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The map label for this gene is aroA [H]

Identifier: 50842747

GI number: 50842747

Start: 1374808

End: 1376097

Strand: Direct

Name: aroA [H]

Synonym: PPA1268

Alternate gene names: 50842747

Gene position: 1374808-1376097 (Clockwise)

Preceding gene: 50842746

Following gene: 50842748

Centisome position: 53.7

GC content: 61.16

Gene sequence:

>1290_bases
TTGCTGACTGACCAGCATCTGTGGAACGCCCCGCGAGCCGAGCACCTTCTCGCGGGGCGTGTCACGGTCCCGGGGTCAAA
GTCCCAGACGAACCGTGCCCTTGTCCTCGCAGCTCTCAGTGACGGGCCTAGCGTTCTTGAGGGCGTTTTGGCATCCAGAG
ATTCCTATCTCATGTCAGCCGGGCTGCAGCTCCTCGGAGCAGACATTCAGCCCATCGGCCCCGGCTCCGTTCAAGTCATG
CCAGGTCTGGCTCATCCGACCGGCCCGATCGAGTGTGGAATGGCCGGTACCGTGATGAGGTTCCTTCCGGTCGTGGCCGC
GCTGGTGCCTGGACAGACCCGATTCGTGGGAGACGAGCAAGCCTCTCGACGCCCCATCGCGCCAGTTCTCAATGGGTTGC
GCCAGCTCGGCGTCGAGGTTGATTCTGACCGACTGCCGTTTTCCCTGAACGCCCCGGACCGCCTGTGCGGCCCAAAGGTC
ACGATCGATTCGGCGACATCCAGCCAGTTCATCTCGGCCTTGTTGCTAGCCTCAGCTCGTTTCCCACAGGGAATTGACCT
TCGTCATGATGGGGCGTCGGTGCCGTCGACCCCTCACATCGCCATGACCTGCGCCATGTTGGCGGACCGAGGTGTCACCG
TAGTCTCAGACGAGCCGTGCCACTGGGTGGTGCGACCTGGACCAATACATGCCCTCGATGACGTCATCGAACCCGACCTC
ACCAATGCCGCGGTATTCCTCGCAGCTGCCTTAATTGTCGGCGGGTCTGTGACAGTGCCTGGTTGGCCGACAGACAGCAC
CCAGCCTGGCGCACAGTTCATGGGGATCGCCGAAAAGATGGGAGCGATCGTATCCCGTGTTGACGGCTCAATGACTATCG
CCGCCCAAGGCTGGCAAGAGTTGCGGCCTCTTGACGTCGACCTCCATGAGGCCAGTGAACTTACACCAGTCGTTGCAGCT
GTGGCCTCTCTTGCTCGGGGCCGCTCGCGTATCCGTGGTGTGGCGCATATTCGCGGCCACGAAACAGACCGCCTTGCCGC
TCTCGAGCACGAACTGGCTAAGTTGGGCGTTGAGGTCCAGCAAACCGACAACGGCCTAGACATCACTGGTCGAGGTGCTG
ACAAGCTGCACGGTGGAAAATTTGGATGTTACGCCGATCATCGAATGGCTCATGCCGGGGCTCTTCTTGGACTTGTCATC
GACGGGGTTGAGCTCGACGACATCACTTGCACGTCGAAGACCATGCCGCAGTTCCCGCAGATGTGGGCCAACCTCGTCGA
GGAGGTTTGA

Upstream 100 bases:

>100_bases
TTGTCGAAATCGGCCCGTAAGAAGCTAGAGAAGGCCCAGAAGAAAGCCGCTAAGACTCAGAAGAAGGCCCAGAAAAAGGC
CAAGAAAGCTCAGAAGAAGA

Downstream 100 bases:

>100_bases
CGTGTCTCCTCGACGTTTAGCCTCCTCTGGGATCGACATGCGTGACTGGTCCTCCTATGACCGTCCCAAGCGCCGCACCA
AGCCGCGAACCAAGCAGCGT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLTDQHLWNAPRAEHLLAGRVTVPGSKSQTNRALVLAALSDGPSVLEGVLASRDSYLMSAGLQLLGADIQPIGPGSVQVM
PGLAHPTGPIECGMAGTVMRFLPVVAALVPGQTRFVGDEQASRRPIAPVLNGLRQLGVEVDSDRLPFSLNAPDRLCGPKV
TIDSATSSQFISALLLASARFPQGIDLRHDGASVPSTPHIAMTCAMLADRGVTVVSDEPCHWVVRPGPIHALDDVIEPDL
TNAAVFLAAALIVGGSVTVPGWPTDSTQPGAQFMGIAEKMGAIVSRVDGSMTIAAQGWQELRPLDVDLHEASELTPVVAA
VASLARGRSRIRGVAHIRGHETDRLAALEHELAKLGVEVQQTDNGLDITGRGADKLHGGKFGCYADHRMAHAGALLGLVI
DGVELDDITCTSKTMPQFPQMWANLVEEV

Sequences:

