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The map label for this gene is rsmH

Identifier: 50842237

GI number: 50842237

Start: 823666

End: 824679

Strand: Direct

Name: rsmH

Synonym: PPA0750

Alternate gene names: 50842237

Gene position: 823666-824679 (Clockwise)

Preceding gene: 50842236

Following gene: 50842238

Centisome position: 32.17

GC content: 60.06

Gene sequence:

>1014_bases
ATGCTCATGGCGACCGATGCCATTGGTAGCGATGCTGTCCATATCCCCGTCATGCGTGCCCGTATCCTCGACCTTCTTGC
TGTCGTTCTCAAGAGTGGTCGACGTGTCCATGTTGATGGCACCCTCGGTATGGGAGGTCATGCTGAGGCTGTTCTGAGGC
GATTCCCTGACGTTGAGTTGGTCGGTATCGATCGCGATCAGCAGGCCCTGACAATGGCCGAGGCGCGGCTTGAGCCTTTT
GCAGACCGCGTTCATCTCGTCCACGCTGTTCATGACGAACTTCCTGAGGTGCTTGACGATCTCGGCCTGGACTATGTCGA
CTCCGTACTGCTTGACCTTGGGCTGTCCTCTTTCCAAATTGACGAGGTTGAGCGCGGGTTCTCGTACTCGGTTGATTCCC
CGCTGGACATGCGGATGGACCAGTCCAGTGGTCGTACTGCTGCCCAGATCCTCAATGAGTCTGATCCTGGTGCCTTGGTG
CGTATGCTTCGCGAGTACGGTGAGGAAAAGTTCGCTGACCGCATTGTTCGCGCCATCGTTACCGAACGTGACCGCCAACC
CATCGAGACTTCGGGGCGGCTCGTCGAGATTATTACCGAAGCTATTCCTGCCACAGTGCGTCGCAAGCGCCACAGCCATC
CCGCCAAGCGTACCTTCCAGGCCCTGCGGATTGCCGTTAACCGTGAGATGGAGACCTTGCCCGCGGTGCTCCCGCGAGCT
CTCGATCGTCTTGATGTCGGCGGCCGGATCGCTGTGTTGTCCTATCACTCCCTGGAGGACCGCCCCGTCAAGGAGGCCTT
CCGCGACGCATGCGCGGATACAGCCCCAGCCGGATTGCCGATGGTCCCCGAGTCAATGGCAGCAAAGTTCAACCCTGTTA
CTCGGGGGGCGGAACGTCCCGACGCCGACGAGGTGGCCACCAATCCACGATCCGCCTCGGCACGGTTGCGGGTCATTGAG
CGGGTTCGACCTGGGCCCGTTAACCGTCAGCATGCGACCAAGGAGAGCCGATGA

Upstream 100 bases:

>100_bases
AACTTCCCCTGTGCCAGGTGGTTCAGCCGGAACGGAACCTCGGATCACGGGTCATCGACACCGGTCGAAGACGTTGCTGG
CATATCATGCCGGGGAAGGG

Downstream 100 bases:

>100_bases
GCGCTGAACCAGCACCGCGTCCACAGCAGGCCAGGACTGCTGCTGCACGGCCTACCTCGTTGCGTCCAGTATTGCGTGCA
CTGCCGCAACGGGTGCGTCA

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLMATDAIGSDAVHIPVMRARILDLLAVVLKSGRRVHVDGTLGMGGHAEAVLRRFPDVELVGIDRDQQALTMAEARLEPF
ADRVHLVHAVHDELPEVLDDLGLDYVDSVLLDLGLSSFQIDEVERGFSYSVDSPLDMRMDQSSGRTAAQILNESDPGALV
RMLREYGEEKFADRIVRAIVTERDRQPIETSGRLVEIITEAIPATVRRKRHSHPAKRTFQALRIAVNREMETLPAVLPRA
LDRLDVGGRIAVLSYHSLEDRPVKEAFRDACADTAPAGLPMVPESMAAKFNPVTRGAERPDADEVATNPRSASARLRVIE
RVRPGPVNRQHATKESR

Sequences:

