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The map label for this gene is rbsK [H]

Identifier: 50842692

GI number: 50842692

Start: 1319703

End: 1320617

Strand: Reverse

Name: rbsK [H]

Synonym: PPA1211

Alternate gene names: 50842692

Gene position: 1320617-1319703 (Counterclockwise)

Preceding gene: 50842693

Following gene: 50842691

Centisome position: 51.58

GC content: 55.85

Gene sequence:

>915_bases
ATGGATATCGCCGTTGTTGGGTCCAATATGGTGGACCTCATCTCCTACATTCATCGCATGCCATCAGACGGTGAAACCGT
CGAGGCTCCCGAATTCCGAATGGGATGCGGCGGCAAAGGTGCGAATCAGGCAGTAGCTGCGTCACGTCTCGGTGCAGAGG
TCGTGATGGTCACCCGAGTGGGCAACGATGTGTTCGCCGACACCACGTTGGACAACTTTCGCAAAAACGGTATCGATACT
ACCCATGTGTTGCGTACCGATGCGAGCTCCGGGGTGGCACCGATCTTCGTCGATCCAGAATCGCGTAACTCCATCCTCAT
CATCAAGGGAGCTAACGCTCAGCTGAGTCCTGCTGATGTCGAGGGTGCCCGACAAGACATTGCCACGTGCAAACTCATCA
TGCTGCAGCTGGAGATTCCGTTGGAGACGGTCTACGCCACGATTGAGTTAGGGGACGTACTGGGGATCCCAATACTCCTC
AATCCGGCTCCGGTCGCACCAGAACTGGATCTTGAGCGAATCCGCGGAATTGAGTTCTTCATGCCGAACGAGTCCGAGCT
TGAACTCATAACGGGGATGCCAGTAGACACCCTCGATGATATCGGCAAGGCTACTGATGTGCTGCTGGGAGCGGGCATCA
CGAATATCATCGTAACTTTGGGCTCGCGTGGTGCGATGTGGGCCCACGCAGAAGGACGCAAAATCATCAAGGCCCCGGTT
GTTCAAGCCGTGGACACGACAGGTGCTGGCGATGCCTTCATAGGCTGCTTTGCTAAAGAATGGGTAGATCACGGCGACGT
GATAGCTGCGATTCGTGCAGGAAACAGGTATGCGGCTGACTCGGTCACACGCCACGGAACTCAGAGCTCGTATGCCTTGG
CCGATGGAAGTCTCCCGGAGTGGCTGAGATCATAG

Upstream 100 bases:

>100_bases
GGAACCCTCATTCATCTGGATGCTGGTGCGACCCGCACGTTCTCTGTAACTACCGGGCTTCTTGCTCAAGGCGAGGCCTT
TGACCGAAAGGCGCAGTGAC

Downstream 100 bases:

>100_bases
TGGGTCTGGGACATTGGGAACCCGGCCCCACCATCCGACGATCCCTGTAGTACCTAGAACAGGAGCCCGAGGAGCTTGTG
ACGTAGCTTACGAAACTAGG

Product: ribokinase family sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDIAVVGSNMVDLISYIHRMPSDGETVEAPEFRMGCGGKGANQAVAASRLGAEVVMVTRVGNDVFADTTLDNFRKNGIDT
THVLRTDASSGVAPIFVDPESRNSILIIKGANAQLSPADVEGARQDIATCKLIMLQLEIPLETVYATIELGDVLGIPILL
NPAPVAPELDLERIRGIEFFMPNESELELITGMPVDTLDDIGKATDVLLGAGITNIIVTLGSRGAMWAHAEGRKIIKAPV
VQAVDTTGAGDAFIGCFAKEWVDHGDVIAAIRAGNRYAADSVTRHGTQSSYALADGSLPEWLRS

Sequences:

