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The map label for this gene is ygbD [C]

Identifier: 50365468

GI number: 50365468

Start: 759489

End: 760817

Strand: Reverse

Name: ygbD [C]

Synonym: Mfl653

Alternate gene names: 50365468

Gene position: 760817-759489 (Counterclockwise)

Preceding gene: 50365470

Following gene: 50365467

Centisome position: 95.91

GC content: 26.71

Gene sequence:

>1329_bases
ATGAAAACTGTTATTATTGGTGGTTCAGCAACGGGTATGGGTGTTGCAGCTAAACTTAAAAGACTAAATGAACAAAATGA
AATAGTTGTTATTCAGGATAAGGATTATGTTTCGCTTGGAGCTTGCGGAATACCATATTATATAGGTCATAATTTTGAAA
ATCCAGAAACCTTGATCGCAAGAAAAATTGAAAAATTTGAAGAATCACAGATTTCTGTTATTAGTAATTCAAAAGTAAAC
AAAATCGATTTTGAAAATAAAAAGGTTATTTTTGAAGAATCACAGATATCTTATGACAATTTAGTTATTGCTGTTGGTGC
AAAACCAATAACTCCTGAAATTAAAAATATAGATGCCAAAAATATATTTACTGTTAATTCAAAAGAAGACGCGATTGAAA
TTAGAAAAACAATCAATGATGATAGTAACGTTTTAATAATAGGATCAGGTTTAATTGGTTTAGAAATGGTTGAAAATATT
AAACATAGTACAGCAGCAAAAATATCAATTATTGAAAAAGCAGATAGAGTGTTAAAAAATTTATTTGATGAAGAATTTTC
TGAATTAGTAGAAAAAGAAATTTTAAATCAAGAAATAGAGCTGTTTAAAAATAATGAAGTTATAGAATTTGTTAAAGATA
ATAATGGCAAAGTAACTGGAGCTAAAACAATTAATGGTGAAATAATAAAATGTGATGTGGTTATTTTAAGTATTGGTGTT
ATACCAAATACTTCATTTCTAAGAGATACCGATTTAGAGTTAGAAAATAATGGTGCAATAAAAATTAACGAATATTGTGA
AACGAATATTCCTAATGTTTACGCAGGTGGAGATTGTTGTAGCAGTTTAAGTTATTTATATAAAAACACAAGAACATTTT
ATTTAGCAACAGTGGCAAATAAACAGGCAAAAATAATAGCAAATAATGTTAATAAAAATAAATCAAGTAAATTTGTTGGG
GCATTAGGAACAACAATAATAAGATTCTTTGATTTAGAGTTAGCGAGAACTGGTGAAAATAGAATGTTTATTGATATGAA
CAGTATTGAAACTAAAGAAGTTTTAATTAAAGATAAGGATCACACTAATTATGTAACTGGGCAAGAAGATATATGATTGA
AAGTAATCATAGATGTTAAAACTAAAGAAATTATTAACGTGCAAATGATAGGAAAAAATAAATCTGTTTTAAGAATTTAT
GGATTAGTTGGTTTAATTTGGTCAAGAAGTAAAGTTGACGAAACTTTAGAGCAAATTGATTTGCCATACTCTCCACCGTT
TTCAAGAACAACAGATATTATTCATATTGCTTTAAGTAAGTTAATATAA

Upstream 100 bases:

>100_bases
GCTTATATATATTATTAAATTAAAACTATAGTTTTATAATAACTTTTTACTTTTTAAAAAATAGGACTATAATATTAATA
ATTTCAAAAATGGAGGCAAA

Downstream 100 bases:

>100_bases
ATTTAAGAAAAGAAAAAAGAGGATATAAAAATGTTATTAAGCAGTTTTAAAGAAACATTCCTTCAAAACTTTTTAAGCAT
AAGCACATGACAATCACTTT

Product: NADH oxidase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKTVIIGGSATGMGVAAKLKRLNEQNEIVVIQDKDYVSLGACGIPYYIGHNFENPETLIARKIEKFEESQISVISNSKVN
KIDFENKKVIFEESQISYDNLVIAVGAKPITPEIKNIDAKNIFTVNSKEDAIEIRKTINDDSNVLIIGSGLIGLEMVENI
KHSTAAKISIIEKADRVLKNLFDEEFSELVEKEILNQEIELFKNNEVIEFVKDNNGKVTGAKTINGEIIKCDVVILSIGV
IPNTSFLRDTDLELENNGAIKINEYCETNIPNVYAGGDCCSSLSYLYKNTRTFYLATVANKQAKIIANNVNKNKSSKFVG
ALGTTIIRFFDLELARTGENRMFIDMNSIETKEVLIKDKDHTNYVTGQEDIWLKVIIDVKTKEIINVQMIGKNKSVLRIY
GLVGLIWSRSKVDETLEQIDLPYSPPFSRTTDIIHIALSKLI

Sequences:

>Translated_442_residues
MKTVIIGGSATGMGVAAKLKRLNEQNEIVVIQDKDYVSLGACGIPYYIGHNFENPETLIARKIEKFEESQISVISNSKVN
KIDFENKKVIFEESQISYDNLVIAVGAKPITPEIKNIDAKNIFTVNSKEDAIEIRKTINDDSNVLIIGSGLIGLEMVENI
KHSTAAKISIIEKADRVLKNLFDEEFSELVEKEILNQEIELFKNNEVIEFVKDNNGKVTGAKTINGEIIKCDVVILSIGV
IPNTSFLRDTDLELENNGAIKINEYCETNIPNVYAGGDCCSSLSYLYKNTRTFYLATVANKQAKIIANNVNKNKSSKFVG
ALGTTIIRFFDLELARTGENRMFIDMNSIETKEVLIKDKDHTNYVTGQEDI*LKVIIDVKTKEIINVQMIGKNKSVLRIY
GLVGLIWSRSKVDETLEQIDLPYSPPFSRTTDIIHIALSKLI
>Mature_442_residues
MKTVIIGGSATGMGVAAKLKRLNEQNEIVVIQDKDYVSLGACGIPYYIGHNFENPETLIARKIEKFEESQISVISNSKVN
KIDFENKKVIFEESQISYDNLVIAVGAKPITPEIKNIDAKNIFTVNSKEDAIEIRKTINDDSNVLIIGSGLIGLEMVENI
KHSTAAKISIIEKADRVLKNLFDEEFSELVEKEILNQEIELFKNNEVIEFVKDNNGKVTGAKTINGEIIKCDVVILSIGV
IPNTSFLRDTDLELENNGAIKINEYCETNIPNVYAGGDCCSSLSYLYKNTRTFYLATVANKQAKIIANNVNKNKSSKFVG
ALGTTIIRFFDLELARTGENRMFIDMNSIETKEVLIKDKDHTNYVTGQEDI*LKVIIDVKTKEIINVQMIGKNKSVLRIY
GLVGLIWSRSKVDETLEQIDLPYSPPFSRTTDIIHIALSKLI

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=314, Percent_Identity=25.4777070063694, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI226437568, Length=314, Percent_Identity=25.4777070063694, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI21389617, Length=314, Percent_Identity=25.4777070063694, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1789065, Length=215, Percent_Identity=26.5116279069767, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788892, Length=214, Percent_Identity=26.1682242990654, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082354, Length=302, Percent_Identity=24.1721854304636, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789765, Length=337, Percent_Identity=21.9584569732938, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786307, Length=222, Percent_Identity=25.6756756756757, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17559934, Length=223, Percent_Identity=23.3183856502242, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI32565766, Length=309, Percent_Identity=22.6537216828479, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24639257, Length=329, Percent_Identity=24.0121580547112, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281359715, Length=329, Percent_Identity=24.0121580547112, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281359713, Length=329, Percent_Identity=24.0121580547112, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24639250, Length=329, Percent_Identity=24.0121580547112, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI18543267, Length=329, Percent_Identity=24.0121580547112, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24639252, Length=329, Percent_Identity=24.0121580547112, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24585130, Length=183, Percent_Identity=26.2295081967213, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 49278; Mature: 49278

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVIIGGSATGMGVAAKLKRLNEQNEIVVIQDKDYVSLGACGIPYYIGHNFENPETLIA
CCEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCEEEECCCCCCCEECCCCCCHHHHHH
RKIEKFEESQISVISNSKVNKIDFENKKVIFEESQISYDNLVIAVGAKPITPEIKNIDAK
HHHHHHHHCCEEEECCCCCEEEECCCCEEEEECCCCCCCCEEEEECCCCCCCHHHCCCCC
NIFTVNSKEDAIEIRKTINDDSNVLIIGSGLIGLEMVENIKHSTAAKISIIEKADRVLKN
CEEEECCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHEEHHHHHHHHHHHH
LFDEEFSELVEKEILNQEIELFKNNEVIEFVKDNNGKVTGAKTINGEIIKCDVVILSIGV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCEEEEEEEEEEEEC
IPNTSFLRDTDLELENNGAIKINEYCETNIPNVYAGGDCCSSLSYLYKNTRTFYLATVAN
CCCCCCEECCCCEECCCCCEEECCCCCCCCCCEEECCHHHHHHHHHHCCCCEEEEEEECC
KQAKIIANNVNKNKSSKFVGALGTTIIRFFDLELARTGENRMFIDMNSIETKEVLIKDKD
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCEEEEEECCC
HTNYVTGQEDILKVIIDVKTKEIINVQMIGKNKSVLRIYGLVGLIWSRSKVDETLEQIDL
CCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEHHHHHHCHHHHHHHHHHCCC
PYSPPFSRTTDIIHIALSKLI
CCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKTVIIGGSATGMGVAAKLKRLNEQNEIVVIQDKDYVSLGACGIPYYIGHNFENPETLIA
CCEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCEEEECCCCCCCEECCCCCCHHHHHH
RKIEKFEESQISVISNSKVNKIDFENKKVIFEESQISYDNLVIAVGAKPITPEIKNIDAK
HHHHHHHHCCEEEECCCCCEEEECCCCEEEEECCCCCCCCEEEEECCCCCCCHHHCCCCC
NIFTVNSKEDAIEIRKTINDDSNVLIIGSGLIGLEMVENIKHSTAAKISIIEKADRVLKN
CEEEECCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHEEHHHHHHHHHHHH
LFDEEFSELVEKEILNQEIELFKNNEVIEFVKDNNGKVTGAKTINGEIIKCDVVILSIGV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCEEEEEEEEEEEEC
IPNTSFLRDTDLELENNGAIKINEYCETNIPNVYAGGDCCSSLSYLYKNTRTFYLATVAN
CCCCCCEECCCCEECCCCCEEECCCCCCCCCCEEECCHHHHHHHHHHCCCCEEEEEEECC
KQAKIIANNVNKNKSSKFVGALGTTIIRFFDLELARTGENRMFIDMNSIETKEVLIKDKD
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCEEEEEECCC
HTNYVTGQEDILKVIIDVKTKEIINVQMIGKNKSVLRIYGLVGLIWSRSKVDETLEQIDL
CCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEHHHHHHCHHHHHHHHHHCCC
PYSPPFSRTTDIIHIALSKLI
CCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA