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The map label for this gene is clpC [H]

Identifier: 50841767

GI number: 50841767

Start: 326692

End: 329226

Strand: Direct

Name: clpC [H]

Synonym: PPA0278

Alternate gene names: 50841767

Gene position: 326692-329226 (Clockwise)

Preceding gene: 50841766

Following gene: 50841771

Centisome position: 12.76

GC content: 60.75

Gene sequence:

>2535_bases
ATGTTCGAACGGTTCACCGATCGGGCCCGCCGGGTCGTCGTCCTGGCCCAGGATGAGGCCAAGGCCCTGAACCACAATTA
CATTGGCACTGAGCACCTGCTGCTCGGGCTCATTAGCGAGGGCGAGGGAGTCGCTGCCAAGGCTCTCGAGTCCCTTGACA
TTTCACTGGAGGCTGTTCGCGCCCAGGTGGAGGAGATTATTGGTCACGGCACTTCGACGCCGACGGGCCATATTCCCTTT
ACCCCGCGTGCCAAGAAGGTTCTTGAGCTGAGCCTGCGCGAAGCCCTCCAGATGAATCATTCGTACATTGGCACCGAGCA
CATTCTGCTTGGCCTTATCCGGGAGGGAGAAGGCGTCGCTGCTCAGGTACTGATCCGGCTGGGTGCTGACCTCAACACGG
TGCGCAATAGCGTCTTGCAACTGTTGCAGGGATATCAGGGCGACGAGCGTCAGGCCGCCACTTCCGGTGCCCCCGAGGCC
GGACCGCAGCAGTCCTCGGCGACGATTCTTGACCAATTCGGTCGCAACCTTACCGAGGCCGCCCGCGACGGCGAGCTCGA
CCCGGTTATCGGGCGTGAGAGGGAAATCGAACGAGTCATGGTGGTGCTGAGCCGGCGCACCAAGAATAACCCGGTTCTTA
TTGGTGAGCCTGGCGTCGGTAAGTCTGCTTGTGTCGAGGGCCTGGCTCAGGCCATCGTGCGTGGAGACGTTCCCGAGACT
CTGCGTGACAAGAAGATTTACTCCCTGGACCTTGGCTCCATGGTTGCGGGATCGCGTTACCGCGGTGATTTCGAGGAGAG
GATGAAGAAGGTCCTCAAGGAGATAAAAAATCGCGGGGACATCATCCTGTTCATCGACGAGATCCACACCCTTGTCGGCG
CCGGTGCCGCTGAAGGGGCAATCGACGCTGCCAGCATGCTCAAGCCGATGCTGGCTCGCGGCGAGCTGCAGACTATCGGT
GCGACGACCCTTGATGAGTACCGTAAGTACATCGAGAAGGACGCCGCCCTGGAGCGTCGCTTCCAGCCGATCCAGGTAGA
CGAGCCCTCGATCCCCCTGGCCATCGAGATCCTTAAGGGTCTGCGCGACCGGTACGAGGCCCACCACAAGATCACCATCA
CCGACGAGGCAATCACCTCCGCAGCGAATCTTGCGTCCCGTTACATCCAAGACCGCTTCCTGCCAGACAAGGCCATCGAT
CTCATTGACGAGGCCGGTGCCCGGATGAACATCCGCCGCATGACGGCCCCGCCGGATCTGCGCGAGTTCGACGAGCGGAT
TGCTCGTGTGCGAGTGGAGAAAGAGGCCGCCATCGACGCCCAGGATTTCGAGCGTGCTGCTGGGCTGCGCGACGACGAAA
AGAAACTTCTCGCCGAGCGTGAGGCCAAGGAGGAGGAGTGGAAGCAGGGTGACGAGTCGGTGCCAGCCGTGGTCGGCCCT
GATGAGATCGCCGAGGTGCTCTCTGGAGCTACCGGAATTCCGGTCTTCAAGCTCACGGAGGAGGAATCCCAGCGTCTGCT
CCACATGGAGGACGAGATCGGCAAGCGTTACGTCGGCCAGGAGGACGCCGTTAAGGCCCTGTGCCGCTCTATCCGACGTA
CCCGTGCCGGCCTCAAGGACCCGAAGCGTCCGGCAGGTTCGTTCATTTTTGCTGGCCCGTCGGGTGTTGGTAAGACCGAG
CTCACCAAGGCGCTCACCGAGTTCCTCTTTGGCGACGAGGACGCCCTCATCACCCTCGACATGAGCGAGTACTCCGAGAA
ACACACCGCTTCGCGGATGTTTGGGTCCCCGCCTGGATTCGTCGGGTACGAGGAGGGCGGCCAGCTCACCGAGAAGGTGC
GCCGCAAGCCGTTCAGCGTCATTCTCTTTGACGAGATTGAAAAGGCCCACCCCGATATCTTCAACTCTCTGTTGCAGATT
CTTGACGAGGGACGTCTTACTGACGCCCAGGGCCGTGTAGTGGACTTTAAGAACACCGTCATTGTGCTGACGACCAACCT
TGGCACCCGCGACATTTCCAAATCAGTCAATCTCGGCTTTTCCAAGGCCGACGACGTCGAGTCTAGCTACGAGAAGATGA
AGGCCAAGGTTACCGAGGAGCTCAAGGGACACTTCCGTCCCGAGTTCCTCAACCGCCTTGACGAGATCATCGTCTTCCAT
CAGCTCACCCAGCCCGACATCCTACGGATTGTCGACCTCATGGTGGGGCAACTGGAGGATCGTCTGGCCGACAAGGACAT
GGGTATCGAGGTCACTCCGGCTGCCAAGGAACTGCTGTCCACGCGTGGTTTCGACCCGCTGCTCGGTGCTCGTCCGCTGC
GCCGGACGATCCAGCGCGACATCGAGGACGTCCTAGCCGAGAAGATCCTCTTCGGGGAGGTCAAACCTGGTCAGATCGTG
GTGGTCGATGCTGCCCCGGAGGGTTCCGAGGAGCCGTTCGTCTTCACCGGCACGGAGCGCTCAGAGCTGCCTGACGAGGT
TCCTCCTGAGCTCACCTCTTCGGCAGGGGAAAATAACAGGGGGCAGCAGGGCTGA

Upstream 100 bases:

>100_bases
AGTGCCGTCGGTTGGTTGCATGAAAGTTTCACGCGACCGCGGGTAGATCGGTCATCCGGTATTTCCGGGGATTGGTCTGC
CCCACATACAAGGAGAGTTC

Downstream 100 bases:

>100_bases
TTCCCTGATAACGATGGCCGTGGCCCGGTGCATTATGCGCCGGGCCCGTTCCTCACACCAGCACCGCCTGCAGGGCGAAG
GACACCAACCAGTGAGTAGC

Product: Clp family ATP-binding protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 844; Mature: 844

Protein sequence:

>844_residues
MFERFTDRARRVVVLAQDEAKALNHNYIGTEHLLLGLISEGEGVAAKALESLDISLEAVRAQVEEIIGHGTSTPTGHIPF
TPRAKKVLELSLREALQMNHSYIGTEHILLGLIREGEGVAAQVLIRLGADLNTVRNSVLQLLQGYQGDERQAATSGAPEA
GPQQSSATILDQFGRNLTEAARDGELDPVIGREREIERVMVVLSRRTKNNPVLIGEPGVGKSACVEGLAQAIVRGDVPET
LRDKKIYSLDLGSMVAGSRYRGDFEERMKKVLKEIKNRGDIILFIDEIHTLVGAGAAEGAIDAASMLKPMLARGELQTIG
ATTLDEYRKYIEKDAALERRFQPIQVDEPSIPLAIEILKGLRDRYEAHHKITITDEAITSAANLASRYIQDRFLPDKAID
LIDEAGARMNIRRMTAPPDLREFDERIARVRVEKEAAIDAQDFERAAGLRDDEKKLLAEREAKEEEWKQGDESVPAVVGP
DEIAEVLSGATGIPVFKLTEEESQRLLHMEDEIGKRYVGQEDAVKALCRSIRRTRAGLKDPKRPAGSFIFAGPSGVGKTE
LTKALTEFLFGDEDALITLDMSEYSEKHTASRMFGSPPGFVGYEEGGQLTEKVRRKPFSVILFDEIEKAHPDIFNSLLQI
LDEGRLTDAQGRVVDFKNTVIVLTTNLGTRDISKSVNLGFSKADDVESSYEKMKAKVTEELKGHFRPEFLNRLDEIIVFH
QLTQPDILRIVDLMVGQLEDRLADKDMGIEVTPAAKELLSTRGFDPLLGARPLRRTIQRDIEDVLAEKILFGEVKPGQIV
VVDAAPEGSEEPFVFTGTERSELPDEVPPELTSSAGENNRGQQG

Sequences:

