGCGCCGGTGGGAAGAAAGTCGCACTTCCTGA

Upstream 100 bases:

>100_bases
GATCGTCCAGTACCCGACGGTGACATGCCTGACGGAGTTTTTACCTGGCATCCGAGGCCTGAACTCATTGAGGCGATCAG
CGAGCGATTGGGAGGTCTCC

Downstream 100 bases:

>100_bases
TGAGACCGGAGTCTCAAGGTCGATGGGCTATCACCTCAGTGGGGCCGATAAGTCAAACCCGCTCTCTGGCTCCGGAAGTC
GGTGTTCTAACCACGCGTCA

Product: exonuclease V, alpha chain

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MTDLVPVAAGSRLEPFARAGVLEASDIHLANLVCRIGGETNCDVSLAIALSCRELRRGSVFWDPHEIANVVRQQILDPAI
PDIETSDQAALFAELEWPPPGEWLSTLEASPVIAGRDDPLNRLPARLDDGLVYLEKYWQAEHDVARDLATLAADPPSQGP
VSADDVVSSISNALAASGIMLDPAQADAAIAAIMHRVSVLAGGPGTGKTTTVCALLAALQQADPHLGAVALAAPSGKAAA
RLRDSVSQVSERMPDDLKPIVADATTVHSLLKWQGPGTSFGYDEQHKLPFGVVVVDEASMLSLPLAASLLSAIGPQTRLI
LVGDPGQLVSVDAGSVLADIVSSADALQAQLPVTILTCNHRSRGDIARLSEAVREGDKSTALDVLATAAGVTHDSPSPDS
IATISGRRSITWIDADPASITMADLPAVAEVIARTGARMLELAQASADAAALKLVDAHRLLCAHREGPYGVDEWSQRMVT
VLSDVLPGVGQGRWVLGETAIVTHNLAQLGVNNGDCGVIVETRPVPTIALPGPGGVPRRLPCSLIPSLQPLQAMTIHKAQ
GSQFTDVTVVLPPPDSPLLSRELLYTAITRAREHLTVVGTRESVERAIDRANDRRSGIQRRWEESRTS

Sequences:

>Translated_628_residues
MTDLVPVAAGSRLEPFARAGVLEASDIHLANLVCRIGGETNCDVSLAIALSCRELRRGSVFWDPHEIANVVRQQILDPAI
PDIETSDQAALFAELEWPPPGEWLSTLEASPVIAGRDDPLNRLPARLDDGLVYLEKYWQAEHDVARDLATLAADPPSQGP
VSADDVVSSISNALAASGIMLDPAQADAAIAAIMHRVSVLAGGPGTGKTTTVCALLAALQQADPHLGAVALAAPSGKAAA
RLRDSVSQVSERMPDDLKPIVADATTVHSLLKWQGPGTSFGYDEQHKLPFGVVVVDEASMLSLPLAASLLSAIGPQTRLI
LVGDPGQLVSVDAGSVLADIVSSADALQAQLPVTILTCNHRSRGDIARLSEAVREGDKSTALDVLATAAGVTHDSPSPDS
IATISGRRSITWIDADPASITMADLPAVAEVIARTGARMLELAQASADAAALKLVDAHRLLCAHREGPYGVDEWSQRMVT
VLSDVLPGVGQGRWVLGETAIVTHNLAQLGVNNGDCGVIVETRPVPTIALPGPGGVPRRLPCSLIPSLQPLQAMTIHKAQ
GSQFTDVTVVLPPPDSPLLSRELLYTAITRAREHLTVVGTRESVERAIDRANDRRSGIQRRWEESRTS
>Mature_627_residues
TDLVPVAAGSRLEPFARAGVLEASDIHLANLVCRIGGETNCDVSLAIALSCRELRRGSVFWDPHEIANVVRQQILDPAIP
DIETSDQAALFAELEWPPPGEWLSTLEASPVIAGRDDPLNRLPARLDDGLVYLEKYWQAEHDVARDLATLAADPPSQGPV
SADDVVSSISNALAASGIMLDPAQADAAIAAIMHRVSVLAGGPGTGKTTTVCALLAALQQADPHLGAVALAAPSGKAAAR
LRDSVSQVSERMPDDLKPIVADATTVHSLLKWQGPGTSFGYDEQHKLPFGVVVVDEASMLSLPLAASLLSAIGPQTRLIL
VGDPGQLVSVDAGSVLADIVSSADALQAQLPVTILTCNHRSRGDIARLSEAVREGDKSTALDVLATAAGVTHDSPSPDSI
ATISGRRSITWIDADPASITMADLPAVAEVIARTGARMLELAQASADAAALKLVDAHRLLCAHREGPYGVDEWSQRMVTV
LSDVLPGVGQGRWVLGETAIVTHNLAQLGVNNGDCGVIVETRPVPTIALPGPGGVPRRLPCSLIPSLQPLQAMTIHKAQG
SQFTDVTVVLPPPDSPLLSRELLYTAITRAREHLTVVGTRESVERAIDRANDRRSGIQRRWEESRTS

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=557, Percent_Identity=31.4183123877917, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 66212; Mature: 66081

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLVPVAAGSRLEPFARAGVLEASDIHLANLVCRIGGETNCDVSLAIALSCRELRRGSV
CCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEEHHHHHCCCC
FWDPHEIANVVRQQILDPAIPDIETSDQAALFAELEWPPPGEWLSTLEASPVIAGRDDPL
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCEECCCCCCH
NRLPARLDDGLVYLEKYWQAEHDVARDLATLAADPPSQGPVSADDVVSSISNALAASGIM
HHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCE
LDPAQADAAIAAIMHRVSVLAGGPGTGKTTTVCALLAALQQADPHLGAVALAAPSGKAAA
ECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHH
RLRDSVSQVSERMPDDLKPIVADATTVHSLLKWQGPGTSFGYDEQHKLPFGVVVVDEASM
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHH
LSLPLAASLLSAIGPQTRLILVGDPGQLVSVDAGSVLADIVSSADALQAQLPVTILTCNH
HHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHCCCEEEEEECC
RSRGDIARLSEAVREGDKSTALDVLATAAGVTHDSPSPDSIATISGRRSITWIDADPASI
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEEECCCCEE
TMADLPAVAEVIARTGARMLELAQASADAAALKLVDAHRLLCAHREGPYGVDEWSQRMVT
EHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
VLSDVLPGVGQGRWVLGETAIVTHNLAQLGVNNGDCGVIVETRPVPTIALPGPGGVPRRL
HHHHHCCCCCCCCEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCCCCCCC
PCSLIPSLQPLQAMTIHKAQGSQFTDVTVVLPPPDSPLLSRELLYTAITRAREHLTVVGT
CHHHCCCCCCHHHHHEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEEC
RESVERAIDRANDRRSGIQRRWEESRTS
HHHHHHHHHHCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDLVPVAAGSRLEPFARAGVLEASDIHLANLVCRIGGETNCDVSLAIALSCRELRRGSV
CCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEEHHHHHCCCC
FWDPHEIANVVRQQILDPAIPDIETSDQAALFAELEWPPPGEWLSTLEASPVIAGRDDPL
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCEECCCCCCH
NRLPARLDDGLVYLEKYWQAEHDVARDLATLAADPPSQGPVSADDVVSSISNALAASGIM
HHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCE
LDPAQADAAIAAIMHRVSVLAGGPGTGKTTTVCALLAALQQADPHLGAVALAAPSGKAAA
ECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHH
RLRDSVSQVSERMPDDLKPIVADATTVHSLLKWQGPGTSFGYDEQHKLPFGVVVVDEASM
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHH
LSLPLAASLLSAIGPQTRLILVGDPGQLVSVDAGSVLADIVSSADALQAQLPVTILTCNH
HHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHCCCEEEEEECC
RSRGDIARLSEAVREGDKSTALDVLATAAGVTHDSPSPDSIATISGRRSITWIDADPASI
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEEECCCCEE
TMADLPAVAEVIARTGARMLELAQASADAAALKLVDAHRLLCAHREGPYGVDEWSQRMVT
EHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
VLSDVLPGVGQGRWVLGETAIVTHNLAQLGVNNGDCGVIVETRPVPTIALPGPGGVPRRL
HHHHHCCCCCCCCEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCCCCCCC
PCSLIPSLQPLQAMTIHKAQGSQFTDVTVVLPPPDSPLLSRELLYTAITRAREHLTVVGT
CHHHCCCCCCHHHHHEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEEC
RESVERAIDRANDRRSGIQRRWEESRTS
HHHHHHHHHHCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]