>Translated_304_residues
MDIAVVGSNMVDLISYIHRMPSDGETVEAPEFRMGCGGKGANQAVAASRLGAEVVMVTRVGNDVFADTTLDNFRKNGIDT
THVLRTDASSGVAPIFVDPESRNSILIIKGANAQLSPADVEGARQDIATCKLIMLQLEIPLETVYATIELGDVLGIPILL
NPAPVAPELDLERIRGIEFFMPNESELELITGMPVDTLDDIGKATDVLLGAGITNIIVTLGSRGAMWAHAEGRKIIKAPV
VQAVDTTGAGDAFIGCFAKEWVDHGDVIAAIRAGNRYAADSVTRHGTQSSYALADGSLPEWLRS
>Mature_304_residues
MDIAVVGSNMVDLISYIHRMPSDGETVEAPEFRMGCGGKGANQAVAASRLGAEVVMVTRVGNDVFADTTLDNFRKNGIDT
THVLRTDASSGVAPIFVDPESRNSILIIKGANAQLSPADVEGARQDIATCKLIMLQLEIPLETVYATIELGDVLGIPILL
NPAPVAPELDLERIRGIEFFMPNESELELITGMPVDTLDDIGKATDVLLGAGITNIIVTLGSRGAMWAHAEGRKIIKAPV
VQAVDTTGAGDAFIGCFAKEWVDHGDVIAAIRAGNRYAADSVTRHGTQSSYALADGSLPEWLRS

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=290, Percent_Identity=40, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI1790193, Length=290, Percent_Identity=40.3448275862069, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI87081971, Length=305, Percent_Identity=26.2295081967213, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082343, Length=286, Percent_Identity=27.972027972028, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788491, Length=265, Percent_Identity=19.622641509434, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788493, Length=74, Percent_Identity=39.1891891891892, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=309, Percent_Identity=39.4822006472492, Blast_Score=194, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6319884, Length=329, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI20128807, Length=300, Percent_Identity=36.6666666666667, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24583886, Length=304, Percent_Identity=29.2763157894737, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32267; Mature: 32267

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAVVGSNMVDLISYIHRMPSDGETVEAPEFRMGCGGKGANQAVAASRLGAEVVMVTRV
CCEEEECCCHHHHHHHHHHCCCCCCEECCCCEECCCCCCCCCHHHHHHHCCCEEEEEEEC
GNDVFADTTLDNFRKNGIDTTHVLRTDASSGVAPIFVDPESRNSILIIKGANAQLSPADV
CCCEEECCCHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCH
EGARQDIATCKLIMLQLEIPLETVYATIELGDVLGIPILLNPAPVAPELDLERIRGIEFF
HHHHHHHHHEEEEEEEEECCHHHEEEEEEECCCCCCCEEECCCCCCCCCCHHHHCCEEEE
MPNESELELITGMPVDTLDDIGKATDVLLGAGITNIIVTLGSRGAMWAHAEGRKIIKAPV
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHEEEEECCCCCEEEECCCCEEEHHHH
VQAVDTTGAGDAFIGCFAKEWVDHGDVIAAIRAGNRYAADSVTRHGTQSSYALADGSLPE
HHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCEECHHHHHHCCCCCCEEEECCCCHH
WLRS
HHHC
>Mature Secondary Structure
MDIAVVGSNMVDLISYIHRMPSDGETVEAPEFRMGCGGKGANQAVAASRLGAEVVMVTRV
CCEEEECCCHHHHHHHHHHCCCCCCEECCCCEECCCCCCCCCHHHHHHHCCCEEEEEEEC
GNDVFADTTLDNFRKNGIDTTHVLRTDASSGVAPIFVDPESRNSILIIKGANAQLSPADV
CCCEEECCCHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCH
EGARQDIATCKLIMLQLEIPLETVYATIELGDVLGIPILLNPAPVAPELDLERIRGIEFF
HHHHHHHHHEEEEEEEEECCHHHEEEEEEECCCCCCCEEECCCCCCCCCCHHHHCCEEEE
MPNESELELITGMPVDTLDDIGKATDVLLGAGITNIIVTLGSRGAMWAHAEGRKIIKAPV
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHEEEEECCCCCEEEECCCCEEEHHHH
VQAVDTTGAGDAFIGCFAKEWVDHGDVIAAIRAGNRYAADSVTRHGTQSSYALADGSLPE
HHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCEECHHHHHHCCCCCCEEEECCCCHH
WLRS
HHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]