>Translated_844_residues
MFERFTDRARRVVVLAQDEAKALNHNYIGTEHLLLGLISEGEGVAAKALESLDISLEAVRAQVEEIIGHGTSTPTGHIPF
TPRAKKVLELSLREALQMNHSYIGTEHILLGLIREGEGVAAQVLIRLGADLNTVRNSVLQLLQGYQGDERQAATSGAPEA
GPQQSSATILDQFGRNLTEAARDGELDPVIGREREIERVMVVLSRRTKNNPVLIGEPGVGKSACVEGLAQAIVRGDVPET
LRDKKIYSLDLGSMVAGSRYRGDFEERMKKVLKEIKNRGDIILFIDEIHTLVGAGAAEGAIDAASMLKPMLARGELQTIG
ATTLDEYRKYIEKDAALERRFQPIQVDEPSIPLAIEILKGLRDRYEAHHKITITDEAITSAANLASRYIQDRFLPDKAID
LIDEAGARMNIRRMTAPPDLREFDERIARVRVEKEAAIDAQDFERAAGLRDDEKKLLAEREAKEEEWKQGDESVPAVVGP
DEIAEVLSGATGIPVFKLTEEESQRLLHMEDEIGKRYVGQEDAVKALCRSIRRTRAGLKDPKRPAGSFIFAGPSGVGKTE
LTKALTEFLFGDEDALITLDMSEYSEKHTASRMFGSPPGFVGYEEGGQLTEKVRRKPFSVILFDEIEKAHPDIFNSLLQI
LDEGRLTDAQGRVVDFKNTVIVLTTNLGTRDISKSVNLGFSKADDVESSYEKMKAKVTEELKGHFRPEFLNRLDEIIVFH
QLTQPDILRIVDLMVGQLEDRLADKDMGIEVTPAAKELLSTRGFDPLLGARPLRRTIQRDIEDVLAEKILFGEVKPGQIV
VVDAAPEGSEEPFVFTGTERSELPDEVPPELTSSAGENNRGQQG
>Mature_844_residues
MFERFTDRARRVVVLAQDEAKALNHNYIGTEHLLLGLISEGEGVAAKALESLDISLEAVRAQVEEIIGHGTSTPTGHIPF
TPRAKKVLELSLREALQMNHSYIGTEHILLGLIREGEGVAAQVLIRLGADLNTVRNSVLQLLQGYQGDERQAATSGAPEA
GPQQSSATILDQFGRNLTEAARDGELDPVIGREREIERVMVVLSRRTKNNPVLIGEPGVGKSACVEGLAQAIVRGDVPET
LRDKKIYSLDLGSMVAGSRYRGDFEERMKKVLKEIKNRGDIILFIDEIHTLVGAGAAEGAIDAASMLKPMLARGELQTIG
ATTLDEYRKYIEKDAALERRFQPIQVDEPSIPLAIEILKGLRDRYEAHHKITITDEAITSAANLASRYIQDRFLPDKAID
LIDEAGARMNIRRMTAPPDLREFDERIARVRVEKEAAIDAQDFERAAGLRDDEKKLLAEREAKEEEWKQGDESVPAVVGP
DEIAEVLSGATGIPVFKLTEEESQRLLHMEDEIGKRYVGQEDAVKALCRSIRRTRAGLKDPKRPAGSFIFAGPSGVGKTE
LTKALTEFLFGDEDALITLDMSEYSEKHTASRMFGSPPGFVGYEEGGQLTEKVRRKPFSVILFDEIEKAHPDIFNSLLQI
LDEGRLTDAQGRVVDFKNTVIVLTTNLGTRDISKSVNLGFSKADDVESSYEKMKAKVTEELKGHFRPEFLNRLDEIIVFH
QLTQPDILRIVDLMVGQLEDRLADKDMGIEVTPAAKELLSTRGFDPLLGARPLRRTIQRDIEDVLAEKILFGEVKPGQIV
VVDAAPEGSEEPFVFTGTERSELPDEVPPELTSSAGENNRGQQG

Specific function: Part Of A Stress-Induced Multi-Chaperone System, It Is Involved In The Recovery Of The Cell From Heat-Induced Damage, In Cooperation With Dnak, Dnaj And Grpe. Acts Before Dnak, In The Processing Of Protein Aggregates. Protein Binding Stimulates The Atpase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=33.2214765100671, Blast_Score=182, Evalue=9e-46,
Organism=Escherichia coli, GI1788943, Length=873, Percent_Identity=43.298969072165, Blast_Score=668, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=824, Percent_Identity=38.7135922330097, Blast_Score=525, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6320464, Length=703, Percent_Identity=46.6571834992888, Blast_Score=603, Evalue=1e-173,
Organism=Saccharomyces cerevisiae, GI6323002, Length=347, Percent_Identity=42.9394812680115, Blast_Score=291, Evalue=2e-79,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 93311; Mature: 93311

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50151 UVR ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTDRARRVVVLAQDEAKALNHNYIGTEHLLLGLISEGEGVAAKALESLDISLEAVR
CCCHHHHHCCEEEEEECCHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AQVEEIIGHGTSTPTGHIPFTPRAKKVLELSLREALQMNHSYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCHH
AQVLIRLGADLNTVRNSVLQLLQGYQGDERQAATSGAPEAGPQQSSATILDQFGRNLTEA
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHH
ARDGELDPVIGREREIERVMVVLSRRTKNNPVLIGEPGVGKSACVEGLAQAIVRGDVPET
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHH
LRDKKIYSLDLGSMVAGSRYRGDFEERMKKVLKEIKNRGDIILFIDEIHTLVGAGAAEGA
HHCCEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCH
IDAASMLKPMLARGELQTIGATTLDEYRKYIEKDAALERRFQPIQVDEPSIPLAIEILKG
HHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
LRDRYEAHHKITITDEAITSAANLASRYIQDRFLPDKAIDLIDEAGARMNIRRMTAPPDL
HHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCH
REFDERIARVRVEKEAAIDAQDFERAAGLRDDEKKLLAEREAKEEEWKQGDESVPAVVGP
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECH
DEIAEVLSGATGIPVFKLTEEESQRLLHMEDEIGKRYVGQEDAVKALCRSIRRTRAGLKD
HHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
PKRPAGSFIFAGPSGVGKTELTKALTEFLFGDEDALITLDMSEYSEKHTASRMFGSPPGF
CCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCC
VGYEEGGQLTEKVRRKPFSVILFDEIEKAHPDIFNSLLQILDEGRLTDAQGRVVDFKNTV
CCCCCCCHHHHHHHHCCCEEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEECCEE
IVLTTNLGTRDISKSVNLGFSKADDVESSYEKMKAKVTEELKGHFRPEFLNRLDEIIVFH
EEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QLTQPDILRIVDLMVGQLEDRLADKDMGIEVTPAAKELLSTRGFDPLLGARPLRRTIQRD
HCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHH
IEDVLAEKILFGEVKPGQIVVVDAAPEGSEEPFVFTGTERSELPDEVPPELTSSAGENNR
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCHHCCCCCCCCHHHHCCCCCCC
GQQG
CCCC
>Mature Secondary Structure
MFERFTDRARRVVVLAQDEAKALNHNYIGTEHLLLGLISEGEGVAAKALESLDISLEAVR
CCCHHHHHCCEEEEEECCHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AQVEEIIGHGTSTPTGHIPFTPRAKKVLELSLREALQMNHSYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCHH
AQVLIRLGADLNTVRNSVLQLLQGYQGDERQAATSGAPEAGPQQSSATILDQFGRNLTEA
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHH
ARDGELDPVIGREREIERVMVVLSRRTKNNPVLIGEPGVGKSACVEGLAQAIVRGDVPET
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHH
LRDKKIYSLDLGSMVAGSRYRGDFEERMKKVLKEIKNRGDIILFIDEIHTLVGAGAAEGA
HHCCEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCH
IDAASMLKPMLARGELQTIGATTLDEYRKYIEKDAALERRFQPIQVDEPSIPLAIEILKG
HHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
LRDRYEAHHKITITDEAITSAANLASRYIQDRFLPDKAIDLIDEAGARMNIRRMTAPPDL
HHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCH
REFDERIARVRVEKEAAIDAQDFERAAGLRDDEKKLLAEREAKEEEWKQGDESVPAVVGP
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECH
DEIAEVLSGATGIPVFKLTEEESQRLLHMEDEIGKRYVGQEDAVKALCRSIRRTRAGLKD
HHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
PKRPAGSFIFAGPSGVGKTELTKALTEFLFGDEDALITLDMSEYSEKHTASRMFGSPPGF
CCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCC
VGYEEGGQLTEKVRRKPFSVILFDEIEKAHPDIFNSLLQILDEGRLTDAQGRVVDFKNTV
CCCCCCCHHHHHHHHCCCEEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEECCEE
IVLTTNLGTRDISKSVNLGFSKADDVESSYEKMKAKVTEELKGHFRPEFLNRLDEIIVFH
EEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QLTQPDILRIVDLMVGQLEDRLADKDMGIEVTPAAKELLSTRGFDPLLGARPLRRTIQRD
HCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHH
IEDVLAEKILFGEVKPGQIVVVDAAPEGSEEPFVFTGTERSELPDEVPPELTSSAGENNR
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCHHCCCCCCCCHHHHCCCCCCC
GQQG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]