>Translated_337_residues
MLMATDAIGSDAVHIPVMRARILDLLAVVLKSGRRVHVDGTLGMGGHAEAVLRRFPDVELVGIDRDQQALTMAEARLEPF
ADRVHLVHAVHDELPEVLDDLGLDYVDSVLLDLGLSSFQIDEVERGFSYSVDSPLDMRMDQSSGRTAAQILNESDPGALV
RMLREYGEEKFADRIVRAIVTERDRQPIETSGRLVEIITEAIPATVRRKRHSHPAKRTFQALRIAVNREMETLPAVLPRA
LDRLDVGGRIAVLSYHSLEDRPVKEAFRDACADTAPAGLPMVPESMAAKFNPVTRGAERPDADEVATNPRSASARLRVIE
RVRPGPVNRQHATKESR
>Mature_337_residues
MLMATDAIGSDAVHIPVMRARILDLLAVVLKSGRRVHVDGTLGMGGHAEAVLRRFPDVELVGIDRDQQALTMAEARLEPF
ADRVHLVHAVHDELPEVLDDLGLDYVDSVLLDLGLSSFQIDEVERGFSYSVDSPLDMRMDQSSGRTAAQILNESDPGALV
RMLREYGEEKFADRIVRAIVTERDRQPIETSGRLVEIITEAIPATVRRKRHSHPAKRTFQALRIAVNREMETLPAVLPRA
LDRLDVGGRIAVLSYHSLEDRPVKEAFRDACADTAPAGLPMVPESMAAKFNPVTRGAERPDADEVATNPRSASARLRVIE
RVRPGPVNRQHATKESR

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=265, Percent_Identity=41.1320754716981, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI165377202, Length=195, Percent_Identity=38.4615384615385, Blast_Score=118, Evalue=8e-27,
Organism=Escherichia coli, GI1786270, Length=292, Percent_Identity=40.7534246575342, Blast_Score=205, Evalue=3e-54,
Organism=Drosophila melanogaster, GI62472493, Length=333, Percent_Identity=37.2372372372372, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI28571637, Length=333, Percent_Identity=37.2372372372372, Blast_Score=175, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_PROAC (Q6A9R0)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055464.1
- ProteinModelPortal:   Q6A9R0
- SMR:   Q6A9R0
- GeneID:   2931531
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA0750
- NMPDR:   fig|267747.1.peg.741
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- ProtClustDB:   CLSK2763499
- BioCyc:   PACN267747:PPA0750-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 37301; Mature: 37301

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: BINDING 64-64 BINDING 91-91 BINDING 112-112 BINDING 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMATDAIGSDAVHIPVMRARILDLLAVVLKSGRRVHVDGTLGMGGHAEAVLRRFPDVEL
CEEECCCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHCCCCEE
VGIDRDQQALTMAEARLEPFADRVHLVHAVHDELPEVLDDLGLDYVDSVLLDLGLSSFQI
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCH
DEVERGFSYSVDSPLDMRMDQSSGRTAAQILNESDPGALVRMLREYGEEKFADRIVRAIV
HHHHCCCCCCCCCCHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TERDRQPIETSGRLVEIITEAIPATVRRKRHSHPAKRTFQALRIAVNREMETLPAVLPRA
HHCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRLDVGGRIAVLSYHSLEDRPVKEAFRDACADTAPAGLPMVPESMAAKFNPVTRGAERP
HHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHCCCCCC
DADEVATNPRSASARLRVIERVRPGPVNRQHATKESR
CHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLMATDAIGSDAVHIPVMRARILDLLAVVLKSGRRVHVDGTLGMGGHAEAVLRRFPDVEL
CEEECCCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHCCCCEE
VGIDRDQQALTMAEARLEPFADRVHLVHAVHDELPEVLDDLGLDYVDSVLLDLGLSSFQI
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCH
DEVERGFSYSVDSPLDMRMDQSSGRTAAQILNESDPGALVRMLREYGEEKFADRIVRAIV
HHHHCCCCCCCCCCHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TERDRQPIETSGRLVEIITEAIPATVRRKRHSHPAKRTFQALRIAVNREMETLPAVLPRA
HHCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRLDVGGRIAVLSYHSLEDRPVKEAFRDACADTAPAGLPMVPESMAAKFNPVTRGAERP
HHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHCCCCCC
DADEVATNPRSASARLRVIERVRPGPVNRQHATKESR
CHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA