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The map label for this gene is nrnA [H]

Identifier: 50365451

GI number: 50365451

Start: 741580

End: 742524

Strand: Reverse

Name: nrnA [H]

Synonym: Mfl636

Alternate gene names: 50365451

Gene position: 742524-741580 (Counterclockwise)

Preceding gene: 50365452

Following gene: 50365450

Centisome position: 93.61

GC content: 26.46

Gene sequence:

>945_bases
ATGAAAGAAACAAATTACAAATTATTAATTAAAAAAATTAAAAAATACAAAAATATTATTATTTTAAAACATATAAGACC
TGATTGAGATGCACAAGGTAGCTCAATGGGTTTAGCGTACCTAATTCAAGAAAATTTCCCAGGTAAAACAATAGTTGTTC
CTGGTGATAGACTTGATGATAACAAAGACTTTTTAAAAAGTAAAATATCAAATGATTTTATTAAATCAGCATTAGTTATC
ACAGTTGACACTGCAACAAAATCAAGATTAGATTTTGATAAATATGATATTGCAGTTGAAACATTTAAAATTGATCACCA
TGTTAATATTGATCCATATGCAAAAAATGAAATTGTCAAAGAAACAGCAATGGCATGTACTGAAGTTATAACTTTATGAG
CAGATGCTATGAAACTAAAATGAAATGCAAATGCAGCGTCAAATCTTTACAAAGGTTTAGTTACAGATAGTGGAAGATTT
TTATTTCCAAATACAAGCTTTAAAACTTTTAATGCAGCTAAAATTCTTTTAGAAAATGGTGCAAATTTAAAAGCAGTACA
TGATTCACTTTTTGTTTCAGATTTAAAAAGAAAACAATATGCAAACTTTGCATTTTCAAAATTACAATTATCTAAAAAAG
GTGTTGGTCATATTACAATTACAAAAGAAGACCAAAAACCTTGAAAATACTCATATGAAGAAATTAAATCAGCATTAGGG
ACTATGAGTGGTATTGATGAAATAAAAATTTGAGTTTTAGTTATTGAATTAGATGAAGAAATTAAAGTTTCAATTAGAAG
TAGAGATTTTGAAATTGATAAAGTAGCTAATAAGTATGATGGTGGTGGACATAAATTAGCAAGTGGATGTAAGTTAAATA
CACTATCTGATATATCAAAACTTGTTAAAGACTTAGACGCTGTTATAACAAAAGGAAACAAATAG

Upstream 100 bases:

>100_bases
ATATTTTTATTCTGAAGATAAAACATTTGAAAGAGAAAATGAAGCAGTTCTTTATTTTGAAGAACATTCAATATCAGCAA
TAATATAAAGGAAAAAAGAA

Downstream 100 bases:

>100_bases
TTATGATACCTAACAGAGATACAATTGAACAAAAACAGTTAGGTTGAGTAGAATTAATAACTGGATGTATGTTTGCTGGT
AAAACAGAAGAGTTTATCAA

Product: exopolyphosphatase-like

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKETNYKLLIKKIKKYKNIIILKHIRPDWDAQGSSMGLAYLIQENFPGKTIVVPGDRLDDNKDFLKSKISNDFIKSALVI
TVDTATKSRLDFDKYDIAVETFKIDHHVNIDPYAKNEIVKETAMACTEVITLWADAMKLKWNANAASNLYKGLVTDSGRF
LFPNTSFKTFNAAKILLENGANLKAVHDSLFVSDLKRKQYANFAFSKLQLSKKGVGHITITKEDQKPWKYSYEEIKSALG
TMSGIDEIKIWVLVIELDEEIKVSIRSRDFEIDKVANKYDGGGHKLASGCKLNTLSDISKLVKDLDAVITKGNK

Sequences:

>Translated_314_residues
MKETNYKLLIKKIKKYKNIIILKHIRPD*DAQGSSMGLAYLIQENFPGKTIVVPGDRLDDNKDFLKSKISNDFIKSALVI
TVDTATKSRLDFDKYDIAVETFKIDHHVNIDPYAKNEIVKETAMACTEVITL*ADAMKLK*NANAASNLYKGLVTDSGRF
LFPNTSFKTFNAAKILLENGANLKAVHDSLFVSDLKRKQYANFAFSKLQLSKKGVGHITITKEDQKP*KYSYEEIKSALG
TMSGIDEIKI*VLVIELDEEIKVSIRSRDFEIDKVANKYDGGGHKLASGCKLNTLSDISKLVKDLDAVITKGNK
>Mature_314_residues
MKETNYKLLIKKIKKYKNIIILKHIRPD*DAQGSSMGLAYLIQENFPGKTIVVPGDRLDDNKDFLKSKISNDFIKSALVI
TVDTATKSRLDFDKYDIAVETFKIDHHVNIDPYAKNEIVKETAMACTEVITL*ADAMKLK*NANAASNLYKGLVTDSGRF
LFPNTSFKTFNAAKILLENGANLKAVHDSLFVSDLKRKQYANFAFSKLQLSKKGVGHITITKEDQKP*KYSYEEIKSALG
TMSGIDEIKI*VLVIELDEEIKVSIRSRDFEIDKVANKYDGGGHKLASGCKLNTLSDISKLVKDLDAVITKGNK

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 34412; Mature: 34412

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETNYKLLIKKIKKYKNIIILKHIRPDDAQGSSMGLAYLIQENFPGKTIVVPGDRLDDN
CCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCC
KDFLKSKISNDFIKSALVITVDTATKSRLDFDKYDIAVETFKIDHHVNIDPYAKNEIVKE
HHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHEEEEEEEEEEEECCCCCCHHHHHHHH
TAMACTEVITLADAMKLKNANAASNLYKGLVTDSGRFLFPNTSFKTFNAAKILLENGANL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCHHEEEEEECCCCE
KAVHDSLFVSDLKRKQYANFAFSKLQLSKKGVGHITITKEDQKPKYSYEEIKSALGTMSG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
IDEIKIVLVIELDEEIKVSIRSRDFEIDKVANKYDGGGHKLASGCKLNTLSDISKLVKDL
CCCEEEEEEEEECCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
DAVITKGNK
HHHHCCCCC
>Mature Secondary Structure
MKETNYKLLIKKIKKYKNIIILKHIRPDDAQGSSMGLAYLIQENFPGKTIVVPGDRLDDN
CCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCC
KDFLKSKISNDFIKSALVITVDTATKSRLDFDKYDIAVETFKIDHHVNIDPYAKNEIVKE
HHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHEEEEEEEEEEEECCCCCCHHHHHHHH
TAMACTEVITLADAMKLKNANAASNLYKGLVTDSGRFLFPNTSFKTFNAAKILLENGANL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCHHEEEEEECCCCE
KAVHDSLFVSDLKRKQYANFAFSKLQLSKKGVGHITITKEDQKPKYSYEEIKSALGTMSG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
IDEIKIVLVIELDEEIKVSIRSRDFEIDKVANKYDGGGHKLASGCKLNTLSDISKLVKDL
CCCEEEEEEEEECCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
DAVITKGNK
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]