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The map label for this gene is trkA [H]

Identifier: 50842539

GI number: 50842539

Start: 1148534

End: 1149193

Strand: Reverse

Name: trkA [H]

Synonym: PPA1057

Alternate gene names: 50842539

Gene position: 1149193-1148534 (Counterclockwise)

Preceding gene: 50842540

Following gene: 50842534

Centisome position: 44.89

GC content: 58.33

Gene sequence:

>660_bases
GTGAGAATCGTCATCGTTGGAGCCGGTAATGTCGGCCGATCCATTGCCCGTGAGCTCACCGCTCATGGACACCAGATCCT
GCTTATCGACAAGAACCCGAAAGCTATGAAGCCCGACACCGTTCCCGAGGCGGAATGGCTGTGCGCGGACGCATGTGAGC
TGGCTACCTTGGAAGAGGCCCGCATCGACAACTGTGATATCGCTATTTCAGCCACGGGCGATGACAAGGTCAATCTGGTG
CACTCCCTGCTCGCGAAGACTGAGTTTGGGGTGCCAAGGACAGTTGCCCGTGTCAATCACCCCGGGAACGAGTGGATGTT
CGACCAGGTGTGGGGCGTCGATGTTGCCGTTTCAACCCCTCGGCTAATGGCTGCTTTGGTCGAGGAAGCCATTACCGTCG
GTGAATTGGTGCGCCTGTTTACCTTTCAGAAGGGACGCGCGAACCTTGTGGAGCTCACCCTGCCTGACAATTCGCCCCGA
GTCGGTGATCGTATTCGAGACATCTCGATGCCAGGAGACGCAGTTCTGGTCGCCATTATCCGCGATGGGCAAGGCCGAGC
GCCCGAACGTGAGGCCGCGTTGGAGGCTGGCGATGAGCTGCTCTTTATGATCTCGCCCAATTACGAGCCCGATCTGGTTG
ACCTGCTGGCACCACGCTAA

Upstream 100 bases:

>100_bases
GAGGTCGAGCGCATCACCGAGATCGAGGGCCTATTGGCCAAGCCGCCGGTCAAACGTTGATCGTCACGGACAACGCCGTT
CACCCGAGGCAAGGAGAATC

Downstream 100 bases:

>100_bases
CCATGACAAACCTCACGCCCAGTGGGAGTTGACTAGGCCGTGAGGCGGGCGGAAATCGCAAGGCCCGCCGAAGCTACTTC
TCAGTCGGGAAAAATCGTGT

Product: Trk system potassium uptake protein

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRIVIVGAGNVGRSIARELTAHGHQILLIDKNPKAMKPDTVPEAEWLCADACELATLEEARIDNCDIAISATGDDKVNLV
HSLLAKTEFGVPRTVARVNHPGNEWMFDQVWGVDVAVSTPRLMAALVEEAITVGELVRLFTFQKGRANLVELTLPDNSPR
VGDRIRDISMPGDAVLVAIIRDGQGRAPEREAALEAGDELLFMISPNYEPDLVDLLAPR

Sequences:

>Translated_219_residues
MRIVIVGAGNVGRSIARELTAHGHQILLIDKNPKAMKPDTVPEAEWLCADACELATLEEARIDNCDIAISATGDDKVNLV
HSLLAKTEFGVPRTVARVNHPGNEWMFDQVWGVDVAVSTPRLMAALVEEAITVGELVRLFTFQKGRANLVELTLPDNSPR
VGDRIRDISMPGDAVLVAIIRDGQGRAPEREAALEAGDELLFMISPNYEPDLVDLLAPR
>Mature_219_residues
MRIVIVGAGNVGRSIARELTAHGHQILLIDKNPKAMKPDTVPEAEWLCADACELATLEEARIDNCDIAISATGDDKVNLV
HSLLAKTEFGVPRTVARVNHPGNEWMFDQVWGVDVAVSTPRLMAALVEEAITVGELVRLFTFQKGRANLVELTLPDNSPR
VGDRIRDISMPGDAVLVAIIRDGQGRAPEREAALEAGDELLFMISPNYEPDLVDLLAPR

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=221, Percent_Identity=24.8868778280543, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 23865; Mature: 23865

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVIVGAGNVGRSIARELTAHGHQILLIDKNPKAMKPDTVPEAEWLCADACELATLEEA
CEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RIDNCDIAISATGDDKVNLVHSLLAKTEFGVPRTVARVNHPGNEWMFDQVWGVDVAVSTP
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEHHHCCEEEEECCH
RLMAALVEEAITVGELVRLFTFQKGRANLVELTLPDNSPRVGDRIRDISMPGDAVLVAII
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHEECCCCCCEEEEEEE
RDGQGRAPEREAALEAGDELLFMISPNYEPDLVDLLAPR
ECCCCCCCCHHHHHHCCCEEEEEECCCCCCCHHHHCCCC
>Mature Secondary Structure
MRIVIVGAGNVGRSIARELTAHGHQILLIDKNPKAMKPDTVPEAEWLCADACELATLEEA
CEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RIDNCDIAISATGDDKVNLVHSLLAKTEFGVPRTVARVNHPGNEWMFDQVWGVDVAVSTP
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEHHHCCEEEEECCH
RLMAALVEEAITVGELVRLFTFQKGRANLVELTLPDNSPRVGDRIRDISMPGDAVLVAII
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHEECCCCCCEEEEEEE
RDGQGRAPEREAALEAGDELLFMISPNYEPDLVDLLAPR
ECCCCCCCCHHHHHHCCCEEEEEECCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 9784509 [H]