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The map label for this gene is 50842582

Identifier: 50842582

GI number: 50842582

Start: 1195744

End: 1196202

Strand: Reverse

Name: 50842582

Synonym: PPA1104

Alternate gene names: NA

Gene position: 1196202-1195744 (Counterclockwise)

Preceding gene: 50842584

Following gene: 50842581

Centisome position: 46.72

GC content: 58.61

Gene sequence:

>459_bases
ATGGAGAACTTCAACAACGATCCTTTTGCGTGTATTGATCACGTCGGTTTTGCCGTCAAGGACATGGACGAGGCCATCAA
GTACCACTGCGACGTGCTGGGCTTCCGGGTGCTCTTCCGTGAGAAGAACGAGGGACATGGCGTCGAGGAGGCCATGCTCG
GTACCGGCAAGCGCGGCGAGGAGTCGACCGTCGTTCAGTTGCTCGCCCCGCTCAGCGAAGACAGCACCATTGGAAAGTAC
ATTTCCAAGAATAAGAATATGATCCAGCAGGTGTGCTACCGCACCTACAACCTGGACAAGACGATCGCCACCCTCAAGGA
GCGTGGCGCCGTCTTCACCGGCGAGCCCTCCATCGGAACCGCTGGCTCCCGTGTCATCTTCCTTCACCCCAAGTACACCG
GCGGTCTCCTCATCGAGATCACCGAGCCCCCGGTCGGCGGCATGCCTTACAAGGACTGA

Upstream 100 bases:

>100_bases
GGCCACAGCGTTCCATCGCCTGCAGCACACCTGTGCATAAGGCTCCCGGAATACCTACCCCGCCTGGTTCGACCCTGGTG
GACAGTGCAACGATTGGGCC

Downstream 100 bases:

>100_bases
CGTCACGTCACTGAGGTTGACCCCGGGACCGGTTTATCTTGGCCCCGGGGTCTGTTTCGTTCCGGTGAGTTGCACAGTTG
TCATTCGGTCTTGATTGGTA

Product: methylmalonyl CoA epimerase

Products: (S)-methylmalonyl-CoA

Alternate protein names: Glyoxalase/Bleomycin Resistance Protein/Dioxygenase; Glyoxalase Family Protein; Lactoylglutathione Lyase; Lactoylglutathione Lyase And Related Lyase; Methylmalonyl CoA Epimerase; LAO/AO Transporter ATPase; Methymalonyl-Coa Mutase C-Terminal Domain Protein; Methylmalonyl-CoA Epimerase/Lactoylglutathione Lyase; LAO/AO Transport System ATPase; Glyoxalase/Dioxygenase/Bleomycin Resistance Family Protein

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MENFNNDPFACIDHVGFAVKDMDEAIKYHCDVLGFRVLFREKNEGHGVEEAMLGTGKRGEESTVVQLLAPLSEDSTIGKY
ISKNKNMIQQVCYRTYNLDKTIATLKERGAVFTGEPSIGTAGSRVIFLHPKYTGGLLIEITEPPVGGMPYKD

Sequences:

>Translated_152_residues
MENFNNDPFACIDHVGFAVKDMDEAIKYHCDVLGFRVLFREKNEGHGVEEAMLGTGKRGEESTVVQLLAPLSEDSTIGKY
ISKNKNMIQQVCYRTYNLDKTIATLKERGAVFTGEPSIGTAGSRVIFLHPKYTGGLLIEITEPPVGGMPYKD
>Mature_152_residues
MENFNNDPFACIDHVGFAVKDMDEAIKYHCDVLGFRVLFREKNEGHGVEEAMLGTGKRGEESTVVQLLAPLSEDSTIGKY
ISKNKNMIQQVCYRTYNLDKTIATLKERGAVFTGEPSIGTAGSRVIFLHPKYTGGLLIEITEPPVGGMPYKD

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI188035928, Length=133, Percent_Identity=32.3308270676692, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.1.99.1

Molecular weight: Translated: 16832; Mature: 16832

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENFNNDPFACIDHVGFAVKDMDEAIKYHCDVLGFRVLFREKNEGHGVEEAMLGTGKRGE
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHCCCCCCC
ESTVVQLLAPLSEDSTIGKYISKNKNMIQQVCYRTYNLDKTIATLKERGAVFTGEPSIGT
HHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCC
AGSRVIFLHPKYTGGLLIEITEPPVGGMPYKD
CCCEEEEECCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MENFNNDPFACIDHVGFAVKDMDEAIKYHCDVLGFRVLFREKNEGHGVEEAMLGTGKRGE
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHCCCCCCC
ESTVVQLLAPLSEDSTIGKYISKNKNMIQQVCYRTYNLDKTIATLKERGAVFTGEPSIGT
HHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCC
AGSRVIFLHPKYTGGLLIEITEPPVGGMPYKD
CCCEEEEECCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-methylmalonyl-CoA

Specific reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA