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The map label for this gene is 50841742

Identifier: 50841742

GI number: 50841742

Start: 304329

End: 305678

Strand: Direct

Name: 50841742

Synonym: PPA0250

Alternate gene names: NA

Gene position: 304329-305678 (Clockwise)

Preceding gene: 50841740

Following gene: 50841743

Centisome position: 11.89

GC content: 60.89

Gene sequence:

>1350_bases
ATGTACGACAGCATCATCATTGGCGCGGGTCTAGCCGGACTCACGGCTGCTGAAGAGCTCGCCTCCGCAGGACACTCGGT
GGTGGTCCTGGAGGCCCGAGCCCGGGTAGGCGGCCGCTTGGAAAACGCCGAGTTATCCAACGGGCAGGTCGTTGAACTGG
GTGGCCAGTGGGTTGGAGAAGGGCATGAGGAACTTCGCTCCCTCCTCTCCTCACAAGGGTTAGAACTGGTTGATTCAACC
GACGGCGACGTCGTTGTCAAGGCCAGGGGCAGGGTCTCTCACGTCACAAGTTTGTCCGAGCCGTCCGCTCATTCCCTTAG
CCCCTTCGAATTGGCTGACCTCGGCCAGGGCCTGCTGAGGTTCCGTCGTCTGGCCGATCGTGTTGCCAATAACAAGGGCT
GGGCGGCGGCCAATGCCACCTGGTTGAACCAGTCGTTGAGTCAATGGACAGTCTCGAATGTTCGTACCGAGGCCGGTCGT
GGCTACATCACGAACCTCTTCCGTCAAGCCTTCGGTGTGTCTGCCAATGACACTCCTCTCTTCAACGGTCTGGCTAAGGC
CAACGCCGGTGTGGACTTGGAATCCCTCGTCGCCGTCAACGGTGGCCTTAAGCAGCAGCGCGTTAAGGGCGGGGTTGCTC
AGGTTACCCGTAACCTCGCTGAGCCTCTCGGTGACGATCTTAAACTCTCCAGCCCGGTCCGATCCGTTCATAGTGACGAC
GACGGCGTTACCGTCACCACTACTGATGGCACGCAGTATCAGGGACGTAGCGTCATCGTCACCGTGCCGCCGCGGCTACT
TAAGGACATGACATTCGAGCCAGCGCTGCCTGCTGAGCGTCTCGAGATGGCCGACAAAGTGCCAGCTGGCAATGTCATCA
AGGCCTACCTCGTTTATGACAGCCCATGGTGGCGCACCTCTGGTGCTTCCGGCCAGATGGGTGCTGACGAGGGCGCTGTC
CGTGTCATTTTTGATACTTCTGACGACGAGACCGGCAAGGGAATCCTCATGGGCTTCTTCGAGGGCACCGAGGCTTCCGG
CTACGGGAAACTTTCGGTCGGTCTGCGTCAACGTGCCTTCGAAGAGGTCGTCGAGTCGGCCTTCGGCAAGGCCCCCAGCT
CGCCGATCGAGTACCTTGATCGCGACTGGCTCTCTGAGCCTTACACCGGCGGATGCCACGGAGCCCACTTCGCTCCCAGT
CTGTGGACGACTACGGGGCCGATCCTTGCCGAGCCGCTGGGCCGGGTGTTTTTCGCGGGGGCTGAGTACGCCTCTTCCTT
CAACGGTTATATGGAGGGCGCACTGCGCGCTGCTGCTCGCGCTGCTCAGGAGGTCCTCGACCTGCTCTGA

Upstream 100 bases:

>100_bases
CCAGCTCGTCAGAGGCGCCAGGTACGATCAACTCACCACGATTCATCGATCACGGTCCGGCCATGAGTTCGGTCCGTCCA
GCGGAATTGCAAGGGGACGC

Downstream 100 bases:

>100_bases
GCCAAGACGATCAGCCACTGACTTCTTCTGCGGCGAACCGTGCCACGAGGCCAGCGTCAGAGGGTTGTATCGCGGCGACT
CCCATCGCTGACTTCAGCCT

Product: putative flavin-containing amine oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MYDSIIIGAGLAGLTAAEELASAGHSVVVLEARARVGGRLENAELSNGQVVELGGQWVGEGHEELRSLLSSQGLELVDST
DGDVVVKARGRVSHVTSLSEPSAHSLSPFELADLGQGLLRFRRLADRVANNKGWAAANATWLNQSLSQWTVSNVRTEAGR
GYITNLFRQAFGVSANDTPLFNGLAKANAGVDLESLVAVNGGLKQQRVKGGVAQVTRNLAEPLGDDLKLSSPVRSVHSDD
DGVTVTTTDGTQYQGRSVIVTVPPRLLKDMTFEPALPAERLEMADKVPAGNVIKAYLVYDSPWWRTSGASGQMGADEGAV
RVIFDTSDDETGKGILMGFFEGTEASGYGKLSVGLRQRAFEEVVESAFGKAPSSPIEYLDRDWLSEPYTGGCHGAHFAPS
LWTTTGPILAEPLGRVFFAGAEYASSFNGYMEGALRAAARAAQEVLDLL

Sequences:

>Translated_449_residues
MYDSIIIGAGLAGLTAAEELASAGHSVVVLEARARVGGRLENAELSNGQVVELGGQWVGEGHEELRSLLSSQGLELVDST
DGDVVVKARGRVSHVTSLSEPSAHSLSPFELADLGQGLLRFRRLADRVANNKGWAAANATWLNQSLSQWTVSNVRTEAGR
GYITNLFRQAFGVSANDTPLFNGLAKANAGVDLESLVAVNGGLKQQRVKGGVAQVTRNLAEPLGDDLKLSSPVRSVHSDD
DGVTVTTTDGTQYQGRSVIVTVPPRLLKDMTFEPALPAERLEMADKVPAGNVIKAYLVYDSPWWRTSGASGQMGADEGAV
RVIFDTSDDETGKGILMGFFEGTEASGYGKLSVGLRQRAFEEVVESAFGKAPSSPIEYLDRDWLSEPYTGGCHGAHFAPS
LWTTTGPILAEPLGRVFFAGAEYASSFNGYMEGALRAAARAAQEVLDLL
>Mature_449_residues
MYDSIIIGAGLAGLTAAEELASAGHSVVVLEARARVGGRLENAELSNGQVVELGGQWVGEGHEELRSLLSSQGLELVDST
DGDVVVKARGRVSHVTSLSEPSAHSLSPFELADLGQGLLRFRRLADRVANNKGWAAANATWLNQSLSQWTVSNVRTEAGR
GYITNLFRQAFGVSANDTPLFNGLAKANAGVDLESLVAVNGGLKQQRVKGGVAQVTRNLAEPLGDDLKLSSPVRSVHSDD
DGVTVTTTDGTQYQGRSVIVTVPPRLLKDMTFEPALPAERLEMADKVPAGNVIKAYLVYDSPWWRTSGASGQMGADEGAV
RVIFDTSDDETGKGILMGFFEGTEASGYGKLSVGLRQRAFEEVVESAFGKAPSSPIEYLDRDWLSEPYTGGCHGAHFAPS
LWTTTGPILAEPLGRVFFAGAEYASSFNGYMEGALRAAARAAQEVLDLL

Specific function: Unknown

COG id: COG1231

COG function: function code E; Monoamine oxidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin monoamine oxidase family [H]

Homologues:

Organism=Homo sapiens, GI4557735, Length=457, Percent_Identity=29.3216630196937, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI38202207, Length=444, Percent_Identity=28.3783783783784, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI23821023, Length=471, Percent_Identity=25.4777070063694, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI27477089, Length=473, Percent_Identity=25.7928118393235, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI116256451, Length=251, Percent_Identity=27.0916334661355, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI23097272, Length=491, Percent_Identity=24.6435845213849, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001613
- InterPro:   IPR002937 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 47714; Mature: 47714

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDSIIIGAGLAGLTAAEELASAGHSVVVLEARARVGGRLENAELSNGQVVELGGQWVGE
CCCCEEECCCCHHHHHHHHHHHCCCEEEEEEECHHHCCCCCCCCCCCCEEEEECCCCCCC
GHEELRSLLSSQGLELVDSTDGDVVVKARGRVSHVTSLSEPSAHSLSPFELADLGQGLLR
CHHHHHHHHHHCCCEEEECCCCCEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
FRRLADRVANNKGWAAANATWLNQSLSQWTVSNVRTEAGRGYITNLFRQAFGVSANDTPL
HHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHH
FNGLAKANAGVDLESLVAVNGGLKQQRVKGGVAQVTRNLAEPLGDDLKLSSPVRSVHSDD
HHHHHHCCCCCCHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCC
DGVTVTTTDGTQYQGRSVIVTVPPRLLKDMTFEPALPAERLEMADKVPAGNVIKAYLVYD
CCEEEEECCCCCCCCCEEEEECCHHHHHCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEEC
SPWWRTSGASGQMGADEGAVRVIFDTSDDETGKGILMGFFEGTEASGYGKLSVGLRQRAF
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHH
EEVVESAFGKAPSSPIEYLDRDWLSEPYTGGCHGAHFAPSLWTTTGPILAEPLGRVFFAG
HHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHCCC
AEYASSFNGYMEGALRAAARAAQEVLDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MYDSIIIGAGLAGLTAAEELASAGHSVVVLEARARVGGRLENAELSNGQVVELGGQWVGE
CCCCEEECCCCHHHHHHHHHHHCCCEEEEEEECHHHCCCCCCCCCCCCEEEEECCCCCCC
GHEELRSLLSSQGLELVDSTDGDVVVKARGRVSHVTSLSEPSAHSLSPFELADLGQGLLR
CHHHHHHHHHHCCCEEEECCCCCEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
FRRLADRVANNKGWAAANATWLNQSLSQWTVSNVRTEAGRGYITNLFRQAFGVSANDTPL
HHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHH
FNGLAKANAGVDLESLVAVNGGLKQQRVKGGVAQVTRNLAEPLGDDLKLSSPVRSVHSDD
HHHHHHCCCCCCHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCC
DGVTVTTTDGTQYQGRSVIVTVPPRLLKDMTFEPALPAERLEMADKVPAGNVIKAYLVYD
CCEEEEECCCCCCCCCEEEEECCHHHHHCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEEC
SPWWRTSGASGQMGADEGAVRVIFDTSDDETGKGILMGFFEGTEASGYGKLSVGLRQRAF
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHH
EEVVESAFGKAPSSPIEYLDRDWLSEPYTGGCHGAHFAPSLWTTTGPILAEPLGRVFFAG
HHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHCCC
AEYASSFNGYMEGALRAAARAAQEVLDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]