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The map label for this gene is 50842224

Identifier: 50842224

GI number: 50842224

Start: 808957

End: 809415

Strand: Direct

Name: 50842224

Synonym: PPA0737

Alternate gene names: NA

Gene position: 808957-809415 (Clockwise)

Preceding gene: 50842223

Following gene: 50842227

Centisome position: 31.6

GC content: 61.44

Gene sequence:

>459_bases
GTGACTCGTACTTTTGACCCCATCCGTGAAATGGACCGGCTGCTCTCCGACGTCACCAGGACGCCGGCGACTGTCGCCGT
TCCCATGGATCTCTACCGTGAAGGGGATGACTACACCGTCGCCGTGGACCTTCCAGGAGTTGATCCAGCGTCCATTGATA
TCGATGTCGACGATCGCACATTGACGATTCGCGCCGAGCGTGCCGCCAAGGTGGCTAAGGAGGCGCAGTGGCTGTCCCGT
GAGCGGGCTATGGGCACCTTCGCCCGTCAACTCACCCTCGGTCATGGCCTGGCTACCGATCGCATCACCGCCGAGTACAC
CGACGGCGTGCTGACCTTGACGATCCCCGTAGCTGAGACTGCTAAGCCTCGCAAGGTAGAGGTCCGACATGGCTCGACCA
CCATCGACGCCATGACCGACCAGGCTCAGGTCGGTTCAGGTGAGCACCAGGAACAGTGA

Upstream 100 bases:

>100_bases
CAACTTGGTTATTGAGCCGGGGTGCTCATGGTTAAACTTGAGTCATAACGACTCAAACCGAGTCGAGGTAGGAATCTGCT
GAAGCCGTAGGAGTGTTGAC

Downstream 100 bases:

>100_bases
CGTTCTCAGATTGACGTGACGGCCGGTTCCTTCATCCGGGGACCGGCCGTCGCGCGTCAGGTATCGGTGAGGTCAGACGA
TGACGGAGACCAGCAGCACC

Product: 18 kDa antigen 2

Products: NA

Alternate protein names: Clone MAVC83 [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MTRTFDPIREMDRLLSDVTRTPATVAVPMDLYREGDDYTVAVDLPGVDPASIDIDVDDRTLTIRAERAAKVAKEAQWLSR
ERAMGTFARQLTLGHGLATDRITAEYTDGVLTLTIPVAETAKPRKVEVRHGSTTIDAMTDQAQVGSGEHQEQ

Sequences:

>Translated_152_residues
MTRTFDPIREMDRLLSDVTRTPATVAVPMDLYREGDDYTVAVDLPGVDPASIDIDVDDRTLTIRAERAAKVAKEAQWLSR
ERAMGTFARQLTLGHGLATDRITAEYTDGVLTLTIPVAETAKPRKVEVRHGSTTIDAMTDQAQVGSGEHQEQ
>Mature_151_residues
TRTFDPIREMDRLLSDVTRTPATVAVPMDLYREGDDYTVAVDLPGVDPASIDIDVDDRTLTIRAERAAKVAKEAQWLSRE
RAMGTFARQLTLGHGLATDRITAEYTDGVLTLTIPVAETAKPRKVEVRHGSTTIDAMTDQAQVGSGEHQEQ

Specific function: Not known. This protein is one of the major immune reactive proteins in mycobacteria [H]

COG id: COG0071

COG function: function code O; Molecular chaperone (small heat shock protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small heat shock protein (HSP20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002068
- InterPro:   IPR008978 [H]

Pfam domain/function: PF00011 HSP20 [H]

EC number: NA

Molecular weight: Translated: 16740; Mature: 16609

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS01031 HSP20

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTFDPIREMDRLLSDVTRTPATVAVPMDLYREGDDYTVAVDLPGVDPASIDIDVDDRT
CCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHCCCCCEEEEEECCCCCCCEEEEEECCCE
LTIRAERAAKVAKEAQWLSRERAMGTFARQLTLGHGLATDRITAEYTDGVLTLTIPVAET
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEECCCC
AKPRKVEVRHGSTTIDAMTDQAQVGSGEHQEQ
CCCCEEEEECCCEEEECCCCCHHCCCCCCCCC
>Mature Secondary Structure 
TRTFDPIREMDRLLSDVTRTPATVAVPMDLYREGDDYTVAVDLPGVDPASIDIDVDDRT
CCCHHHHHHHHHHHHHHHCCCCEEEECHHHHCCCCCEEEEEECCCCCCCEEEEEECCCE
LTIRAERAAKVAKEAQWLSRERAMGTFARQLTLGHGLATDRITAEYTDGVLTLTIPVAET
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEECCCC
AKPRKVEVRHGSTTIDAMTDQAQVGSGEHQEQ
CCCCEEEEECCCEEEECCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8454357 [H]