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The map label for this gene is dnaA

Identifier: 50841497

GI number: 50841497

Start: 245

End: 1747

Strand: Direct

Name: dnaA

Synonym: PPA0001

Alternate gene names: 50841497

Gene position: 245-1747 (Clockwise)

Preceding gene: NA

Following gene: 161621802

Centisome position: 0.01

GC content: 56.95

Gene sequence:

>1503_bases
ATGTCCGACACACCGTTCGGCGACGCCGACCACCCTCGTCCCGCGCCGATCCATCCGGATGCTGTATTGCCCCCGCCGAT
GAGTTCACAGTCGGCTGATAATGATCCCACTGAGGCCCTCAATGAAGCTTGGACCAACATCCTTACGAAGGTTTCGAAAC
CTAATCGCGCGTGGTTATCCAACACTACCCCGGTGACGATGCACTCTTCTACGGCGATGGTTGCCGTTCCCAACGAATTT
GCCCGTGACCGTCTTGAATCAAAGATGCGTTACGAACTAGAAGAACTCCTCTCTGACCATTTTCACAAAGCCATCCACCT
AGCCATCACCATCGATCCCGATCTGGAATTGGCTCTTGGTGCTCCTGACCATGAGGACGAGGAAGAAGAGGTTCCACCTG
CCCAGTTCGTCCCCAAGGTCACCGTCGGAGTCACTGAACCCTCTGCTCGGCCCACCACCACTATCGACGATGACGAAGGC
AACCGACTCAACCCGAAGTACACCTTCGATTCCTTCGTCATCGGTGCATCTAATCGGTTTGCTCACGCCGCCGCAGTCGC
GGTTGCCGAGGCCCCTGGAAAGTCGTACAACCCGCTGCTTATCTATGGCGGCTCTGGGCTAGGGAAAACCCACCTGCTGC
ATGCCATCGGGCGTTACGTCATGTCGTATTACGACAACGTCAAAGTGAAGTACGTCTCTACCGAGGAACTCACCAACGAC
TTCATCAACGCCATCGGCACCAACCGCACCACGGAGTTCCGTCGCTCTTACCGCGATGTTGACGTCCTGCTAGTTGACGA
CATCCAGTTTTTGCAGTCGAAGATCCAAACCCAGGAAGAGTTCTTCCACACCTTCAATACTCTTCACAACGCCCAGAAGC
AGATCGTCATGACCTCTGACCGGCCGCCTAAGCTGTTGGAGGCCCTTGAGCCGCGTCTGCGCAGCCGGTTTGAATGGGGT
CTGCTTACTGACATCCAGCCTCCAGATCTAGAGACTCGCATCGCCATCCTGCGGCGCAAGGTTGCGGCCGAGAAGATCAC
CGTCGAGCCGGACGTGCTGGAGTTCATCGCTAGCCGTATCCAAACCAATATCCGTGAGCTCGAGGGAGCCCTCATCCGGG
TGACGGCTTTTGCCAGCCTCAATCAGCAACCGGTGGATATCTCTCTGGCTGAAGTCGTCCTCAAGGACCTCATCCCGGAA
GGTCGCGAGACCCCGGTGACACCAGAGCGCATTATCGCGGAGACCGCCGACTACTTCGACATCTCTGCGGACGATCTTTT
AGGCACCTCCCGCGCTCAGACCCTTGTCACAGCCCGACAAATTGCGATGTACCTGTGCCGCGAGCTCACTGACCTCTCGT
TGCCCAAGATCGGCGCCGAGTTTGGCGGCAAGGACCACACCACCGTCATGCATGCTGACCGCAAGATTCGCGCCCTCATG
GGGGAGCAGCGTCAGATCTTCAATCAGGTCTCTGAGATCACCAACCGCATCAAGCAGTACTGA

Upstream 100 bases:

>100_bases
CTAGCGTTCAGGGGAGTGGTACATCGTGGGTAGCTTGTCACACCGACTGTGGAAAACTGTGTGGACAACTCTCGACAACT
TCTAGAGAACAGGTGGTGGA

Downstream 100 bases:

>100_bases
GCTGAACCGCAGCCTACGGTGACAGCTATACCTGTGTCGTTGAGCTAGGCACAAGCCCGCCCCGTGACACCTATCCCCAC
ACCCATATGTGGAAAACCAG

Product: chromosomal replication initiator protein DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MSDTPFGDADHPRPAPIHPDAVLPPPMSSQSADNDPTEALNEAWTNILTKVSKPNRAWLSNTTPVTMHSSTAMVAVPNEF
ARDRLESKMRYELEELLSDHFHKAIHLAITIDPDLELALGAPDHEDEEEEVPPAQFVPKVTVGVTEPSARPTTTIDDDEG
NRLNPKYTFDSFVIGASNRFAHAAAVAVAEAPGKSYNPLLIYGGSGLGKTHLLHAIGRYVMSYYDNVKVKYVSTEELTND
FINAIGTNRTTEFRRSYRDVDVLLVDDIQFLQSKIQTQEEFFHTFNTLHNAQKQIVMTSDRPPKLLEALEPRLRSRFEWG
LLTDIQPPDLETRIAILRRKVAAEKITVEPDVLEFIASRIQTNIRELEGALIRVTAFASLNQQPVDISLAEVVLKDLIPE
GRETPVTPERIIAETADYFDISADDLLGTSRAQTLVTARQIAMYLCRELTDLSLPKIGAEFGGKDHTTVMHADRKIRALM
GEQRQIFNQVSEITNRIKQY

Sequences:

>Translated_500_residues
MSDTPFGDADHPRPAPIHPDAVLPPPMSSQSADNDPTEALNEAWTNILTKVSKPNRAWLSNTTPVTMHSSTAMVAVPNEF
ARDRLESKMRYELEELLSDHFHKAIHLAITIDPDLELALGAPDHEDEEEEVPPAQFVPKVTVGVTEPSARPTTTIDDDEG
NRLNPKYTFDSFVIGASNRFAHAAAVAVAEAPGKSYNPLLIYGGSGLGKTHLLHAIGRYVMSYYDNVKVKYVSTEELTND
FINAIGTNRTTEFRRSYRDVDVLLVDDIQFLQSKIQTQEEFFHTFNTLHNAQKQIVMTSDRPPKLLEALEPRLRSRFEWG
LLTDIQPPDLETRIAILRRKVAAEKITVEPDVLEFIASRIQTNIRELEGALIRVTAFASLNQQPVDISLAEVVLKDLIPE
GRETPVTPERIIAETADYFDISADDLLGTSRAQTLVTARQIAMYLCRELTDLSLPKIGAEFGGKDHTTVMHADRKIRALM
GEQRQIFNQVSEITNRIKQY
>Mature_499_residues
SDTPFGDADHPRPAPIHPDAVLPPPMSSQSADNDPTEALNEAWTNILTKVSKPNRAWLSNTTPVTMHSSTAMVAVPNEFA
RDRLESKMRYELEELLSDHFHKAIHLAITIDPDLELALGAPDHEDEEEEVPPAQFVPKVTVGVTEPSARPTTTIDDDEGN
RLNPKYTFDSFVIGASNRFAHAAAVAVAEAPGKSYNPLLIYGGSGLGKTHLLHAIGRYVMSYYDNVKVKYVSTEELTNDF
INAIGTNRTTEFRRSYRDVDVLLVDDIQFLQSKIQTQEEFFHTFNTLHNAQKQIVMTSDRPPKLLEALEPRLRSRFEWGL
LTDIQPPDLETRIAILRRKVAAEKITVEPDVLEFIASRIQTNIRELEGALIRVTAFASLNQQPVDISLAEVVLKDLIPEG
RETPVTPERIIAETADYFDISADDLLGTSRAQTLVTARQIAMYLCRELTDLSLPKIGAEFGGKDHTTVMHADRKIRALMG
EQRQIFNQVSEITNRIKQY

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=331, Percent_Identity=48.6404833836858, Blast_Score=319, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA_PROAC (Q6ABL5)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_054724.1
- ProteinModelPortal:   Q6ABL5
- SMR:   Q6ABL5
- GeneID:   2931966
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA0001
- NMPDR:   fig|267747.1.peg.1
- HOGENOM:   HBG695666
- OMA:   DEVAFLI
- ProtClustDB:   CLSK2763007
- BioCyc:   PACN267747:PPA0001-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760
- TIGRFAMs:   TIGR00362

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 56019; Mature: 55888

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTPFGDADHPRPAPIHPDAVLPPPMSSQSADNDPTEALNEAWTNILTKVSKPNRAWLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
NTTPVTMHSSTAMVAVPNEFARDRLESKMRYELEELLSDHFHKAIHLAITIDPDLELALG
CCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCEEEEC
APDHEDEEEEVPPAQFVPKVTVGVTEPSARPTTTIDDDEGNRLNPKYTFDSFVIGASNRF
CCCCCCCHHCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCEEEECCCCH
AHAAAVAVAEAPGKSYNPLLIYGGSGLGKTHLLHAIGRYVMSYYDNVKVKYVSTEELTND
HHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHH
FINAIGTNRTTEFRRSYRDVDVLLVDDIQFLQSKIQTQEEFFHTFNTLHNAQKQIVMTSD
HHHHHCCCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
RPPKLLEALEPRLRSRFEWGLLTDIQPPDLETRIAILRRKVAAEKITVEPDVLEFIASRI
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QTNIRELEGALIRVTAFASLNQQPVDISLAEVVLKDLIPEGRETPVTPERIIAETADYFD
HHHHHHHCCCEEEEEEHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCC
ISADDLLGTSRAQTLVTARQIAMYLCRELTDLSLPKIGAEFGGKDHTTVMHADRKIRALM
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEECHHHHHHHH
GEQRQIFNQVSEITNRIKQY
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDTPFGDADHPRPAPIHPDAVLPPPMSSQSADNDPTEALNEAWTNILTKVSKPNRAWLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
NTTPVTMHSSTAMVAVPNEFARDRLESKMRYELEELLSDHFHKAIHLAITIDPDLELALG
CCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCEEEEC
APDHEDEEEEVPPAQFVPKVTVGVTEPSARPTTTIDDDEGNRLNPKYTFDSFVIGASNRF
CCCCCCCHHCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCEEEECCCCH
AHAAAVAVAEAPGKSYNPLLIYGGSGLGKTHLLHAIGRYVMSYYDNVKVKYVSTEELTND
HHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHH
FINAIGTNRTTEFRRSYRDVDVLLVDDIQFLQSKIQTQEEFFHTFNTLHNAQKQIVMTSD
HHHHHCCCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
RPPKLLEALEPRLRSRFEWGLLTDIQPPDLETRIAILRRKVAAEKITVEPDVLEFIASRI
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QTNIRELEGALIRVTAFASLNQQPVDISLAEVVLKDLIPEGRETPVTPERIIAETADYFD
HHHHHHHCCCEEEEEEHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCC
ISADDLLGTSRAQTLVTARQIAMYLCRELTDLSLPKIGAEFGGKDHTTVMHADRKIRALM
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEECHHHHHHHH
GEQRQIFNQVSEITNRIKQY
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA