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The map label for this gene is spoVD [H]

Identifier: 50842239

GI number: 50842239

Start: 825137

End: 827062

Strand: Direct

Name: spoVD [H]

Synonym: PPA0752

Alternate gene names: 50842239

Gene position: 825137-827062 (Clockwise)

Preceding gene: 50842238

Following gene: 50842240

Centisome position: 32.23

GC content: 59.45

Gene sequence:

>1926_bases
GTGAGTTCCCGGCATCCTACGGGCCCGAACTCACGGCCCGGGTCCGCCAGGCGGCCCGCGTCCAACCGTGGTCCCGGGCG
AGCGCGACCTGGGTCTCGCTTGGAGGGTCGGGAGCCGCATAGTAGGCCCGTGCTCGAAATGGCTTCCCAACGGGGTCGTT
TGACGATCGTTATGGCGGTATTTCTCGTGCTTGCGGTGAGCTTAGCTAGCCGTGCTTTGCAACTGCAGGCGATCGAGGCG
CCTGCGTATGCGGCGTCGGCGGCGGCGAGGATGAAGTACACCTACGCTCTTCAGCCCAACCGAGGCGAGCTCACCGATCG
CAATGGCATTGTGATGGCGCAAACCCAGCCTGCGGTATTGGTTTTTGTGGACCCTCGGATGATCTCCCGCAACGGCGTTG
ACGAGCGGGTGACGATGACTCGTGAACAACAGGAGAAGGCAGCCGCTGCGCCTAAGGCCGTCGCGAAGATCCTTGCTACG
CGATTGGGCGGGCAGCCGGAGGATTACCGCAAGGCGGTAACGGCCACTGATGCTAAGGGAAAGCTGAGCCGCTACTCGGT
AGTACGCCACCACGTTGACAGCTACACCTTCGACCTCATCAAGAAGGACATGAAGCAAGGTGGCTGGTACGGAGTATTTA
GTTCAAATGACCCGATCCGTACCTATCCGTCGGGGCAGGTTGCCTCCAACGTCGTGGGCTTCGTGAATGCCGAGGGCAAA
GGAGCTGGCGGTTTCGAATACTCCCATAACAAACAGCTTGCTGGTGTGCCGGGTAAAGAGTCGTATGAGGCCTCGACCTG
GGGCCGTATTCCGCTGGGTTCTAATACTCTGGTGCCTGCGGTCGACGGCACAAGTTACACTCTGACTCTCGACGCTCAGC
TACAGCTGATGGCTCAGCAGGCCCTCGGTACAGCGATTAAGAATGCCAAGGCAAAGAGCGGCGAGATCGTCATGATGGAC
GTGACTAATGGTGAGGTCCTGGCGATGGCGTCAATGCCCACTTTTGACTCAAATAAGCCCGGCAAAGCTAAAGAGAACCA
GACCCGCAATCGGGTCATCCAAGATGCGTACGAGCCAGGATCGGTGCAAAAAGTCCTGACTATGGCTGCGCTGACCGATC
AGGGGATCATCACTCCCGATAGCCACGTCGTCGTTCCGCGTGCTTTGTCGTCTGGTGGCGGCAAGATCACTGATGCTGAG
CCTCACGGCACCGAGTACCTCACCGCCCGTGGGGTGCTAGTGCATTCGTCAAATATTGGGACGGCATTGTTTGCCCGAAA
GTTAGACAAGGCGACCATGGTGTCTTATCTCAAGGCATTCGGGCTAGGGGCTCCTACCCGAATCGGTCTGCCCGGTGAGG
CGAGTGGTCAGATACCGAAGCCCACTATGCCTGACTACACCCGGGACCAGGTTGCGTTCGGCCAGGGGCTGTCAGTGACG
GCTCTTCAGGAGGCCGCTGCCGTTGCCGGAATCGTCAATGGCGGGGTCTACCACTCGCCGACGATTATCAAGTCTGCCGT
TGACGGCCACGGCGAGCCTTCCGAGATTCCTAAGACGACTACCCGCAGAGTGATCTCGCAACGAGCCTCTGAGGAGGTTC
GCGACATGATGGAGAACGTGGTATCTACCGCCAAGGGCCGACCTATTCCGGACTACCGGATGGGTGCCAAGACGGGTACT
GCCCAGCGGATTGACCCTGAGTGTCACTGCTACCACGGGTACATCTCGTCGTTTATTGCCGTCGCTCCTATCGAGAAGCC
GCGTATTCTCACGTACGTTGTCATCAATCAGCCCACCAACGGGCATACTGGCACGGCGGTGGCACAGCCAGCGGCGCGGC
AACTCATGTCTGTTGCCCTGCCGCGATACGGTGTGCAACCGTCCACCGACAAAGCGCGCAAGGAACCCTTGGAGTACCAG
CCGTGA

Upstream 100 bases:

>100_bases
ACCTGCGTACTGGCAAGGTCATCGGAACCCAGACCAAGGTCGACGGCAAGGAGGTACCAGGAGTCATCGGGGAGACGGCT
AAGCCTGAGGTGGGCCAGCC

Downstream 100 bases:

>100_bases
GCCCTGAATCTACTGTCACCCCCACTCCACCTGCTGGTGCTGCCCTCCGACCATCCCAGGGTGATCCTGTCGGGTGGACC
GATCTAGTGGCCTCCTTCGA

Product: cell division protein FtsI/penicillin-binding protein 2

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MSSRHPTGPNSRPGSARRPASNRGPGRARPGSRLEGREPHSRPVLEMASQRGRLTIVMAVFLVLAVSLASRALQLQAIEA
PAYAASAAARMKYTYALQPNRGELTDRNGIVMAQTQPAVLVFVDPRMISRNGVDERVTMTREQQEKAAAAPKAVAKILAT
RLGGQPEDYRKAVTATDAKGKLSRYSVVRHHVDSYTFDLIKKDMKQGGWYGVFSSNDPIRTYPSGQVASNVVGFVNAEGK
GAGGFEYSHNKQLAGVPGKESYEASTWGRIPLGSNTLVPAVDGTSYTLTLDAQLQLMAQQALGTAIKNAKAKSGEIVMMD
VTNGEVLAMASMPTFDSNKPGKAKENQTRNRVIQDAYEPGSVQKVLTMAALTDQGIITPDSHVVVPRALSSGGGKITDAE
PHGTEYLTARGVLVHSSNIGTALFARKLDKATMVSYLKAFGLGAPTRIGLPGEASGQIPKPTMPDYTRDQVAFGQGLSVT
ALQEAAAVAGIVNGGVYHSPTIIKSAVDGHGEPSEIPKTTTRRVISQRASEEVRDMMENVVSTAKGRPIPDYRMGAKTGT
AQRIDPECHCYHGYISSFIAVAPIEKPRILTYVVINQPTNGHTGTAVAQPAARQLMSVALPRYGVQPSTDKARKEPLEYQ
P

Sequences:

>Translated_641_residues
MSSRHPTGPNSRPGSARRPASNRGPGRARPGSRLEGREPHSRPVLEMASQRGRLTIVMAVFLVLAVSLASRALQLQAIEA
PAYAASAAARMKYTYALQPNRGELTDRNGIVMAQTQPAVLVFVDPRMISRNGVDERVTMTREQQEKAAAAPKAVAKILAT
RLGGQPEDYRKAVTATDAKGKLSRYSVVRHHVDSYTFDLIKKDMKQGGWYGVFSSNDPIRTYPSGQVASNVVGFVNAEGK
GAGGFEYSHNKQLAGVPGKESYEASTWGRIPLGSNTLVPAVDGTSYTLTLDAQLQLMAQQALGTAIKNAKAKSGEIVMMD
VTNGEVLAMASMPTFDSNKPGKAKENQTRNRVIQDAYEPGSVQKVLTMAALTDQGIITPDSHVVVPRALSSGGGKITDAE
PHGTEYLTARGVLVHSSNIGTALFARKLDKATMVSYLKAFGLGAPTRIGLPGEASGQIPKPTMPDYTRDQVAFGQGLSVT
ALQEAAAVAGIVNGGVYHSPTIIKSAVDGHGEPSEIPKTTTRRVISQRASEEVRDMMENVVSTAKGRPIPDYRMGAKTGT
AQRIDPECHCYHGYISSFIAVAPIEKPRILTYVVINQPTNGHTGTAVAQPAARQLMSVALPRYGVQPSTDKARKEPLEYQ
P
>Mature_640_residues
SSRHPTGPNSRPGSARRPASNRGPGRARPGSRLEGREPHSRPVLEMASQRGRLTIVMAVFLVLAVSLASRALQLQAIEAP
AYAASAAARMKYTYALQPNRGELTDRNGIVMAQTQPAVLVFVDPRMISRNGVDERVTMTREQQEKAAAAPKAVAKILATR
LGGQPEDYRKAVTATDAKGKLSRYSVVRHHVDSYTFDLIKKDMKQGGWYGVFSSNDPIRTYPSGQVASNVVGFVNAEGKG
AGGFEYSHNKQLAGVPGKESYEASTWGRIPLGSNTLVPAVDGTSYTLTLDAQLQLMAQQALGTAIKNAKAKSGEIVMMDV
TNGEVLAMASMPTFDSNKPGKAKENQTRNRVIQDAYEPGSVQKVLTMAALTDQGIITPDSHVVVPRALSSGGGKITDAEP
HGTEYLTARGVLVHSSNIGTALFARKLDKATMVSYLKAFGLGAPTRIGLPGEASGQIPKPTMPDYTRDQVAFGQGLSVTA
LQEAAAVAGIVNGGVYHSPTIIKSAVDGHGEPSEIPKTTTRRVISQRASEEVRDMMENVVSTAKGRPIPDYRMGAKTGTA
QRIDPECHCYHGYISSFIAVAPIEKPRILTYVVINQPTNGHTGTAVAQPAARQLMSVALPRYGVQPSTDKARKEPLEYQP

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=584, Percent_Identity=30.3082191780822, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1786854, Length=629, Percent_Identity=23.8473767885533, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 68623; Mature: 68492

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRHPTGPNSRPGSARRPASNRGPGRARPGSRLEGREPHSRPVLEMASQRGRLTIVMAV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEHHHHH
FLVLAVSLASRALQLQAIEAPAYAASAAARMKYTYALQPNRGELTDRNGIVMAQTQPAVL
HHHHHHHHHHHHHEEEEECCCHHHHHHHHHEEEEEEECCCCCCCCCCCCEEEEECCCEEE
VFVDPRMISRNGVDERVTMTREQQEKAAAAPKAVAKILATRLGGQPEDYRKAVTATDAKG
EEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
KLSRYSVVRHHVDSYTFDLIKKDMKQGGWYGVFSSNDPIRTYPSGQVASNVVGFVNAEGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCHHHHHEEEEEECCCC
GAGGFEYSHNKQLAGVPGKESYEASTWGRIPLGSNTLVPAVDGTSYTLTLDAQLQLMAQQ
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECHHHHHHHHH
ALGTAIKNAKAKSGEIVMMDVTNGEVLAMASMPTFDSNKPGKAKENQTRNRVIQDAYEPG
HHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCC
SVQKVLTMAALTDQGIITPDSHVVVPRALSSGGGKITDAEPHGTEYLTARGVLVHSSNIG
HHHHHHHHHHHCCCCCCCCCCCEEEEHHHCCCCCEECCCCCCCCEEEEECEEEEECCCCC
TALFARKLDKATMVSYLKAFGLGAPTRIGLPGEASGQIPKPTMPDYTRDQVAFGQGLSVT
HHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHH
ALQEAAAVAGIVNGGVYHSPTIIKSAVDGHGEPSEIPKTTTRRVISQRASEEVRDMMENV
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHH
VSTAKGRPIPDYRMGAKTGTAQRIDPECHCYHGYISSFIAVAPIEKPRILTYVVINQPTN
HHHHCCCCCCCHHCCCCCCCCCCCCCCCEEHHHHHHHHHEECCCCCCCEEEEEEEECCCC
GHTGTAVAQPAARQLMSVALPRYGVQPSTDKARKEPLEYQP
CCCCCHHCCHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
SSRHPTGPNSRPGSARRPASNRGPGRARPGSRLEGREPHSRPVLEMASQRGRLTIVMAV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEHHHHH
FLVLAVSLASRALQLQAIEAPAYAASAAARMKYTYALQPNRGELTDRNGIVMAQTQPAVL
HHHHHHHHHHHHHEEEEECCCHHHHHHHHHEEEEEEECCCCCCCCCCCCEEEEECCCEEE
VFVDPRMISRNGVDERVTMTREQQEKAAAAPKAVAKILATRLGGQPEDYRKAVTATDAKG
EEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
KLSRYSVVRHHVDSYTFDLIKKDMKQGGWYGVFSSNDPIRTYPSGQVASNVVGFVNAEGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCHHHHHEEEEEECCCC
GAGGFEYSHNKQLAGVPGKESYEASTWGRIPLGSNTLVPAVDGTSYTLTLDAQLQLMAQQ
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECHHHHHHHHH
ALGTAIKNAKAKSGEIVMMDVTNGEVLAMASMPTFDSNKPGKAKENQTRNRVIQDAYEPG
HHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCC
SVQKVLTMAALTDQGIITPDSHVVVPRALSSGGGKITDAEPHGTEYLTARGVLVHSSNIG
HHHHHHHHHHHCCCCCCCCCCCEEEEHHHCCCCCEECCCCCCCCEEEEECEEEEECCCCC
TALFARKLDKATMVSYLKAFGLGAPTRIGLPGEASGQIPKPTMPDYTRDQVAFGQGLSVT
HHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHH
ALQEAAAVAGIVNGGVYHSPTIIKSAVDGHGEPSEIPKTTTRRVISQRASEEVRDMMENV
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHH
VSTAKGRPIPDYRMGAKTGTAQRIDPECHCYHGYISSFIAVAPIEKPRILTYVVINQPTN
HHHHCCCCCCCHHCCCCCCCCCCCCCCCEEHHHHHHHHHEECCCCCCCEEEEEEEECCCC
GHTGTAVAQPAARQLMSVALPRYGVQPSTDKARKEPLEYQP
CCCCCHHCCHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]