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The map label for this gene is aroB [H]

Identifier: 50842032

GI number: 50842032

Start: 601628

End: 602560

Strand: Direct

Name: aroB [H]

Synonym: PPA0548

Alternate gene names: 50842032

Gene position: 601628-602560 (Clockwise)

Preceding gene: 50842031

Following gene: 50842033

Centisome position: 23.5

GC content: 60.24

Gene sequence:

>933_bases
ATGAGCGGCAGCCACACCGTTGCAGCTATCGACTGCGGGACGAATTCGATTCGCCTCCTCATCGCATCAGCCGATTCGGA
CGGGCGTTTGGTCGAGCAGGCACGAGAACTGGAAATGGTGAGGCTCGGTCAGGGGGTTGACGCCACCGGTTCCTTCCGTC
CGGACGCCCTTGAGCGCACTTTCTCAGCCTGTCGCACCTTCGCCCAGGCTATCGCGGACCACCACTGCGACCGGGTGCGT
TTTGTTGCCACCTCGGCTGCTCGTGACGTCTCCAACCGCGATGCCTTTTTCGCGGGAGTCCGTCAAGCTCTGGGGGTGGA
CGCGGAGGTCATAGACGGCATGGAAGAGGCGAGTTTGTCTTTTGCTGGAGCGATTTCTGGGATCCAGGTAATCGATGAGC
CGGTTCTTGTTATTGATTGTGGAGGTGGCTCGACGGAGCTGGTGCTGGGCCGTGGGTCTAGCATCGACTCTCGGGTGAGC
CTCAATATTGGCTCGGTACGGCTGCGTGAGCGTTTCCTCCATGACGACCCGCCCACCGTCGAGCAGATCGACGACGCTCG
CAAGTACGTTCGTGAAGCCTTGGATTCCTGCCCGGTTGACGTTGCCGCCGCCCGTACCGTCATCGGCGTTGCGGGTACGG
TCACGAGCTTGTCCGCAATTGGCCAGAATCTCACAGATTATGACCGCGCCAAGGTGCATCGTTCGGTACTGACGGTCGGC
CAGATTTCCGACCTGGCGGGCAAGTTGCTCTCGTCTACTGTTGATGAGGTCGAGCAGATGGGACCGCTGAAGCGACGCCG
TGCAGAAGTGTTGTGTGGAGGTGCCGTTATTATTGACGAGGTATGCCGTCGTGCGACGGCAGGTAAACTTGTCGTCTCGG
AGACCGATATCCTTGACGGCATGGCGCTGGCAATGCTGGCGCAGGGGAGCTGA

Upstream 100 bases:

>100_bases
TCAACCCGTTTGGGGATGAGGTCGTTGCAGAGCTGGGAGAGTTCTGGTGCGACCCATGCGCCCCTGAGCATCGCGAGCCC
GAGTCGGACAGGAGGATTGT

Downstream 100 bases:

>100_bases
AGTGCTCCTGGCCCCCGTAGCCCAACCGGCAGAGGCAGACGGCTTAAACCCGTCCCAGTGCGGGTTCGAATCCCGTCGGG
GGTACACAGCTTCACCAGGA

Product: Ppx/GppA phosphatase family hydrolase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSGSHTVAAIDCGTNSIRLLIASADSDGRLVEQARELEMVRLGQGVDATGSFRPDALERTFSACRTFAQAIADHHCDRVR
FVATSAARDVSNRDAFFAGVRQALGVDAEVIDGMEEASLSFAGAISGIQVIDEPVLVIDCGGGSTELVLGRGSSIDSRVS
LNIGSVRLRERFLHDDPPTVEQIDDARKYVREALDSCPVDVAAARTVIGVAGTVTSLSAIGQNLTDYDRAKVHRSVLTVG
QISDLAGKLLSSTVDEVEQMGPLKRRRAEVLCGGAVIIDEVCRRATAGKLVVSETDILDGMALAMLAQGS

Sequences:

>Translated_310_residues
MSGSHTVAAIDCGTNSIRLLIASADSDGRLVEQARELEMVRLGQGVDATGSFRPDALERTFSACRTFAQAIADHHCDRVR
FVATSAARDVSNRDAFFAGVRQALGVDAEVIDGMEEASLSFAGAISGIQVIDEPVLVIDCGGGSTELVLGRGSSIDSRVS
LNIGSVRLRERFLHDDPPTVEQIDDARKYVREALDSCPVDVAAARTVIGVAGTVTSLSAIGQNLTDYDRAKVHRSVLTVG
QISDLAGKLLSSTVDEVEQMGPLKRRRAEVLCGGAVIIDEVCRRATAGKLVVSETDILDGMALAMLAQGS
>Mature_309_residues
SGSHTVAAIDCGTNSIRLLIASADSDGRLVEQARELEMVRLGQGVDATGSFRPDALERTFSACRTFAQAIADHHCDRVRF
VATSAARDVSNRDAFFAGVRQALGVDAEVIDGMEEASLSFAGAISGIQVIDEPVLVIDCGGGSTELVLGRGSSIDSRVSL
NIGSVRLRERFLHDDPPTVEQIDDARKYVREALDSCPVDVAAARTVIGVAGTVTSLSAIGQNLTDYDRAKVHRSVLTVGQ
ISDLAGKLLSSTVDEVEQMGPLKRRRAEVLCGGAVIIDEVCRRATAGKLVVSETDILDGMALAMLAQGS

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=221, Percent_Identity=33.9366515837104, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788848, Length=224, Percent_Identity=25.8928571428571, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 32757; Mature: 32626

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSHTVAAIDCGTNSIRLLIASADSDGRLVEQARELEMVRLGQGVDATGSFRPDALERT
CCCCCEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
FSACRTFAQAIADHHCDRVRFVATSAARDVSNRDAFFAGVRQALGVDAEVIDGMEEASLS
HHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHH
FAGAISGIQVIDEPVLVIDCGGGSTELVLGRGSSIDSRVSLNIGSVRLRERFLHDDPPTV
HHHHHCCHHEECCCEEEEECCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHCCCCCHH
EQIDDARKYVREALDSCPVDVAAARTVIGVAGTVTSLSAIGQNLTDYDRAKVHRSVLTVG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QISDLAGKLLSSTVDEVEQMGPLKRRRAEVLCGGAVIIDEVCRRATAGKLVVSETDILDG
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECHHHHHH
MALAMLAQGS
HHHHHHHCCC
>Mature Secondary Structure 
SGSHTVAAIDCGTNSIRLLIASADSDGRLVEQARELEMVRLGQGVDATGSFRPDALERT
CCCCEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
FSACRTFAQAIADHHCDRVRFVATSAARDVSNRDAFFAGVRQALGVDAEVIDGMEEASLS
HHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHH
FAGAISGIQVIDEPVLVIDCGGGSTELVLGRGSSIDSRVSLNIGSVRLRERFLHDDPPTV
HHHHHCCHHEECCCEEEEECCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHCCCCCHH
EQIDDARKYVREALDSCPVDVAAARTVIGVAGTVTSLSAIGQNLTDYDRAKVHRSVLTVG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QISDLAGKLLSSTVDEVEQMGPLKRRRAEVLCGGAVIIDEVCRRATAGKLVVSETDILDG
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECHHHHHH
MALAMLAQGS
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]