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The map label for this gene is rnpA

Identifier: 50365497

GI number: 50365497

Start: 792445

End: 792777

Strand: Reverse

Name: rnpA

Synonym: Mfl682

Alternate gene names: 50365497

Gene position: 792777-792445 (Counterclockwise)

Preceding gene: 50365498

Following gene: 50365496

Centisome position: 99.94

GC content: 21.92

Gene sequence:

>333_bases
ATGAAAAATAAAAAAATTATAAAAAAGAATTTTGAATTTCAAGAAATAATAAGTAAGCAAGAATTTCATAGAAATTCTGC
ATTTGTAATTTATTATTCTAAAAACGATAAAGGATATTTTAGATACGGTATAAGTGTTGGTAAAAAATTAGGCAACGCAG
TTACTAGAAATAAAATTAAAAGACAAATTAGAATGATGATTCAAGATCAAATAAAGATATTGCCTGAATTCTCATACGAT
ATTGTAATTATTGCAAGAAACAGAATGATGCAAAATTCATTTGATCAAAATCAAAAAGAATTAAACAAATTAGTTGTTAG
ATTTTTAAAATAG

Upstream 100 bases:

>100_bases
CGGTTTTAGAGCTAGAATGGCTACTAAAAATGGAAGAAAAGTTATCAAAGCTCGTAGAGCAAAAGGTAGAGCTAAATTAA
CTGCTTAATTTTTTTGTGAA

Downstream 100 bases:

>100_bases
CAAGGAGGTGCTAATTTTGTATAATGAAAATCAATTATTTATGTCTAACCCAAAGAAAAATGGGGTTATGTCATACATGA
ACTCAAATAGCACCACAAAA

Product: ribonuclease P protein component

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MKNKKIIKKNFEFQEIISKQEFHRNSAFVIYYSKNDKGYFRYGISVGKKLGNAVTRNKIKRQIRMMIQDQIKILPEFSYD
IVIIARNRMMQNSFDQNQKELNKLVVRFLK

Sequences:

>Translated_110_residues
MKNKKIIKKNFEFQEIISKQEFHRNSAFVIYYSKNDKGYFRYGISVGKKLGNAVTRNKIKRQIRMMIQDQIKILPEFSYD
IVIIARNRMMQNSFDQNQKELNKLVVRFLK
>Mature_110_residues
MKNKKIIKKNFEFQEIISKQEFHRNSAFVIYYSKNDKGYFRYGISVGKKLGNAVTRNKIKRQIRMMIQDQIKILPEFSYD
IVIIARNRMMQNSFDQNQKELNKLVVRFLK

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_MESFL (Q6F0D5)

Other databases:

- EMBL:   AE017263
- RefSeq:   YP_053922.1
- ProteinModelPortal:   Q6F0D5
- SMR:   Q6F0D5
- GeneID:   2897775
- GenomeReviews:   AE017263_GR
- KEGG:   mfl:Mfl682
- HOGENOM:   HBG728160
- OMA:   SIPKKFA
- ProtClustDB:   CLSK745935
- BioCyc:   MFLO265311:MFL682-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13284; Mature: 13284

Theoretical pI: Translated: 10.95; Mature: 10.95

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKKIIKKNFEFQEIISKQEFHRNSAFVIYYSKNDKGYFRYGISVGKKLGNAVTRNKIK
CCCCCHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHH
RQIRMMIQDQIKILPEFSYDIVIIARNRMMQNSFDQNQKELNKLVVRFLK
HHHHHHHHHHHHHCCCCCCCEEEEECCHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKKIIKKNFEFQEIISKQEFHRNSAFVIYYSKNDKGYFRYGISVGKKLGNAVTRNKIK
CCCCCHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHH
RQIRMMIQDQIKILPEFSYDIVIIARNRMMQNSFDQNQKELNKLVVRFLK
HHHHHHHHHHHHHCCCCCCCEEEEECCHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA