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The map label for this gene is ykoE [H]

Identifier: 50841644

GI number: 50841644

Start: 186661

End: 187290

Strand: Direct

Name: ykoE [H]

Synonym: PPA0156

Alternate gene names: 50841644

Gene position: 186661-187290 (Clockwise)

Preceding gene: 50841643

Following gene: 50841645

Centisome position: 7.29

GC content: 59.68

Gene sequence:

>630_bases
ATGACCAACGACAAACTCACCATGCGATACCGCACTATCGACATCGTGACTCCAGTGATGATTGTTGTGGCATTCGGCGT
CATCTTCCTCGGCTATGGAGCGGTATATAGTCTCCTCAAGCCGGCCACGTCGGTGTATCTGCCCATTGAGGGCATCCTTT
CTGGCATCTGGTTCCTGCCGGCACTTCTTGCTGGGCTCATCGTTCGTAAACCCGGTGCAGCCTTACTCTCCGAGGTTCTG
GCGGCCGCCATTGAGGCTGCTCTCGGCGGCCCGTGGGGGGCTGGCACCCTCATTTCCGGTGTTGTCCAGGCCCTGCCGAT
GGAGCTGTGTTTGCTCGTCGTCGCCTACCGCAAGGCCGGTCCGAAGCTTGTCCTGGTGGCCGGGGCTCTTACCGGTTTCG
CTGAGGCCATCTACGAGCGCATCTCTTACTACCCGATGTTCCGTTTCGGCGACACGATCGTCTACTTCGTTTTCATGATC
GTTTCCGGGGCTCTGCTCGGCGGTCTGGTGGCATGGGGTATTGTCCGTGGCCTCGCGGCTGCCGGTGCGCTCAGCCCCTT
CGCAGTTTCTCGTGAATTGCGTGGCGGGAAGTCACCCCGGAGCACAATCTCATCGCGAAACCTGTCATGA

Upstream 100 bases:

>100_bases
GGCACCGCCCAGACCCTCGAACCTGAACCGGTTAGGACCGGCGTAGGGAGTCGGGCTCTTCGCGCTTTCGCGCCCCTTCC
GAATGAGCGGAAGGACTTCT

Downstream 100 bases:

>100_bases
CTGACGTCTTGACCCATGCTGACCACGTTGACGAGGTTTCCAGCCGCCGGGCGGTGCCGGTGGATGTCGAGGGGATGACG
GTCGGCGTTCCCGATCGCGA

Product: putative ABC-type transporter, permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTNDKLTMRYRTIDIVTPVMIVVAFGVIFLGYGAVYSLLKPATSVYLPIEGILSGIWFLPALLAGLIVRKPGAALLSEVL
AAAIEAALGGPWGAGTLISGVVQALPMELCLLVVAYRKAGPKLVLVAGALTGFAEAIYERISYYPMFRFGDTIVYFVFMI
VSGALLGGLVAWGIVRGLAAAGALSPFAVSRELRGGKSPRSTISSRNLS

Sequences:

>Translated_209_residues
MTNDKLTMRYRTIDIVTPVMIVVAFGVIFLGYGAVYSLLKPATSVYLPIEGILSGIWFLPALLAGLIVRKPGAALLSEVL
AAAIEAALGGPWGAGTLISGVVQALPMELCLLVVAYRKAGPKLVLVAGALTGFAEAIYERISYYPMFRFGDTIVYFVFMI
VSGALLGGLVAWGIVRGLAAAGALSPFAVSRELRGGKSPRSTISSRNLS
>Mature_208_residues
TNDKLTMRYRTIDIVTPVMIVVAFGVIFLGYGAVYSLLKPATSVYLPIEGILSGIWFLPALLAGLIVRKPGAALLSEVLA
AAIEAALGGPWGAGTLISGVVQALPMELCLLVVAYRKAGPKLVLVAGALTGFAEAIYERISYYPMFRFGDTIVYFVFMIV
SGALLGGLVAWGIVRGLAAAGALSPFAVSRELRGGKSPRSTISSRNLS

Specific function: Part of the ABC transporter complex ykoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable)

COG id: COG4721

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017195 [H]

Pfam domain/function: PF09819 ABC_cobalt [H]

EC number: NA

Molecular weight: Translated: 22013; Mature: 21881

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDKLTMRYRTIDIVTPVMIVVAFGVIFLGYGAVYSLLKPATSVYLPIEGILSGIWFLP
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHH
ALLAGLIVRKPGAALLSEVLAAAIEAALGGPWGAGTLISGVVQALPMELCLLVVAYRKAG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PKLVLVAGALTGFAEAIYERISYYPMFRFGDTIVYFVFMIVSGALLGGLVAWGIVRGLAA
CEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGALSPFAVSRELRGGKSPRSTISSRNLS
HCCCCHHHHHHHHCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
TNDKLTMRYRTIDIVTPVMIVVAFGVIFLGYGAVYSLLKPATSVYLPIEGILSGIWFLP
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHH
ALLAGLIVRKPGAALLSEVLAAAIEAALGGPWGAGTLISGVVQALPMELCLLVVAYRKAG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PKLVLVAGALTGFAEAIYERISYYPMFRFGDTIVYFVFMIVSGALLGGLVAWGIVRGLAA
CEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGALSPFAVSRELRGGKSPRSTISSRNLS
HCCCCHHHHHHHHCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]