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The map label for this gene is aroE [H]

Identifier: 50842661

GI number: 50842661

Start: 1288376

End: 1289182

Strand: Direct

Name: aroE [H]

Synonym: PPA1181

Alternate gene names: 50842661

Gene position: 1288376-1289182 (Clockwise)

Preceding gene: 50842660

Following gene: 50842662

Centisome position: 50.32

GC content: 61.59

Gene sequence:

>807_bases
ATGCGCTGTGCGGTGATTGGCCATCCAGTGGCTCACTCCTTGTCCCCGGCAATTCACCGCGCCGCATACCAGGTCCTCGG
CCTGGAGTGGTCCTACCAGGCCATCGACGTCGAGCCTGGTGGTTTGCGTGCTTTTATTGAGGGGCTCGACGGTTCCTGGC
GAGGGCTATCAGTGACGATGCCTCACAAGGCCGATCTCGTCGAGTTGGGGGAGACCGACGCGACGGTTGACATGTTGGGA
GCGGCGAATACCTGGGTTTGTCGTGACGGCACGACCATCGTCCGCAATACCGACGTCACGGGGGCAGAGGCTGCGCTTCG
TGCCAGGGGAGTGACTGATGTCGAGAAGGTTGTCATGCTGGGGGCGGGCGCAACAGCCCGGTCTGTTCTTGCGGCTGCCA
TTGGGATGGGAGCGGGCGAAGCCGTCGTGATGTCGCGCTCGCGCGAACGGTCCACGAAGATCCTTAAACTTGCTGATGGC
CTCGGCATTCGTGTTGCCTGGTTGCCTTTCGAATCGGAGCCTCCGCGGTGCAACCTCATAGTCTCGACGGTTCCAGCCGG
TTCCTTGATAAGGCGTGCTGAAGATCTCGCTGCTCGAGCTAATGCGGTTTTTGACGTCGTCTATGATCCCTGGCCAACCC
CTTTGGCCGTGGCTGGGAAGATCGCTGGTGCAACCGTCATTGACGGCTTGGACCTGCTCGCTGGGCAGGCGGTCGGTCAG
GTGCAACTCATGACTGGCTACCCGGTGCCGATGGACGTTTTGAGGTCCACAGCGCAGAACGGCCTGGCTGAGCACGCCCG
CCTTTGA

Upstream 100 bases:

>100_bases
CTGGCTGAGCACGAGAAAAATGTCAAGAAATTCCAAGCTTGGTGTCAGGACCACAAGGGGAAGTGCTAGGACAATACGTG
CTGATCTAGGAGGACTGGCG

Downstream 100 bases:

>100_bases
AAGACTGAATGTTATGCTGCGTTATCTCACTGCCGGGGAGTCTCATGGCCCTGCTCTCGTCGCGACGATGGAGGGCATTC
CGGCTCACGTCCAGGTCGGG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MRCAVIGHPVAHSLSPAIHRAAYQVLGLEWSYQAIDVEPGGLRAFIEGLDGSWRGLSVTMPHKADLVELGETDATVDMLG
AANTWVCRDGTTIVRNTDVTGAEAALRARGVTDVEKVVMLGAGATARSVLAAAIGMGAGEAVVMSRSRERSTKILKLADG
LGIRVAWLPFESEPPRCNLIVSTVPAGSLIRRAEDLAARANAVFDVVYDPWPTPLAVAGKIAGATVIDGLDLLAGQAVGQ
VQLMTGYPVPMDVLRSTAQNGLAEHARL

Sequences:

>Translated_268_residues
MRCAVIGHPVAHSLSPAIHRAAYQVLGLEWSYQAIDVEPGGLRAFIEGLDGSWRGLSVTMPHKADLVELGETDATVDMLG
AANTWVCRDGTTIVRNTDVTGAEAALRARGVTDVEKVVMLGAGATARSVLAAAIGMGAGEAVVMSRSRERSTKILKLADG
LGIRVAWLPFESEPPRCNLIVSTVPAGSLIRRAEDLAARANAVFDVVYDPWPTPLAVAGKIAGATVIDGLDLLAGQAVGQ
VQLMTGYPVPMDVLRSTAQNGLAEHARL
>Mature_268_residues
MRCAVIGHPVAHSLSPAIHRAAYQVLGLEWSYQAIDVEPGGLRAFIEGLDGSWRGLSVTMPHKADLVELGETDATVDMLG
AANTWVCRDGTTIVRNTDVTGAEAALRARGVTDVEKVVMLGAGATARSVLAAAIGMGAGEAVVMSRSRERSTKILKLADG
LGIRVAWLPFESEPPRCNLIVSTVPAGSLIRRAEDLAARANAVFDVVYDPWPTPLAVAGKIAGATVIDGLDLLAGQAVGQ
VQLMTGYPVPMDVLRSTAQNGLAEHARL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=272, Percent_Identity=27.2058823529412, Blast_Score=81, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6320332, Length=276, Percent_Identity=26.4492753623188, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28125; Mature: 28125

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCAVIGHPVAHSLSPAIHRAAYQVLGLEWSYQAIDVEPGGLRAFIEGLDGSWRGLSVTM
CEEEEECCCHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHEECCCCCCCCEEEEC
PHKADLVELGETDATVDMLGAANTWVCRDGTTIVRNTDVTGAEAALRARGVTDVEKVVML
CCCCCCEECCCCCCEEEECCCCCEEEEECCCEEEEECCCCCHHHHHHHCCCCHHHHHHEE
GAGATARSVLAAAIGMGAGEAVVMSRSRERSTKILKLADGLGIRVAWLPFESEPPRCNLI
CCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHEEEEECCCCEEEEEEECCCCCCCCEEE
VSTVPAGSLIRRAEDLAARANAVFDVVYDPWPTPLAVAGKIAGATVIDGLDLLAGQAVGQ
EEECCCHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCE
VQLMTGYPVPMDVLRSTAQNGLAEHARL
EEEEECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRCAVIGHPVAHSLSPAIHRAAYQVLGLEWSYQAIDVEPGGLRAFIEGLDGSWRGLSVTM
CEEEEECCCHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHEECCCCCCCCEEEEC
PHKADLVELGETDATVDMLGAANTWVCRDGTTIVRNTDVTGAEAALRARGVTDVEKVVML
CCCCCCEECCCCCCEEEECCCCCEEEEECCCEEEEECCCCCHHHHHHHCCCCHHHHHHEE
GAGATARSVLAAAIGMGAGEAVVMSRSRERSTKILKLADGLGIRVAWLPFESEPPRCNLI
CCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHEEEEECCCCEEEEEEECCCCCCCCEEE
VSTVPAGSLIRRAEDLAARANAVFDVVYDPWPTPLAVAGKIAGATVIDGLDLLAGQAVGQ
EEECCCHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCE
VQLMTGYPVPMDVLRSTAQNGLAEHARL
EEEEECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA