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The map label for this gene is msrB [H]

Identifier: 50842547

GI number: 50842547

Start: 1160521

End: 1160967

Strand: Reverse

Name: msrB [H]

Synonym: PPA1065

Alternate gene names: 50842547

Gene position: 1160967-1160521 (Counterclockwise)

Preceding gene: 50842548

Following gene: 50842546

Centisome position: 45.35

GC content: 58.61

Gene sequence:

>447_bases
ATGGACCACGAACACACCGCGACATACGACCTACAGCCTCACCTCGTGCTCACCCCTGAACAGTGGCACGAGCGTCTAAG
CGACGAGGAATACTACGTGTTGCGCGAAGCGGGGACCGAGGCTCCCTTTGTCGGCGAATACACCGATACCACCACCGAGG
GCGTGTATCGCTGCCGTGCATGTGGAGCCGAGTTGTTCCGCTCTACCCAGAAGTTTCACTCCAGCTGTGGTTGGCCATCT
TTCTATGCGCCGCTGGCTGAGGACCGGGTGCGGTACCTCAACGATGAGTCTCTTCCTGGTCGCCCACGCACCGAAGTGAG
GTGTGCCCAGTGTGATTCCCACCTCGGCCACGTGTTTGCAGGCGAAGGTTTCGACACCCCCACTGACTTGAGGTATTGCA
TTAACTCCATCTGTTTGGACCTGGTACCAACCGACGAGACCACGTGA

Upstream 100 bases:

>100_bases
ACTTCCCGGTCTCGCCGCAATCCGGTAACTCAGGAATGCCGACAAGTCCCTCGCCGTTTCACTGAACACGGAACACGCGG
CACATGCCATCGGAGGGAAT

Downstream 100 bases:

>100_bases
TGGTACCGCGGTTGCAGACCGAAACCCTCAACCTCAACCGCATAGATCCGCAGCACGCGGCGCGTCGAGAGGGCGTCGCA
GGTGTCAGCCCCCATAGCCT

Product: peptide methionine sulfoxide reductase MsrB

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MDHEHTATYDLQPHLVLTPEQWHERLSDEEYYVLREAGTEAPFVGEYTDTTTEGVYRCRACGAELFRSTQKFHSSCGWPS
FYAPLAEDRVRYLNDESLPGRPRTEVRCAQCDSHLGHVFAGEGFDTPTDLRYCINSICLDLVPTDETT

Sequences:

>Translated_148_residues
MDHEHTATYDLQPHLVLTPEQWHERLSDEEYYVLREAGTEAPFVGEYTDTTTEGVYRCRACGAELFRSTQKFHSSCGWPS
FYAPLAEDRVRYLNDESLPGRPRTEVRCAQCDSHLGHVFAGEGFDTPTDLRYCINSICLDLVPTDETT
>Mature_148_residues
MDHEHTATYDLQPHLVLTPEQWHERLSDEEYYVLREAGTEAPFVGEYTDTTTEGVYRCRACGAELFRSTQKFHSSCGWPS
FYAPLAEDRVRYLNDESLPGRPRTEVRCAQCDSHLGHVFAGEGFDTPTDLRYCINSICLDLVPTDETT

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=133, Percent_Identity=40.6015037593985, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI301336162, Length=133, Percent_Identity=40.6015037593985, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI73089054, Length=133, Percent_Identity=40.6015037593985, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI37620216, Length=133, Percent_Identity=40.6015037593985, Blast_Score=110, Evalue=5e-25,
Organism=Homo sapiens, GI117606353, Length=138, Percent_Identity=43.4782608695652, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788077, Length=122, Percent_Identity=45.9016393442623, Blast_Score=114, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17553450, Length=126, Percent_Identity=45.2380952380952, Blast_Score=108, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI115532676, Length=126, Percent_Identity=45.2380952380952, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319816, Length=125, Percent_Identity=41.6, Blast_Score=103, Evalue=8e-24,
Organism=Drosophila melanogaster, GI45553335, Length=134, Percent_Identity=44.7761194029851, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI21356369, Length=134, Percent_Identity=44.7761194029851, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24645799, Length=143, Percent_Identity=44.7552447552448, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24645801, Length=154, Percent_Identity=42.2077922077922, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24645804, Length=145, Percent_Identity=42.0689655172414, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI221378664, Length=130, Percent_Identity=42.3076923076923, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI221378662, Length=137, Percent_Identity=40.1459854014599, Blast_Score=106, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16913; Mature: 16913

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHEHTATYDLQPHLVLTPEQWHERLSDEEYYVLREAGTEAPFVGEYTDTTTEGVYRCRA
CCCCCCEEECCCCCEEECHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
CGAELFRSTQKFHSSCGWPSFYAPLAEDRVRYLNDESLPGRPRTEVRCAQCDSHLGHVFA
HHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEEE
GEGFDTPTDLRYCINSICLDLVPTDETT
CCCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDHEHTATYDLQPHLVLTPEQWHERLSDEEYYVLREAGTEAPFVGEYTDTTTEGVYRCRA
CCCCCCEEECCCCCEEECHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
CGAELFRSTQKFHSSCGWPSFYAPLAEDRVRYLNDESLPGRPRTEVRCAQCDSHLGHVFA
HHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEEE
GEGFDTPTDLRYCINSICLDLVPTDETT
CCCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA