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The map label for this gene is atpD

Identifier: 50842719

GI number: 50842719

Start: 1345628

End: 1347082

Strand: Reverse

Name: atpD

Synonym: PPA1239

Alternate gene names: 50842719

Gene position: 1347082-1345628 (Counterclockwise)

Preceding gene: 50842720

Following gene: 50842718

Centisome position: 52.61

GC content: 59.52

Gene sequence:

>1455_bases
ATGACTGCGACAACAATTACCCCCGAGACGAAGGACGAGGTGGTCGGCGTTGGGCGAGTCGTCCGCGTTATCGGCCCCGT
CGTCGACGTCGAGTTTCCGGCCGGTCAGCTGCCGGAGATTCTCAACGCCCTGCACGTCGATGCTGAGGTGATGGGAGAGA
CTCATGCCATCACCCTCGAGGTGGCCTTGCACATTGGCGAGAATGTCGTGCGAGCCATCTCCCTCAAACCGACTGACGGT
ATGCGCCGCGGCACTGAGGTGCGCGACACCGGTGCCCCGATTAGCGTGCCAGTGGGTGACGTCACTAAGGGTCACGTCTG
GAATGTGACAGGTGACGTTCTTAACGCCGATCCCTCCACAATCGAGGTGACTGAGCGTTGGCCGATCCACCGGGATCCCC
CGGCCTTCGATGACCTTGAGCCCGAGACCGAGATGCTGGAGACCGGTATTAAGGTCCTTGACTTGCTGACTCCTTACGTC
AAGGGCGGCAAGATTGGCCTCTTTGGCGGCGCTGGTGTGGGTAAGACGGTGCTCATTCAGGAGATGATTTACCGTATCGC
CCACAACTTCGGCGGTACCTCGGTTTTCGCCGGTGTCGGTGAACGTACCCGTGAGGGTAACGACCTCATCAACGAGATGG
ACGAGGCCGGTGTGCTCAAGGACACCGCTCTGGTATTCGGCCAGATGGACGAGCCCCCGGGCACGCGTTTGCGCATCGCT
TTGACCGGTTTGACGATGGCTGAGTACTTCCGCGATGTTCAGAACCAGGACGTGCTGTTGTTCATCGACAACATCTTCCG
GTTCTCCCAGGCTGGTTCTGAGGTTTCAACCCTGCTAGGTCGTATGCCCTCGGCGGTGGGCTACCAGCCCAACTTGGCCG
ACGAGATGGGCCAATTGCAGGAGCGAATCACCTCGACCCGTGGCCACTCCATCACCTCGATGCAGGCCGTCTACGTCCCC
GCTGACGATTACACCGACCCGGCTCCGGCGACGACCTTCGCCCATCTGGATGCCACCACGGAGCTTTCTCGTGAGATTGC
CTCTCGTGGCCTGTACCCGGCTGTGGACCCACTGACGTCGACCTCTCGTATCCTCGACCCGCTGTACGTAGGCCAGGAGC
ATTACGACACCGCTACTCAGGTCAAACAGATTCTGCAGCGCAACAAGGAGCTTCAGGACATCATCGCTATTCTCGGTGTG
GATGAGCTGAGCGAAGAGGACAAGGTCACTGTGGCGAGGGCCCGCCGCATCCAGCAGTTCCTGTCCCAGAACACGTACAC
TGCCGAGAAATTCACTGGCGTCGCTGGATCGACGGTTCCGATTGCCGACACAGTTGAGGGATTCCAGATGATCTGCCGTG
GCGACGTTGACCACATTCCCGAGCAGGCCTTCTTCAACGTTGGCAGCATGGACATGGTGATGGAGAACTGGGACAAGATG
AAGAAGGAGGGCTGA

Upstream 100 bases:

>100_bases
ACCAGGCTCGTCAGGCCGCCATTACCCAGGAAATCACCGAGATCGTGGGTGGCGCCGCTGCCCTTGCAGAGTCTGCCCCA
CAGGAGTGAGAGAGAACACC

Downstream 100 bases:

>100_bases
GTCCTATGGACCACCCGCCGCTTCAAGTCAAAGTCGTCAGCGCCGATCGTGAGGTGTGGAAGGGGGAGTCGGTCAATATC
ATTGTTCGGACTACCGAGGG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MTATTITPETKDEVVGVGRVVRVIGPVVDVEFPAGQLPEILNALHVDAEVMGETHAITLEVALHIGENVVRAISLKPTDG
MRRGTEVRDTGAPISVPVGDVTKGHVWNVTGDVLNADPSTIEVTERWPIHRDPPAFDDLEPETEMLETGIKVLDLLTPYV
KGGKIGLFGGAGVGKTVLIQEMIYRIAHNFGGTSVFAGVGERTREGNDLINEMDEAGVLKDTALVFGQMDEPPGTRLRIA
LTGLTMAEYFRDVQNQDVLLFIDNIFRFSQAGSEVSTLLGRMPSAVGYQPNLADEMGQLQERITSTRGHSITSMQAVYVP
ADDYTDPAPATTFAHLDATTELSREIASRGLYPAVDPLTSTSRILDPLYVGQEHYDTATQVKQILQRNKELQDIIAILGV
DELSEEDKVTVARARRIQQFLSQNTYTAEKFTGVAGSTVPIADTVEGFQMICRGDVDHIPEQAFFNVGSMDMVMENWDKM
KKEG

Sequences:

>Translated_484_residues
MTATTITPETKDEVVGVGRVVRVIGPVVDVEFPAGQLPEILNALHVDAEVMGETHAITLEVALHIGENVVRAISLKPTDG
MRRGTEVRDTGAPISVPVGDVTKGHVWNVTGDVLNADPSTIEVTERWPIHRDPPAFDDLEPETEMLETGIKVLDLLTPYV
KGGKIGLFGGAGVGKTVLIQEMIYRIAHNFGGTSVFAGVGERTREGNDLINEMDEAGVLKDTALVFGQMDEPPGTRLRIA
LTGLTMAEYFRDVQNQDVLLFIDNIFRFSQAGSEVSTLLGRMPSAVGYQPNLADEMGQLQERITSTRGHSITSMQAVYVP
ADDYTDPAPATTFAHLDATTELSREIASRGLYPAVDPLTSTSRILDPLYVGQEHYDTATQVKQILQRNKELQDIIAILGV
DELSEEDKVTVARARRIQQFLSQNTYTAEKFTGVAGSTVPIADTVEGFQMICRGDVDHIPEQAFFNVGSMDMVMENWDKM
KKEG
>Mature_483_residues
TATTITPETKDEVVGVGRVVRVIGPVVDVEFPAGQLPEILNALHVDAEVMGETHAITLEVALHIGENVVRAISLKPTDGM
RRGTEVRDTGAPISVPVGDVTKGHVWNVTGDVLNADPSTIEVTERWPIHRDPPAFDDLEPETEMLETGIKVLDLLTPYVK
GGKIGLFGGAGVGKTVLIQEMIYRIAHNFGGTSVFAGVGERTREGNDLINEMDEAGVLKDTALVFGQMDEPPGTRLRIAL
TGLTMAEYFRDVQNQDVLLFIDNIFRFSQAGSEVSTLLGRMPSAVGYQPNLADEMGQLQERITSTRGHSITSMQAVYVPA
DDYTDPAPATTFAHLDATTELSREIASRGLYPAVDPLTSTSRILDPLYVGQEHYDTATQVKQILQRNKELQDIIAILGVD
ELSEEDKVTVARARRIQQFLSQNTYTAEKFTGVAGSTVPIADTVEGFQMICRGDVDHIPEQAFFNVGSMDMVMENWDKMK
KEG

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=472, Percent_Identity=62.9237288135593, Blast_Score=572, Evalue=1e-163,
Organism=Homo sapiens, GI19913424, Length=326, Percent_Identity=30.6748466257669, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI19913426, Length=363, Percent_Identity=22.8650137741047, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI19913428, Length=370, Percent_Identity=22.4324324324324, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI50345984, Length=397, Percent_Identity=23.6775818639798, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4757810, Length=397, Percent_Identity=23.6775818639798, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1790170, Length=463, Percent_Identity=60.6911447084233, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1788251, Length=392, Percent_Identity=30.8673469387755, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1790172, Length=327, Percent_Identity=23.2415902140673, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25144756, Length=472, Percent_Identity=60.3813559322034, Blast_Score=550, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI17565854, Length=353, Percent_Identity=30.5949008498584, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17510931, Length=360, Percent_Identity=23.3333333333333, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17570191, Length=429, Percent_Identity=23.0769230769231, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71988080, Length=400, Percent_Identity=24.25, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71988063, Length=400, Percent_Identity=24.25, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71988074, Length=337, Percent_Identity=23.7388724035608, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322581, Length=462, Percent_Identity=62.1212121212121, Blast_Score=557, Evalue=1e-159,
Organism=Saccharomyces cerevisiae, GI6319603, Length=363, Percent_Identity=23.1404958677686, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320016, Length=258, Percent_Identity=28.2945736434109, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319370, Length=361, Percent_Identity=23.5457063711911, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24638766, Length=472, Percent_Identity=62.9237288135593, Blast_Score=566, Evalue=1e-161,
Organism=Drosophila melanogaster, GI28574560, Length=464, Percent_Identity=60.3448275862069, Blast_Score=528, Evalue=1e-150,
Organism=Drosophila melanogaster, GI24583992, Length=326, Percent_Identity=30.3680981595092, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI20129479, Length=323, Percent_Identity=30.3405572755418, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24583988, Length=324, Percent_Identity=30.8641975308642, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24583986, Length=324, Percent_Identity=30.8641975308642, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24583984, Length=324, Percent_Identity=30.8641975308642, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281361666, Length=364, Percent_Identity=23.0769230769231, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646341, Length=364, Percent_Identity=23.0769230769231, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17136796, Length=364, Percent_Identity=23.0769230769231, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24638768, Length=94, Percent_Identity=51.063829787234, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24658560, Length=295, Percent_Identity=23.3898305084746, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_PROAC (Q6A8C7)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055946.1
- ProteinModelPortal:   Q6A8C7
- SMR:   Q6A8C7
- GeneID:   2932442
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1239
- NMPDR:   fig|267747.1.peg.1223
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- ProtClustDB:   PRK09280
- BioCyc:   PACN267747:PPA1239-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 52869; Mature: 52737

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATTITPETKDEVVGVGRVVRVIGPVVDVEFPAGQLPEILNALHVDAEVMGETHAITLE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHCCCEEEEEE
VALHIGENVVRAISLKPTDGMRRGTEVRDTGAPISVPVGDVTKGHVWNVTGDVLNADPST
EEEHHCCHHHHEEECCCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCEECCCCCE
IEVTERWPIHRDPPAFDDLEPETEMLETGIKVLDLLTPYVKGGKIGLFGGAGVGKTVLIQ
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
EMIYRIAHNFGGTSVFAGVGERTREGNDLINEMDEAGVLKDTALVFGQMDEPPGTRLRIA
HHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEE
LTGLTMAEYFRDVQNQDVLLFIDNIFRFSQAGSEVSTLLGRMPSAVGYQPNLADEMGQLQ
EEHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCHHHHHHHHCCCHHCCCCCCHHHHHHHHH
ERITSTRGHSITSMQAVYVPADDYTDPAPATTFAHLDATTELSREIASRGLYPAVDPLTS
HHHHHCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCH
TSRILDPLYVGQEHYDTATQVKQILQRNKELQDIIAILGVDELSEEDKVTVARARRIQQF
HHHHHHHHHCCCHHCCHHHHHHHHHHHCHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHH
LSQNTYTAEKFTGVAGSTVPIADTVEGFQMICRGDVDHIPEQAFFNVGSMDMVMENWDKM
HHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHCCHHHHHCCCCHHHHHHHHHHH
KKEG
HCCC
>Mature Secondary Structure 
TATTITPETKDEVVGVGRVVRVIGPVVDVEFPAGQLPEILNALHVDAEVMGETHAITLE
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHCCCEEEEEE
VALHIGENVVRAISLKPTDGMRRGTEVRDTGAPISVPVGDVTKGHVWNVTGDVLNADPST
EEEHHCCHHHHEEECCCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCEECCCCCE
IEVTERWPIHRDPPAFDDLEPETEMLETGIKVLDLLTPYVKGGKIGLFGGAGVGKTVLIQ
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
EMIYRIAHNFGGTSVFAGVGERTREGNDLINEMDEAGVLKDTALVFGQMDEPPGTRLRIA
HHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEE
LTGLTMAEYFRDVQNQDVLLFIDNIFRFSQAGSEVSTLLGRMPSAVGYQPNLADEMGQLQ
EEHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCHHHHHHHHCCCHHCCCCCCHHHHHHHHH
ERITSTRGHSITSMQAVYVPADDYTDPAPATTFAHLDATTELSREIASRGLYPAVDPLTS
HHHHHCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCH
TSRILDPLYVGQEHYDTATQVKQILQRNKELQDIIAILGVDELSEEDKVTVARARRIQQF
HHHHHHHHHCCCHHCCHHHHHHHHHHHCHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHH
LSQNTYTAEKFTGVAGSTVPIADTVEGFQMICRGDVDHIPEQAFFNVGSMDMVMENWDKM
HHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHCCHHHHHCCCCHHHHHHHHHHH
KKEG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA