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The map label for this gene is yxjM [H]

Identifier: 50842409

GI number: 50842409

Start: 1008533

End: 1009882

Strand: Direct

Name: yxjM [H]

Synonym: PPA0925

Alternate gene names: 50842409

Gene position: 1008533-1009882 (Clockwise)

Preceding gene: 50842408

Following gene: 50842410

Centisome position: 39.39

GC content: 62.37

Gene sequence:

>1350_bases
GTGCCACTCGTTACGCTCGGGGGCGTGCGAGAATCGATCGTGTCCTTCATGGCGATGGACGACCTATGGCGTCGCCGAGT
GCCGGAGCATAAGGGCTGGCAGATCTCGGTCGTGTGGTTCCTGCCCGCTGTTGACGTGCTCGTCGGAGCGCTCGTGGCCC
TGGCCGTGGGTGCCGGCGGGCTGTTGCTGGCGGCTCTTCAGGACCACCTTGATACCCTCGGACCAGGTGATGTCATCGTT
GTCATCGTCCTTGCCGTGGCTCTTTCCTTTCGACGGGTGATGCCAATCACCTCGGCTGCCGTCATGACTCTCGTCTGGAT
TAACGGAACCTATGCGACGCCGTACATGGCGACGAACTGGGTGTCGACCTTGGCCTTTTTCTTCTCCTACTACTCCCTCA
TGGTGTGGGTACGGACACGTCGAATCGCGTGGGGATCGATGTTGGCGGTCTTCGTCGTCATCATGGGCTGGGTCGTCATG
ATGATGGCCTTCGGGAGGTCGCTCACCGAGCAGTTCGAGATCATCAATCCCGACAGCAATGGGGAGGGGGTCATCTACCT
CGTCCTCACCTATGTGATCGTCAATGTCACCTTCGTCGTCGGAGCCGCATTGGTGGGGCAGGTGTCCTGGCTGTGGGCAC
GAGACCTAGCCGAGGTTCGCCGTCAGGCCGCTACAATCGAACGACAGCGTACCCAGCTCGCTGAGCAAGCAGTTCTCGAC
GAGAGGTTGCGGATCGCCCGGGAGATGCACGATTCGATGGCCCATCACGTGTCGGTCGTGGGGATCCATGCCGCAGGTGC
TCGTCGAGCCCTTGACGTCGATCCTGATCTGGCTCGGGAGGCCTTGGCAACCGTGGAATCGGAGTCCCGGGAAGCTGTCA
CCGAGATGCGATCCCTGCTGGGATCCTTGCGGGCCGGTGACGAGCCACGTGCCCGCCTCGGCCTGGCTGACCTTGACCGA
CTGTGCGATGAACCTCGGCGCGCGTCGGTGCGGTTGCTGCGAGTGGGAGATGATTCCCTGGTTGGTCCACAGCTGGGTCA
CACCTGTTACCGAATCGTCCAGGAATCCCTCAACAATGTGGAGGCCCACTCTAGCGCCACCGAGGTGACGGTGTCGGTAC
GCTGCAGCGATGACGAGGTCGAGGTGGAGGTCACCGACAACGGCCGCCCGATTCGATCGGCACCCTCGACCGGGGTGGGA
ATCGTCGGGATGTCAGAGCGGGTCGAGGCCCTAGGCGGCACCATTGAGGTGGGTCCACGCAAGGTCGGTGGATGGCGAGT
TCGTGCCGTCATGCCGATGCGTCAGAGCCAGGATGTGAGGGACGAGGACATGAAGGAGGGGGAGGACTGA

Upstream 100 bases:

>100_bases
AGTTCATGGGGCGGTGGAATGCCAACGGCGGGAGGCTGGCCAAGGTTAACTGACAGGGCTGTTCTCCGGAAACTCATCCT
TACGACGGAGGAGACTGACA

Downstream 100 bases:

>100_bases
TGCGCGTCGTGCTGGTCGACGACCAGAAACTAGTTCGTCAAGGGTTTCGCCTCATCCTCGCGGTGGAGCCCGACATCACG
GTTGTTGGGGAGGCCACCAA

Product: putative two-component system sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MPLVTLGGVRESIVSFMAMDDLWRRRVPEHKGWQISVVWFLPAVDVLVGALVALAVGAGGLLLAALQDHLDTLGPGDVIV
VIVLAVALSFRRVMPITSAAVMTLVWINGTYATPYMATNWVSTLAFFFSYYSLMVWVRTRRIAWGSMLAVFVVIMGWVVM
MMAFGRSLTEQFEIINPDSNGEGVIYLVLTYVIVNVTFVVGAALVGQVSWLWARDLAEVRRQAATIERQRTQLAEQAVLD
ERLRIAREMHDSMAHHVSVVGIHAAGARRALDVDPDLAREALATVESESREAVTEMRSLLGSLRAGDEPRARLGLADLDR
LCDEPRRASVRLLRVGDDSLVGPQLGHTCYRIVQESLNNVEAHSSATEVTVSVRCSDDEVEVEVTDNGRPIRSAPSTGVG
IVGMSERVEALGGTIEVGPRKVGGWRVRAVMPMRQSQDVRDEDMKEGED

Sequences:

>Translated_449_residues
MPLVTLGGVRESIVSFMAMDDLWRRRVPEHKGWQISVVWFLPAVDVLVGALVALAVGAGGLLLAALQDHLDTLGPGDVIV
VIVLAVALSFRRVMPITSAAVMTLVWINGTYATPYMATNWVSTLAFFFSYYSLMVWVRTRRIAWGSMLAVFVVIMGWVVM
MMAFGRSLTEQFEIINPDSNGEGVIYLVLTYVIVNVTFVVGAALVGQVSWLWARDLAEVRRQAATIERQRTQLAEQAVLD
ERLRIAREMHDSMAHHVSVVGIHAAGARRALDVDPDLAREALATVESESREAVTEMRSLLGSLRAGDEPRARLGLADLDR
LCDEPRRASVRLLRVGDDSLVGPQLGHTCYRIVQESLNNVEAHSSATEVTVSVRCSDDEVEVEVTDNGRPIRSAPSTGVG
IVGMSERVEALGGTIEVGPRKVGGWRVRAVMPMRQSQDVRDEDMKEGED
>Mature_448_residues
PLVTLGGVRESIVSFMAMDDLWRRRVPEHKGWQISVVWFLPAVDVLVGALVALAVGAGGLLLAALQDHLDTLGPGDVIVV
IVLAVALSFRRVMPITSAAVMTLVWINGTYATPYMATNWVSTLAFFFSYYSLMVWVRTRRIAWGSMLAVFVVIMGWVVMM
MAFGRSLTEQFEIINPDSNGEGVIYLVLTYVIVNVTFVVGAALVGQVSWLWARDLAEVRRQAATIERQRTQLAEQAVLDE
RLRIAREMHDSMAHHVSVVGIHAAGARRALDVDPDLAREALATVESESREAVTEMRSLLGSLRAGDEPRARLGLADLDRL
CDEPRRASVRLLRVGDDSLVGPQLGHTCYRIVQESLNNVEAHSSATEVTVSVRCSDDEVEVEVTDNGRPIRSAPSTGVGI
VGMSERVEALGGTIEVGPRKVGGWRVRAVMPMRQSQDVRDEDMKEGED

Specific function: Probable member of the two-component regulatory system yxjM/yxjL. May activate yxjL by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=220, Percent_Identity=31.3636363636364, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788812, Length=195, Percent_Identity=29.7435897435897, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49332; Mature: 49200

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVTLGGVRESIVSFMAMDDLWRRRVPEHKGWQISVVWFLPAVDVLVGALVALAVGAGG
CCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCH
LLLAALQDHLDTLGPGDVIVVIVLAVALSFRRVMPITSAAVMTLVWINGTYATPYMATNW
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCCCCCHHHHH
VSTLAFFFSYYSLMVWVRTRRIAWGSMLAVFVVIMGWVVMMMAFGRSLTEQFEIINPDSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCEEECCCCC
GEGVIYLVLTYVIVNVTFVVGAALVGQVSWLWARDLAEVRRQAATIERQRTQLAEQAVLD
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLRIAREMHDSMAHHVSVVGIHAAGARRALDVDPDLAREALATVESESREAVTEMRSLL
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLRAGDEPRARLGLADLDRLCDEPRRASVRLLRVGDDSLVGPQLGHTCYRIVQESLNNV
HHHCCCCCCHHHCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
EAHSSATEVTVSVRCSDDEVEVEVTDNGRPIRSAPSTGVGIVGMSERVEALGGTIEVGPR
HHCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEECHHHHHHHCCCEEEECCC
KVGGWRVRAVMPMRQSQDVRDEDMKEGED
CCCCEEEEEECCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
PLVTLGGVRESIVSFMAMDDLWRRRVPEHKGWQISVVWFLPAVDVLVGALVALAVGAGG
CEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCH
LLLAALQDHLDTLGPGDVIVVIVLAVALSFRRVMPITSAAVMTLVWINGTYATPYMATNW
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCCCCCHHHHH
VSTLAFFFSYYSLMVWVRTRRIAWGSMLAVFVVIMGWVVMMMAFGRSLTEQFEIINPDSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCEEECCCCC
GEGVIYLVLTYVIVNVTFVVGAALVGQVSWLWARDLAEVRRQAATIERQRTQLAEQAVLD
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLRIAREMHDSMAHHVSVVGIHAAGARRALDVDPDLAREALATVESESREAVTEMRSLL
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLRAGDEPRARLGLADLDRLCDEPRRASVRLLRVGDDSLVGPQLGHTCYRIVQESLNNV
HHHCCCCCCHHHCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
EAHSSATEVTVSVRCSDDEVEVEVTDNGRPIRSAPSTGVGIVGMSERVEALGGTIEVGPR
HHCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEECHHHHHHHCCCEEEECCC
KVGGWRVRAVMPMRQSQDVRDEDMKEGED
CCCCEEEEEECCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]