>Translated_429_residues
MLTDQHLWNAPRAEHLLAGRVTVPGSKSQTNRALVLAALSDGPSVLEGVLASRDSYLMSAGLQLLGADIQPIGPGSVQVM
PGLAHPTGPIECGMAGTVMRFLPVVAALVPGQTRFVGDEQASRRPIAPVLNGLRQLGVEVDSDRLPFSLNAPDRLCGPKV
TIDSATSSQFISALLLASARFPQGIDLRHDGASVPSTPHIAMTCAMLADRGVTVVSDEPCHWVVRPGPIHALDDVIEPDL
TNAAVFLAAALIVGGSVTVPGWPTDSTQPGAQFMGIAEKMGAIVSRVDGSMTIAAQGWQELRPLDVDLHEASELTPVVAA
VASLARGRSRIRGVAHIRGHETDRLAALEHELAKLGVEVQQTDNGLDITGRGADKLHGGKFGCYADHRMAHAGALLGLVI
DGVELDDITCTSKTMPQFPQMWANLVEEV
>Mature_429_residues
MLTDQHLWNAPRAEHLLAGRVTVPGSKSQTNRALVLAALSDGPSVLEGVLASRDSYLMSAGLQLLGADIQPIGPGSVQVM
PGLAHPTGPIECGMAGTVMRFLPVVAALVPGQTRFVGDEQASRRPIAPVLNGLRQLGVEVDSDRLPFSLNAPDRLCGPKV
TIDSATSSQFISALLLASARFPQGIDLRHDGASVPSTPHIAMTCAMLADRGVTVVSDEPCHWVVRPGPIHALDDVIEPDL
TNAAVFLAAALIVGGSVTVPGWPTDSTQPGAQFMGIAEKMGAIVSRVDGSMTIAAQGWQELRPLDVDLHEASELTPVVAA
VASLARGRSRIRGVAHIRGHETDRLAALEHELAKLGVEVQQTDNGLDITGRGADKLHGGKFGCYADHRMAHAGALLGLVI
DGVELDDITCTSKTMPQFPQMWANLVEEV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=427, Percent_Identity=33.0210772833724, Blast_Score=165, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6320332, Length=441, Percent_Identity=29.4784580498866, Blast_Score=149, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45175; Mature: 45175

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00885 EPSP_SYNTHASE_2 ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDQHLWNAPRAEHLLAGRVTVPGSKSQTNRALVLAALSDGPSVLEGVLASRDSYLMSA
CCCCCCCCCCCCHHHHEECEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHH
GLQLLGADIQPIGPGSVQVMPGLAHPTGPIECGMAGTVMRFLPVVAALVPGQTRFVGDEQ
HHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCH
ASRRPIAPVLNGLRQLGVEVDSDRLPFSLNAPDRLCGPKVTIDSATSSQFISALLLASAR
HCCCCHHHHHHHHHHHCCEECCCCCCEECCCCHHHCCCEEEECCCHHHHHHHHHHHHHCC
FPQGIDLRHDGASVPSTPHIAMTCAMLADRGVTVVSDEPCHWVVRPGPIHALDDVIEPDL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCEEEECCCCCHHHHHHHCCCC
TNAAVFLAAALIVGGSVTVPGWPTDSTQPGAQFMGIAEKMGAIVSRVDGSMTIAAQGWQE
HHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHH
LRPLDVDLHEASELTPVVAAVASLARGRSRIRGVAHIRGHETDRLAALEHELAKLGVEVQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEE
QTDNGLDITGRGADKLHGGKFGCYADHRMAHAGALLGLVIDGVELDDITCTSKTMPQFPQ
ECCCCCEEECCCCCCCCCCEECEEHHHHHHHHHHHHHHHCCCCEECCEEECCCCCCHHHH
MWANLVEEV
HHHHHHHCC
>Mature Secondary Structure
MLTDQHLWNAPRAEHLLAGRVTVPGSKSQTNRALVLAALSDGPSVLEGVLASRDSYLMSA
CCCCCCCCCCCCHHHHEECEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHH
GLQLLGADIQPIGPGSVQVMPGLAHPTGPIECGMAGTVMRFLPVVAALVPGQTRFVGDEQ
HHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCH
ASRRPIAPVLNGLRQLGVEVDSDRLPFSLNAPDRLCGPKVTIDSATSSQFISALLLASAR
HCCCCHHHHHHHHHHHCCEECCCCCCEECCCCHHHCCCEEEECCCHHHHHHHHHHHHHCC
FPQGIDLRHDGASVPSTPHIAMTCAMLADRGVTVVSDEPCHWVVRPGPIHALDDVIEPDL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCEEEECCCCCHHHHHHHCCCC
TNAAVFLAAALIVGGSVTVPGWPTDSTQPGAQFMGIAEKMGAIVSRVDGSMTIAAQGWQE
HHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHH
LRPLDVDLHEASELTPVVAAVASLARGRSRIRGVAHIRGHETDRLAALEHELAKLGVEVQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEE
QTDNGLDITGRGADKLHGGKFGCYADHRMAHAGALLGLVIDGVELDDITCTSKTMPQFPQ
ECCCCCEEECCCCCCCCCCEECEEHHHHHHHHHHHHHHHCCCCEECCEEECCCCCCHHHH
MWANLVEEV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA