Click here to switch to the map view.

The map label for this gene is lacF [H]

Identifier: 50841548

GI number: 50841548

Start: 56867

End: 57763

Strand: Reverse

Name: lacF [H]

Synonym: PPA0058

Alternate gene names: 50841548

Gene position: 57763-56867 (Counterclockwise)

Preceding gene: 50841549

Following gene: 50841547

Centisome position: 2.26

GC content: 54.96

Gene sequence:

>897_bases
ATGCGCAAGGCTTTGCCGATCTATGCCGCTTTGAGTCCGTATTTCTTCTTTTTCCTTGTCTTCGCCGCTATACCGATGAT
CTTTACCCTGCTACTAGCCTTCACTGACTGGTCAGGCTTGGGGAGTGCCCATTTCGTCGGTTTAGAGAATTTCACCTATC
TCATCAGCGACCACCTGTTCTACAAGTCGCTGGGCAACACGCTTATTCTGTGGGCGATGGGCACGATCCCGACACTCATC
ATTGCCACGATCGTCGCCCTCATGCTGAACAAGACGATGCGGTTCTCTACGACCTATCGGGTCATTTACTTGGTCCCGAA
TATCACGTCCATGGTGGCTATGGGAATCTTGTTCAGCTCGATTTTCTCCAGCCAGTTCGGCCTGGCCAACGCCGTGCGCA
ACTTGCTAGGTCAGGAAAATATCGCCTGGTTGCAAAACGAGTGGGGCATCAAGATCGCCATCTCGTCCCTGACAGTGTGG
TCATTCGTCGGCTATAACGCACTGCTCATCCTCGCCGGTCTGCAAGCCATCGACAAGACGCAGTATGAGGCGGCTGCCAT
TGACGGGGCCAACGGGTGGCAGACGTTCTTCCATGTCACCTTGCCCCAACTTCGTGCCATCGTCTTGTTCATCACCCTCA
TGTCGACGATCGGTTCGTTGCAGAGCTTCACCGAGGCGCAGGTGCTCACGAGTTCTCAGTCCGCCGGGGCGGCCTCGGCA
GGCGGGGTGAACAATTCCGGTTTGACGATGGTGCTCTACTTCTACTCAGTGGCCTTTCAGGAGAACCGATACGGCTATGG
AGCGACGATCGCCTGGGGAGTATTCGTCGTTGTGCTGTTCTTCTCGATCATTAACTGGCTCGTTACCCGCGAGCATGATC
GCAAGGTGGCACGATGA

Upstream 100 bases:

>100_bases
TCTCACCGTCAGGTGAGGCGTCTGTACCGAGATGAGTTCACCACATACCGTCACCGCCACGCCCACGGACGAGCTGCATC
ACCCGTCCGTGGGTCGGCGA

Downstream 100 bases:

>100_bases
GACGGCGGGTGCACATCGGGGCGTTCTTCCGACACCTGTTCCTCATTCTGGGCGGGCTGATCTCGCTATTCCCGTTCTAC
TGGATGTTCGTGCTAGCCAG

Product: transport permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MRKALPIYAALSPYFFFFLVFAAIPMIFTLLLAFTDWSGLGSAHFVGLENFTYLISDHLFYKSLGNTLILWAMGTIPTLI
IATIVALMLNKTMRFSTTYRVIYLVPNITSMVAMGILFSSIFSSQFGLANAVRNLLGQENIAWLQNEWGIKIAISSLTVW
SFVGYNALLILAGLQAIDKTQYEAAAIDGANGWQTFFHVTLPQLRAIVLFITLMSTIGSLQSFTEAQVLTSSQSAGAASA
GGVNNSGLTMVLYFYSVAFQENRYGYGATIAWGVFVVVLFFSIINWLVTREHDRKVAR

Sequences:

>Translated_298_residues
MRKALPIYAALSPYFFFFLVFAAIPMIFTLLLAFTDWSGLGSAHFVGLENFTYLISDHLFYKSLGNTLILWAMGTIPTLI
IATIVALMLNKTMRFSTTYRVIYLVPNITSMVAMGILFSSIFSSQFGLANAVRNLLGQENIAWLQNEWGIKIAISSLTVW
SFVGYNALLILAGLQAIDKTQYEAAAIDGANGWQTFFHVTLPQLRAIVLFITLMSTIGSLQSFTEAQVLTSSQSAGAASA
GGVNNSGLTMVLYFYSVAFQENRYGYGATIAWGVFVVVLFFSIINWLVTREHDRKVAR
>Mature_298_residues
MRKALPIYAALSPYFFFFLVFAAIPMIFTLLLAFTDWSGLGSAHFVGLENFTYLISDHLFYKSLGNTLILWAMGTIPTLI
IATIVALMLNKTMRFSTTYRVIYLVPNITSMVAMGILFSSIFSSQFGLANAVRNLLGQENIAWLQNEWGIKIAISSLTVW
SFVGYNALLILAGLQAIDKTQYEAAAIDGANGWQTFFHVTLPQLRAIVLFITLMSTIGSLQSFTEAQVLTSSQSAGAASA
GGVNNSGLTMVLYFYSVAFQENRYGYGATIAWGVFVVVLFFSIINWLVTREHDRKVAR

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787570, Length=254, Percent_Identity=26.7716535433071, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790465, Length=255, Percent_Identity=26.2745098039216, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789861, Length=201, Percent_Identity=26.865671641791, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32969; Mature: 32969

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKALPIYAALSPYFFFFLVFAAIPMIFTLLLAFTDWSGLGSAHFVGLENFTYLISDHLF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHH
YKSLGNTLILWAMGTIPTLIIATIVALMLNKTMRFSTTYRVIYLVPNITSMVAMGILFSS
HHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHEEEEEEEEEEECCCHHHHHHHHHHHHH
IFSSQFGLANAVRNLLGQENIAWLQNEWGIKIAISSLTVWSFVGYNALLILAGLQAIDKT
HHHHCCCHHHHHHHHHCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
QYEAAAIDGANGWQTFFHVTLPQLRAIVLFITLMSTIGSLQSFTEAQVLTSSQSAGAASA
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GGVNNSGLTMVLYFYSVAFQENRYGYGATIAWGVFVVVLFFSIINWLVTREHDRKVAR
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCC
>Mature Secondary Structure
MRKALPIYAALSPYFFFFLVFAAIPMIFTLLLAFTDWSGLGSAHFVGLENFTYLISDHLF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHH
YKSLGNTLILWAMGTIPTLIIATIVALMLNKTMRFSTTYRVIYLVPNITSMVAMGILFSS
HHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHEEEEEEEEEEECCCHHHHHHHHHHHHH
IFSSQFGLANAVRNLLGQENIAWLQNEWGIKIAISSLTVWSFVGYNALLILAGLQAIDKT
HHHHCCCHHHHHHHHHCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
QYEAAAIDGANGWQTFFHVTLPQLRAIVLFITLMSTIGSLQSFTEAQVLTSSQSAGAASA
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GGVNNSGLTMVLYFYSVAFQENRYGYGATIAWGVFVVVLFFSIINWLVTREHDRKVAR
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]