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The map label for this gene is atpB [H]

Identifier: 50842725

GI number: 50842725

Start: 1351398

End: 1352174

Strand: Reverse

Name: atpB [H]

Synonym: PPA1245

Alternate gene names: 50842725

Gene position: 1352174-1351398 (Counterclockwise)

Preceding gene: 50842726

Following gene: 50842724

Centisome position: 52.81

GC content: 52.64

Gene sequence:

>777_bases
GTGAGCGGGATCGTGTCTCCTTTGGAGTTTCACACTCCAGGGCTCGAGGACTTCAAGTTCGGCGGGACCTTCGGGGTGGC
TTGGATGGACAAGCCGTTCTGGCAAGTGATCATTGCATTCCTTGTTGTCATCGTCTTCTGGGTGTGGATGAGTCGCGGCC
TTAAAGTTGTACCAGGCAAGCGTCAGGTCTTTGGCGAGTATTGTTACAACTTCATCCGTAATTCTCTGGCGCGAGACACC
ATCGGCCACGGATTTGAACCGTGGTTGCCATATCTGGTTGCCCTCTTCAGCTTTATCCTCATCAACAACTGGTTCGGTGA
ACTATTCGTCTTCATGTTCCCAACTTTTTCCCATGTCGGATACGTTTACGGCTTAGCTATAGTGTCCTGGTTCGTCTACG
TCATCGCTGGGTTTAAGACCAAGGGAATTCGCTACCTTAAGGACTCGGTACTGCCGCCCGGCGTGCCCTGGTACCTACGG
TGCCTCATCATCCCGCTGGAGTTCTTGTCAAACTTCGTCACCCGTCCACTAACGCTGTCGTTGCGACTGTTTGCCAACAT
GGTCGCCGGCCACTTGATCATCATGATCTTCGTCGTTGGTGGCGGATTCCTTCTCACTTACCCGTCCAGCATTATTTACA
ACGTTGCTGGCGGTCTCTCCCTGATCCTCAGCTTCGCGCTCTTTGCGCTGGAGTTGTTTGTGGGCTTTTTGCAGGCTTAC
GTATTTACCGTGCTGTCGGCTCAGTATGTAGCATCCTCGATGTCCGAGGAACACTGA

Upstream 100 bases:

>100_bases
TTTTTGTCGTCGGCATGATCGTCGGCTTTGCGGCGAGCGTTTATCTCATTGTTAAGCGCTACGGGGTCGTGCCCAACCAG
AACAACGACCGGGAGGGTCA

Downstream 100 bases:

>100_bases
CGACACACCACCTCTAGGACCTCGTCGTCAAACCGACCGGCGACGAAGGCAACGCCCCCGGACGGGGCACAAAATCCGGA
AGGAAACACCATGGTACCCA

Product: ATP synthase A chain

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSGIVSPLEFHTPGLEDFKFGGTFGVAWMDKPFWQVIIAFLVVIVFWVWMSRGLKVVPGKRQVFGEYCYNFIRNSLARDT
IGHGFEPWLPYLVALFSFILINNWFGELFVFMFPTFSHVGYVYGLAIVSWFVYVIAGFKTKGIRYLKDSVLPPGVPWYLR
CLIIPLEFLSNFVTRPLTLSLRLFANMVAGHLIIMIFVVGGGFLLTYPSSIIYNVAGGLSLILSFALFALELFVGFLQAY
VFTVLSAQYVASSMSEEH

Sequences:

>Translated_258_residues
MSGIVSPLEFHTPGLEDFKFGGTFGVAWMDKPFWQVIIAFLVVIVFWVWMSRGLKVVPGKRQVFGEYCYNFIRNSLARDT
IGHGFEPWLPYLVALFSFILINNWFGELFVFMFPTFSHVGYVYGLAIVSWFVYVIAGFKTKGIRYLKDSVLPPGVPWYLR
CLIIPLEFLSNFVTRPLTLSLRLFANMVAGHLIIMIFVVGGGFLLTYPSSIIYNVAGGLSLILSFALFALELFVGFLQAY
VFTVLSAQYVASSMSEEH
>Mature_257_residues
SGIVSPLEFHTPGLEDFKFGGTFGVAWMDKPFWQVIIAFLVVIVFWVWMSRGLKVVPGKRQVFGEYCYNFIRNSLARDTI
GHGFEPWLPYLVALFSFILINNWFGELFVFMFPTFSHVGYVYGLAIVSWFVYVIAGFKTKGIRYLKDSVLPPGVPWYLRC
LIIPLEFLSNFVTRPLTLSLRLFANMVAGHLIIMIFVVGGGFLLTYPSSIIYNVAGGLSLILSFALFALELFVGFLQAYV
FTVLSAQYVASSMSEEH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226527, Length=218, Percent_Identity=27.9816513761468, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 29219; Mature: 29088

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGIVSPLEFHTPGLEDFKFGGTFGVAWMDKPFWQVIIAFLVVIVFWVWMSRGLKVVPGK
CCCCCCHHHCCCCCCCCCCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCH
RQVFGEYCYNFIRNSLARDTIGHGFEPWLPYLVALFSFILINNWFGELFVFMFPTFSHVG
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVYGLAIVSWFVYVIAGFKTKGIRYLKDSVLPPGVPWYLRCLIIPLEFLSNFVTRPLTLS
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
LRLFANMVAGHLIIMIFVVGGGFLLTYPSSIIYNVAGGLSLILSFALFALELFVGFLQAY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFTVLSAQYVASSMSEEH
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA