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The map label for this gene is pdxY [H]

Identifier: 50842705

GI number: 50842705

Start: 1332641

End: 1333519

Strand: Direct

Name: pdxY [H]

Synonym: PPA1225

Alternate gene names: 50842705

Gene position: 1332641-1333519 (Clockwise)

Preceding gene: 50842702

Following gene: 50842707

Centisome position: 52.05

GC content: 62.91

Gene sequence:

>879_bases
GTGAGCGTTACTGTCTTATCGCTGCAGTCCCACGTCGTCCAGGGAACCGTCGGCAACAGCATCGCTGTTCCCGTGATGCG
GGCTATGGGCGTGCGCGCCTGGGGGATGCCTACAGCACTGTTGTCAAACCACAATGGACGCTCCAGCGTCGCAGGTATCC
CTATCGATTCTGAGCAGATCGACGCCATGGTTAACGCCCTTGACTCCAATGGTGAGCTCAAACATGTTGATGCGGTGCTG
TCCGGGTACCTCACCCCGCGCACCGGGCCAGCAGTGCTCCGAACCGTGGAGCGGTGCCGTGCCCTCCACCCCGACACGAT
ATGGGTCTGCGACCCCGTCATGGGGGACATGACCCCAGACGGCGAGCTCAGGGCATACGTCCCTGACGAAACCGTGTCAT
TGATGACGGATGCCGTTCAACACGCCGACGTCGTGGTGCCAAACCTCGCCGAGCTGGGCATCCTGACGGGAACCGAGCCT
CGCACTCTTGACGACATCGTCAGAGCGGCTCGAAGTCTCACCGGACCGCACCTTGTCATCGTCACCTCGGTGCCGTACCA
CGACGACGGTGGCGACGGCATCGCGATGGTCGGGGTGACGGGGGAGGGAGCTGTTTTGACCCACGGCCCTCTCTTCGACC
GTTACTTCAACGGCGCAGGCGACCTCACCAGTGCCGTTCTCACCGCAGGGTTGGTGAAAGGGGAGCCACTGGATGCCACG
CTCGGTAAAGCAGCCGGTGTCGTACATACTGTCCTCGAGCGCACCGTGGCGCATCCTGGTGACGAGTTGGACTGGTGGCC
CGAGGACGCCGCGGCTCAGCCATGGAAGACGGTGATCTTGGCTCCCAACGCCCCAAGCCGGGTCGGGAGATCTTCGTAA

Upstream 100 bases:

>100_bases
AGACGGTGAACGGACTCTGGCAATAGGGATAGTCAGTGGCTCTCACAGCAGTCCATTGTGCTCCGGAGAAGTATCAGATG
AGTGACTACCATGGCCTAGT

Downstream 100 bases:

>100_bases
CCGCGGTTGATCATGTAGACGTCGCGCAGGGTCGTTTCTCCCGAAGCGGCCAGAGCGGCCAATAGCAGACAGACGGCAGG
ACGCAAGGCCGGCGGGCAGA

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSVTVLSLQSHVVQGTVGNSIAVPVMRAMGVRAWGMPTALLSNHNGRSSVAGIPIDSEQIDAMVNALDSNGELKHVDAVL
SGYLTPRTGPAVLRTVERCRALHPDTIWVCDPVMGDMTPDGELRAYVPDETVSLMTDAVQHADVVVPNLAELGILTGTEP
RTLDDIVRAARSLTGPHLVIVTSVPYHDDGGDGIAMVGVTGEGAVLTHGPLFDRYFNGAGDLTSAVLTAGLVKGEPLDAT
LGKAAGVVHTVLERTVAHPGDELDWWPEDAAAQPWKTVILAPNAPSRVGRSS

Sequences:

>Translated_292_residues
MSVTVLSLQSHVVQGTVGNSIAVPVMRAMGVRAWGMPTALLSNHNGRSSVAGIPIDSEQIDAMVNALDSNGELKHVDAVL
SGYLTPRTGPAVLRTVERCRALHPDTIWVCDPVMGDMTPDGELRAYVPDETVSLMTDAVQHADVVVPNLAELGILTGTEP
RTLDDIVRAARSLTGPHLVIVTSVPYHDDGGDGIAMVGVTGEGAVLTHGPLFDRYFNGAGDLTSAVLTAGLVKGEPLDAT
LGKAAGVVHTVLERTVAHPGDELDWWPEDAAAQPWKTVILAPNAPSRVGRSS
>Mature_291_residues
SVTVLSLQSHVVQGTVGNSIAVPVMRAMGVRAWGMPTALLSNHNGRSSVAGIPIDSEQIDAMVNALDSNGELKHVDAVLS
GYLTPRTGPAVLRTVERCRALHPDTIWVCDPVMGDMTPDGELRAYVPDETVSLMTDAVQHADVVVPNLAELGILTGTEPR
TLDDIVRAARSLTGPHLVIVTSVPYHDDGGDGIAMVGVTGEGAVLTHGPLFDRYFNGAGDLTSAVLTAGLVKGEPLDATL
GKAAGVVHTVLERTVAHPGDELDWWPEDAAAQPWKTVILAPNAPSRVGRSS

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=268, Percent_Identity=30.2238805970149, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1788758, Length=266, Percent_Identity=31.5789473684211, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787924, Length=270, Percent_Identity=31.8518518518519, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17507759, Length=183, Percent_Identity=34.4262295081967, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17507757, Length=193, Percent_Identity=32.6424870466321, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324354, Length=268, Percent_Identity=30.5970149253731, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320806, Length=240, Percent_Identity=31.25, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45553007, Length=270, Percent_Identity=28.5185185185185, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 30648; Mature: 30517

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTVLSLQSHVVQGTVGNSIAVPVMRAMGVRAWGMPTALLSNHNGRSSVAGIPIDSEQI
CCEEEEEHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCEECCCCCHHHH
DAMVNALDSNGELKHVDAVLSGYLTPRTGPAVLRTVERCRALHPDTIWVCDPVMGDMTPD
HHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
GELRAYVPDETVSLMTDAVQHADVVVPNLAELGILTGTEPRTLDDIVRAARSLTGPHLVI
CCEEEECCCHHHHHHHHHHHHHCEECCCHHHHCEECCCCCCCHHHHHHHHHHCCCCEEEE
VTSVPYHDDGGDGIAMVGVTGEGAVLTHGPLFDRYFNGAGDLTSAVLTAGLVKGEPLDAT
EEECCCCCCCCCEEEEEEECCCCCEEECCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHH
LGKAAGVVHTVLERTVAHPGDELDWWPEDAAAQPWKTVILAPNAPSRVGRSS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SVTVLSLQSHVVQGTVGNSIAVPVMRAMGVRAWGMPTALLSNHNGRSSVAGIPIDSEQI
CEEEEEHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCEECCCCCHHHH
DAMVNALDSNGELKHVDAVLSGYLTPRTGPAVLRTVERCRALHPDTIWVCDPVMGDMTPD
HHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
GELRAYVPDETVSLMTDAVQHADVVVPNLAELGILTGTEPRTLDDIVRAARSLTGPHLVI
CCEEEECCCHHHHHHHHHHHHHCEECCCHHHHCEECCCCCCCHHHHHHHHHHCCCCEEEE
VTSVPYHDDGGDGIAMVGVTGEGAVLTHGPLFDRYFNGAGDLTSAVLTAGLVKGEPLDAT
EEECCCCCCCCCEEEEEEECCCCCEEECCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHH
LGKAAGVVHTVLERTVAHPGDELDWWPEDAAAQPWKTVILAPNAPSRVGRSS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA