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The map label for this gene is gatC [H]

Identifier: 50841516

GI number: 50841516

Start: 23734

End: 24990

Strand: Reverse

Name: gatC [H]

Synonym: PPA0022

Alternate gene names: 50841516

Gene position: 24990-23734 (Counterclockwise)

Preceding gene: 50841517

Following gene: 50841515

Centisome position: 0.98

GC content: 54.18

Gene sequence:

>1257_bases
ATGTCAATTATCAAAGGCATTCTTGACGTCGGCGCCGTGGTTATCCTGCCGATCGTGATGCTGATTCTTTGCCTGATCTT
CAGGATACCTTTCGGTAAGTCCCTCAAGGCCGGTCTGATGATCGGTATCGGATTCTCCGGGCTTTCCCTCGTCATCGGAT
TCCTGATGACGTCTGTGCAGTCGGCAGTGGATTACTACCGGCACATGGGCGGAGGATTCACGACTGTTGATGTCGGCTGG
GCAGCAGTCGGCGCGGCTTCATTCGGAGTACCCTTTGCCGCTCCTGCCATCCTCCTTGTCGTCCTCATAAATGTTGTCAT
GATCCTCGCGAAAATGACGAACGTACTCAACGTCGACATCTGGAACTTCATCCATTTCTTGGTCCCAGGAACGCTGGCCT
ATGCACTAACGAACAACGCATGGATCGGATTAGGTGTCGTCTTGGTGCTTTCGGTCATTGACCTCATCGTCGCTCAGCAT
ATCGCACCAAAATGGCAAGAATACTACGGCCTCACAGGGACAACATGTTCGACTCTTTCCTACATCACGTCAGCATGGCC
CATTGCGATCGGATTGAACTGGGTCATCGACAAAATCCCCGGAGTTCGTAAGATCGACATCTCCATGGAGAAATTCGGCG
ACAGGCTCGGATTCTTCGGCGACACCGCCTTCATCGGCCTCATCGTTGGTATCTTCCTGGGACTCATGACCCGTCAACCT
TGGCAGGGTGTCCTCGTCATGGGTATGGGAATCGCCACCGTTCTGGTACTCCTACCTCGAATGGTCTCGGTCATGATGGA
GGGCCTGTCGACGGTCGGTGAAGGTGCGAAGACCTTCATGAAGCGTCACCTCGGAAAGAACAAGGACGGCAGCGAACGCG
AGCTCAGCATCGGCATGGATGTCGCTCTGGCACTCGGTGACCCGGCGGCCATCACCATCACCGTTCTCATGATCCCGCTG
TGCATTGCCTTCGCATTCATTATCCCCGGAATGAACTACTTCCCAGTCGGCATGCTTACCGTGATCGTCTACATGATGCC
GATGATCTGCCTGGCTTGTAACGGAAACATGTTTCGCTCTCTCATCATTGGGGCGATCTACATGTTCTTCGTCGAGTGGG
GTGCCAGCTTCTTCGCACCGGAGGCTACTGCGATGATGCATGCCACCGGCGTTCATGTCTCCGGGTCTGTGACTGATGCG
TTCTTCGGGTACAACCTTCCCAACATCATCATCTCGGCGATCCATCGGATGTTCTGA

Upstream 100 bases:

>100_bases
GTCTCATTTCGGGCATCAACGAAGACGCGGTGGCAGAAGAAATCATCTCCACGTGTCGAGATATCTTGAACCAGTCATGA
TATTCTAGGAACACTCAATA

Downstream 100 bases:

>100_bases
TCCGGAACAGCGCAGTATTTTATGGCCATTTCTGATCCCGTGAAAGCAGTAACAACATGAGCGTACTTCTGAACACCGAT
CTGATAAGTGTGAATATCGA

Product: PTS system, galactitol-specific IIC component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSIIKGILDVGAVVILPIVMLILCLIFRIPFGKSLKAGLMIGIGFSGLSLVIGFLMTSVQSAVDYYRHMGGGFTTVDVGW
AAVGAASFGVPFAAPAILLVVLINVVMILAKMTNVLNVDIWNFIHFLVPGTLAYALTNNAWIGLGVVLVLSVIDLIVAQH
IAPKWQEYYGLTGTTCSTLSYITSAWPIAIGLNWVIDKIPGVRKIDISMEKFGDRLGFFGDTAFIGLIVGIFLGLMTRQP
WQGVLVMGMGIATVLVLLPRMVSVMMEGLSTVGEGAKTFMKRHLGKNKDGSERELSIGMDVALALGDPAAITITVLMIPL
CIAFAFIIPGMNYFPVGMLTVIVYMMPMICLACNGNMFRSLIIGAIYMFFVEWGASFFAPEATAMMHATGVHVSGSVTDA
FFGYNLPNIIISAIHRMF

Sequences:

>Translated_418_residues
MSIIKGILDVGAVVILPIVMLILCLIFRIPFGKSLKAGLMIGIGFSGLSLVIGFLMTSVQSAVDYYRHMGGGFTTVDVGW
AAVGAASFGVPFAAPAILLVVLINVVMILAKMTNVLNVDIWNFIHFLVPGTLAYALTNNAWIGLGVVLVLSVIDLIVAQH
IAPKWQEYYGLTGTTCSTLSYITSAWPIAIGLNWVIDKIPGVRKIDISMEKFGDRLGFFGDTAFIGLIVGIFLGLMTRQP
WQGVLVMGMGIATVLVLLPRMVSVMMEGLSTVGEGAKTFMKRHLGKNKDGSERELSIGMDVALALGDPAAITITVLMIPL
CIAFAFIIPGMNYFPVGMLTVIVYMMPMICLACNGNMFRSLIIGAIYMFFVEWGASFFAPEATAMMHATGVHVSGSVTDA
FFGYNLPNIIISAIHRMF
>Mature_417_residues
SIIKGILDVGAVVILPIVMLILCLIFRIPFGKSLKAGLMIGIGFSGLSLVIGFLMTSVQSAVDYYRHMGGGFTTVDVGWA
AVGAASFGVPFAAPAILLVVLINVVMILAKMTNVLNVDIWNFIHFLVPGTLAYALTNNAWIGLGVVLVLSVIDLIVAQHI
APKWQEYYGLTGTTCSTLSYITSAWPIAIGLNWVIDKIPGVRKIDISMEKFGDRLGFFGDTAFIGLIVGIFLGLMTRQPW
QGVLVMGMGIATVLVLLPRMVSVMMEGLSTVGEGAKTFMKRHLGKNKDGSERELSIGMDVALALGDPAAITITVLMIPLC
IAFAFIIPGMNYFPVGMLTVIVYMMPMICLACNGNMFRSLIIGAIYMFFVEWGASFFAPEATAMMHATGVHVSGSVTDAF
FGYNLPNIIISAIHRMF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=381, Percent_Identity=33.3333333333333, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1790758, Length=391, Percent_Identity=30.690537084399, Blast_Score=184, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: 2.7.1.69

Molecular weight: Translated: 45029; Mature: 44898

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIIKGILDVGAVVILPIVMLILCLIFRIPFGKSLKAGLMIGIGFSGLSLVIGFLMTSVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHH
SAVDYYRHMGGGFTTVDVGWAAVGAASFGVPFAAPAILLVVLINVVMILAKMTNVLNVDI
HHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WNFIHFLVPGTLAYALTNNAWIGLGVVLVLSVIDLIVAQHIAPKWQEYYGLTGTTCSTLS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHH
YITSAWPIAIGLNWVIDKIPGVRKIDISMEKFGDRLGFFGDTAFIGLIVGIFLGLMTRQP
HHHHCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
WQGVLVMGMGIATVLVLLPRMVSVMMEGLSTVGEGAKTFMKRHLGKNKDGSERELSIGMD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCE
VALALGDPAAITITVLMIPLCIAFAFIIPGMNYFPVGMLTVIVYMMPMICLACNGNMFRS
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
LIIGAIYMFFVEWGASFFAPEATAMMHATGVHVSGSVTDAFFGYNLPNIIISAIHRMF
HHHHHHHHHHHHHCHHHCCCCHHHHHHHCCCEECCCHHHHHHCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SIIKGILDVGAVVILPIVMLILCLIFRIPFGKSLKAGLMIGIGFSGLSLVIGFLMTSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHH
SAVDYYRHMGGGFTTVDVGWAAVGAASFGVPFAAPAILLVVLINVVMILAKMTNVLNVDI
HHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WNFIHFLVPGTLAYALTNNAWIGLGVVLVLSVIDLIVAQHIAPKWQEYYGLTGTTCSTLS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHH
YITSAWPIAIGLNWVIDKIPGVRKIDISMEKFGDRLGFFGDTAFIGLIVGIFLGLMTRQP
HHHHCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
WQGVLVMGMGIATVLVLLPRMVSVMMEGLSTVGEGAKTFMKRHLGKNKDGSERELSIGMD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCE
VALALGDPAAITITVLMIPLCIAFAFIIPGMNYFPVGMLTVIVYMMPMICLACNGNMFRS
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
LIIGAIYMFFVEWGASFFAPEATAMMHATGVHVSGSVTDAFFGYNLPNIIISAIHRMF
HHHHHHHHHHHHHCHHHCCCCHHHHHHHCCCEECCCHHHHHHCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]